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The map label for this gene is zraS [C]

Identifier: 83594057

GI number: 83594057

Start: 3150536

End: 3153040

Strand: Direct

Name: zraS [C]

Synonym: Rru_A2725

Alternate gene names: 83594057

Gene position: 3150536-3153040 (Clockwise)

Preceding gene: 83594056

Following gene: 83594058

Centisome position: 72.38

GC content: 66.39

Gene sequence:

>2505_bases
ATGCCGACCGTGGACCCGGAACGCCTGAAAGGCGATACACTGGATCTTGCCAGCATCGGCCGCGACTTCGTCATCGGGCT
TAGCCTTATGGTCGTCGTCATGCTGGCGCTGGCGATCCCGACCATCCTTGATCGCCCCCTCCCCGATGCCGTCGTTCTGG
CCATCCTGATCCCGGGTCTGGCCCTGGTCCTGCTGTTGATCCGCCGCCAACGCACCCTGTTCAAGGCGATCGACCGATCG
GGGCGCCGGCTTGCCGATAGCGAAGCCCGGATCCGCGACTTCGCCCAATCGAGTTCCGACTGGTTCTGGGAAACCGGCCC
GACCCTGGCCTATACCTACGCCTCGCCCCGCCTGCTCGACCTGAGCGGCAACGATCCCGCCAAGATCATGGGCCAAAGGC
TGAGCGATCTTTGCCCGGATCCGCGCTCGGACGCCGCCGAACGCATCGCCACCCGCCGACCCTTTCGCGATCTGGCGCTG
ACCGTCGATCTGGGAGACGGCTATCGTCGTCATTTCCGTCTGGCCGGCCGACCGGTGCTCGATGATCGGGGCGTCTTCGC
CGGCTATCGGGGCGCCGGCGTCGATGTCACGGGCGAAATCGCCGCCAGCGCCCGCTCCGAGGCCTTGCGCGACCTGATGT
TCGACGCCGTCGACAGCATTTCCGAGGGCTTCGTGCTGTTCGACCCGGAAGGCCGGCTGGTGGTGGTCAACGACAGCTAC
CGTTATGCCTATCCGCAATTGGCCGATCATCTGGTTCCGGGCATCACCTTTGAAGAATTGCTGAAAGTGGCCGCCCGCGG
CCGTGACCTGGGCGCCGAGAAAGACCTGCGCGGCTGGATCGACGAGCGCCTGCACCGCCACCGCGAGGGCGGAACGAACG
ATTGCAAGTTATCGGACGGCCGCTGGTATCGGATCGGCGAGCATGAGACCCGGGGGGGCGGCTTGGTCAAGGTGTTGATG
GACATCACCGAGATGAAGACCGGCGCCGATCGTCTGGCCCAGCAAACCGCCCTGTTGCGCACCTTCGTCGATGAAACCCC
GGTGGCCGTCGCCATGGTCGATGCCACGTTACGCTATCTGCGGGTCAGCCGGCGCTGGCGGACGGAATTCGGTCTGGAGG
ACCGCGACATCATCGGCCAACGCCACGACGTAGTCATGCCCTCGCTGCCCGATGATTGGCTCAATGATTACGAACAGGCG
CTTTCGGGTGTCGCCATCGAACGCGAGGAGGTCTCGATCGATCTGGGCGGGCGGACCTTGTGGCTGCGCCGCCGCGAATA
TCCCTGGTTCCTCGAGGACGGCACGGTCGGCGGCTTGATGATGACGGCCGAGAACATCACCGAGCGCAAACAGGCCGAAC
TGGCCTTGCTGCAATCCCAGAAGATGGAGGCCGTTGGCCAGCTTGCCGGCGGCATCGCCCATGAATTCAATAACATGCTG
ACCTCGATCGGCGGCTTCGCCCGCATGGCCCAGCGCACGCCCGAGCGCTTGGAGCGCGTCACCATGTGTCTGGCCGAGGT
GGTGCGCTCGGCCGATCGCGCCGCCGGGCTGACCAGCCAGCTTTTGAACTTCAGCCGGCGCACCACCGAAGAGGAAACCC
TGCGCATTCCGCTGGGCGCCCTGCTTGATGAATTGCGCACCTTCCTGAAGCCGGTGCTGGGCGAACGCATCGCCTTGGAC
CTGCGCTGCGCCGTCGAGTCCTTGTTTGTTCTCGCCAACCGCGACCGGCTGCATCAGGCCCTGGTCAATCTGTGCATCAA
CGCCCGCGACGCCATGGCCGAGGGCGGAACCGTCATCATCGAGACCGGACACGGCGTGCCCCCTGAGCGCCTGCGCTGTC
GCCACCCCCATCTGGGCGCCGGCCAGCATGCGGTGCTGCGGGTCATCGATTCGGGCTGTGGCATTCCCGAAGAGGATCTG
CCCCGCGTCTTCGAGCCCTTCTTCACCACCAAGGCCCAGGGCAAGGGCACCGGTCTTGGCCTGCCGATGGTCTATGCCAT
GGCCGAACAGGCCAATGGCGCGGTGGAACTCGACTCGATCGTCGGTCGGGGGACGACGGTGACCCTCTATCTGCCCTTGG
CCGATGGCGCCGCCGCGGCGCCGACCATCGAAGGGCCGCCGCCCCTCCCGCGTGGCGGGGCGCGCATCCTGTTGGTCGAG
GACGAGGACGCCGTGCGCCGCTTCGCCGCCATGGTCCTGGAGGATGGCGGCTACGCCGTGCGGGCGGCGACCAATGGGCG
CGAGGCCCTCGACATCTGGGAGGCCGAGGGGGGGCGGTTCGATTTGCTGATCAGCGATCTGGTAATGCCCGAGCTGGGCG
GTCTCGCCCTTTATGACCGCCTGCGCGCCCACACCCCTTTGCTGCCGGCCGTGCTGATGTCAGGCTATTCCGACGAAATC
CCCTCGGAAGACGCGCGCGAGGGCGAGGGCGCCCGCCGGGTGCTTGCCAAACCGGTCACCCCGGATGCGCTGATCGCCGC
CGTCGAGGAGTTGCTGACGCCATGA

Upstream 100 bases:

>100_bases
CAGGGCTCCCCTCGACCTTGTTCTCCTTCCCCAACACGGCGTATCCTTGATCCTTGGATCCAACCGCCGGGGAAGGCCTG
AAAAGACGGGGCCGAGGGAG

Downstream 100 bases:

>100_bases
CCCCGCCCCTTTCCGCCTCGACCGATGGAGATCCCGCCACTCCCCCCACCGGCGCCGAGGACGGCCCTGGCGGCGCGCTC
TGCGTCGATCTGCGCGACAT

Product: multi-sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 834; Mature: 833

Protein sequence:

>834_residues
MPTVDPERLKGDTLDLASIGRDFVIGLSLMVVVMLALAIPTILDRPLPDAVVLAILIPGLALVLLLIRRQRTLFKAIDRS
GRRLADSEARIRDFAQSSSDWFWETGPTLAYTYASPRLLDLSGNDPAKIMGQRLSDLCPDPRSDAAERIATRRPFRDLAL
TVDLGDGYRRHFRLAGRPVLDDRGVFAGYRGAGVDVTGEIAASARSEALRDLMFDAVDSISEGFVLFDPEGRLVVVNDSY
RYAYPQLADHLVPGITFEELLKVAARGRDLGAEKDLRGWIDERLHRHREGGTNDCKLSDGRWYRIGEHETRGGGLVKVLM
DITEMKTGADRLAQQTALLRTFVDETPVAVAMVDATLRYLRVSRRWRTEFGLEDRDIIGQRHDVVMPSLPDDWLNDYEQA
LSGVAIEREEVSIDLGGRTLWLRRREYPWFLEDGTVGGLMMTAENITERKQAELALLQSQKMEAVGQLAGGIAHEFNNML
TSIGGFARMAQRTPERLERVTMCLAEVVRSADRAAGLTSQLLNFSRRTTEEETLRIPLGALLDELRTFLKPVLGERIALD
LRCAVESLFVLANRDRLHQALVNLCINARDAMAEGGTVIIETGHGVPPERLRCRHPHLGAGQHAVLRVIDSGCGIPEEDL
PRVFEPFFTTKAQGKGTGLGLPMVYAMAEQANGAVELDSIVGRGTTVTLYLPLADGAAAAPTIEGPPPLPRGGARILLVE
DEDAVRRFAAMVLEDGGYAVRAATNGREALDIWEAEGGRFDLLISDLVMPELGGLALYDRLRAHTPLLPAVLMSGYSDEI
PSEDAREGEGARRVLAKPVTPDALIAAVEELLTP

Sequences:

>Translated_834_residues
MPTVDPERLKGDTLDLASIGRDFVIGLSLMVVVMLALAIPTILDRPLPDAVVLAILIPGLALVLLLIRRQRTLFKAIDRS
GRRLADSEARIRDFAQSSSDWFWETGPTLAYTYASPRLLDLSGNDPAKIMGQRLSDLCPDPRSDAAERIATRRPFRDLAL
TVDLGDGYRRHFRLAGRPVLDDRGVFAGYRGAGVDVTGEIAASARSEALRDLMFDAVDSISEGFVLFDPEGRLVVVNDSY
RYAYPQLADHLVPGITFEELLKVAARGRDLGAEKDLRGWIDERLHRHREGGTNDCKLSDGRWYRIGEHETRGGGLVKVLM
DITEMKTGADRLAQQTALLRTFVDETPVAVAMVDATLRYLRVSRRWRTEFGLEDRDIIGQRHDVVMPSLPDDWLNDYEQA
LSGVAIEREEVSIDLGGRTLWLRRREYPWFLEDGTVGGLMMTAENITERKQAELALLQSQKMEAVGQLAGGIAHEFNNML
TSIGGFARMAQRTPERLERVTMCLAEVVRSADRAAGLTSQLLNFSRRTTEEETLRIPLGALLDELRTFLKPVLGERIALD
LRCAVESLFVLANRDRLHQALVNLCINARDAMAEGGTVIIETGHGVPPERLRCRHPHLGAGQHAVLRVIDSGCGIPEEDL
PRVFEPFFTTKAQGKGTGLGLPMVYAMAEQANGAVELDSIVGRGTTVTLYLPLADGAAAAPTIEGPPPLPRGGARILLVE
DEDAVRRFAAMVLEDGGYAVRAATNGREALDIWEAEGGRFDLLISDLVMPELGGLALYDRLRAHTPLLPAVLMSGYSDEI
PSEDAREGEGARRVLAKPVTPDALIAAVEELLTP
>Mature_833_residues
PTVDPERLKGDTLDLASIGRDFVIGLSLMVVVMLALAIPTILDRPLPDAVVLAILIPGLALVLLLIRRQRTLFKAIDRSG
RRLADSEARIRDFAQSSSDWFWETGPTLAYTYASPRLLDLSGNDPAKIMGQRLSDLCPDPRSDAAERIATRRPFRDLALT
VDLGDGYRRHFRLAGRPVLDDRGVFAGYRGAGVDVTGEIAASARSEALRDLMFDAVDSISEGFVLFDPEGRLVVVNDSYR
YAYPQLADHLVPGITFEELLKVAARGRDLGAEKDLRGWIDERLHRHREGGTNDCKLSDGRWYRIGEHETRGGGLVKVLMD
ITEMKTGADRLAQQTALLRTFVDETPVAVAMVDATLRYLRVSRRWRTEFGLEDRDIIGQRHDVVMPSLPDDWLNDYEQAL
SGVAIEREEVSIDLGGRTLWLRRREYPWFLEDGTVGGLMMTAENITERKQAELALLQSQKMEAVGQLAGGIAHEFNNMLT
SIGGFARMAQRTPERLERVTMCLAEVVRSADRAAGLTSQLLNFSRRTTEEETLRIPLGALLDELRTFLKPVLGERIALDL
RCAVESLFVLANRDRLHQALVNLCINARDAMAEGGTVIIETGHGVPPERLRCRHPHLGAGQHAVLRVIDSGCGIPEEDLP
RVFEPFFTTKAQGKGTGLGLPMVYAMAEQANGAVELDSIVGRGTTVTLYLPLADGAAAAPTIEGPPPLPRGGARILLVED
EDAVRRFAAMVLEDGGYAVRAATNGREALDIWEAEGGRFDLLISDLVMPELGGLALYDRLRAHTPLLPAVLMSGYSDEIP
SEDAREGEGARRVLAKPVTPDALIAAVEELLTP

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=241, Percent_Identity=34.0248962655602, Blast_Score=107, Evalue=5e-24,
Organism=Escherichia coli, GI1788549, Length=326, Percent_Identity=29.4478527607362, Blast_Score=106, Evalue=7e-24,
Organism=Escherichia coli, GI48994928, Length=530, Percent_Identity=24.3396226415094, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788713, Length=387, Percent_Identity=26.6149870801034, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI87081816, Length=305, Percent_Identity=27.5409836065574, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1789149, Length=410, Percent_Identity=23.4146341463415, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI145693157, Length=307, Percent_Identity=26.7100977198697, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91715; Mature: 91584

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTVDPERLKGDTLDLASIGRDFVIGLSLMVVVMLALAIPTILDRPLPDAVVLAILIPGL
CCCCCHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALVLLLIRRQRTLFKAIDRSGRRLADSEARIRDFAQSSSDWFWETGPTLAYTYASPRLLD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCCEEEEEECCCEEEE
LSGNDPAKIMGQRLSDLCPDPRSDAAERIATRRPFRDLALTVDLGDGYRRHFRLAGRPVL
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCCC
DDRGVFAGYRGAGVDVTGEIAASARSEALRDLMFDAVDSISEGFVLFDPEGRLVVVNDSY
CCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCC
RYAYPQLADHLVPGITFEELLKVAARGRDLGAEKDLRGWIDERLHRHREGGTNDCKLSDG
CCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCC
RWYRIGEHETRGGGLVKVLMDITEMKTGADRLAQQTALLRTFVDETPVAVAMVDATLRYL
CEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RVSRRWRTEFGLEDRDIIGQRHDVVMPSLPDDWLNDYEQALSGVAIEREEVSIDLGGRTL
HHHHHHHHHCCCCCHHHCCCCCCEECCCCCHHHHHHHHHHHHCCEEECCEEEEEECCEEE
WLRRREYPWFLEDGTVGGLMMTAENITERKQAELALLQSQKMEAVGQLAGGIAHEFNNML
EEEECCCCEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIGGFARMAQRTPERLERVTMCLAEVVRSADRAAGLTSQLLNFSRRTTEEETLRIPLGA
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEECCHHH
LLDELRTFLKPVLGERIALDLRCAVESLFVLANRDRLHQALVNLCINARDAMAEGGTVII
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHCCCCEEEE
ETGHGVPPERLRCRHPHLGAGQHAVLRVIDSGCGIPEEDLPRVFEPFFTTKAQGKGTGLG
ECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
LPMVYAMAEQANGAVELDSIVGRGTTVTLYLPLADGAAAAPTIEGPPPLPRGGARILLVE
HHHHHHHHHHCCCCEEEHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEC
DEDAVRRFAAMVLEDGGYAVRAATNGREALDIWEAEGGRFDLLISDLVMPELGGLALYDR
CHHHHHHHHHHHHCCCCEEEEEECCCCHHHEEEECCCCEEEEHHHHHHHHCCCCHHHHHH
LRAHTPLLPAVLMSGYSDEIPSEDAREGEGARRVLAKPVTPDALIAAVEELLTP
HHHCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTVDPERLKGDTLDLASIGRDFVIGLSLMVVVMLALAIPTILDRPLPDAVVLAILIPGL
CCCCHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALVLLLIRRQRTLFKAIDRSGRRLADSEARIRDFAQSSSDWFWETGPTLAYTYASPRLLD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCCEEEEEECCCEEEE
LSGNDPAKIMGQRLSDLCPDPRSDAAERIATRRPFRDLALTVDLGDGYRRHFRLAGRPVL
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHCCCCCCC
DDRGVFAGYRGAGVDVTGEIAASARSEALRDLMFDAVDSISEGFVLFDPEGRLVVVNDSY
CCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEECCC
RYAYPQLADHLVPGITFEELLKVAARGRDLGAEKDLRGWIDERLHRHREGGTNDCKLSDG
CCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEECCC
RWYRIGEHETRGGGLVKVLMDITEMKTGADRLAQQTALLRTFVDETPVAVAMVDATLRYL
CEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
RVSRRWRTEFGLEDRDIIGQRHDVVMPSLPDDWLNDYEQALSGVAIEREEVSIDLGGRTL
HHHHHHHHHCCCCCHHHCCCCCCEECCCCCHHHHHHHHHHHHCCEEECCEEEEEECCEEE
WLRRREYPWFLEDGTVGGLMMTAENITERKQAELALLQSQKMEAVGQLAGGIAHEFNNML
EEEECCCCEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSIGGFARMAQRTPERLERVTMCLAEVVRSADRAAGLTSQLLNFSRRTTEEETLRIPLGA
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEECCHHH
LLDELRTFLKPVLGERIALDLRCAVESLFVLANRDRLHQALVNLCINARDAMAEGGTVII
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHCCCCEEEE
ETGHGVPPERLRCRHPHLGAGQHAVLRVIDSGCGIPEEDLPRVFEPFFTTKAQGKGTGLG
ECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
LPMVYAMAEQANGAVELDSIVGRGTTVTLYLPLADGAAAAPTIEGPPPLPRGGARILLVE
HHHHHHHHHHCCCCEEEHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEC
DEDAVRRFAAMVLEDGGYAVRAATNGREALDIWEAEGGRFDLLISDLVMPELGGLALYDR
CHHHHHHHHHHHHCCCCEEEEEECCCCHHHEEEECCCCEEEEHHHHHHHHCCCCHHHHHH
LRAHTPLLPAVLMSGYSDEIPSEDAREGEGARRVLAKPVTPDALIAAVEELLTP
HHHCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA