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The map label for this gene is sir2 [H]

Identifier: 83593266

GI number: 83593266

Start: 2236793

End: 2238463

Strand: Reverse

Name: sir2 [H]

Synonym: Rru_A1931

Alternate gene names: 83593266

Gene position: 2238463-2236793 (Counterclockwise)

Preceding gene: 83593267

Following gene: 83593265

Centisome position: 51.43

GC content: 66.19

Gene sequence:

>1671_bases
ATGTATCGTTACGATGAATTCGATGCCGCCATTGTCGCCGACCGGATCAGCGAATTCCGCGATCAGGTGAACCGCCGCCT
GTCGGGGGAGCTTGACGAGGAGGCCTTTCGCCCCCTGCGGCTGATGAACGGCGTCTATCTGCAGCTCCATGCCTATATGC
TGCGGGTCTGCATCCCCTATGGCGAGATCAACGCCACCCAGTTGCGCCGCCTGGGCGCCATCGCCCAGCGCTATGATCGC
GGCTATGGCCATTTCACCACCCGGCAGAACATCCAGTTCAACTGGGTCGCCCTGTCGGATATTCCCGCCGTTCTGGAAGA
GTTGGCCGAGGTCGGGATGCATGCCATTCAGACCAGCGGCAACTGCATCCGCAACACCACCACCGATCCCTTGGCCGGCG
TCGCCGCCGACGAGGTCGAAGATCCCCGGCCCTGGGCCGAGCTGATCCGCCAGTGGTCGACCTTCCACCCCGAATTCACC
TTCTTGCCGCGCAAGTTCAAGGTCGCCATCACCGGCGCCAGCCATGACCGCGCCGCCATCCGCTTCCATGACATCGGCCT
GGAACTGGCGCCGATCGGCGGCGGCGAGATCGGCTTCAAGGTCTTCGTCGGCGGCGGCATGGGCCGCACCCCGCGCCTGG
GTCGGCTGTTGCGCGACGACCTGCCCAAACAACACCTGCTGAGCTACATCGAGGCCATCTTGCGGGTCTATAACCGCCAG
GGCCAGCGCGAGAACAAATACAAGGCGCGGATCAAGATCCTGGTCGACAGCCTGGGGGTCGAGGCCTTCCGCGCCGAGGT
CGATGCGGAATGGGAGGCGATGGGCCGGGCCACCATCGATGTGCCCGAGGCCGAGATCGCCCGCATCCAAAGCTATTTCG
TGCCCCAAGACAGCGCCCCCGAGGACGGCGGGCTGGCGGCCTCGCGCGCCATCACCAAGCGCCGCGCCAGCGACCCGGCC
TTCGCCGGCTGGCTCGATGCCAATGTCCATGCCCATAAGGTGGCCGGCCATGCCGGGGTGACGATTTCGCTGAAACCCGC
AGGGGGCATTCCGGGCGACGCCACCACCGCCCAGCTTGAAACCATCGCCGATCTGGCCGAGCGCTATTCCAAGGGGCTGC
TGCGGGTCACCCACGAGCAGAACCTGCTGCTGCCCCATGTTCGCCAAGAAGATCTGCCCGCGCTCTGGGCCGCTCTGGTC
GCGGCCGGGCTGGAAACCGCCAATGTCGGGCGGATCGGCGATATCATCAGCTGCCCGGGCCTGGATTACTGCTCCTTGGC
CACGGCGCGTTCGATCCCCATCGCCCAGGCGCTCAGCGCCCGTTTCGCCGATCCGGCCCGCCTGCGCGACATCGGCCCGA
TCACCCTGAACATCAGCGGCTGCATCAACGCCTGCGGCCACCACCACGCGGGCAATATCGGCATCCTCGGGCTCGAGAAG
ACCGGCAACGAGGCTTACCAACTGGTGCTGGGCGGCGCCGCCGATGAAACCGCCGCCATCGCCCGCATCACCGGCCAGGG
CTTTTCCGCCGACGCCATCGTCGGCGCGGTGGAAACCGTGGTCGATACCTACATCGGCCTGCGCCAGGACGGCGAGACCT
TCATCGAGACCTTCCGCCGGGTTGGCGTGACCCCCTTCAAGGAGGCCCTTTATGGCTCCGTTGCGGCTTGA

Upstream 100 bases:

>100_bases
AACCCGCCCATTTGCGCGAAAGGATCCGCGCCCAGGGCCCCACCGTCCAGGCCGGCGCCGGTCTTCCCCTGTCCAAGATC
CAGTCCAAGGCTTCCTGATC

Downstream 100 bases:

>100_bases
TCGCCCGGTTCGTCCGGCCTCGGACCTTGTCGTGCTCGACGCCCTGGCGGCGCTTCCCGACGATGGCAAGGCGCTGGTTC
CCTTGTCGCGCTGGAAAGGC

Product: ferredoxin--nitrite reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MYRYDEFDAAIVADRISEFRDQVNRRLSGELDEEAFRPLRLMNGVYLQLHAYMLRVCIPYGEINATQLRRLGAIAQRYDR
GYGHFTTRQNIQFNWVALSDIPAVLEELAEVGMHAIQTSGNCIRNTTTDPLAGVAADEVEDPRPWAELIRQWSTFHPEFT
FLPRKFKVAITGASHDRAAIRFHDIGLELAPIGGGEIGFKVFVGGGMGRTPRLGRLLRDDLPKQHLLSYIEAILRVYNRQ
GQRENKYKARIKILVDSLGVEAFRAEVDAEWEAMGRATIDVPEAEIARIQSYFVPQDSAPEDGGLAASRAITKRRASDPA
FAGWLDANVHAHKVAGHAGVTISLKPAGGIPGDATTAQLETIADLAERYSKGLLRVTHEQNLLLPHVRQEDLPALWAALV
AAGLETANVGRIGDIISCPGLDYCSLATARSIPIAQALSARFADPARLRDIGPITLNISGCINACGHHHAGNIGILGLEK
TGNEAYQLVLGGAADETAAIARITGQGFSADAIVGAVETVVDTYIGLRQDGETFIETFRRVGVTPFKEALYGSVAA

Sequences:

>Translated_556_residues
MYRYDEFDAAIVADRISEFRDQVNRRLSGELDEEAFRPLRLMNGVYLQLHAYMLRVCIPYGEINATQLRRLGAIAQRYDR
GYGHFTTRQNIQFNWVALSDIPAVLEELAEVGMHAIQTSGNCIRNTTTDPLAGVAADEVEDPRPWAELIRQWSTFHPEFT
FLPRKFKVAITGASHDRAAIRFHDIGLELAPIGGGEIGFKVFVGGGMGRTPRLGRLLRDDLPKQHLLSYIEAILRVYNRQ
GQRENKYKARIKILVDSLGVEAFRAEVDAEWEAMGRATIDVPEAEIARIQSYFVPQDSAPEDGGLAASRAITKRRASDPA
FAGWLDANVHAHKVAGHAGVTISLKPAGGIPGDATTAQLETIADLAERYSKGLLRVTHEQNLLLPHVRQEDLPALWAALV
AAGLETANVGRIGDIISCPGLDYCSLATARSIPIAQALSARFADPARLRDIGPITLNISGCINACGHHHAGNIGILGLEK
TGNEAYQLVLGGAADETAAIARITGQGFSADAIVGAVETVVDTYIGLRQDGETFIETFRRVGVTPFKEALYGSVAA
>Mature_556_residues
MYRYDEFDAAIVADRISEFRDQVNRRLSGELDEEAFRPLRLMNGVYLQLHAYMLRVCIPYGEINATQLRRLGAIAQRYDR
GYGHFTTRQNIQFNWVALSDIPAVLEELAEVGMHAIQTSGNCIRNTTTDPLAGVAADEVEDPRPWAELIRQWSTFHPEFT
FLPRKFKVAITGASHDRAAIRFHDIGLELAPIGGGEIGFKVFVGGGMGRTPRLGRLLRDDLPKQHLLSYIEAILRVYNRQ
GQRENKYKARIKILVDSLGVEAFRAEVDAEWEAMGRATIDVPEAEIARIQSYFVPQDSAPEDGGLAASRAITKRRASDPA
FAGWLDANVHAHKVAGHAGVTISLKPAGGIPGDATTAQLETIADLAERYSKGLLRVTHEQNLLLPHVRQEDLPALWAALV
AAGLETANVGRIGDIISCPGLDYCSLATARSIPIAQALSARFADPARLRDIGPITLNISGCINACGHHHAGNIGILGLEK
TGNEAYQLVLGGAADETAAIARITGQGFSADAIVGAVETVVDTYIGLRQDGETFIETFRRVGVTPFKEALYGSVAA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322597, Length=585, Percent_Identity=22.2222222222222, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 60610; Mature: 60610

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRYDEFDAAIVADRISEFRDQVNRRLSGELDEEAFRPLRLMNGVYLQLHAYMLRVCIPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GEINATQLRRLGAIAQRYDRGYGHFTTRQNIQFNWVALSDIPAVLEELAEVGMHAIQTSG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCC
NCIRNTTTDPLAGVAADEVEDPRPWAELIRQWSTFHPEFTFLPRKFKVAITGASHDRAAI
CEEECCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCEEECCCEEEEEEECCCCCCEEE
RFHDIGLELAPIGGGEIGFKVFVGGGMGRTPRLGRLLRDDLPKQHLLSYIEAILRVYNRQ
EEEECCEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
GQRENKYKARIKILVDSLGVEAFRAEVDAEWEAMGRATIDVPEAEIARIQSYFVPQDSAP
CCCCHHHHHHHEEHHHHHCHHHHHHHCCCCHHHCCCEEECCCHHHHHHHHHHCCCCCCCC
EDGGLAASRAITKRRASDPAFAGWLDANVHAHKVAGHAGVTISLKPAGGIPGDATTAQLE
CCCCCHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCCCEEEEEECCCCCCCCCHHHHHH
TIADLAERYSKGLLRVTHEQNLLLPHVRQEDLPALWAALVAAGLETANVGRIGDIISCPG
HHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LDYCSLATARSIPIAQALSARFADPARLRDIGPITLNISGCINACGHHHAGNIGILGLEK
CCHHHHHHHCCCCHHHHHHHHCCCCHHHCCCCCEEEEHHHHHHHCCCCCCCCEEEEEEEC
TGNEAYQLVLGGAADETAAIARITGQGFSADAIVGAVETVVDTYIGLRQDGETFIETFRR
CCCCEEEEEECCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VGVTPFKEALYGSVAA
CCCCHHHHHHHHCCCC
>Mature Secondary Structure
MYRYDEFDAAIVADRISEFRDQVNRRLSGELDEEAFRPLRLMNGVYLQLHAYMLRVCIPY
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GEINATQLRRLGAIAQRYDRGYGHFTTRQNIQFNWVALSDIPAVLEELAEVGMHAIQTSG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCC
NCIRNTTTDPLAGVAADEVEDPRPWAELIRQWSTFHPEFTFLPRKFKVAITGASHDRAAI
CEEECCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCEEECCCEEEEEEECCCCCCEEE
RFHDIGLELAPIGGGEIGFKVFVGGGMGRTPRLGRLLRDDLPKQHLLSYIEAILRVYNRQ
EEEECCEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
GQRENKYKARIKILVDSLGVEAFRAEVDAEWEAMGRATIDVPEAEIARIQSYFVPQDSAP
CCCCHHHHHHHEEHHHHHCHHHHHHHCCCCHHHCCCEEECCCHHHHHHHHHHCCCCCCCC
EDGGLAASRAITKRRASDPAFAGWLDANVHAHKVAGHAGVTISLKPAGGIPGDATTAQLE
CCCCCHHHHHHHHHCCCCCCCCCEEECCCCCEEECCCCCEEEEEECCCCCCCCCHHHHHH
TIADLAERYSKGLLRVTHEQNLLLPHVRQEDLPALWAALVAAGLETANVGRIGDIISCPG
HHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LDYCSLATARSIPIAQALSARFADPARLRDIGPITLNISGCINACGHHHAGNIGILGLEK
CCHHHHHHHCCCCHHHHHHHHCCCCHHHCCCCCEEEEHHHHHHHCCCCCCCCEEEEEEEC
TGNEAYQLVLGGAADETAAIARITGQGFSADAIVGAVETVVDTYIGLRQDGETFIETFRR
CCCCEEEEEECCCCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
VGVTPFKEALYGSVAA
CCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA