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The map label for this gene is lrp [H]

Identifier: 83594228

GI number: 83594228

Start: 3338974

End: 3339468

Strand: Reverse

Name: lrp [H]

Synonym: Rru_A2896

Alternate gene names: 83594228

Gene position: 3339468-3338974 (Counterclockwise)

Preceding gene: 83594232

Following gene: 83594227

Centisome position: 76.72

GC content: 64.85

Gene sequence:

>495_bases
ATGGCGACACAGCGCGTTAAGCTGGACCGCATCGACCGCAGGATTCTCAACGATCTCCAGAGCGACGGCCGGATGACCAA
CGTCGATCTGGCCAAGCGGGCGGGCATCTCGGCGCCCCCGTGTTTGCGCCGCGTTCGCGCGCTCGAGGAGGCCGGGTTCA
TCCGGGGCTATCACGCCGATCTCGACGCGGTGTCGCTGGGCTATAATGTGACGGTTTTCGCCCATGTCGGCCTGAATAGT
CAGGCCGAATCCGATCTGCGCGCCTTCGAGGATCTGGTGGCGAGCTGGCCCGAGGTGCGCGAATGCCACATGCTGGCCGG
CGAGACCGATTTCCTGCTGAAGGTGGTGGCGCGCGACTGGGATGATTACCAGCGCTTCCTGACCTCGCGTCTGACCCCGG
CGCCCAATGTCGGCCATGTGAAATCCGCCCTGGCCATTCGCACCGGCAAGCTGCAACCCGGCGTTCCCGTTGCCGAGACC
GATCCCGACGACTAA

Upstream 100 bases:

>100_bases
GCCGTGGGGCAAGGGGTATTCTCGTTGCGCGGTCCGGGTGATTACGTGTAATTTCCTTTCTCGTATCGACCGACACCGAT
AGCTTGAAGGCAGGGTTTTC

Downstream 100 bases:

>100_bases
GTTTTCTCGCCGGCCCCGCGTCGGCGAAGCCAAAAATGGACGCTGGCGGAACGGGGAACGGTCCTTATCTTCTGTGTAAA
TCCATGCGGGAGGGGGCGAT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MATQRVKLDRIDRRILNDLQSDGRMTNVDLAKRAGISAPPCLRRVRALEEAGFIRGYHADLDAVSLGYNVTVFAHVGLNS
QAESDLRAFEDLVASWPEVRECHMLAGETDFLLKVVARDWDDYQRFLTSRLTPAPNVGHVKSALAIRTGKLQPGVPVAET
DPDD

Sequences:

>Translated_164_residues
MATQRVKLDRIDRRILNDLQSDGRMTNVDLAKRAGISAPPCLRRVRALEEAGFIRGYHADLDAVSLGYNVTVFAHVGLNS
QAESDLRAFEDLVASWPEVRECHMLAGETDFLLKVVARDWDDYQRFLTSRLTPAPNVGHVKSALAIRTGKLQPGVPVAET
DPDD
>Mature_163_residues
ATQRVKLDRIDRRILNDLQSDGRMTNVDLAKRAGISAPPCLRRVRALEEAGFIRGYHADLDAVSLGYNVTVFAHVGLNSQ
AESDLRAFEDLVASWPEVRECHMLAGETDFLLKVVARDWDDYQRFLTSRLTPAPNVGHVKSALAIRTGKLQPGVPVAETD
PDD

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=41.958041958042, Blast_Score=119, Evalue=8e-29,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=29.3333333333333, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1790182, Length=124, Percent_Identity=29.8387096774194, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18212; Mature: 18081

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQRVKLDRIDRRILNDLQSDGRMTNVDLAKRAGISAPPCLRRVRALEEAGFIRGYHAD
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCC
LDAVSLGYNVTVFAHVGLNSQAESDLRAFEDLVASWPEVRECHMLAGETDFLLKVVARDW
CCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCH
DDYQRFLTSRLTPAPNVGHVKSALAIRTGKLQPGVPVAETDPDD
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATQRVKLDRIDRRILNDLQSDGRMTNVDLAKRAGISAPPCLRRVRALEEAGFIRGYHAD
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCC
LDAVSLGYNVTVFAHVGLNSQAESDLRAFEDLVASWPEVRECHMLAGETDFLLKVVARDW
CCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCH
DDYQRFLTSRLTPAPNVGHVKSALAIRTGKLQPGVPVAETDPDD
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]