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The map label for this gene is oxyR [H]

Identifier: 83594114

GI number: 83594114

Start: 3215711

End: 3216616

Strand: Reverse

Name: oxyR [H]

Synonym: Rru_A2782

Alternate gene names: 83594114

Gene position: 3216616-3215711 (Counterclockwise)

Preceding gene: 83594121

Following gene: 83594113

Centisome position: 73.9

GC content: 66.56

Gene sequence:

>906_bases
ATGTTCACGTTGCGCCAACTCCGCTACATCGTCGCCGTAGCCGATACCCTGAATTTCCGCCGTGCCGCCGAGGTTTGTCT
GGTGTCGCAACCCACGCTCAGCGTGCAGATCGCCGAGGTCGAAGCCTTCCTTGGGCTGACGCTGTTCGAGCGCACTCGCC
GCAGCGTGGTGCTGACGCCGATCGGCCGCGAAATCGCCGAACGGGCGCGCGGCGTTCTGCGCGAGGCCAATGAGATCGTC
GATCTGGCGCGCTCGCTGCGCGCTCCCCTGTCGGGGCCGCTGCGTCTGGGCGTCATCGCCACCCTCGGCCCCTATCTGCT
GCCCTATGTGTTGTCGGCCTTCCGCGAAAAGCATCCCTCCTTGCGCCTTTACCTGCGCGAGGACCCATCGCTGCGCCTAG
AGCGTCGGCTGCGGGCCGGTGAGCTTGATCTGATCCTGGTCGATATGCCCATCGACGATGCCGGCCTCGACATCATGGAT
CTGTTTTTCGAGCCCCTATGGCTGGCCGCGCCCCCCGATCACGCCCTGGCCGACAGGACGCGGGTGAGCGTCGAGGATCT
CGCCGGGCGCGACCTTTTGCTGCTCGAAGAGGGCCATTGCCTGCGCGACGAGGTGCTTGACCTCTGCCGGCGGGTGGGGG
CGCGCGAACATGGCGGCTTCCAGGCGACCAGCCTTGACACCCTGCGTCAGATGGTGGCCAGCCGCATCGGTCTGGCCCTG
CTGCCCGATCTGTATGTCGCCGCCGAGGCCGCCCAGGATCCCAATATCCGGATGATTCCCTTCAGCGCGCCGCCGGTCCG
CCGAGTCGGTTTGGCATGGCGCAAAACCTCGGCGCGCGTAGCCGAATTTCGCGAATTCGGCGCCTTTATCCTGGCCCGGT
TGCCGGCCAGTCTCGCGGTTCCGTGA

Upstream 100 bases:

>100_bases
TGACCCTTGATATAGCCCCCTTGAAAGATAGGTTCCAATTGATACCAAGGCATCCTGTGATAGGGTGAAATTATCATTAA
AGCCGCTTTCGGAGCCGTCG

Downstream 100 bases:

>100_bases
GGAAATCGGCTTCCCGCAAATTGCCTTGTTTCCCATGGGTTAATCGGGCTCTCTTAGATTAATTCATCTAACCGCCAAGA
CGATTATTCCTCGCCCTGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MFTLRQLRYIVAVADTLNFRRAAEVCLVSQPTLSVQIAEVEAFLGLTLFERTRRSVVLTPIGREIAERARGVLREANEIV
DLARSLRAPLSGPLRLGVIATLGPYLLPYVLSAFREKHPSLRLYLREDPSLRLERRLRAGELDLILVDMPIDDAGLDIMD
LFFEPLWLAAPPDHALADRTRVSVEDLAGRDLLLLEEGHCLRDEVLDLCRRVGAREHGGFQATSLDTLRQMVASRIGLAL
LPDLYVAAEAAQDPNIRMIPFSAPPVRRVGLAWRKTSARVAEFREFGAFILARLPASLAVP

Sequences:

>Translated_301_residues
MFTLRQLRYIVAVADTLNFRRAAEVCLVSQPTLSVQIAEVEAFLGLTLFERTRRSVVLTPIGREIAERARGVLREANEIV
DLARSLRAPLSGPLRLGVIATLGPYLLPYVLSAFREKHPSLRLYLREDPSLRLERRLRAGELDLILVDMPIDDAGLDIMD
LFFEPLWLAAPPDHALADRTRVSVEDLAGRDLLLLEEGHCLRDEVLDLCRRVGAREHGGFQATSLDTLRQMVASRIGLAL
LPDLYVAAEAAQDPNIRMIPFSAPPVRRVGLAWRKTSARVAEFREFGAFILARLPASLAVP
>Mature_301_residues
MFTLRQLRYIVAVADTLNFRRAAEVCLVSQPTLSVQIAEVEAFLGLTLFERTRRSVVLTPIGREIAERARGVLREANEIV
DLARSLRAPLSGPLRLGVIATLGPYLLPYVLSAFREKHPSLRLYLREDPSLRLERRLRAGELDLILVDMPIDDAGLDIMD
LFFEPLWLAAPPDHALADRTRVSVEDLAGRDLLLLEEGHCLRDEVLDLCRRVGAREHGGFQATSLDTLRQMVASRIGLAL
LPDLYVAAEAAQDPNIRMIPFSAPPVRRVGLAWRKTSARVAEFREFGAFILARLPASLAVP

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=40.6143344709898, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI157672245, Length=290, Percent_Identity=30.3448275862069, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=30.3333333333333, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787879, Length=296, Percent_Identity=30.0675675675676, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787530, Length=261, Percent_Identity=29.5019157088123, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=29.2181069958848, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI145693105, Length=273, Percent_Identity=26.3736263736264, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=29.6747967479675, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=31.1740890688259, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790262, Length=251, Percent_Identity=26.6932270916335, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=31.4685314685315, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789204, Length=285, Percent_Identity=25.9649122807018, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=27.9835390946502, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788481, Length=206, Percent_Identity=28.1553398058252, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081904, Length=178, Percent_Identity=33.1460674157303, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=245, Percent_Identity=28.1632653061224, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33587; Mature: 33587

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTLRQLRYIVAVADTLNFRRAAEVCLVSQPTLSVQIAEVEAFLGLTLFERTRRSVVLTP
CCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHCCEEEECC
IGREIAERARGVLREANEIVDLARSLRAPLSGPLRLGVIATLGPYLLPYVLSAFREKHPS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
LRLYLREDPSLRLERRLRAGELDLILVDMPIDDAGLDIMDLFFEPLWLAAPPDHALADRT
EEEEEECCCCHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHCCCEECCCCCHHHHHHH
RVSVEDLAGRDLLLLEEGHCLRDEVLDLCRRVGAREHGGFQATSLDTLRQMVASRIGLAL
CCCHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHH
LPDLYVAAEAAQDPNIRMIPFSAPPVRRVGLAWRKTSARVAEFREFGAFILARLPASLAV
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
P
C
>Mature Secondary Structure
MFTLRQLRYIVAVADTLNFRRAAEVCLVSQPTLSVQIAEVEAFLGLTLFERTRRSVVLTP
CCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHCCEEEECC
IGREIAERARGVLREANEIVDLARSLRAPLSGPLRLGVIATLGPYLLPYVLSAFREKHPS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
LRLYLREDPSLRLERRLRAGELDLILVDMPIDDAGLDIMDLFFEPLWLAAPPDHALADRT
EEEEEECCCCHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHCCCEECCCCCHHHHHHH
RVSVEDLAGRDLLLLEEGHCLRDEVLDLCRRVGAREHGGFQATSLDTLRQMVASRIGLAL
CCCHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHH
LPDLYVAAEAAQDPNIRMIPFSAPPVRRVGLAWRKTSARVAEFREFGAFILARLPASLAV
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]