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The map label for this gene is nrdR

Identifier: 83593161

GI number: 83593161

Start: 2124708

End: 2125166

Strand: Reverse

Name: nrdR

Synonym: Rru_A1826

Alternate gene names: 83593161

Gene position: 2125166-2124708 (Counterclockwise)

Preceding gene: 83593162

Following gene: 83593160

Centisome position: 48.82

GC content: 62.53

Gene sequence:

>459_bases
ATGCGCTGCCCTTTCTGCGGCAACGGTGATACGCAGGTAAAAGATTCGCGCCCCACGGAGGACAGCGCCGCCATTCGACG
GCGGCGCTTCTGCCCGGCTTGCAACTCGCGCTTCACGACCTTCGAGCGGGTTCAGCTTCGCGATTTGGTGATCGTCAAGA
AAGACGGTCAGCGTTCGGCCTTCGACCGGGACAAGCTCGCCCGGTCGATCCGCATCGCCTGCCGCAAGCGCCCGGTCGAT
GAGGACAGCATCGAACGCATCGTCAACGGCATCCAACGCCGCCTGGAAAGCTCGGGCGATACCGAGATCAATTCCAAGGC
GGTGGGGGAACTGGTGATGGAAGGCCTGCGCGGCCTTGATCCCGTCGCCTATGTGCGCTTCGCCTCCGTCTACCGCAATT
TCCGCGAAGCCAAGGATTTCGAAGACTTCGTCGAGACCCTGGGCGGCTCGGCCGATTAA

Upstream 100 bases:

>100_bases
GTGCGCGAAAAGGTCGCCGTCCTTTGCCGTCGCTTTCCCATATATGGTGGGTTATAAGTCTTCAAGGAACACATCTTGAA
GACTGGGGAGGCTCCCCTCG

Downstream 100 bases:

>100_bases
CCCCGGTCGATCGCAGATGGCGTCTTCGGCCGATCTTTCCTTTATGCGCACCGCCCTGGGTCTGGCCGCCCGTGGCCTGG
GCCGGGTTTGGCCCAATCCG

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MRCPFCGNGDTQVKDSRPTEDSAAIRRRRFCPACNSRFTTFERVQLRDLVIVKKDGQRSAFDRDKLARSIRIACRKRPVD
EDSIERIVNGIQRRLESSGDTEINSKAVGELVMEGLRGLDPVAYVRFASVYRNFREAKDFEDFVETLGGSAD

Sequences:

>Translated_152_residues
MRCPFCGNGDTQVKDSRPTEDSAAIRRRRFCPACNSRFTTFERVQLRDLVIVKKDGQRSAFDRDKLARSIRIACRKRPVD
EDSIERIVNGIQRRLESSGDTEINSKAVGELVMEGLRGLDPVAYVRFASVYRNFREAKDFEDFVETLGGSAD
>Mature_152_residues
MRCPFCGNGDTQVKDSRPTEDSAAIRRRRFCPACNSRFTTFERVQLRDLVIVKKDGQRSAFDRDKLARSIRIACRKRPVD
EDSIERIVNGIQRRLESSGDTEINSKAVGELVMEGLRGLDPVAYVRFASVYRNFREAKDFEDFVETLGGSAD

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=47.1428571428571, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_RHORT (Q2RTB9)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426913.1
- STRING:   Q2RTB9
- GeneID:   3835250
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1826
- NMPDR:   fig|1085.1.peg.2401
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q2RTB9
- ProtClustDB:   PRK00464
- BioCyc:   RRUB269796:RRU_A1826-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17298; Mature: 17298

Theoretical pI: Translated: 8.77; Mature: 8.77

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGNGDTQVKDSRPTEDSAAIRRRRFCPACNSRFTTFERVQLRDLVIVKKDGQRSA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEECCCCCCCH
FDRDKLARSIRIACRKRPVDEDSIERIVNGIQRRLESSGDTEINSKAVGELVMEGLRGLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
PVAYVRFASVYRNFREAKDFEDFVETLGGSAD
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRCPFCGNGDTQVKDSRPTEDSAAIRRRRFCPACNSRFTTFERVQLRDLVIVKKDGQRSA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHEEEECCCCCCCH
FDRDKLARSIRIACRKRPVDEDSIERIVNGIQRRLESSGDTEINSKAVGELVMEGLRGLD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
PVAYVRFASVYRNFREAKDFEDFVETLGGSAD
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA