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The map label for this gene is pitA [C]

Identifier: 83593369

GI number: 83593369

Start: 2348773

End: 2350269

Strand: Direct

Name: pitA [C]

Synonym: Rru_A2034

Alternate gene names: 83593369

Gene position: 2348773-2350269 (Clockwise)

Preceding gene: 83593368

Following gene: 83593370

Centisome position: 53.96

GC content: 65.8

Gene sequence:

>1497_bases
ATGATTTCCCCAAGCGGTCCGAAGAATATGAAAAAGCTCCATAAGGAGCTCAAACGCTTCTCGGCGATCGAAGCCGGTTT
GGCGATCACCGGCCGACCGGCGGTCGGCATCGGTCTGGCTGTGGTTTTCCTGGGCGTGATCTGGGCCTTCACGGCGATGA
CCTTTGGCCAAACCCCGTCCCATACCTTTCTCGTCCTCGCCGCCGTCGTCGGCGGCTATATGGCGCTCAACATCGGCGCC
AATGACGTCGCCAATAATATGGGACCGGCCGTCGGCTCGCGGGCGATGACCATGGCCGGGGCGCTGTTGATTGCCGCCAT
CTGCGAAGCCTCGGGGGCCATCCTGGCCGGTGGCGACGTGGTCGAGACGATTTCCAAGGGGATCATCGATCCCGGAGCGA
TGTCCGATAACGTGAAATTCGTCCAGGTGATGATCGCCGCCCTTCTCGCCTCGGCGCTATGGGTCAACCTCGCGACCTAT
CTCAACGCCCCGGTCTCGACCACCCATGCCATCGTCGGCGGGGTGATGGGCGCGGGGGCCCTCGCCGCCGGCGTCGGCGC
GGTTCATTGGAGCACCGTCGGGGCGATCGTCGCCAGTTGGGTCATCTCGCCGATGATGGGCGGCGTCATCGCCGCCGCCC
TACTGCTCTTCGTCAAAAAGATGATCTTGTTCCAAGACGACAAGATCGCCGCCGCCCGCCGCTGGATCCCGGTGCTGATC
GGCCTGATGGCCGGCGCCTTTGGCATGTATCTGCTGACCAAGGGCCTCGCCCGCGTCTATGCGCCGCCCTCCTGGCTGGT
CGGCCTCGCCGGCGTCGGATCGTTCCTTGGCGTCTGGGCGCTCATGCGTCCGATCGTTCGCCGCCAGACGGTGGAAATGG
AGAACCGGCGCAAGGCGGTGAGCGGCCTTTTCACCCATGCCCTGATCTTTTCCTCGGCCCTGCTGTCCTTCGCCCATGGC
GCCAATGACGTCGCCAATGCGGTGGGACCGCTTGCCGCCATCGCCAATGCCCTGGCCGGCGGCGGGGTGGAGGACCAAGC
CGTGGTCCTGCCACTGTGGATCCTCGTGGTCGGCGCGGCGGGCATCTCGGCCGGGCTGTTCCTGTTTGGTCCGAAGCTGA
TCCGCACCGTCGGCGAAAAAATCACCAAGCTCGACCGCGCCCGGGCCTTCTGCGTCTCGCTTTCGGCCGCCGTCACCGTT
CTCGCCGCCTCGGGGCTGGGGCTGCCGGTCAGTTCGACCCATATCGCCGTTGGCGCCGTTTTCGGGGTCGGCTTCCTGCG
CGAGGCCCTGGCCAATCACCAGGAACTGTCCCATCTGGTGCATCCGCCCCGGCTCGATGCGATCGACAACCCGCAGCGCG
TGGAAAAGCTGGAACGGCGCCGTCTGGTCCGCCGCCAGCACATCACGACCATTGGCGCGGCCTGGGTGGTGACCGTTCCC
CTTTCGGCGGCGCTCTCGGCGGGGTTATACCTGCTGCTCACCGCCTTCCTGGAGTAG

Upstream 100 bases:

>100_bases
TAATCCTCGGCGCGATGACATTTTTACTTCATTTTTATGACGGAATCCCCGATGACTGCGCGCGATGCCCTTCCCCCGCG
CTGACAGTCAGAGGACGAGG

Downstream 100 bases:

>100_bases
CCTCATGCCGCCCCGCTCCCCTATTCGCCTGTCCCTTGCCATCCTTGGTCTGCTTGGCGGACTGCTGGGGGGAGGAGCCG
AGCCGGCGCGCGCGGCCGAA

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MISPSGPKNMKKLHKELKRFSAIEAGLAITGRPAVGIGLAVVFLGVIWAFTAMTFGQTPSHTFLVLAAVVGGYMALNIGA
NDVANNMGPAVGSRAMTMAGALLIAAICEASGAILAGGDVVETISKGIIDPGAMSDNVKFVQVMIAALLASALWVNLATY
LNAPVSTTHAIVGGVMGAGALAAGVGAVHWSTVGAIVASWVISPMMGGVIAAALLLFVKKMILFQDDKIAAARRWIPVLI
GLMAGAFGMYLLTKGLARVYAPPSWLVGLAGVGSFLGVWALMRPIVRRQTVEMENRRKAVSGLFTHALIFSSALLSFAHG
ANDVANAVGPLAAIANALAGGGVEDQAVVLPLWILVVGAAGISAGLFLFGPKLIRTVGEKITKLDRARAFCVSLSAAVTV
LAASGLGLPVSSTHIAVGAVFGVGFLREALANHQELSHLVHPPRLDAIDNPQRVEKLERRRLVRRQHITTIGAAWVVTVP
LSAALSAGLYLLLTAFLE

Sequences:

>Translated_498_residues
MISPSGPKNMKKLHKELKRFSAIEAGLAITGRPAVGIGLAVVFLGVIWAFTAMTFGQTPSHTFLVLAAVVGGYMALNIGA
NDVANNMGPAVGSRAMTMAGALLIAAICEASGAILAGGDVVETISKGIIDPGAMSDNVKFVQVMIAALLASALWVNLATY
LNAPVSTTHAIVGGVMGAGALAAGVGAVHWSTVGAIVASWVISPMMGGVIAAALLLFVKKMILFQDDKIAAARRWIPVLI
GLMAGAFGMYLLTKGLARVYAPPSWLVGLAGVGSFLGVWALMRPIVRRQTVEMENRRKAVSGLFTHALIFSSALLSFAHG
ANDVANAVGPLAAIANALAGGGVEDQAVVLPLWILVVGAAGISAGLFLFGPKLIRTVGEKITKLDRARAFCVSLSAAVTV
LAASGLGLPVSSTHIAVGAVFGVGFLREALANHQELSHLVHPPRLDAIDNPQRVEKLERRRLVRRQHITTIGAAWVVTVP
LSAALSAGLYLLLTAFLE
>Mature_498_residues
MISPSGPKNMKKLHKELKRFSAIEAGLAITGRPAVGIGLAVVFLGVIWAFTAMTFGQTPSHTFLVLAAVVGGYMALNIGA
NDVANNMGPAVGSRAMTMAGALLIAAICEASGAILAGGDVVETISKGIIDPGAMSDNVKFVQVMIAALLASALWVNLATY
LNAPVSTTHAIVGGVMGAGALAAGVGAVHWSTVGAIVASWVISPMMGGVIAAALLLFVKKMILFQDDKIAAARRWIPVLI
GLMAGAFGMYLLTKGLARVYAPPSWLVGLAGVGSFLGVWALMRPIVRRQTVEMENRRKAVSGLFTHALIFSSALLSFAHG
ANDVANAVGPLAAIANALAGGGVEDQAVVLPLWILVVGAAGISAGLFLFGPKLIRTVGEKITKLDRARAFCVSLSAAVTV
LAASGLGLPVSSTHIAVGAVFGVGFLREALANHQELSHLVHPPRLDAIDNPQRVEKLERRRLVRRQHITTIGAAWVVTVP
LSAALSAGLYLLLTAFLE

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI5803173, Length=253, Percent_Identity=33.201581027668, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI31543630, Length=238, Percent_Identity=33.6134453781513, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25146401, Length=500, Percent_Identity=29, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71981576, Length=475, Percent_Identity=30.9473684210526, Blast_Score=177, Evalue=9e-45,
Organism=Caenorhabditis elegans, GI17557328, Length=478, Percent_Identity=26.9874476987448, Blast_Score=138, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI32566716, Length=251, Percent_Identity=33.4661354581673, Blast_Score=125, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17539280, Length=216, Percent_Identity=34.2592592592593, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17536725, Length=206, Percent_Identity=27.6699029126214, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319773, Length=120, Percent_Identity=37.5, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356511, Length=233, Percent_Identity=35.6223175965665, Blast_Score=135, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 51569; Mature: 51569

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISPSGPKNMKKLHKELKRFSAIEAGLAITGRPAVGIGLAVVFLGVIWAFTAMTFGQTPS
CCCCCCCHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
HTFLVLAAVVGGYMALNIGANDVANNMGPAVGSRAMTMAGALLIAAICEASGAILAGGDV
HHHHHHHHHHCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCHH
VETISKGIIDPGAMSDNVKFVQVMIAALLASALWVNLATYLNAPVSTTHAIVGGVMGAGA
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LAAGVGAVHWSTVGAIVASWVISPMMGGVIAAALLLFVKKMILFQDDKIAAARRWIPVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GLMAGAFGMYLLTKGLARVYAPPSWLVGLAGVGSFLGVWALMRPIVRRQTVEMENRRKAV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLFTHALIFSSALLSFAHGANDVANAVGPLAAIANALAGGGVEDQAVVLPLWILVVGAA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GISAGLFLFGPKLIRTVGEKITKLDRARAFCVSLSAAVTVLAASGLGLPVSSTHIAVGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
FGVGFLREALANHQELSHLVHPPRLDAIDNPQRVEKLERRRLVRRQHITTIGAAWVVTVP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAALSAGLYLLLTAFLE
HHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MISPSGPKNMKKLHKELKRFSAIEAGLAITGRPAVGIGLAVVFLGVIWAFTAMTFGQTPS
CCCCCCCHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
HTFLVLAAVVGGYMALNIGANDVANNMGPAVGSRAMTMAGALLIAAICEASGAILAGGDV
HHHHHHHHHHCCCEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCHH
VETISKGIIDPGAMSDNVKFVQVMIAALLASALWVNLATYLNAPVSTTHAIVGGVMGAGA
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LAAGVGAVHWSTVGAIVASWVISPMMGGVIAAALLLFVKKMILFQDDKIAAARRWIPVLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GLMAGAFGMYLLTKGLARVYAPPSWLVGLAGVGSFLGVWALMRPIVRRQTVEMENRRKAV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGLFTHALIFSSALLSFAHGANDVANAVGPLAAIANALAGGGVEDQAVVLPLWILVVGAA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
GISAGLFLFGPKLIRTVGEKITKLDRARAFCVSLSAAVTVLAASGLGLPVSSTHIAVGAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
FGVGFLREALANHQELSHLVHPPRLDAIDNPQRVEKLERRRLVRRQHITTIGAAWVVTVP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAALSAGLYLLLTAFLE
HHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]