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The map label for this gene is hflX [H]

Identifier: 83593020

GI number: 83593020

Start: 1976698

End: 1977954

Strand: Direct

Name: hflX [H]

Synonym: Rru_A1685

Alternate gene names: 83593020

Gene position: 1976698-1977954 (Clockwise)

Preceding gene: 83593019

Following gene: 83593021

Centisome position: 45.41

GC content: 66.75

Gene sequence:

>1257_bases
GTGCTTCATCCTTTTCTCCGCAAGGGCCGTCCGGCCGCGCGGAGCCCCGAGGCTCGACTGGCCGAAGCCAACGGTCTGGC
CGAAGCGATTTCCCTGGATGTGGCCCTGTCGGAAACCGTGCCGATGGCCCGGGTGGTGCCGGCCACCTATATCGGTGGCG
GCGCGGTCGAACGCATGGCCGGGATCATCGCCGCCGAGGCGATTTCCCTGGTGGTCGTCGACACCCAGCTTTCCCCCATT
CAACAGCGCAACCTGGAACGGGCCTGGGCCTGCAAGGTCATCGACCGCACCGGCCTGATCCTCGAGATTTTCGGCGAGCG
CGCCCGCACGGCCGAAGGCCAGATGCAGGTTGAACTGGCCCATCTGACCTATCAGCGCTCGCGTCTGGTGCGCAGTTGGA
CCCATCTTGAGCGCCAGCGCGGCGGCGTCGGCTTTCTGGGCGGTCCGGGCGAAACCCAGATCGAGCTTGACCGCCGGCTG
ATCGGCGATCGCATCACCCGCCTGCGCAAGGACCTGGAAGAGGTGCGCCGCACCCGGGGATTGCACCGCGAAGCCCGCGC
CCGCGTGCCCTATCCGGTGGTGGCGCTGGTCGGCTATACCAATTCGGGCAAATCGACCCTGTTCAACCGCCTGACCGCCG
GCGGCGTTCTCGCCAAGGACATGCTGTTTGCCACCTTGGATCCGACGATGCGGTCCCTTGACCTGCCTTCGGGGCGCAAG
GTGATCTTGTCCGATACCGTCGGCTTCGTCTCCGACCTTCCCCACGAGTTGGTCGCGGCCTTCCGCGCCACCCTTGAAGA
GGTCAAGGCCGCCGATGTCATCGTTCATGTCCGCGATATCGCCGGCATCGACAGCGACGCCCAGAAGGCCGATGTCGAGG
TGGTCTTGCGCGAGATGGAGCTTGATGAACGGGTCGAAAGCGGCCTGATCGAGGCGCTGAACAAGATCGATCTGCTCGAT
TCGGAACGGCAGGCCCAGCTGGTCGAAGACACCGCGGGCCGCGACACCCTGGTGCCGGTCTCGGCGGTGACCGGGGCGGG
GACCGACGCGCTGTTGGCCCGCATCGACGCCCGTCTGGCCGAAAGCCGCATCGTTCTTGGCCTGTCCATTCCGCTGAGCG
ACGGCGCCACCCTGGCCTGGGTCTATCGCAAGGGCGAGGTTCTCGAGCGTCACGACGACGAGGAGCAGGCCCATCTCACC
GTTCGCCTCGATCCGGCCGATATCGGCCGCCTCGATCCGCGCCTGCGCACCCCCTGA

Upstream 100 bases:

>100_bases
TGCAACTGTTCGAACCCACCAAGGAAGAAGTCGAGGCCTGAGACACCCTTTGTCCGCTGATCACGATCAGGAAGGCCCGC
CGTCCGCATCCCGGGCGGCG

Downstream 100 bases:

>100_bases
CCACCGAAAAAAAGCCCCCTCCGCGCCCCGCCAAAACCGGGCGGGGAGGGGGCTTTTTCGTGCGAAAAACCACAGGATGT
GTGTTACGTCGCGCGGAATA

Product: small GTP-binding protein domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MLHPFLRKGRPAARSPEARLAEANGLAEAISLDVALSETVPMARVVPATYIGGGAVERMAGIIAAEAISLVVVDTQLSPI
QQRNLERAWACKVIDRTGLILEIFGERARTAEGQMQVELAHLTYQRSRLVRSWTHLERQRGGVGFLGGPGETQIELDRRL
IGDRITRLRKDLEEVRRTRGLHREARARVPYPVVALVGYTNSGKSTLFNRLTAGGVLAKDMLFATLDPTMRSLDLPSGRK
VILSDTVGFVSDLPHELVAAFRATLEEVKAADVIVHVRDIAGIDSDAQKADVEVVLREMELDERVESGLIEALNKIDLLD
SERQAQLVEDTAGRDTLVPVSAVTGAGTDALLARIDARLAESRIVLGLSIPLSDGATLAWVYRKGEVLERHDDEEQAHLT
VRLDPADIGRLDPRLRTP

Sequences:

>Translated_418_residues
MLHPFLRKGRPAARSPEARLAEANGLAEAISLDVALSETVPMARVVPATYIGGGAVERMAGIIAAEAISLVVVDTQLSPI
QQRNLERAWACKVIDRTGLILEIFGERARTAEGQMQVELAHLTYQRSRLVRSWTHLERQRGGVGFLGGPGETQIELDRRL
IGDRITRLRKDLEEVRRTRGLHREARARVPYPVVALVGYTNSGKSTLFNRLTAGGVLAKDMLFATLDPTMRSLDLPSGRK
VILSDTVGFVSDLPHELVAAFRATLEEVKAADVIVHVRDIAGIDSDAQKADVEVVLREMELDERVESGLIEALNKIDLLD
SERQAQLVEDTAGRDTLVPVSAVTGAGTDALLARIDARLAESRIVLGLSIPLSDGATLAWVYRKGEVLERHDDEEQAHLT
VRLDPADIGRLDPRLRTP
>Mature_418_residues
MLHPFLRKGRPAARSPEARLAEANGLAEAISLDVALSETVPMARVVPATYIGGGAVERMAGIIAAEAISLVVVDTQLSPI
QQRNLERAWACKVIDRTGLILEIFGERARTAEGQMQVELAHLTYQRSRLVRSWTHLERQRGGVGFLGGPGETQIELDRRL
IGDRITRLRKDLEEVRRTRGLHREARARVPYPVVALVGYTNSGKSTLFNRLTAGGVLAKDMLFATLDPTMRSLDLPSGRK
VILSDTVGFVSDLPHELVAAFRATLEEVKAADVIVHVRDIAGIDSDAQKADVEVVLREMELDERVESGLIEALNKIDLLD
SERQAQLVEDTAGRDTLVPVSAVTGAGTDALLARIDARLAESRIVLGLSIPLSDGATLAWVYRKGEVLERHDDEEQAHLT
VRLDPADIGRLDPRLRTP

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=278, Percent_Identity=38.4892086330935, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI310133116, Length=266, Percent_Identity=38.3458646616541, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI310124269, Length=245, Percent_Identity=38.7755102040816, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI310124267, Length=245, Percent_Identity=38.7755102040816, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI310124171, Length=245, Percent_Identity=38.7755102040816, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI310124169, Length=245, Percent_Identity=38.7755102040816, Blast_Score=162, Evalue=5e-40,
Organism=Escherichia coli, GI1790615, Length=367, Percent_Identity=44.4141689373297, Blast_Score=278, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=440, Percent_Identity=30, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24650079, Length=420, Percent_Identity=33.3333333333333, Blast_Score=164, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 45798; Mature: 45798

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHPFLRKGRPAARSPEARLAEANGLAEAISLDVALSETVPMARVVPATYIGGGAVERMA
CCCCCHHCCCCCCCCCCHHHHHHCCHHHHHEEEEEHHCCCCHHHHCCHHHCCCHHHHHHH
GIIAAEAISLVVVDTQLSPIQQRNLERAWACKVIDRTGLILEIFGERARTAEGQMQVELA
HHHHHHHEEEEEEECCCCCHHHHCCCHHHHHHHHCCCCCEEEECCCHHCCCCCCEEEEHH
HLTYQRSRLVRSWTHLERQRGGVGFLGGPGETQIELDRRLIGDRITRLRKDLEEVRRTRG
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LHREARARVPYPVVALVGYTNSGKSTLFNRLTAGGVLAKDMLFATLDPTMRSLDLPSGRK
CCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHCCCCCCCE
VILSDTVGFVSDLPHELVAAFRATLEEVKAADVIVHVRDIAGIDSDAQKADVEVVLREME
EEEECCHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCCCCHHHHHHHHHHHHH
LDERVESGLIEALNKIDLLDSERQAQLVEDTAGRDTLVPVSAVTGAGTDALLARIDARLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEHHHCCCCHHHHHHHHHHHHH
ESRIVLGLSIPLSDGATLAWVYRKGEVLERHDDEEQAHLTVRLDPADIGRLDPRLRTP
CCEEEEEEEEECCCCCEEEEEEECCCHHHCCCCCCCEEEEEEECHHCCCCCCCCCCCC
>Mature Secondary Structure
MLHPFLRKGRPAARSPEARLAEANGLAEAISLDVALSETVPMARVVPATYIGGGAVERMA
CCCCCHHCCCCCCCCCCHHHHHHCCHHHHHEEEEEHHCCCCHHHHCCHHHCCCHHHHHHH
GIIAAEAISLVVVDTQLSPIQQRNLERAWACKVIDRTGLILEIFGERARTAEGQMQVELA
HHHHHHHEEEEEEECCCCCHHHHCCCHHHHHHHHCCCCCEEEECCCHHCCCCCCEEEEHH
HLTYQRSRLVRSWTHLERQRGGVGFLGGPGETQIELDRRLIGDRITRLRKDLEEVRRTRG
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LHREARARVPYPVVALVGYTNSGKSTLFNRLTAGGVLAKDMLFATLDPTMRSLDLPSGRK
CCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHCCCCCCCE
VILSDTVGFVSDLPHELVAAFRATLEEVKAADVIVHVRDIAGIDSDAQKADVEVVLREME
EEEECCHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCCCCHHHHHHHHHHHHH
LDERVESGLIEALNKIDLLDSERQAQLVEDTAGRDTLVPVSAVTGAGTDALLARIDARLA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEHHHCCCCHHHHHHHHHHHHH
ESRIVLGLSIPLSDGATLAWVYRKGEVLERHDDEEQAHLTVRLDPADIGRLDPRLRTP
CCEEEEEEEEECCCCCEEEEEEECCCHHHCCCCCCCEEEEEEECHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]