Click here to switch to the map view.

The map label for this gene is queD [H]

Identifier: 83593166

GI number: 83593166

Start: 2128405

End: 2128980

Strand: Reverse

Name: queD [H]

Synonym: Rru_A1831

Alternate gene names: 83593166

Gene position: 2128980-2128405 (Counterclockwise)

Preceding gene: 83593167

Following gene: 83593165

Centisome position: 48.91

GC content: 64.76

Gene sequence:

>576_bases
ATGTTTGAAATAACCCGAAAAATCGAAATAGACGCCGGCCATCGCATTCGCGAGCATGGCTCGAAATGCCGCAATCTCCA
CGGGCATCGCTATCAGATCCACGTCAGCGTGCGCAGCGACCAGCTGGTGGCGGGTGGGTCGGAAAGCGGCATGGTCGCCG
ACTTTTCGTTTCTCAAGGAGCTGATGATCAGCGAGATCGACGGCCCCTGCGATCACGCCTTCATTCTCGATGCCGAAGAC
ACGCTGTATGTCGAGTTGTTCGGCCTGCGCGAGGTGGCCCAGGCGGTGCGCCGCGACGCCCGGGCGGCGCCGGCGCTTTC
AGCCCAGGGATCGAAGATGTACGTCGTGCCCTTCGCCCCAACCGCCGAGAATCTGGCGGCCCATTGGCATGCCCTGCTGG
CCCCGCTGGTCAGCGCCCATGGCAAGGGGGGGATCTTTCTCGCGGCGGTGCGGGCCTTTGAAACGCCCAATTGCGAGGCG
ACCTTTCCCGCTCCCGGCCGCTTCTCCGTGATCGAGGAGGCGCCGCCGCGCCTTGCCGAACCGCTGGCCCTGGCCGCCTA
TCGAGACCACGCCTGA

Upstream 100 bases:

>100_bases
GCCGACGGCGCGCCGCGACGGGAGTTTTTCGAGGCCGTTCGCGCCTGACCGACGCGGCGCCTTGCGCCGTTTTCCATCTT
TCTGAGGTCGAGGTCAGCCA

Downstream 100 bases:

>100_bases
CAACACCGGTCGTTTCATGGCACAAAGGGGGATCCGCCAAGGTAACGCAGGACCGACGATGGCCGAAAAGCCCCCGCTTC
CCCCGAAAGACGTGCTGTTT

Product: hypothetical protein

Products: 6-pyruvoyl-5,6,7,8-tetrahydropterin; triphosphate

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MFEITRKIEIDAGHRIREHGSKCRNLHGHRYQIHVSVRSDQLVAGGSESGMVADFSFLKELMISEIDGPCDHAFILDAED
TLYVELFGLREVAQAVRRDARAAPALSAQGSKMYVVPFAPTAENLAAHWHALLAPLVSAHGKGGIFLAAVRAFETPNCEA
TFPAPGRFSVIEEAPPRLAEPLALAAYRDHA

Sequences:

>Translated_191_residues
MFEITRKIEIDAGHRIREHGSKCRNLHGHRYQIHVSVRSDQLVAGGSESGMVADFSFLKELMISEIDGPCDHAFILDAED
TLYVELFGLREVAQAVRRDARAAPALSAQGSKMYVVPFAPTAENLAAHWHALLAPLVSAHGKGGIFLAAVRAFETPNCEA
TFPAPGRFSVIEEAPPRLAEPLALAAYRDHA
>Mature_191_residues
MFEITRKIEIDAGHRIREHGSKCRNLHGHRYQIHVSVRSDQLVAGGSESGMVADFSFLKELMISEIDGPCDHAFILDAED
TLYVELFGLREVAQAVRRDARAAPALSAQGSKMYVVPFAPTAENLAAHWHALLAPLVSAHGKGGIFLAAVRAFETPNCEA
TFPAPGRFSVIEEAPPRLAEPLALAAYRDHA

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: 4.2.3.12

Molecular weight: Translated: 20840; Mature: 20840

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEITRKIEIDAGHRIREHGSKCRNLHGHRYQIHVSVRSDQLVAGGSESGMVADFSFLKE
CCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCEEEECCCCCCEEEHHHHHHH
LMISEIDGPCDHAFILDAEDTLYVELFGLREVAQAVRRDARAAPALSAQGSKMYVVPFAP
HHHHHCCCCCCCEEEEECCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
TAENLAAHWHALLAPLVSAHGKGGIFLAAVRAFETPNCEATFPAPGRFSVIEEAPPRLAE
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCCCCEECCCCCCEEECCCCCCHHHC
PLALAAYRDHA
HHHHHHHCCCC
>Mature Secondary Structure
MFEITRKIEIDAGHRIREHGSKCRNLHGHRYQIHVSVRSDQLVAGGSESGMVADFSFLKE
CCCEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCEEEECCCCCCEEEHHHHHHH
LMISEIDGPCDHAFILDAEDTLYVELFGLREVAQAVRRDARAAPALSAQGSKMYVVPFAP
HHHHHCCCCCCCEEEEECCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
TAENLAAHWHALLAPLVSAHGKGGIFLAAVRAFETPNCEATFPAPGRFSVIEEAPPRLAE
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCCCCEECCCCCCEEECCCCCCHHHC
PLALAAYRDHA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin

Specific reaction: 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin = 6-pyruvoyl-5,6,7,8-tetrahydropterin + triphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]