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The map label for this gene is codA [H]

Identifier: 83594120

GI number: 83594120

Start: 3222171

End: 3223493

Strand: Direct

Name: codA [H]

Synonym: Rru_A2788

Alternate gene names: 83594120

Gene position: 3222171-3223493 (Clockwise)

Preceding gene: 83594119

Following gene: 83594122

Centisome position: 74.02

GC content: 68.1

Gene sequence:

>1323_bases
ATGACCACTTTTCCCCCCGCCCAGGACTTGATCGTCCGCAACGCCAGCCTGCCCGATGGCCGCCGCGCTCAGGACATCCT
GATCCTGGCGGGCACGATCAAAGCCATCGGCCCGGCCCTGGACGCGCCCGAGGCCACCCCGGTTCTTGACGCCAAAGGCG
ATCTGGTCGCCCCGCCCTTCGTCGATGCCCATTTCCATATGGACTCGGCACTGTCTTACGGCCTGCCGCGGATCAACGCC
TCGGGCACCTTGCTCGAAGGCATCGCCCTGTGGGGGGAACTCAAGCCCGAGTTGACCCATCAGGCGATTGTTGATCGGGC
GCTTGCCTATTGCGACTGGGCGATCGGTCGCGGCCTGCTGGCCATCCGCAGCCATGTCGATATCTGCGATCCCCGCCTGC
TCGCCGTCGACGCCCTGCTCGAAGTCCGCGAAAAAGTCGCCCCCTGGCTGACCTTGCAGCTTGTCGCCTTCCCCCAGGAT
GGCTTCTTGCGCGCCCAAGGCAGCCGCGAGCGCCTGATCGCCGCCCTGGATCGCGGCGTCGATGTGGTCGGCGGCATCCC
GCATTTCGAACGCACGATGGCTCAAGGCGCCGAAAGCGTGCGCGCGCTGTGCGAGATCGCCGCCGAGCGCGGCTTGCGCG
TGGATATGCATTGCGATGAAAGCGACGACCCGATGAGCCGCCACGTCGAGACCCTGGCGGCGGAAACCACCCGCCTCGGT
CTGGAAGGACGGGTCACCGGCTCGCACCTGACCTCGATGCATTCGATGGACAGCTACTACGTCTCGAAACTGATCGCCCT
GATGGCCGAGGCCGAGCTGGGGGTGATCGCCAATCCGCTGATCAACATCACCCTTCAGGGCCGCCACGACGGCTATCCCA
AGCGCCGGGGGATGACCCGGGTGCCCGAATTGCTCGCCGCCGGTCTGACCGTGGCCTTCGGCCATGACTGCGTGATGGAC
CCCTGGTATGGCCTGGGCAGCGCCGACATGCTTGAAGTCGCCGCCATGGGCCTTCACGTCGCCCAGATGACCGGCCAGTC
GGCGATGGCCGAGTGCTTCGCCGCCGTCACCACGGCGCCGGCCAAGCTGATGGGGCTCGACGATTACGGCCTGATGCCCG
GCTGTCGGGGCGATCTGGTGCTGCTGCAGGCCGGCGATCCGGTGGAGGCCCTGCGTCTGCGCGCGACCCGGCTGGCCGTG
GTGCGCGGCGGCCGGATCATCGCCCGCACCCCGGCGGCCACCGCCACCTTGGATCTGGGCGACGGCGACCGCCCCACCCT
AAACCCGGTGTCCTGGCGTGGCGGCGAGCGCCCGGGGTTCTAA

Upstream 100 bases:

>100_bases
GCCCCCTATGTGCTGAGCATCGTCGCCCTGGTCGTCATGTCGCGCCGCGCCGCCTATCCCCAGGCCCTGATGATCCCCTT
CCGCAAGGGAGAACGCTAAG

Downstream 100 bases:

>100_bases
GGCAGTCTCCCCGGCCTCGCCTTCCCCCGCCGAACTCGGAACCAGTTCGACCAGCCGTCCGGCCTCGCGGCCGACGATAT
CGGCCACCGAGCCGTGCAAC

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MTTFPPAQDLIVRNASLPDGRRAQDILILAGTIKAIGPALDAPEATPVLDAKGDLVAPPFVDAHFHMDSALSYGLPRINA
SGTLLEGIALWGELKPELTHQAIVDRALAYCDWAIGRGLLAIRSHVDICDPRLLAVDALLEVREKVAPWLTLQLVAFPQD
GFLRAQGSRERLIAALDRGVDVVGGIPHFERTMAQGAESVRALCEIAAERGLRVDMHCDESDDPMSRHVETLAAETTRLG
LEGRVTGSHLTSMHSMDSYYVSKLIALMAEAELGVIANPLINITLQGRHDGYPKRRGMTRVPELLAAGLTVAFGHDCVMD
PWYGLGSADMLEVAAMGLHVAQMTGQSAMAECFAAVTTAPAKLMGLDDYGLMPGCRGDLVLLQAGDPVEALRLRATRLAV
VRGGRIIARTPAATATLDLGDGDRPTLNPVSWRGGERPGF

Sequences:

>Translated_440_residues
MTTFPPAQDLIVRNASLPDGRRAQDILILAGTIKAIGPALDAPEATPVLDAKGDLVAPPFVDAHFHMDSALSYGLPRINA
SGTLLEGIALWGELKPELTHQAIVDRALAYCDWAIGRGLLAIRSHVDICDPRLLAVDALLEVREKVAPWLTLQLVAFPQD
GFLRAQGSRERLIAALDRGVDVVGGIPHFERTMAQGAESVRALCEIAAERGLRVDMHCDESDDPMSRHVETLAAETTRLG
LEGRVTGSHLTSMHSMDSYYVSKLIALMAEAELGVIANPLINITLQGRHDGYPKRRGMTRVPELLAAGLTVAFGHDCVMD
PWYGLGSADMLEVAAMGLHVAQMTGQSAMAECFAAVTTAPAKLMGLDDYGLMPGCRGDLVLLQAGDPVEALRLRATRLAV
VRGGRIIARTPAATATLDLGDGDRPTLNPVSWRGGERPGF
>Mature_439_residues
TTFPPAQDLIVRNASLPDGRRAQDILILAGTIKAIGPALDAPEATPVLDAKGDLVAPPFVDAHFHMDSALSYGLPRINAS
GTLLEGIALWGELKPELTHQAIVDRALAYCDWAIGRGLLAIRSHVDICDPRLLAVDALLEVREKVAPWLTLQLVAFPQDG
FLRAQGSRERLIAALDRGVDVVGGIPHFERTMAQGAESVRALCEIAAERGLRVDMHCDESDDPMSRHVETLAAETTRLGL
EGRVTGSHLTSMHSMDSYYVSKLIALMAEAELGVIANPLINITLQGRHDGYPKRRGMTRVPELLAAGLTVAFGHDCVMDP
WYGLGSADMLEVAAMGLHVAQMTGQSAMAECFAAVTTAPAKLMGLDDYGLMPGCRGDLVLLQAGDPVEALRLRATRLAVV
RGGRIIARTPAATATLDLGDGDRPTLNPVSWRGGERPGF

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=407, Percent_Identity=44.7174447174447, Blast_Score=345, Evalue=3e-96,
Organism=Escherichia coli, GI1786517, Length=407, Percent_Identity=26.5356265356265, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47119; Mature: 46988

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFPPAQDLIVRNASLPDGRRAQDILILAGTIKAIGPALDAPEATPVLDAKGDLVAPPF
CCCCCCCHHHHEECCCCCCCCCCCEEEEEECHHHHHCCCCCCCCCCCEECCCCCCCCCCC
VDAHFHMDSALSYGLPRINASGTLLEGIALWGELKPELTHQAIVDRALAYCDWAIGRGLL
CCHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHH
AIRSHVDICDPRLLAVDALLEVREKVAPWLTLQLVAFPQDGFLRAQGSRERLIAALDRGV
HHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCEECCCCHHHHHHHHHCCC
DVVGGIPHFERTMAQGAESVRALCEIAAERGLRVDMHCDESDDPMSRHVETLAAETTRLG
CEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCC
LEGRVTGSHLTSMHSMDSYYVSKLIALMAEAELGVIANPLINITLQGRHDGYPKRRGMTR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCCHH
VPELLAAGLTVAFGHDCVMDPWYGLGSADMLEVAAMGLHVAQMTGQSAMAECFAAVTTAP
HHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
AKLMGLDDYGLMPGCRGDLVLLQAGDPVEALRLRATRLAVVRGGRIIARTPAATATLDLG
HHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEEECCEEEEECCCCEEEEECC
DGDRPTLNPVSWRGGERPGF
CCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTFPPAQDLIVRNASLPDGRRAQDILILAGTIKAIGPALDAPEATPVLDAKGDLVAPPF
CCCCCCHHHHEECCCCCCCCCCCEEEEEECHHHHHCCCCCCCCCCCEECCCCCCCCCCC
VDAHFHMDSALSYGLPRINASGTLLEGIALWGELKPELTHQAIVDRALAYCDWAIGRGLL
CCHHHCHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHH
AIRSHVDICDPRLLAVDALLEVREKVAPWLTLQLVAFPQDGFLRAQGSRERLIAALDRGV
HHHHCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCEECCCCHHHHHHHHHCCC
DVVGGIPHFERTMAQGAESVRALCEIAAERGLRVDMHCDESDDPMSRHVETLAAETTRLG
CEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHCC
LEGRVTGSHLTSMHSMDSYYVSKLIALMAEAELGVIANPLINITLQGRHDGYPKRRGMTR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCCHH
VPELLAAGLTVAFGHDCVMDPWYGLGSADMLEVAAMGLHVAQMTGQSAMAECFAAVTTAP
HHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
AKLMGLDDYGLMPGCRGDLVLLQAGDPVEALRLRATRLAVVRGGRIIARTPAATATLDLG
HHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEEECCEEEEECCCCEEEEECC
DGDRPTLNPVSWRGGERPGF
CCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]