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The map label for this gene is murA

Identifier: 83594263

GI number: 83594263

Start: 3376464

End: 3377741

Strand: Reverse

Name: murA

Synonym: Rru_A2931

Alternate gene names: 83594263

Gene position: 3377741-3376464 (Counterclockwise)

Preceding gene: 83594264

Following gene: 83594260

Centisome position: 77.6

GC content: 67.61

Gene sequence:

>1278_bases
ATGGACAGGATACGCATTGTCGGCGGCGCTCCGCTTGATGGCACCATCCGGATCGGGGGGGCCAAGAACGCGGCGCTGAC
CTTGATGCCGGTCTGTCTGCTGACCGACCAGCCGGTGACCCTGACCAATCTGCCCGATCTGGCCGATATCCGCACGATGG
CGGCGCTGCTCGGCCAGATGGGGGTGGGGACCTTGCTCAATGGCGCCGAGTCCAGCGCCGGTCGCCATATCGATCTTGAC
GCCTCGGGCCTGTCCGATACCACCGCCCCCTATGATCTGGTGCGCAAGATGCGCGCCTCGATCCTGGTGCTCGGGCCGCT
GGTCGCCCGCCACGGCCGCGCCCGCGTCTCCTTGCCCGGCGGCTGCGCCATCGGCACCCGGCCGGTCGATCTGCACCTCA
AGGCCCTGGAAGCCCTGGGCGCCCATATCGAACTGAAGGAAGGCTATATCCACGCCAGCGTCGAGGGCCGGCTCAAGGGG
GCGAAGATCACCTTCCCCAAGGTCACCGTCGGCGGCACCGAAAACGCCCTGATGGCGGCGACCCTGGCCGAGGGCGAGAC
CCTGCTGGAAAACGTCGCCCGCGAGCCCGAGATCACCGATCTGGCGCTGTGCCTGCGGGCGATGGGGGCGAAGATCGACG
GCATCGGCACCGGAACCCTGCGGGTAGAGGGTGTGGACACGCTGGGCGGGACCAGCCACGCCGTGGTCCCCGATCGCATC
GAAACCGGCACCTATGCCCTGGCGGCGGCGGCGACGCGCGGCCGGCTGACCCTGACGGGAACCCGGCTTGATCTGGTGGA
ATCGCTGGTCGATCACCTGCGCCGCGCCGGAGTCGTGGTCACCGCCATCGAGGGTGGCCTGGAAATCGACGCCCGAACCA
GCGCGTTGACCGGCGTTGACGTGATGACCGAGCCCTTCCCCGGCTTTCCCACCGATATGCAGGCGCAATGGATGGCGGTG
ATGAGCACGGCCCGGGGCGCTTCGATGATCACCGAAAGCATCTTTGAAAACCGCTTCATGCATGTGCCCGAACTGAGCCG
CATGGGCGCCGATATCAATATCCATGGCGGCTCGGCGATCGTGCGCGGCGTCGCCGGCCTGTCGGGCGCCCAGGTGATGG
CCACCGATCTGCGGGCTTCGGTCTGTCTGGTGCTGGCCGCCCTGGCGGCTTCGGGCGAGACCATCATCAACCGGGTCTAT
CATCTCGATCGCGGCTATGAACGGGTGGAGGACAAGCTGGCCGCCTGCGGCGCCACCATCGAACGCCTGCGCGATTAG

Upstream 100 bases:

>100_bases
GCGCGCCGCGCCGTTATGGGATAGGAAACGCCCTTCCGTCGCCGGGCCGCAGAATCAATTCCGCCGGCCCGCTTAGAAAG
TTTGGAAGGTCTTTCCGGTT

Downstream 100 bases:

>100_bases
AAGAGTGGATTTGCTTAACGATTAGACTTTTAGAGCGGTAGGCGGCGCCCCGGTTTCACGCCTGCCGCCTTAAGGGCGCC
GCGCCGCGACAGGAGCGGGC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MDRIRIVGGAPLDGTIRIGGAKNAALTLMPVCLLTDQPVTLTNLPDLADIRTMAALLGQMGVGTLLNGAESSAGRHIDLD
ASGLSDTTAPYDLVRKMRASILVLGPLVARHGRARVSLPGGCAIGTRPVDLHLKALEALGAHIELKEGYIHASVEGRLKG
AKITFPKVTVGGTENALMAATLAEGETLLENVAREPEITDLALCLRAMGAKIDGIGTGTLRVEGVDTLGGTSHAVVPDRI
ETGTYALAAAATRGRLTLTGTRLDLVESLVDHLRRAGVVVTAIEGGLEIDARTSALTGVDVMTEPFPGFPTDMQAQWMAV
MSTARGASMITESIFENRFMHVPELSRMGADINIHGGSAIVRGVAGLSGAQVMATDLRASVCLVLAALAASGETIINRVY
HLDRGYERVEDKLAACGATIERLRD

Sequences:

>Translated_425_residues
MDRIRIVGGAPLDGTIRIGGAKNAALTLMPVCLLTDQPVTLTNLPDLADIRTMAALLGQMGVGTLLNGAESSAGRHIDLD
ASGLSDTTAPYDLVRKMRASILVLGPLVARHGRARVSLPGGCAIGTRPVDLHLKALEALGAHIELKEGYIHASVEGRLKG
AKITFPKVTVGGTENALMAATLAEGETLLENVAREPEITDLALCLRAMGAKIDGIGTGTLRVEGVDTLGGTSHAVVPDRI
ETGTYALAAAATRGRLTLTGTRLDLVESLVDHLRRAGVVVTAIEGGLEIDARTSALTGVDVMTEPFPGFPTDMQAQWMAV
MSTARGASMITESIFENRFMHVPELSRMGADINIHGGSAIVRGVAGLSGAQVMATDLRASVCLVLAALAASGETIINRVY
HLDRGYERVEDKLAACGATIERLRD
>Mature_425_residues
MDRIRIVGGAPLDGTIRIGGAKNAALTLMPVCLLTDQPVTLTNLPDLADIRTMAALLGQMGVGTLLNGAESSAGRHIDLD
ASGLSDTTAPYDLVRKMRASILVLGPLVARHGRARVSLPGGCAIGTRPVDLHLKALEALGAHIELKEGYIHASVEGRLKG
AKITFPKVTVGGTENALMAATLAEGETLLENVAREPEITDLALCLRAMGAKIDGIGTGTLRVEGVDTLGGTSHAVVPDRI
ETGTYALAAAATRGRLTLTGTRLDLVESLVDHLRRAGVVVTAIEGGLEIDARTSALTGVDVMTEPFPGFPTDMQAQWMAV
MSTARGASMITESIFENRFMHVPELSRMGADINIHGGSAIVRGVAGLSGAQVMATDLRASVCLVLAALAASGETIINRVY
HLDRGYERVEDKLAACGATIERLRD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=424, Percent_Identity=52.122641509434, Blast_Score=425, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_RHORT (Q2RQ67)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428015.1
- ProteinModelPortal:   Q2RQ67
- SMR:   Q2RQ67
- STRING:   Q2RQ67
- GeneID:   3836372
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A2931
- NMPDR:   fig|1085.1.peg.574
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q2RQ67
- ProtClustDB:   PRK09369
- BioCyc:   RRUB269796:RRU_A2931-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44474; Mature: 44474

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: ACT_SITE 122-122

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIVGGAPLDGTIRIGGAKNAALTLMPVCLLTDQPVTLTNLPDLADIRTMAALLGQM
CCCEEEEECCCCCCEEEECCCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHC
GVGTLLNGAESSAGRHIDLDASGLSDTTAPYDLVRKMRASILVLGPLVARHGRARVSLPG
CHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHEEEEHHHHHCCCCEEEECCC
GCAIGTRPVDLHLKALEALGAHIELKEGYIHASVEGRLKGAKITFPKVTVGGTENALMAA
CCEECCCCHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCCEEECCEEEECCCCCCEEEE
TLAEGETLLENVAREPEITDLALCLRAMGAKIDGIGTGTLRVEGVDTLGGTSHAVVPDRI
EHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
ETGTYALAAAATRGRLTLTGTRLDLVESLVDHLRRAGVVVTAIEGGLEIDARTSALTGVD
CCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCEEEEEECCCEEECCCCCCCCCCH
VMTEPFPGFPTDMQAQWMAVMSTARGASMITESIFENRFMHVPELSRMGADINIHGGSAI
HCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCCCCEEECCCHHH
VRGVAGLSGAQVMATDLRASVCLVLAALAASGETIINRVYHLDRGYERVEDKLAACGATI
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ERLRD
HHHCC
>Mature Secondary Structure
MDRIRIVGGAPLDGTIRIGGAKNAALTLMPVCLLTDQPVTLTNLPDLADIRTMAALLGQM
CCCEEEEECCCCCCEEEECCCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHC
GVGTLLNGAESSAGRHIDLDASGLSDTTAPYDLVRKMRASILVLGPLVARHGRARVSLPG
CHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHEEEEHHHHHCCCCEEEECCC
GCAIGTRPVDLHLKALEALGAHIELKEGYIHASVEGRLKGAKITFPKVTVGGTENALMAA
CCEECCCCHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCCEEECCEEEECCCCCCEEEE
TLAEGETLLENVAREPEITDLALCLRAMGAKIDGIGTGTLRVEGVDTLGGTSHAVVPDRI
EHHCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
ETGTYALAAAATRGRLTLTGTRLDLVESLVDHLRRAGVVVTAIEGGLEIDARTSALTGVD
CCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCEEEEEECCCEEECCCCCCCCCCH
VMTEPFPGFPTDMQAQWMAVMSTARGASMITESIFENRFMHVPELSRMGADINIHGGSAI
HCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHCCCCEEECCCHHH
VRGVAGLSGAQVMATDLRASVCLVLAALAASGETIINRVYHLDRGYERVEDKLAACGATI
HHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
ERLRD
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA