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The map label for this gene is nuoN [H]

Identifier: 83592970

GI number: 83592970

Start: 1926486

End: 1927994

Strand: Reverse

Name: nuoN [H]

Synonym: Rru_A1635

Alternate gene names: 83592970

Gene position: 1927994-1926486 (Counterclockwise)

Preceding gene: 83592971

Following gene: 83592969

Centisome position: 44.29

GC content: 64.55

Gene sequence:

>1509_bases
ATGATACCCACCCATCTGCCGATCTTGCAGGTCGTCGTGCCGCTGATGGCGGCGCCGGTGTGCATCCTGCTGCGCCGCCC
CGGTTTGTGCTGGGCCTGGGCGCTGCTGATCGCCTTGACCACCTTGACGATGGCGGTTGGCCTGCTGGCCGGGGTTTTGA
CCCACGGGCCCAGCGCCTATCACCTTGGCGATTGGTCGCCGCCCTGGGGGATCGAACTGCATGTCGATCTGCTGAGCGCA
CTGGTTCTGGTTCTGGTCACCGCCACCGCCAGTTTGGTGATCGTTTATGCCCGCGCCAGTTTCGCCGCGGAAATCGACCC
CGGCCACCATACCCTGGCCTATTGCCTGTTCTTGCTCTGCCTGACCGGGCTTTTGGGCATGGCGATCACCGGCGACGCCT
TCAACTTGTTCGTTTTCCTTGAGATATCAAGCCTGTCGTCCTATGCCCTGGTCGCCCTCGGCCGCGATCGCCGGGCCCTT
TACGCTGCCTATCATTATCTGATCCTGGGCACGGTGGGGGCGACCTTCTACGTCATCGGCATCGGCTTTTTGTACATGAT
GACCGGCACGCTCAACATGAACGATCTCGCCCAAAGATTGCCCGCCGTCGCCCATAGCCGCACGGCGGTGGCCGGGGTGG
TGTTCTTAGGGGTCGGGCTGTCGCTGAAGTTGGCGCTGTTTCCGCTGCATAAATGGCTTCCCGCCGCCTACAGCTATGCG
CCAAGCGCCGTTGGCGCCTTTCTGGCGGCGACGTCGACCAAGGTCGCCTTTTATGTCATGGTCCGGCTGTTTCTGGGCGT
GCTGGCCCCGGCTTTTTCGGCCAACCTGCTGCCCGGCCCGGTCAGTGCGCGCGAGATGGTGATGGTTCTGGCGCTGGCAG
CCATCCTCAGCGGGTCGTTCAGCGCCATTTTCCAAAGCGACGCCAAACGTTTGCTGGCCTATTCCTCGGTCTCGCAAATT
GGCGTCATGGTGCTTGGCCTTAGCCTGTTCAGCCTTGATGGCGTCGCCGGCGGCCTTGTTCATATGCTCAACCACGCCCT
GATCAAGGCCAGCTTGTTCATGGCCCTGGGCTGCGTCTTCCTGCGCATCGGCTCGGTCGAGATCGCCGATATGGCCGGCA
TCGGCCGGCGCATGCCGTGGACGATGGCCGCCTTCGTCATCGGCGGGCTGTCGCTGATCGGCATCCCCGGCACCGCCGGC
TTCATCAGCAAATGGCAGCTGGCGCAGAGCGCCATCGCCGAGGGCTGGTGGCTGGCGGTCGCCGCCCTGATCGCCAGTTC
CCTGCTGGCGGTCGTCTATGTCGGCAAGGTGATCGAGGCCGCCTATTTCCGCCCCTCGCCCGCCGAGTCCCCCTCTGGCG
CCCCCTCTGCCCCCCAAGAGGCGCCGGCCATGATGCTGGCGCCCCTGTGGATCGCCGCCCTGGCCAATATCGGCTTTGGC
CTGAACACCACCTGGACCCTGGGGCTGGCCAAACGCGCGGCGTCGGCCCTGATGGGACTCCCCTCATGA

Upstream 100 bases:

>100_bases
CCACCACCGCCCTCGGGCTGGCCCTGGTGGTGCGCATCAAGGAAGCCTTCGGCACCATCGAGGAAGACGAGATCGGCCAG
AGCCTCACCGGGATGGGCCG

Downstream 100 bases:

>100_bases
GCGCCGCCCCCGCCCTGTCGCTGGCCTGGATCCTTGCCACGCCGCTGGCCGCCACCCTGGTGATCGCCTTGAACGCCAAG
CGCCCGCGCCTGGGCGAGGC

Product: putative monovalent cation/H+ antiporter subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MIPTHLPILQVVVPLMAAPVCILLRRPGLCWAWALLIALTTLTMAVGLLAGVLTHGPSAYHLGDWSPPWGIELHVDLLSA
LVLVLVTATASLVIVYARASFAAEIDPGHHTLAYCLFLLCLTGLLGMAITGDAFNLFVFLEISSLSSYALVALGRDRRAL
YAAYHYLILGTVGATFYVIGIGFLYMMTGTLNMNDLAQRLPAVAHSRTAVAGVVFLGVGLSLKLALFPLHKWLPAAYSYA
PSAVGAFLAATSTKVAFYVMVRLFLGVLAPAFSANLLPGPVSAREMVMVLALAAILSGSFSAIFQSDAKRLLAYSSVSQI
GVMVLGLSLFSLDGVAGGLVHMLNHALIKASLFMALGCVFLRIGSVEIADMAGIGRRMPWTMAAFVIGGLSLIGIPGTAG
FISKWQLAQSAIAEGWWLAVAALIASSLLAVVYVGKVIEAAYFRPSPAESPSGAPSAPQEAPAMMLAPLWIAALANIGFG
LNTTWTLGLAKRAASALMGLPS

Sequences:

>Translated_502_residues
MIPTHLPILQVVVPLMAAPVCILLRRPGLCWAWALLIALTTLTMAVGLLAGVLTHGPSAYHLGDWSPPWGIELHVDLLSA
LVLVLVTATASLVIVYARASFAAEIDPGHHTLAYCLFLLCLTGLLGMAITGDAFNLFVFLEISSLSSYALVALGRDRRAL
YAAYHYLILGTVGATFYVIGIGFLYMMTGTLNMNDLAQRLPAVAHSRTAVAGVVFLGVGLSLKLALFPLHKWLPAAYSYA
PSAVGAFLAATSTKVAFYVMVRLFLGVLAPAFSANLLPGPVSAREMVMVLALAAILSGSFSAIFQSDAKRLLAYSSVSQI
GVMVLGLSLFSLDGVAGGLVHMLNHALIKASLFMALGCVFLRIGSVEIADMAGIGRRMPWTMAAFVIGGLSLIGIPGTAG
FISKWQLAQSAIAEGWWLAVAALIASSLLAVVYVGKVIEAAYFRPSPAESPSGAPSAPQEAPAMMLAPLWIAALANIGFG
LNTTWTLGLAKRAASALMGLPS
>Mature_502_residues
MIPTHLPILQVVVPLMAAPVCILLRRPGLCWAWALLIALTTLTMAVGLLAGVLTHGPSAYHLGDWSPPWGIELHVDLLSA
LVLVLVTATASLVIVYARASFAAEIDPGHHTLAYCLFLLCLTGLLGMAITGDAFNLFVFLEISSLSSYALVALGRDRRAL
YAAYHYLILGTVGATFYVIGIGFLYMMTGTLNMNDLAQRLPAVAHSRTAVAGVVFLGVGLSLKLALFPLHKWLPAAYSYA
PSAVGAFLAATSTKVAFYVMVRLFLGVLAPAFSANLLPGPVSAREMVMVLALAAILSGSFSAIFQSDAKRLLAYSSVSQI
GVMVLGLSLFSLDGVAGGLVHMLNHALIKASLFMALGCVFLRIGSVEIADMAGIGRRMPWTMAAFVIGGLSLIGIPGTAG
FISKWQLAQSAIAEGWWLAVAALIASSLLAVVYVGKVIEAAYFRPSPAESPSGAPSAPQEAPAMMLAPLWIAALANIGFG
LNTTWTLGLAKRAASALMGLPS

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=330, Percent_Identity=24.2424242424242, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1788831, Length=358, Percent_Identity=29.0502793296089, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1788827, Length=360, Percent_Identity=28.0555555555556, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI145693160, Length=374, Percent_Identity=29.9465240641711, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788613, Length=426, Percent_Identity=27.9342723004695, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788829, Length=363, Percent_Identity=28.3746556473829, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788614, Length=364, Percent_Identity=29.3956043956044, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI2367154, Length=297, Percent_Identity=26.9360269360269, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52666; Mature: 52666

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPTHLPILQVVVPLMAAPVCILLRRPGLCWAWALLIALTTLTMAVGLLAGVLTHGPSAY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HLGDWSPPWGIELHVDLLSALVLVLVTATASLVIVYARASFAAEIDPGHHTLAYCLFLLC
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHEEEEHHHHHEECCCCHHHHHHHHHHHH
LTGLLGMAITGDAFNLFVFLEISSLSSYALVALGRDRRALYAAYHYLILGTVGATFYVIG
HHHHHHHEECCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
IGFLYMMTGTLNMNDLAQRLPAVAHSRTAVAGVVFLGVGLSLKLALFPLHKWLPAAYSYA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
PSAVGAFLAATSTKVAFYVMVRLFLGVLAPAFSANLLPGPVSAREMVMVLALAAILSGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCH
SAIFQSDAKRLLAYSSVSQIGVMVLGLSLFSLDGVAGGLVHMLNHALIKASLFMALGCVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRIGSVEIADMAGIGRRMPWTMAAFVIGGLSLIGIPGTAGFISKWQLAQSAIAEGWWLAV
HHHCCEEEHHHHCCCCCCCHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AALIASSLLAVVYVGKVIEAAYFRPSPAESPSGAPSAPQEAPAMMLAPLWIAALANIGFG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
LNTTWTLGLAKRAASALMGLPS
CCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIPTHLPILQVVVPLMAAPVCILLRRPGLCWAWALLIALTTLTMAVGLLAGVLTHGPSAY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HLGDWSPPWGIELHVDLLSALVLVLVTATASLVIVYARASFAAEIDPGHHTLAYCLFLLC
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHEEEEHHHHHEECCCCHHHHHHHHHHHH
LTGLLGMAITGDAFNLFVFLEISSLSSYALVALGRDRRALYAAYHYLILGTVGATFYVIG
HHHHHHHEECCCCEEEEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
IGFLYMMTGTLNMNDLAQRLPAVAHSRTAVAGVVFLGVGLSLKLALFPLHKWLPAAYSYA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
PSAVGAFLAATSTKVAFYVMVRLFLGVLAPAFSANLLPGPVSAREMVMVLALAAILSGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCH
SAIFQSDAKRLLAYSSVSQIGVMVLGLSLFSLDGVAGGLVHMLNHALIKASLFMALGCVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LRIGSVEIADMAGIGRRMPWTMAAFVIGGLSLIGIPGTAGFISKWQLAQSAIAEGWWLAV
HHHCCEEEHHHHCCCCCCCHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AALIASSLLAVVYVGKVIEAAYFRPSPAESPSGAPSAPQEAPAMMLAPLWIAALANIGFG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
LNTTWTLGLAKRAASALMGLPS
CCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA