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The map label for this gene is cobH [H]

Identifier: 83594321

GI number: 83594321

Start: 3443275

End: 3443901

Strand: Reverse

Name: cobH [H]

Synonym: Rru_A2991

Alternate gene names: 83594321

Gene position: 3443901-3443275 (Counterclockwise)

Preceding gene: 83594323

Following gene: 83594320

Centisome position: 79.12

GC content: 68.58

Gene sequence:

>627_bases
ATGATCGATTATAGCCGCGACGGCGCCGATATCTACCGGCGGTCCTTTGCCATCATCCGGGCGGAGGCCGATCTTTCGCG
CATCCCGGCCGATCTGGAAAAGCTGGCGGTCCGCGTCGCCCATTCCTGCGGCATGGTCGATGTGATCAATGATCTGGTGT
TCTCGCCCCAGGCCGGAGCGGCCGGGCGGGCGGCCTTGGCCGCCGGGGCGCCGATCCTGTGCGATTGCAAGATGGTGGCC
GAGGGCATCACCCGCTCGCGGCTTGAAGGCGGCAACCCGGTGATCTGCACCCTGGCCGACAGCGGCGTGCCCGAACTGGC
CCGCGAGATGGCCACCACGCGTTCGGCGGCGGCTTTGGAGCTGTGGCGGCCGATGCTGGCCGGGTCGGTGGTCGCCATCG
GCAACGCGCCGACGGCGCTGTTCCGTCTGTTGGAAATGCTTGATGGCGGGGCGCCGCGCCCGGCCTTGATCCTGGGCTTT
CCGGTCGGCTTCGTCGGCGCGGCCGAATCCAAGCAGGAATTGGCCGAGAACAGCCGCGATGTACCCTTTGTCGTGGTGCG
TGGACGGCGCGGCGGCAGCGCGATGACGGTGGCGGCCATCAACGCCCTGGCGACGGAGCGCGAATGA

Upstream 100 bases:

>100_bases
GTTAAAGGATTCTCATTTAACGCGGCGTGATCTATAGGGTATCTGTCCGCCGCCGGAGCGCCGAACGGCGGAGCCGGCTT
TGCCGAGAACGAGGGGTGCG

Downstream 100 bases:

>100_bases
TGGCGGACAAGGGACGGCTGTTTGGCCTGGGCGTCGGTCCGGGCGATCCCGAATTGATCACGCTGAAGGCCCTGAAGCGC
CTGCGGGCGGCGCCGGTGGT

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: HBA synthase; Precorrin isomerase [H]

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MIDYSRDGADIYRRSFAIIRAEADLSRIPADLEKLAVRVAHSCGMVDVINDLVFSPQAGAAGRAALAAGAPILCDCKMVA
EGITRSRLEGGNPVICTLADSGVPELAREMATTRSAAALELWRPMLAGSVVAIGNAPTALFRLLEMLDGGAPRPALILGF
PVGFVGAAESKQELAENSRDVPFVVVRGRRGGSAMTVAAINALATERE

Sequences:

>Translated_208_residues
MIDYSRDGADIYRRSFAIIRAEADLSRIPADLEKLAVRVAHSCGMVDVINDLVFSPQAGAAGRAALAAGAPILCDCKMVA
EGITRSRLEGGNPVICTLADSGVPELAREMATTRSAAALELWRPMLAGSVVAIGNAPTALFRLLEMLDGGAPRPALILGF
PVGFVGAAESKQELAENSRDVPFVVVRGRRGGSAMTVAAINALATERE
>Mature_208_residues
MIDYSRDGADIYRRSFAIIRAEADLSRIPADLEKLAVRVAHSCGMVDVINDLVFSPQAGAAGRAALAAGAPILCDCKMVA
EGITRSRLEGGNPVICTLADSGVPELAREMATTRSAAALELWRPMLAGSVVAIGNAPTALFRLLEMLDGGAPRPALILGF
PVGFVGAAESKQELAENSRDVPFVVVRGRRGGSAMTVAAINALATERE

Specific function: Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: =5.4.1.2 [H]

Molecular weight: Translated: 21775; Mature: 21775

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDYSRDGADIYRRSFAIIRAEADLSRIPADLEKLAVRVAHSCGMVDVINDLVFSPQAGA
CCCCCCCCHHHHHHHHHEEEECCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
AGRAALAAGAPILCDCKMVAEGITRSRLEGGNPVICTLADSGVPELAREMATTRSAAALE
CCCHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
LWRPMLAGSVVAIGNAPTALFRLLEMLDGGAPRPALILGFPVGFVGAAESKQELAENSRD
HHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCHHCCCCCHHHHHHHCCCC
VPFVVVRGRRGGSAMTVAAINALATERE
CCEEEEECCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDYSRDGADIYRRSFAIIRAEADLSRIPADLEKLAVRVAHSCGMVDVINDLVFSPQAGA
CCCCCCCCHHHHHHHHHEEEECCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCC
AGRAALAAGAPILCDCKMVAEGITRSRLEGGNPVICTLADSGVPELAREMATTRSAAALE
CCCHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
LWRPMLAGSVVAIGNAPTALFRLLEMLDGGAPRPALILGFPVGFVGAAESKQELAENSRD
HHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCHHCCCCCHHHHHHHCCCC
VPFVVVRGRRGGSAMTVAAINALATERE
CCEEEEECCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]