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The map label for this gene is lysN [H]

Identifier: 83594334

GI number: 83594334

Start: 3460709

End: 3461944

Strand: Reverse

Name: lysN [H]

Synonym: Rru_A3004

Alternate gene names: 83594334

Gene position: 3461944-3460709 (Counterclockwise)

Preceding gene: 83594336

Following gene: 83594331

Centisome position: 79.53

GC content: 65.53

Gene sequence:

>1236_bases
ATGGACTGGAAGGGCGCCTACGCCCACCGGGCGGGGGCGATGCGGGCCTCGGAGATCCGCGAGCTTCTGAAGCTTCTTGA
TCAGCCGGATGTCTTGTCCTTTGCCGGCGGTATTCCCGATCCGACGCTGTTTCCCACCGAGGCGGCGCGCGAGGCCTATG
GCGCGGTGCTTGGCGAACCCGGCGTCGGCCCGCTGTCCCTGCAATATTCGATCAGCGAGGGCTATGTGCCCCTGCGTCGC
TGGATCGTCGCCCATATGGCCAGCCGTGGCGTGGTCTGCGACGAGGAGAACATCGTCATCACCTCGGGGTCGCAGCAGGG
GCTTGATTATCTTGGCAAGCTGCTGATTTCACCCGGCGATAGCGCCTATGTCACCCGCCCGACCTATCTGGGGGCGCTTC
AGGCCTTCAACCCCTATGAACCGCGCTATGCCGATCTGGCCTTTGGCGAGGGCGCTCCGACGCCCGCCCAATGCCGCGAG
GCGGCGCTGGCGGCCGGCGGTCGTCCGGCCTTGGCCTATGTGGTTCCCGATTTCGCCAATCCGACCGGGGAAACGCTGAG
CCGCGAGGATCGCCTGCGCCTGCTTGAGCATGTCAGCGCCCTGGGGGTGCCGTTGGTCGAGGACGCCGCCTATGCCGCGT
TGCGCTATGCCGGGGCCGATATCGCCTCGTGTCTGGCCCTTGATATCGCCCGCGTCGGCGATATCGACCACAGCCGGGTG
ATTTATTGCGGCTCGTTCTCCAAGACCATCGCCCCGGGCCTGCGCGTGGGCTGGATCTGCGCGGCCCGCGATCTGGTGCA
AAAGGTGGTGCTGACCAAGCAGGCCGCCGATTTGCACAGCGCCACGATCAATCAGATGGTCATGCATCGGCTGGCCGAGG
CGATCTATGACGAGCAGGTCAAAAAAATCATTGGCGTCTATGCCGCCCGCCGCGACGCCCTGCTTGCCGCCCTGGCCAAA
TTCATGCCCGAAGGCGTGAGTTGGACGGCGCCCGAAGGCGGGATGTTCGTTTGGGTGACCCTGCCGGCGAATATCGATGG
CGCCGAGTTGTTGGCGGAGTCGCTGCGCGACGAGCGGGTGGCCTTCGTTCCCGGCGGCGCCTTTTTCTTCGATGGCAGCG
GCGCCAATACCTTGCGCCTGAACTTCTCGCTGCCCTCGGAAGCCGTCATCAACGAGGGCATCGCCCGTCTGGCCCGGCTG
ATCGCCCGCAAGAACAACCAGTTCCGCGCCGCCTGA

Upstream 100 bases:

>100_bases
TTTCTAAAGAGCGTGCGCCGAGCCCCGGCATCGGTACGCCCCGGTTTTCTGAAGGCGGGCCCATCCTTGTGGCCGCCTGT
TTGTGGAGGGTTATAAGGTG

Downstream 100 bases:

>100_bases
CGGGCGCCCATCCGCCGCGCCCCCCTCCGTGTCGCCCTCTGATCGCGAGCGCGACGACGATTTGCCTTAGGCGCGGCGGA
TGGTGCGATAGGCGAAATCC

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDWKGAYAHRAGAMRASEIRELLKLLDQPDVLSFAGGIPDPTLFPTEAAREAYGAVLGEPGVGPLSLQYSISEGYVPLRR
WIVAHMASRGVVCDEENIVITSGSQQGLDYLGKLLISPGDSAYVTRPTYLGALQAFNPYEPRYADLAFGEGAPTPAQCRE
AALAAGGRPALAYVVPDFANPTGETLSREDRLRLLEHVSALGVPLVEDAAYAALRYAGADIASCLALDIARVGDIDHSRV
IYCGSFSKTIAPGLRVGWICAARDLVQKVVLTKQAADLHSATINQMVMHRLAEAIYDEQVKKIIGVYAARRDALLAALAK
FMPEGVSWTAPEGGMFVWVTLPANIDGAELLAESLRDERVAFVPGGAFFFDGSGANTLRLNFSLPSEAVINEGIARLARL
IARKNNQFRAA

Sequences:

>Translated_411_residues
MDWKGAYAHRAGAMRASEIRELLKLLDQPDVLSFAGGIPDPTLFPTEAAREAYGAVLGEPGVGPLSLQYSISEGYVPLRR
WIVAHMASRGVVCDEENIVITSGSQQGLDYLGKLLISPGDSAYVTRPTYLGALQAFNPYEPRYADLAFGEGAPTPAQCRE
AALAAGGRPALAYVVPDFANPTGETLSREDRLRLLEHVSALGVPLVEDAAYAALRYAGADIASCLALDIARVGDIDHSRV
IYCGSFSKTIAPGLRVGWICAARDLVQKVVLTKQAADLHSATINQMVMHRLAEAIYDEQVKKIIGVYAARRDALLAALAK
FMPEGVSWTAPEGGMFVWVTLPANIDGAELLAESLRDERVAFVPGGAFFFDGSGANTLRLNFSLPSEAVINEGIARLARL
IARKNNQFRAA
>Mature_411_residues
MDWKGAYAHRAGAMRASEIRELLKLLDQPDVLSFAGGIPDPTLFPTEAAREAYGAVLGEPGVGPLSLQYSISEGYVPLRR
WIVAHMASRGVVCDEENIVITSGSQQGLDYLGKLLISPGDSAYVTRPTYLGALQAFNPYEPRYADLAFGEGAPTPAQCRE
AALAAGGRPALAYVVPDFANPTGETLSREDRLRLLEHVSALGVPLVEDAAYAALRYAGADIASCLALDIARVGDIDHSRV
IYCGSFSKTIAPGLRVGWICAARDLVQKVVLTKQAADLHSATINQMVMHRLAEAIYDEQVKKIIGVYAARRDALLAALAK
FMPEGVSWTAPEGGMFVWVTLPANIDGAELLAESLRDERVAFVPGGAFFFDGSGANTLRLNFSLPSEAVINEGIARLARL
IARKNNQFRAA

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=423, Percent_Identity=29.3144208037825, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI33469970, Length=423, Percent_Identity=29.3144208037825, Blast_Score=182, Evalue=5e-46,
Organism=Escherichia coli, GI1787710, Length=387, Percent_Identity=25.3229974160207, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1790797, Length=338, Percent_Identity=24.8520710059172, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788722, Length=349, Percent_Identity=26.0744985673352, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321000, Length=422, Percent_Identity=24.6445497630332, Blast_Score=89, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21356535, Length=415, Percent_Identity=24.8192771084337, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 44147; Mature: 44147

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWKGAYAHRAGAMRASEIRELLKLLDQPDVLSFAGGIPDPTLFPTEAAREAYGAVLGEP
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
GVGPLSLQYSISEGYVPLRRWIVAHMASRGVVCDEENIVITSGSQQGLDYLGKLLISPGD
CCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHHCCCCC
SAYVTRPTYLGALQAFNPYEPRYADLAFGEGAPTPAQCREAALAAGGRPALAYVVPDFAN
CCEEECCHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
PTGETLSREDRLRLLEHVSALGVPLVEDAAYAALRYAGADIASCLALDIARVGDIDHSRV
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCE
IYCGSFSKTIAPGLRVGWICAARDLVQKVVLTKQAADLHSATINQMVMHRLAEAIYDEQV
EEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKIIGVYAARRDALLAALAKFMPEGVSWTAPEGGMFVWVTLPANIDGAELLAESLRDERV
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCE
AFVPGGAFFFDGSGANTLRLNFSLPSEAVINEGIARLARLIARKNNQFRAA
EEECCCEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDWKGAYAHRAGAMRASEIRELLKLLDQPDVLSFAGGIPDPTLFPTEAAREAYGAVLGEP
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
GVGPLSLQYSISEGYVPLRRWIVAHMASRGVVCDEENIVITSGSQQGLDYLGKLLISPGD
CCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHHCCCCC
SAYVTRPTYLGALQAFNPYEPRYADLAFGEGAPTPAQCREAALAAGGRPALAYVVPDFAN
CCEEECCHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCC
PTGETLSREDRLRLLEHVSALGVPLVEDAAYAALRYAGADIASCLALDIARVGDIDHSRV
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCE
IYCGSFSKTIAPGLRVGWICAARDLVQKVVLTKQAADLHSATINQMVMHRLAEAIYDEQV
EEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKIIGVYAARRDALLAALAKFMPEGVSWTAPEGGMFVWVTLPANIDGAELLAESLRDERV
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEECCCCCHHHHHHHHHCCCCE
AFVPGGAFFFDGSGANTLRLNFSLPSEAVINEGIARLARLIARKNNQFRAA
EEECCCEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA