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The map label for this gene is appC [H]

Identifier: 83593347

GI number: 83593347

Start: 2326401

End: 2327231

Strand: Reverse

Name: appC [H]

Synonym: Rru_A2012

Alternate gene names: 83593347

Gene position: 2327231-2326401 (Counterclockwise)

Preceding gene: 83593348

Following gene: 83593346

Centisome position: 53.46

GC content: 65.82

Gene sequence:

>831_bases
ATGGCCGCTTTTCGTCGCTATTTCCGCAATCCGTCGGCCGTGCTCGGGCTGGTCTTGCTGATCGCCGTCCTCGGTTTGGC
GCTCAGCGCCGATCTGTTGTTCCCGCGCGATCCCCTGGCCCTGGCCGGACGGCCGCTGCAATGGCCGCTAGACAATCCCC
GCTTCTGGCTGGGGACGGATAATTCGGGGCGCGATATCGCCGCCCAGATCTTCCATGGCGCCCGGCTGTCGCTGGTGATC
GGCGTCGTCGCCACCTCGATCGCCATCGCGCTCGGCGTGCTGGTCGGCGCCCTGGCCGGCTATTACGGCGGGCTGGTCGA
TGACGCCCTGATGCGCATCACCGACGCCTTTCAGACCCTGCCGAATTTCCTGTTGCTGCTGCTGCTGATCGCGGTTTTCG
GCTCGCGCATCGAAACCGTGGTGATCGCCATCGGCATCGTCTCGTGGCCGGCGCCGGCTAGGCTGACCCGGGCGGAGTTC
CTGTCGCTGCGCGGGCGGGAATTCGTTCAGGCCGCCCGCCTTGCCGGCCTGCGCGACCTGCGGCTGATCTTCCGCGAGAT
CCTGCCCAACGCCCTGCCGCCGATCATCGTTTACGCCAGCGTGGTGATGGCGACGGCCATCTTGCTGGAAAGCGCGCTGG
CCTTCCTTAATCTGTCTGACCCCAATGTGTCCTCGTGGGGCAATCTGATCGGCCAGGGCCGGGGGGTGCTGCGCAGCGAG
TGGTATGTTTCGGCCATCCCCGGCTTTGCCATTCTTCTGACCGTTCTGGCGGTGTCGCTTGTCGGCCAGGGGCTGAACGA
CGCCCTTAACCCAAGGCTTGCCGACCAATGA

Upstream 100 bases:

>100_bases
GTCTTGCTGTCGGCGGTTCTGGTGATCGTCGTCAATTTCATCGTCGACCTGCTGTATGCCCGGCTTGATCCGCGCATCCG
CGCCAAAGGACACTGAAGCG

Downstream 100 bases:

>100_bases
CCGCGCCGACCCTTCCCTTGGCCTCCCCCCGCCTGATTATCGACGATCTGCGCGTCGCCCTGCCTAAAAGCGCCGACCGT
CCCTTCGCCCTAAACGGCAT

Product: binding-protein dependent transport system inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MAAFRRYFRNPSAVLGLVLLIAVLGLALSADLLFPRDPLALAGRPLQWPLDNPRFWLGTDNSGRDIAAQIFHGARLSLVI
GVVATSIAIALGVLVGALAGYYGGLVDDALMRITDAFQTLPNFLLLLLLIAVFGSRIETVVIAIGIVSWPAPARLTRAEF
LSLRGREFVQAARLAGLRDLRLIFREILPNALPPIIVYASVVMATAILLESALAFLNLSDPNVSSWGNLIGQGRGVLRSE
WYVSAIPGFAILLTVLAVSLVGQGLNDALNPRLADQ

Sequences:

>Translated_276_residues
MAAFRRYFRNPSAVLGLVLLIAVLGLALSADLLFPRDPLALAGRPLQWPLDNPRFWLGTDNSGRDIAAQIFHGARLSLVI
GVVATSIAIALGVLVGALAGYYGGLVDDALMRITDAFQTLPNFLLLLLLIAVFGSRIETVVIAIGIVSWPAPARLTRAEF
LSLRGREFVQAARLAGLRDLRLIFREILPNALPPIIVYASVVMATAILLESALAFLNLSDPNVSSWGNLIGQGRGVLRSE
WYVSAIPGFAILLTVLAVSLVGQGLNDALNPRLADQ
>Mature_275_residues
AAFRRYFRNPSAVLGLVLLIAVLGLALSADLLFPRDPLALAGRPLQWPLDNPRFWLGTDNSGRDIAAQIFHGARLSLVIG
VVATSIAIALGVLVGALAGYYGGLVDDALMRITDAFQTLPNFLLLLLLIAVFGSRIETVVIAIGIVSWPAPARLTRAEFL
SLRGREFVQAARLAGLRDLRLIFREILPNALPPIIVYASVVMATAILLESALAFLNLSDPNVSSWGNLIGQGRGVLRSEW
YVSAIPGFAILLTVLAVSLVGQGLNDALNPRLADQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=38.4057971014493, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789964, Length=282, Percent_Identity=40.7801418439716, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787760, Length=219, Percent_Identity=37.8995433789954, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1787498, Length=273, Percent_Identity=34.7985347985348, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789889, Length=249, Percent_Identity=32.1285140562249, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1788505, Length=221, Percent_Identity=33.0316742081448, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787549, Length=273, Percent_Identity=27.1062271062271, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29598; Mature: 29467

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFRRYFRNPSAVLGLVLLIAVLGLALSADLLFPRDPLALAGRPLQWPLDNPRFWLGTD
CHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCEEEECC
NSGRDIAAQIFHGARLSLVIGVVATSIAIALGVLVGALAGYYGGLVDDALMRITDAFQTL
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PNFLLLLLLIAVFGSRIETVVIAIGIVSWPAPARLTRAEFLSLRGREFVQAARLAGLRDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCHHHH
RLIFREILPNALPPIIVYASVVMATAILLESALAFLNLSDPNVSSWGNLIGQGRGVLRSE
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHC
WYVSAIPGFAILLTVLAVSLVGQGLNDALNPRLADQ
HHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure 
AAFRRYFRNPSAVLGLVLLIAVLGLALSADLLFPRDPLALAGRPLQWPLDNPRFWLGTD
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCEEEECC
NSGRDIAAQIFHGARLSLVIGVVATSIAIALGVLVGALAGYYGGLVDDALMRITDAFQTL
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PNFLLLLLLIAVFGSRIETVVIAIGIVSWPAPARLTRAEFLSLRGREFVQAARLAGLRDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCHHHH
RLIFREILPNALPPIIVYASVVMATAILLESALAFLNLSDPNVSSWGNLIGQGRGVLRSE
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHC
WYVSAIPGFAILLTVLAVSLVGQGLNDALNPRLADQ
HHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]