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The map label for this gene is dsbD [H]

Identifier: 83594388

GI number: 83594388

Start: 3520875

End: 3523022

Strand: Reverse

Name: dsbD [H]

Synonym: Rru_A3058

Alternate gene names: 83594388

Gene position: 3523022-3520875 (Counterclockwise)

Preceding gene: 83594391

Following gene: 83594387

Centisome position: 80.94

GC content: 70.86

Gene sequence:

>2148_bases
ATGTCGCGTTTCCTTCTTGCCCTCTGCCTGTTTCTTGGCTTGTGCCTGCCGGCCCAGGCCCAGGGAAACGACCCCGGCGC
CTCGGCCTGGGTTGAGAAAAGCCATTCGCGGATGCGGCTGATTTCGGCCGTCAGCGCCGCGGGCAAGGCCGAAGAGATCG
CTTTGGGCCTGCAGGTCGAGCTTGCCCCCCATTGGAAGATCTATTGGCGCAGCCCGGGGGATGCGGGCTATCCGCCGTCG
TTTGACTGGACCGGCTCGCTCAATTTGGCCGGGGCCACGCCGCGATGGCCGGTGCCGACACGCTTTTCGGTTCTGGGGAT
CGAGACCGTCGGCTATGAGCATCAGGTGATCTTGCCCTTGATGGCCCGCCTTGAGCGCCCCGGCGATCCGCTGATCCTGC
GCCTCGCCGTCGATTATCTGATCTGCGCCGAGGTCTGCGTGCCCGATCGCGGGGATTTCACCCTGATCGTGCCCCCCGGA
CCGTCGGGGGCCAGCCCGCAGGCCCAAGCCCTGGCCCGCTTCCTGGCCCAGGTGCCCGGCCCCAGCCCCTCGCATGGCAT
CACGGTTGACGAAGCGGTGATCGAGACCGGCGGCGTGGTGCGGGTGGCGGTGCGCGCCGATCCGCCACTGGCCGCCCCCG
ATCTGTTCGTCGAGGCCCCGGCGGGCATGGCCTTCGCCCGGCCCCAGGTTACGGTGGAGGAGGGCGGGGGGCGCGCCGTT
TTGCGGGCCGGAGTGGTCGGCGGCGACGCGTTGATCGGCCAGAGCCTGCCGGTGCTGGTCGCCGATGGTGTGCGCGGCGT
GGAGGCCGGGGTTGATACGAGGCGGGCGCTGGCGCCGCCGGCCGGGGCGGGCGATCCCCGGCCGACCGCCCTTGGCGGAG
AGAGCGGCGGAGAGACCGGCGCCCCGGGCGCGCCAACGGGGCCGCTCGCTTTCCTGGCGATGGTCAGCGTCGCCCTGCTT
GGCGGCCTGATCCTTAATTTGATGCCCTGCGTGCTGCCGGTGCTGTCGCTGAAGATCCTTGGACTGGTCGGCCATGGGGG
CGGGGCGCCGCGCGCCGCCCGGCTGTCGTTTCTGGCGACCAGCGCCGGAATCATCGCCAGTTTCCTGGTTCTGGCCCTTG
CCGCCATCGGCCTGAAAACCGCCGGCATGGCGGTGGGCTGGGGCATTCAGTTCCAGCAGCCGCTGTTCTTGTCGGGCATG
GTCGTGCTGCTGGCGCTGTTCGCCGCCAATCTGTGGGGATTGTTCGAGATCGGGCTGCCCGGCGCGGTTTCGGGGCTGGG
CGGCCAAGGTCGTGCGGGCTCGTCGTTGAGCGGGGCCTTCGCCACCGGGGCCTTCGCCACCGTGCTGGCCACGCCGTGCT
CGGCGCCCTTCCTGGGAACCGCCGTCGGCTTCGCCCTGGCGCGCGGGCCCTTTGAAATTCTGGCGATCTTCCTGGCGCTT
GGCCTGGGCATGGCCTTGCCCTATCTGCTGGTGGCCCTGCGCCCGCAGATCGCCACCCGTCTGCCCCGGCCGGGGCGCTG
GATGCTGCGGTTGAAGGCGGTTCTGGGGGCGGTTCTGTGCCTGACCGCCCTGTGGCTGCTCAGCGTTCTCGCCGTGCAGA
TCGGCGCGGTTTGGGCGGCGGTGATCGGCGGCTTGCTGGCCGTGGCGCTGGGGGTGCGGGCCTTGCGGCCGATCTCGCGG
CTGTCGGGCGGGGTGGCGGCGCTGCTGGGGATCGCTGCCCTCGCCCTACCGGCCTTGCCCTTGCCCGCCCTGTCGCTGCC
GATGGCGGCACCCTCTCAGGCCCTTGAGGAAACCGCCTGGGGCCGCTGGTCGCCCGAGGCGGTGGCGCGGCTGGTGGCCG
AGGGCAAGACGGTGCTCGTCGATGTGACCGCCCAATGGTGCGTGACCTGCAAGGTCAATAAGGCCACGGTTCTTGACGCC
GCGCCAACGCGGGCCTTGCTCGACTCGGGGCGGCTGAGCGGTTTGCGGGCCGATTGGACCCGTCCTGATCCGGCGATCGC
CGCCTATCTGGCCTCCTTCGGCCGCTTCGGCATCCCCTTCAACGCGGTTTATGGCCCGGGCGCCCCCCAGGGCATAGCCC
TGCCCGAGCTTCTGAGCGAAAACGCCTTGCTGGAGGCCGTGGCCCGGGCGGCGGGGCCTTCGTCCTGA

Upstream 100 bases:

>100_bases
ACGTCGCCGCCGTGGCCACAGCGCCTCATCGCGCCGCTTTCCCACCCCTGCGGAAGCGGGCTTCTTCGCGTTCTGCACAC
CCGAATGACCTGGGGGTCCG

Downstream 100 bases:

>100_bases
AAAGGGGGGGTGTCGGTCCCCCCGGGCGCTCCCATATGAGCGTCACCTTTGGCTTATGGAGAGAGTTCATGATCGCCGTT
GGAGACGCTTTGCCTTCGGG

Product: putative suppressor for copper-sensitivity B

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MSRFLLALCLFLGLCLPAQAQGNDPGASAWVEKSHSRMRLISAVSAAGKAEEIALGLQVELAPHWKIYWRSPGDAGYPPS
FDWTGSLNLAGATPRWPVPTRFSVLGIETVGYEHQVILPLMARLERPGDPLILRLAVDYLICAEVCVPDRGDFTLIVPPG
PSGASPQAQALARFLAQVPGPSPSHGITVDEAVIETGGVVRVAVRADPPLAAPDLFVEAPAGMAFARPQVTVEEGGGRAV
LRAGVVGGDALIGQSLPVLVADGVRGVEAGVDTRRALAPPAGAGDPRPTALGGESGGETGAPGAPTGPLAFLAMVSVALL
GGLILNLMPCVLPVLSLKILGLVGHGGGAPRAARLSFLATSAGIIASFLVLALAAIGLKTAGMAVGWGIQFQQPLFLSGM
VVLLALFAANLWGLFEIGLPGAVSGLGGQGRAGSSLSGAFATGAFATVLATPCSAPFLGTAVGFALARGPFEILAIFLAL
GLGMALPYLLVALRPQIATRLPRPGRWMLRLKAVLGAVLCLTALWLLSVLAVQIGAVWAAVIGGLLAVALGVRALRPISR
LSGGVAALLGIAALALPALPLPALSLPMAAPSQALEETAWGRWSPEAVARLVAEGKTVLVDVTAQWCVTCKVNKATVLDA
APTRALLDSGRLSGLRADWTRPDPAIAAYLASFGRFGIPFNAVYGPGAPQGIALPELLSENALLEAVARAAGPSS

Sequences:

>Translated_715_residues
MSRFLLALCLFLGLCLPAQAQGNDPGASAWVEKSHSRMRLISAVSAAGKAEEIALGLQVELAPHWKIYWRSPGDAGYPPS
FDWTGSLNLAGATPRWPVPTRFSVLGIETVGYEHQVILPLMARLERPGDPLILRLAVDYLICAEVCVPDRGDFTLIVPPG
PSGASPQAQALARFLAQVPGPSPSHGITVDEAVIETGGVVRVAVRADPPLAAPDLFVEAPAGMAFARPQVTVEEGGGRAV
LRAGVVGGDALIGQSLPVLVADGVRGVEAGVDTRRALAPPAGAGDPRPTALGGESGGETGAPGAPTGPLAFLAMVSVALL
GGLILNLMPCVLPVLSLKILGLVGHGGGAPRAARLSFLATSAGIIASFLVLALAAIGLKTAGMAVGWGIQFQQPLFLSGM
VVLLALFAANLWGLFEIGLPGAVSGLGGQGRAGSSLSGAFATGAFATVLATPCSAPFLGTAVGFALARGPFEILAIFLAL
GLGMALPYLLVALRPQIATRLPRPGRWMLRLKAVLGAVLCLTALWLLSVLAVQIGAVWAAVIGGLLAVALGVRALRPISR
LSGGVAALLGIAALALPALPLPALSLPMAAPSQALEETAWGRWSPEAVARLVAEGKTVLVDVTAQWCVTCKVNKATVLDA
APTRALLDSGRLSGLRADWTRPDPAIAAYLASFGRFGIPFNAVYGPGAPQGIALPELLSENALLEAVARAAGPSS
>Mature_714_residues
SRFLLALCLFLGLCLPAQAQGNDPGASAWVEKSHSRMRLISAVSAAGKAEEIALGLQVELAPHWKIYWRSPGDAGYPPSF
DWTGSLNLAGATPRWPVPTRFSVLGIETVGYEHQVILPLMARLERPGDPLILRLAVDYLICAEVCVPDRGDFTLIVPPGP
SGASPQAQALARFLAQVPGPSPSHGITVDEAVIETGGVVRVAVRADPPLAAPDLFVEAPAGMAFARPQVTVEEGGGRAVL
RAGVVGGDALIGQSLPVLVADGVRGVEAGVDTRRALAPPAGAGDPRPTALGGESGGETGAPGAPTGPLAFLAMVSVALLG
GLILNLMPCVLPVLSLKILGLVGHGGGAPRAARLSFLATSAGIIASFLVLALAAIGLKTAGMAVGWGIQFQQPLFLSGMV
VLLALFAANLWGLFEIGLPGAVSGLGGQGRAGSSLSGAFATGAFATVLATPCSAPFLGTAVGFALARGPFEILAIFLALG
LGMALPYLLVALRPQIATRLPRPGRWMLRLKAVLGAVLCLTALWLLSVLAVQIGAVWAAVIGGLLAVALGVRALRPISRL
SGGVAALLGIAALALPALPLPALSLPMAAPSQALEETAWGRWSPEAVARLVAEGKTVLVDVTAQWCVTCKVNKATVLDAA
PTRALLDSGRLSGLRADWTRPDPAIAAYLASFGRFGIPFNAVYGPGAPQGIALPELLSENALLEAVARAAGPSS

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=394, Percent_Identity=29.4416243654822, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 72961; Mature: 72830

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFLLALCLFLGLCLPAQAQGNDPGASAWVEKSHSRMRLISAVSAAGKAEEIALGLQVE
CHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEE
LAPHWKIYWRSPGDAGYPPSFDWTGSLNLAGATPRWPVPTRFSVLGIETVGYEHQVILPL
ECCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
MARLERPGDPLILRLAVDYLICAEVCVPDRGDFTLIVPPGPSGASPQAQALARFLAQVPG
HHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCC
PSPSHGITVDEAVIETGGVVRVAVRADPPLAAPDLFVEAPAGMAFARPQVTVEEGGGRAV
CCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCEEECCCCCEECCCCEEEECCCCEEE
LRAGVVGGDALIGQSLPVLVADGVRGVEAGVDTRRALAPPAGAGDPRPTALGGESGGETG
EEECCCCCHHHHCCCCCEEEECCCCHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCC
APGAPTGPLAFLAMVSVALLGGLILNLMPCVLPVLSLKILGLVGHGGGAPRAARLSFLAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHH
SAGIIASFLVLALAAIGLKTAGMAVGWGIQFQQPLFLSGMVVLLALFAANLWGLFEIGLP
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GAVSGLGGQGRAGSSLSGAFATGAFATVLATPCSAPFLGTAVGFALARGPFEILAIFLAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
GLGMALPYLLVALRPQIATRLPRPGRWMLRLKAVLGAVLCLTALWLLSVLAVQIGAVWAA
HHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGGLLAVALGVRALRPISRLSGGVAALLGIAALALPALPLPALSLPMAAPSQALEETAW
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCC
GRWSPEAVARLVAEGKTVLVDVTAQWCVTCKVNKATVLDAAPTRALLDSGRLSGLRADWT
CCCCHHHHHHHHHCCCEEEEEEEEEEEEEEECCCEEEECCCCHHHHHHCCCCCCCCCCCC
RPDPAIAAYLASFGRFGIPFNAVYGPGAPQGIALPELLSENALLEAVARAAGPSS
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRFLLALCLFLGLCLPAQAQGNDPGASAWVEKSHSRMRLISAVSAAGKAEEIALGLQVE
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEE
LAPHWKIYWRSPGDAGYPPSFDWTGSLNLAGATPRWPVPTRFSVLGIETVGYEHQVILPL
ECCCEEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHH
MARLERPGDPLILRLAVDYLICAEVCVPDRGDFTLIVPPGPSGASPQAQALARFLAQVPG
HHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCC
PSPSHGITVDEAVIETGGVVRVAVRADPPLAAPDLFVEAPAGMAFARPQVTVEEGGGRAV
CCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCEEECCCCCEECCCCEEEECCCCEEE
LRAGVVGGDALIGQSLPVLVADGVRGVEAGVDTRRALAPPAGAGDPRPTALGGESGGETG
EEECCCCCHHHHCCCCCEEEECCCCHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCC
APGAPTGPLAFLAMVSVALLGGLILNLMPCVLPVLSLKILGLVGHGGGAPRAARLSFLAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHH
SAGIIASFLVLALAAIGLKTAGMAVGWGIQFQQPLFLSGMVVLLALFAANLWGLFEIGLP
HHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GAVSGLGGQGRAGSSLSGAFATGAFATVLATPCSAPFLGTAVGFALARGPFEILAIFLAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
GLGMALPYLLVALRPQIATRLPRPGRWMLRLKAVLGAVLCLTALWLLSVLAVQIGAVWAA
HHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGGLLAVALGVRALRPISRLSGGVAALLGIAALALPALPLPALSLPMAAPSQALEETAW
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCC
GRWSPEAVARLVAEGKTVLVDVTAQWCVTCKVNKATVLDAAPTRALLDSGRLSGLRADWT
CCCCHHHHHHHHHCCCEEEEEEEEEEEEEEECCCEEEECCCCHHHHHHCCCCCCCCCCCC
RPDPAIAAYLASFGRFGIPFNAVYGPGAPQGIALPELLSENALLEAVARAAGPSS
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]