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The map label for this gene is carA [H]

Identifier: 83594217

GI number: 83594217

Start: 3327494

End: 3328663

Strand: Direct

Name: carA [H]

Synonym: Rru_A2885

Alternate gene names: 83594217

Gene position: 3327494-3328663 (Clockwise)

Preceding gene: 83594213

Following gene: 83594218

Centisome position: 76.44

GC content: 66.5

Gene sequence:

>1170_bases
ATGTCCACGCCCTCGCACACTCCCAAGCCCCCCGGGGCCACGGCCGTTCTGGCGCTTGCCGATGGCACGCTCTTCTGGGG
CCGAGGCGTGGGCGCCTTGGGCGAAGTGGTCGGCGAGGTCTGCTTCAACACGGCGATGACCGGCTATCAGGAAGTGATGA
CCGATCCGTCCTATGCCGGGCAGATCGTCACCTTCTGCTTTCCCCATATCGGCAATGTCGGCACCAACGCCGAGGATATC
GAAAGCACCGTCCCCGCCGCCCGCGGTTGCGTGCTGCGCGCCGACATCACCGAACCGGCCAATTGGCGGGCCACCGGCGC
CTTGAACGGCTGGCTGGCGGCGCGCGGCCTTGTCGGCATCAGCGGCGTCGATACCCGCCAGCTGACCCGGCGCATCCGCG
ACCTTGGCGCCCCCAGCGGGGTGATCGCCCATGCCGCCGACGGCGTTTTCGACATCCCCGCCCTGGTGGCCAAGGCGCAA
GGCTGGCCCGGGCTCGAGGGCATGGATCTCGCCGCCGAGGTCACCTGCACCCAGACCTACGCCTGGGACGAGACCCTGTG
GTCGCTGGACGGCGGCTATGGACGGTTGAGCGATCCTCGCTTCCATGTGGTGGCCATCGACTACGGCGCCAAGCGCAATA
TCTTGCGCAATCTGGCCTCGCTGGGCTGCAAGGTCACCGTCGTGCCGGCCCAGACCACCCTTGACGAGGTGATGGCCCAT
CAGCCCGACGGCATCTTCCTGTCGAACGGCCCGGGCGACCCGGCGGCCACCGGAACCTATGCGGTGCCGGTGATCAAACA
GCTGATCGAGACCGGCAAGCCGCTGTTTGGCATTTGCCTGGGCCATCAGATGCTGGCCCTGGCCCTGGGGGCGACGACCT
ATAAGATGGCCACCGGCCATCGCGGGGCCAACCACCCGGTGAAGGATCACACCACCGGCAAGGTCGAAATCACCTCGATG
AACCATGGCTTTGCCGTGGATCGGGCCAGCCTGCCCGCCGGCGTCACCGAAACCCACACCAGTTTGTTTGACAATGTCCT
TGAAGGGCTGGCCGTCGATGGCAAGCCGGTGTTTTCGGTGCAATACCACCCGGAAGCCTCGCCCGGCCCCGAGGACAGCC
ACTATCTGTTCAAGCGCTTCGTCGATCTGATGGACGCCCGCCGCGTCTGA

Upstream 100 bases:

>100_bases
CCTAACCCTGACCGCCTTCCCCCGATCGCCCGAGCCTCCGCTCGCGCGGTGCTTCCGGAGAGGGCGGATCGCGCCCTTTA
GGATCCGGGGAACCATCGCC

Downstream 100 bases:

>100_bases
ACACGTCGTCCTTCGCGTCCTTCGTCAGCGCCGCCGCCGCCGGCACGCTCGCCTCCCCGTCTGGTCGCCTTCCCGAGGAA
CCCCATGCCCAAACGCACGG

Product: carbamoyl-phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MSTPSHTPKPPGATAVLALADGTLFWGRGVGALGEVVGEVCFNTAMTGYQEVMTDPSYAGQIVTFCFPHIGNVGTNAEDI
ESTVPAARGCVLRADITEPANWRATGALNGWLAARGLVGISGVDTRQLTRRIRDLGAPSGVIAHAADGVFDIPALVAKAQ
GWPGLEGMDLAAEVTCTQTYAWDETLWSLDGGYGRLSDPRFHVVAIDYGAKRNILRNLASLGCKVTVVPAQTTLDEVMAH
QPDGIFLSNGPGDPAATGTYAVPVIKQLIETGKPLFGICLGHQMLALALGATTYKMATGHRGANHPVKDHTTGKVEITSM
NHGFAVDRASLPAGVTETHTSLFDNVLEGLAVDGKPVFSVQYHPEASPGPEDSHYLFKRFVDLMDARRV

Sequences:

>Translated_389_residues
MSTPSHTPKPPGATAVLALADGTLFWGRGVGALGEVVGEVCFNTAMTGYQEVMTDPSYAGQIVTFCFPHIGNVGTNAEDI
ESTVPAARGCVLRADITEPANWRATGALNGWLAARGLVGISGVDTRQLTRRIRDLGAPSGVIAHAADGVFDIPALVAKAQ
GWPGLEGMDLAAEVTCTQTYAWDETLWSLDGGYGRLSDPRFHVVAIDYGAKRNILRNLASLGCKVTVVPAQTTLDEVMAH
QPDGIFLSNGPGDPAATGTYAVPVIKQLIETGKPLFGICLGHQMLALALGATTYKMATGHRGANHPVKDHTTGKVEITSM
NHGFAVDRASLPAGVTETHTSLFDNVLEGLAVDGKPVFSVQYHPEASPGPEDSHYLFKRFVDLMDARRV
>Mature_388_residues
STPSHTPKPPGATAVLALADGTLFWGRGVGALGEVVGEVCFNTAMTGYQEVMTDPSYAGQIVTFCFPHIGNVGTNAEDIE
STVPAARGCVLRADITEPANWRATGALNGWLAARGLVGISGVDTRQLTRRIRDLGAPSGVIAHAADGVFDIPALVAKAQG
WPGLEGMDLAAEVTCTQTYAWDETLWSLDGGYGRLSDPRFHVVAIDYGAKRNILRNLASLGCKVTVVPAQTTLDEVMAHQ
PDGIFLSNGPGDPAATGTYAVPVIKQLIETGKPLFGICLGHQMLALALGATTYKMATGHRGANHPVKDHTTGKVEITSMN
HGFAVDRASLPAGVTETHTSLFDNVLEGLAVDGKPVFSVQYHPEASPGPEDSHYLFKRFVDLMDARRV

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=378, Percent_Identity=37.8306878306878, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI21361331, Length=387, Percent_Identity=36.9509043927649, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI169790915, Length=387, Percent_Identity=36.9509043927649, Blast_Score=202, Evalue=4e-52,
Organism=Escherichia coli, GI1786215, Length=378, Percent_Identity=53.1746031746032, Blast_Score=391, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI193204318, Length=380, Percent_Identity=37.1052631578947, Blast_Score=229, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6324878, Length=391, Percent_Identity=36.8286445012788, Blast_Score=216, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6322331, Length=395, Percent_Identity=33.6708860759494, Blast_Score=210, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24642586, Length=389, Percent_Identity=35.9897172236504, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI45555749, Length=389, Percent_Identity=35.9897172236504, Blast_Score=219, Evalue=4e-57,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 41142; Mature: 41011

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPSHTPKPPGATAVLALADGTLFWGRGVGALGEVVGEVCFNTAMTGYQEVMTDPSYAG
CCCCCCCCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QIVTFCFPHIGNVGTNAEDIESTVPAARGCVLRADITEPANWRATGALNGWLAARGLVGI
HHHHHHHHHCCCCCCCHHHHHHHCHHHHCEEEEECCCCCCCCEECCCCCHHHHHCCCCCC
SGVDTRQLTRRIRDLGAPSGVIAHAADGVFDIPALVAKAQGWPGLEGMDLAAEVTCTQTY
CCCCHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEE
AWDETLWSLDGGYGRLSDPRFHVVAIDYGAKRNILRNLASLGCKVTVVPAQTTLDEVMAH
ECCHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHC
QPDGIFLSNGPGDPAATGTYAVPVIKQLIETGKPLFGICLGHQMLALALGATTYKMATGH
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCHHEEEECCC
RGANHPVKDHTTGKVEITSMNHGFAVDRASLPAGVTETHTSLFDNVLEGLAVDGKPVFSV
CCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
QYHPEASPGPEDSHYLFKRFVDLMDARRV
EECCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPSHTPKPPGATAVLALADGTLFWGRGVGALGEVVGEVCFNTAMTGYQEVMTDPSYAG
CCCCCCCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QIVTFCFPHIGNVGTNAEDIESTVPAARGCVLRADITEPANWRATGALNGWLAARGLVGI
HHHHHHHHHCCCCCCCHHHHHHHCHHHHCEEEEECCCCCCCCEECCCCCHHHHHCCCCCC
SGVDTRQLTRRIRDLGAPSGVIAHAADGVFDIPALVAKAQGWPGLEGMDLAAEVTCTQTY
CCCCHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEE
AWDETLWSLDGGYGRLSDPRFHVVAIDYGAKRNILRNLASLGCKVTVVPAQTTLDEVMAH
ECCHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHCCCEEEEEECHHHHHHHHHC
QPDGIFLSNGPGDPAATGTYAVPVIKQLIETGKPLFGICLGHQMLALALGATTYKMATGH
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCHHEEEECCC
RGANHPVKDHTTGKVEITSMNHGFAVDRASLPAGVTETHTSLFDNVLEGLAVDGKPVFSV
CCCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEE
QYHPEASPGPEDSHYLFKRFVDLMDARRV
EECCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]