Click here to switch to the map view.

The map label for this gene is ubiB [C]

Identifier: 83593528

GI number: 83593528

Start: 2548037

End: 2549395

Strand: Direct

Name: ubiB [C]

Synonym: Rru_A2193

Alternate gene names: 83593528

Gene position: 2548037-2549395 (Clockwise)

Preceding gene: 83593527

Following gene: 83593529

Centisome position: 58.54

GC content: 63.13

Gene sequence:

>1359_bases
ATGACCGAAAGCAATTCCCTTGGTGGGCGGTTTCGCCGCTATGCCCGCGTCTCCACCGCGATGGGCGGCATCGCCGCCCG
GGCGGCCGGCGAGAAATACCTGGGTTTCAAGGGCGATCGGGCGCGCATGGCCTCGGATCTGCGCGAGGCCCTGGGCGGAC
TGAAGGGCCCCTTGATGAAGGTGGCGCAGATCATGTCCACCATCCCCGACGCCCTGCCCCAGGAATTCACCGCCGAGCTG
ACCCAGCTTCAGGCCGATGCGCCACGCATGGGCTGGCCCTTCGTCAAACGGCGGATGACCGCCGAACTGGGTCCCAACTG
GCTGGGCCGCTTCGCCTCCTTCGATCACGACGCGGTCGCCGCCGCCTCGCTTGGCCAAGTCCACCGCGCCATCCACCTCG
ATGGCCGGGCTTTGGCCTGCAAGCTGCAATATCCCGATATGGACTCGACCGTCGAGGCCGACCTCAGCCAGCTCAAGATC
ATCATCGGCCTCTATCGGCGCTATGACGGCGCCATCGACCCGACCGAGATCCACGCCGAGATCACCGAGCGGCTGCGCGA
GGAACTCGATTACGCCCGCGAAGCCCGCAACATGCGGCTTTATCGCCATATGCTGCGCGACGAGGCCGGCGTTCATGTTC
CCGAACCGATCGCCGATCTGTCGACGAAGCGGCTTTTGACCATGACTTGGCTGCAGGGCGAACGCCTGCTGACCTTCATC
AATCACAGCCCGGAAGAGCGCAACCACCTCGCCTATAATATGTTCCGCGCCTGGTATGTGCCCTTCTATGACTACGGCGT
CATCCATGGCGACCCGCATCTGGGCAATTACACGGTGCGCGAAGACTTCTCGGTGAACCTGCTCGATTTCGGCACCATCC
GCGTCTTCCGCCCGGTCTTCGTCCAAGGGGTGATCGATCTTTATATCGCCCTGCGCGACAACGATCAGGAACGCGCCGTA
CACGCTTATGATTGCTGGGGATTTCGCGATCTGTCCAAGGACACGATCGCCGTCCTCAACCAATGGGCCAAGTTCATCTA
TGGCCCGCTTCTGGAAGACCGGGTGCGCAATATCCAGGAAGATCTGCCGATGGGCGGCAATCAGGGCCGACAGGTCGCCG
AAAAGGTCCACCAGGATCTCAAGGCGATCGGCGGCGTCACCCCGCCGCGCGAATTCGTGCTGATGGACCGGGCGGCCATC
GGTCTGGGCAGCGTCTTCTGGCATCTGAAAGCCGAGATCAACTGGTTCCAGATGTTCCACGAGCTGATCGACAATTTCGA
TGTCGACGCCCTGGCCCGCCGCCAGACCGAAGCCCTGACCGGCGTCGGCCTCGTGCCCAGTGACCTGGGCGTGGGCTGA

Upstream 100 bases:

>100_bases
ATATCAGCATTGTAGAGCGGTGTCCGAAGACTAGGTTTCACACATACCGCTCTAAAGGCGGTGGCATCAGCCACCGCCTT
GGCCGTAACGGGATGACCCT

Downstream 100 bases:

>100_bases
CCTTTTTTCATCCCGGGGGAGCCACGCTTGATGACCGCAGAGACGCAGCAGCAGACCCCGCTCCCCCGGGCCGGGCTTTT
TCTTGAAGACCTTGCGGTGG

Product: Abc1 protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MTESNSLGGRFRRYARVSTAMGGIAARAAGEKYLGFKGDRARMASDLREALGGLKGPLMKVAQIMSTIPDALPQEFTAEL
TQLQADAPRMGWPFVKRRMTAELGPNWLGRFASFDHDAVAAASLGQVHRAIHLDGRALACKLQYPDMDSTVEADLSQLKI
IIGLYRRYDGAIDPTEIHAEITERLREELDYAREARNMRLYRHMLRDEAGVHVPEPIADLSTKRLLTMTWLQGERLLTFI
NHSPEERNHLAYNMFRAWYVPFYDYGVIHGDPHLGNYTVREDFSVNLLDFGTIRVFRPVFVQGVIDLYIALRDNDQERAV
HAYDCWGFRDLSKDTIAVLNQWAKFIYGPLLEDRVRNIQEDLPMGGNQGRQVAEKVHQDLKAIGGVTPPREFVLMDRAAI
GLGSVFWHLKAEINWFQMFHELIDNFDVDALARRQTEALTGVGLVPSDLGVG

Sequences:

>Translated_452_residues
MTESNSLGGRFRRYARVSTAMGGIAARAAGEKYLGFKGDRARMASDLREALGGLKGPLMKVAQIMSTIPDALPQEFTAEL
TQLQADAPRMGWPFVKRRMTAELGPNWLGRFASFDHDAVAAASLGQVHRAIHLDGRALACKLQYPDMDSTVEADLSQLKI
IIGLYRRYDGAIDPTEIHAEITERLREELDYAREARNMRLYRHMLRDEAGVHVPEPIADLSTKRLLTMTWLQGERLLTFI
NHSPEERNHLAYNMFRAWYVPFYDYGVIHGDPHLGNYTVREDFSVNLLDFGTIRVFRPVFVQGVIDLYIALRDNDQERAV
HAYDCWGFRDLSKDTIAVLNQWAKFIYGPLLEDRVRNIQEDLPMGGNQGRQVAEKVHQDLKAIGGVTPPREFVLMDRAAI
GLGSVFWHLKAEINWFQMFHELIDNFDVDALARRQTEALTGVGLVPSDLGVG
>Mature_451_residues
TESNSLGGRFRRYARVSTAMGGIAARAAGEKYLGFKGDRARMASDLREALGGLKGPLMKVAQIMSTIPDALPQEFTAELT
QLQADAPRMGWPFVKRRMTAELGPNWLGRFASFDHDAVAAASLGQVHRAIHLDGRALACKLQYPDMDSTVEADLSQLKII
IGLYRRYDGAIDPTEIHAEITERLREELDYAREARNMRLYRHMLRDEAGVHVPEPIADLSTKRLLTMTWLQGERLLTFIN
HSPEERNHLAYNMFRAWYVPFYDYGVIHGDPHLGNYTVREDFSVNLLDFGTIRVFRPVFVQGVIDLYIALRDNDQERAVH
AYDCWGFRDLSKDTIAVLNQWAKFIYGPLLEDRVRNIQEDLPMGGNQGRQVAEKVHQDLKAIGGVTPPREFVLMDRAAIG
LGSVFWHLKAEINWFQMFHELIDNFDVDALARRQTEALTGVGLVPSDLGVG

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI34147522, Length=391, Percent_Identity=25.5754475703325, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI40254938, Length=298, Percent_Identity=26.8456375838926, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI27363457, Length=422, Percent_Identity=24.1706161137441, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI217416386, Length=365, Percent_Identity=23.8356164383562, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI217035081, Length=216, Percent_Identity=27.3148148148148, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI41393593, Length=267, Percent_Identity=28.0898876404494, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI2367309, Length=257, Percent_Identity=25.6809338521401, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32565180, Length=403, Percent_Identity=25.0620347394541, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17559152, Length=264, Percent_Identity=24.6212121212121, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321319, Length=267, Percent_Identity=28.4644194756554, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323282, Length=265, Percent_Identity=24.9056603773585, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI18859849, Length=288, Percent_Identity=27.0833333333333, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI22024280, Length=305, Percent_Identity=25.5737704918033, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24662575, Length=229, Percent_Identity=27.0742358078603, Blast_Score=86, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 51159; Mature: 51028

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESNSLGGRFRRYARVSTAMGGIAARAAGEKYLGFKGDRARMASDLREALGGLKGPLMK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
VAQIMSTIPDALPQEFTAELTQLQADAPRMGWPFVKRRMTAELGPNWLGRFASFDHDAVA
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCCHHHH
AASLGQVHRAIHLDGRALACKLQYPDMDSTVEADLSQLKIIIGLYRRYDGAIDPTEIHAE
HHHHHHHHHHHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ITERLREELDYAREARNMRLYRHMLRDEAGVHVPEPIADLSTKRLLTMTWLQGERLLTFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
NHSPEERNHLAYNMFRAWYVPFYDYGVIHGDPHLGNYTVREDFSVNLLDFGTIRVFRPVF
CCCCCHHHHHHHHHHHHHHCCHHHCCEEECCCCCCCEEECCCCEEEEEECCHHHHHHHHH
VQGVIDLYIALRDNDQERAVHAYDCWGFRDLSKDTIAVLNQWAKFIYGPLLEDRVRNIQE
HHHHHHHHEEECCCCHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLPMGGNQGRQVAEKVHQDLKAIGGVTPPREFVLMDRAAIGLGSVFWHLKAEINWFQMFH
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELIDNFDVDALARRQTEALTGVGLVPSDLGVG
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TESNSLGGRFRRYARVSTAMGGIAARAAGEKYLGFKGDRARMASDLREALGGLKGPLMK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
VAQIMSTIPDALPQEFTAELTQLQADAPRMGWPFVKRRMTAELGPNWLGRFASFDHDAVA
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHHHHHCCCCHHHH
AASLGQVHRAIHLDGRALACKLQYPDMDSTVEADLSQLKIIIGLYRRYDGAIDPTEIHAE
HHHHHHHHHHHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ITERLREELDYAREARNMRLYRHMLRDEAGVHVPEPIADLSTKRLLTMTWLQGERLLTFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHH
NHSPEERNHLAYNMFRAWYVPFYDYGVIHGDPHLGNYTVREDFSVNLLDFGTIRVFRPVF
CCCCCHHHHHHHHHHHHHHCCHHHCCEEECCCCCCCEEECCCCEEEEEECCHHHHHHHHH
VQGVIDLYIALRDNDQERAVHAYDCWGFRDLSKDTIAVLNQWAKFIYGPLLEDRVRNIQE
HHHHHHHHEEECCCCHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLPMGGNQGRQVAEKVHQDLKAIGGVTPPREFVLMDRAAIGLGSVFWHLKAEINWFQMFH
HCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELIDNFDVDALARRQTEALTGVGLVPSDLGVG
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA