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The map label for this gene is crtE [H]

Identifier: 83594313

GI number: 83594313

Start: 3434868

End: 3435737

Strand: Reverse

Name: crtE [H]

Synonym: Rru_A2983

Alternate gene names: 83594313

Gene position: 3435737-3434868 (Counterclockwise)

Preceding gene: 83594319

Following gene: 83594312

Centisome position: 78.93

GC content: 70.57

Gene sequence:

>870_bases
ATGGATGTTCGGCAACATATCGACAACGTTCTTGAAGCCACGATGACCCGGGCGGATCTGCCCGACGCGCCACCCTTGCT
GGCCAAGGCCATGCGCCACGCCGTGTTTCCCGGTGGTGGGCGCCTGCGGCCGCGGTTGACCCTGGCCGTCGCCGCCGCCT
GCGGCAATGACCTGCCCGCCGCCGCCGATGCCGCCGCCGCCGCCATCGAACTGCTCCATTGCGCCTCGCTCGTCCACGAT
GATCTGCCCTGCTTCGACGACGCCCACTCCCGCCGGGGTCAGGCCTCGGTCCATGTCGCCTATGGCGAGCCGCTGGCGGT
TCTGGCCGGCGACGCCCTGATCGTCATGGCCTTCCAGGGCTTGGCCAGCGGTCTGGCCATGGTTCCCGAGCGGTTGCCCC
TGCTGCTGGGCATCGTCGCCGACGCGGTGGGCATGCCCGCCGGCATCTGCGCCGGTCAGGCCTGGGAAAGCGAACCGACG
GTTAAACTGGCCGAATACCAGCGGGCCAAGACCGGCGCCCTGTTCGCCGCCTCGACCATGGCCGGCGCCGCGGCGGCTGG
CCGCGAGGCGCGGTCCTGGCGGATGTTGGGCGAATGCCTGGGCGAGGCCTATCAGGTGGCCGATGATCTGCGCGATGTCG
CCGCCGATCCGGCCGAACTGGGCAAGCCGGTGGGTCGCGACGCGGCGCTGGGACGGCCCAACGCCGTTGGTCATCTGGGA
ATCGTCGGCGCCGTGCGCCGGCTGGAAAGTCTGGTCGCCGATGCGGTGGCCTCGGTGCCCGATTGCGCCGGAGCCGGGGC
GTTGCGCGCGCTTATTCACAAGGAAGCCGAACGCTTCCTGCCCAAGGAACTGGCGCGCTACGCCGCCTGA

Upstream 100 bases:

>100_bases
CGGTGCAATCCCTAAGGGATTAGGGGCCACATGCGGGCATGGCGGGCGGCAAGCCGGCGACCCTGTTTGGCGGCTGTTTT
CGGGGGCGGGAGACGCGATC

Downstream 100 bases:

>100_bases
TCGCTCCGACGCCGCCCTGGCGCCGGAGGTCCGGTTTTCCCGAGCCCGGTTTTCCTGGTCGCGGTGATCCTGACGGAGTC
GGGAGCCGCAAGGGGAACCA

Product: farnesyl-diphosphate synthase

Products: NA

Alternate protein names: GGPP synthase; Farnesyltranstransferase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDVRQHIDNVLEATMTRADLPDAPPLLAKAMRHAVFPGGGRLRPRLTLAVAAACGNDLPAAADAAAAAIELLHCASLVHD
DLPCFDDAHSRRGQASVHVAYGEPLAVLAGDALIVMAFQGLASGLAMVPERLPLLLGIVADAVGMPAGICAGQAWESEPT
VKLAEYQRAKTGALFAASTMAGAAAAGREARSWRMLGECLGEAYQVADDLRDVAADPAELGKPVGRDAALGRPNAVGHLG
IVGAVRRLESLVADAVASVPDCAGAGALRALIHKEAERFLPKELARYAA

Sequences:

>Translated_289_residues
MDVRQHIDNVLEATMTRADLPDAPPLLAKAMRHAVFPGGGRLRPRLTLAVAAACGNDLPAAADAAAAAIELLHCASLVHD
DLPCFDDAHSRRGQASVHVAYGEPLAVLAGDALIVMAFQGLASGLAMVPERLPLLLGIVADAVGMPAGICAGQAWESEPT
VKLAEYQRAKTGALFAASTMAGAAAAGREARSWRMLGECLGEAYQVADDLRDVAADPAELGKPVGRDAALGRPNAVGHLG
IVGAVRRLESLVADAVASVPDCAGAGALRALIHKEAERFLPKELARYAA
>Mature_289_residues
MDVRQHIDNVLEATMTRADLPDAPPLLAKAMRHAVFPGGGRLRPRLTLAVAAACGNDLPAAADAAAAAIELLHCASLVHD
DLPCFDDAHSRRGQASVHVAYGEPLAVLAGDALIVMAFQGLASGLAMVPERLPLLLGIVADAVGMPAGICAGQAWESEPT
VKLAEYQRAKTGALFAASTMAGAAAAGREARSWRMLGECLGEAYQVADDLRDVAADPAELGKPVGRDAALGRPNAVGHLG
IVGAVRRLESLVADAVASVPDCAGAGALRALIHKEAERFLPKELARYAA

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=214, Percent_Identity=31.7757009345794, Blast_Score=78, Evalue=9e-15,
Organism=Escherichia coli, GI1786623, Length=258, Percent_Identity=37.5968992248062, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789578, Length=218, Percent_Identity=32.5688073394495, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17505681, Length=234, Percent_Identity=31.6239316239316, Blast_Score=88, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.29 [H]

Molecular weight: Translated: 29836; Mature: 29836

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRQHIDNVLEATMTRADLPDAPPLLAKAMRHAVFPGGGRLRPRLTLAVAAACGNDLPA
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
AADAAAAAIELLHCASLVHDDLPCFDDAHSRRGQASVHVAYGEPLAVLAGDALIVMAFQG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEECCCCHHHHHCCHHHHHHHHH
LASGLAMVPERLPLLLGIVADAVGMPAGICAGQAWESEPTVKLAEYQRAKTGALFAASTM
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
AGAAAAGREARSWRMLGECLGEAYQVADDLRDVAADPAELGKPVGRDAALGRPNAVGHLG
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHH
IVGAVRRLESLVADAVASVPDCAGAGALRALIHKEAERFLPKELARYAA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDVRQHIDNVLEATMTRADLPDAPPLLAKAMRHAVFPGGGRLRPRLTLAVAAACGNDLPA
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCC
AADAAAAAIELLHCASLVHDDLPCFDDAHSRRGQASVHVAYGEPLAVLAGDALIVMAFQG
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEECCCCHHHHHCCHHHHHHHHH
LASGLAMVPERLPLLLGIVADAVGMPAGICAGQAWESEPTVKLAEYQRAKTGALFAASTM
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
AGAAAAGREARSWRMLGECLGEAYQVADDLRDVAADPAELGKPVGRDAALGRPNAVGHLG
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHH
IVGAVRRLESLVADAVASVPDCAGAGALRALIHKEAERFLPKELARYAA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721699; 10648776 [H]