Click here to switch to the map view.

The map label for this gene is mdmB [H]

Identifier: 83594093

GI number: 83594093

Start: 3193350

End: 3194507

Strand: Reverse

Name: mdmB [H]

Synonym: Rru_A2761

Alternate gene names: 83594093

Gene position: 3194507-3193350 (Counterclockwise)

Preceding gene: 83594094

Following gene: 83594092

Centisome position: 73.39

GC content: 37.31

Gene sequence:

>1158_bases
TTGACTTATTCAGTGAGTGCTACTGGTGATAAATCCGGAGTTTTTTTAAAATCTTTGACTGGAATTAGGTTGTTTGCGGC
TTTGGCGATCGTGCTTCATCACGTGCCGGGACACTTTGGAATCTCCCACGAGCTGACAGAGGGGTGGAGCTTAGGTCAGG
GGGTTTCGGTTTTCTTTGTGTTGTCCGGTTTTATTTTGACTTACCGATATCCTGCTTTGACTGATCGGGCCGCCATAGTG
CGGTTTTGGGTTGCGCGCGTGGCAAGAATATGGCCGGCGCATGCCTTTATTTTGTTTGTTCTTTTGCTCGTAAATTACGA
TTCTATGCCTGATATTGAAAGTACAAGTCTAAAAAATATTCTGGCGAATGTGTTTTTAGTTCAGTCTTGGTTTCCATATG
CTGGGTATTTTTTTGGATATAATAGCGTAAGTTGGAGCATATCTACGGAAATGGGATTTTATTTGCTGTTTCCGTTTTTG
ATATTTTGTTTTCAAAAAACATGGTTGTTGAAAGTTTTCATTTCTTTTTCTGTCGGTTTTGTTTTTGTGTTGTTGGCTTA
TTATATGAGCATTCCAAGTTTTCAGTATCCAGATAATAAGATTGTTATGGAGGGGTTGATTTATGTCAATCCGCTTGCAA
GGCTATTTGAGTTTGTTGCTGGAATGTGTTCCGCATTTTTGTGGATAAAATTTCATAATCGTATAGTTATGAATAGAGTG
CTCTGGACTGTACTAGAAGTGTTTTCGGTTTTGTTTCTTATTTTTAATGTGAGTTTTCTGTCTAAAATTTTTTCTGTTTT
TAGTTTTGATTTTGGATTTCCTGGTTTGTACTGGAAAGTTATGAGCTTATTTCCGGCTCTGGCTGCGGCTGTTTTTATTT
TTGTAATGGCAAAAAGTGAAGGTTTCCTCTCTTCTGTTTTATCAACAAGATTTTTTGTTTACATGGGAGAGGTTTCTTTC
TCAATTTACCTTCTTCATCTTGTGATTATAAAAATGTTTGATGATCTGCCGGCACTTGGGTATCTCAACGATTTTTTCGC
TTTAATTTTGGCGCTTATCTCTGTGTTTGTTTGCTCTATGTTAATGTTCCATTTTGTAGAAAAGCCAGGAAAGACCATGA
TTATTTCTGTGTCTCGTCTTTTTGGAAATCGTAAATAG

Upstream 100 bases:

>100_bases
CGATCCCTTTCTGTGAAAGTCGTGAAGCTTATCATTTTGTCTTAGATTAAAATGTTCGCCGAGTTTTTAGAAAAAACACA
TCTTCCCTGGGGAACGCGCT

Downstream 100 bases:

>100_bases
AAAGCAAGAAGGTCTTTTTTATTTTTTTGATTTCTTGAGTTTTGTTCCGGTCGCATCCTTTTTTTAAAAAAAGGGATCGC
TGATCTTCATCGCTTTCAAA

Product: acyltransferase 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MTYSVSATGDKSGVFLKSLTGIRLFAALAIVLHHVPGHFGISHELTEGWSLGQGVSVFFVLSGFILTYRYPALTDRAAIV
RFWVARVARIWPAHAFILFVLLLVNYDSMPDIESTSLKNILANVFLVQSWFPYAGYFFGYNSVSWSISTEMGFYLLFPFL
IFCFQKTWLLKVFISFSVGFVFVLLAYYMSIPSFQYPDNKIVMEGLIYVNPLARLFEFVAGMCSAFLWIKFHNRIVMNRV
LWTVLEVFSVLFLIFNVSFLSKIFSVFSFDFGFPGLYWKVMSLFPALAAAVFIFVMAKSEGFLSSVLSTRFFVYMGEVSF
SIYLLHLVIIKMFDDLPALGYLNDFFALILALISVFVCSMLMFHFVEKPGKTMIISVSRLFGNRK

Sequences:

>Translated_385_residues
MTYSVSATGDKSGVFLKSLTGIRLFAALAIVLHHVPGHFGISHELTEGWSLGQGVSVFFVLSGFILTYRYPALTDRAAIV
RFWVARVARIWPAHAFILFVLLLVNYDSMPDIESTSLKNILANVFLVQSWFPYAGYFFGYNSVSWSISTEMGFYLLFPFL
IFCFQKTWLLKVFISFSVGFVFVLLAYYMSIPSFQYPDNKIVMEGLIYVNPLARLFEFVAGMCSAFLWIKFHNRIVMNRV
LWTVLEVFSVLFLIFNVSFLSKIFSVFSFDFGFPGLYWKVMSLFPALAAAVFIFVMAKSEGFLSSVLSTRFFVYMGEVSF
SIYLLHLVIIKMFDDLPALGYLNDFFALILALISVFVCSMLMFHFVEKPGKTMIISVSRLFGNRK
>Mature_384_residues
TYSVSATGDKSGVFLKSLTGIRLFAALAIVLHHVPGHFGISHELTEGWSLGQGVSVFFVLSGFILTYRYPALTDRAAIVR
FWVARVARIWPAHAFILFVLLLVNYDSMPDIESTSLKNILANVFLVQSWFPYAGYFFGYNSVSWSISTEMGFYLLFPFLI
FCFQKTWLLKVFISFSVGFVFVLLAYYMSIPSFQYPDNKIVMEGLIYVNPLARLFEFVAGMCSAFLWIKFHNRIVMNRVL
WTVLEVFSVLFLIFNVSFLSKIFSVFSFDFGFPGLYWKVMSLFPALAAAVFIFVMAKSEGFLSSVLSTRFFVYMGEVSFS
IYLLHLVIIKMFDDLPALGYLNDFFALILALISVFVCSMLMFHFVEKPGKTMIISVSRLFGNRK

Specific function: Catalyzes the acylation of the mycaminose sugar during midecamycin biosynthesis [H]

COG id: COG1835

COG function: function code I; Predicted acyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002656 [H]

Pfam domain/function: PF01757 Acyl_transf_3 [H]

EC number: NA

Molecular weight: Translated: 43966; Mature: 43835

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYSVSATGDKSGVFLKSLTGIRLFAALAIVLHHVPGHFGISHELTEGWSLGQGVSVFFV
CEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHH
LSGFILTYRYPALTDRAAIVRFWVARVARIWPAHAFILFVLLLVNYDSMPDIESTSLKNI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LANVFLVQSWFPYAGYFFGYNSVSWSISTEMGFYLLFPFLIFCFQKTWLLKVFISFSVGF
HHHHHHHHHHCCHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFVLLAYYMSIPSFQYPDNKIVMEGLIYVNPLARLFEFVAGMCSAFLWIKFHNRIVMNRV
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LWTVLEVFSVLFLIFNVSFLSKIFSVFSFDFGFPGLYWKVMSLFPALAAAVFIFVMAKSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GFLSSVLSTRFFVYMGEVSFSIYLLHLVIIKMFDDLPALGYLNDFFALILALISVFVCSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LMFHFVEKPGKTMIISVSRLFGNRK
HHHHHHCCCCCEEEEEEHHHCCCCC
>Mature Secondary Structure 
TYSVSATGDKSGVFLKSLTGIRLFAALAIVLHHVPGHFGISHELTEGWSLGQGVSVFFV
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHHHH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HHHHHHCCCCCEEEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]