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The map label for this gene is fabZ [H]

Identifier: 83592931

GI number: 83592931

Start: 1881099

End: 1881593

Strand: Direct

Name: fabZ [H]

Synonym: Rru_A1596

Alternate gene names: 83592931

Gene position: 1881099-1881593 (Clockwise)

Preceding gene: 83592930

Following gene: 83592932

Centisome position: 43.22

GC content: 60.0

Gene sequence:

>495_bases
ATGACAGAGACGGTGCAGGCGGATCCGCAGGAAAACCAGGTTCGGACGACGGTCGATATCGCACGGATTATCGATATGAT
TCCGCACCGTTATCCCTTCTTGATGGTCGACAAGTTGATCGACATGGTGCGCGGTGAAAGCGCCATCGGCATCAAGAACG
TGACGATCAACGAGCCCTTCTTCCAGGGCCATTTCCCCAATCGACCCGTGATGCCCGGCGTGCTGATCGTCGAGGCGATG
GCGCAGACCGCCGCCGTTCTGGTGGTTGAAACCCTTGGGGTGCGGGCCGAGGGCAAGATCGTCTATTTCATGATCGTCGA
GAACGCCCGCTTCCGCAAACCGGTGATTCCGGGGGATCAGCTGCGCCTGCATGTCGCGAAGGAACGTCATCGCGGCAATG
TGTGGAAGTTCCGCGGCGTGGCCAAGGTCGACGAGGTCGTTGTCGCCGAGGCGACCTTCGCGGCGATGATCATGGACGAA
GAGCCCCAGCCCTAA

Upstream 100 bases:

>100_bases
GGCCCGGCGGCAAAGCCGGGGCTCCCAACGACTTTGGGAAGGCGTCGGCATTGGGGGCACCAAGCGAACGCGCCGCTTCC
GTGGAATGGGACGATTGGGC

Downstream 100 bases:

>100_bases
TCCCCCCTATCCTTGAGAGCCTGCCCCATTATGCCGAGCATTCATCCGACCGCGATCGTCGACCCCAAGGCCGACCTTGG
CCACTCCGTTTCCATCGGCC

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTETVQADPQENQVRTTVDIARIIDMIPHRYPFLMVDKLIDMVRGESAIGIKNVTINEPFFQGHFPNRPVMPGVLIVEAM
AQTAAVLVVETLGVRAEGKIVYFMIVENARFRKPVIPGDQLRLHVAKERHRGNVWKFRGVAKVDEVVVAEATFAAMIMDE
EPQP

Sequences:

>Translated_164_residues
MTETVQADPQENQVRTTVDIARIIDMIPHRYPFLMVDKLIDMVRGESAIGIKNVTINEPFFQGHFPNRPVMPGVLIVEAM
AQTAAVLVVETLGVRAEGKIVYFMIVENARFRKPVIPGDQLRLHVAKERHRGNVWKFRGVAKVDEVVVAEATFAAMIMDE
EPQP
>Mature_163_residues
TETVQADPQENQVRTTVDIARIIDMIPHRYPFLMVDKLIDMVRGESAIGIKNVTINEPFFQGHFPNRPVMPGVLIVEAMA
QTAAVLVVETLGVRAEGKIVYFMIVENARFRKPVIPGDQLRLHVAKERHRGNVWKFRGVAKVDEVVVAEATFAAMIMDEE
PQP

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=136, Percent_Identity=47.7941176470588, Blast_Score=150, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 18477; Mature: 18346

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETVQADPQENQVRTTVDIARIIDMIPHRYPFLMVDKLIDMVRGESAIGIKNVTINEPF
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCE
FQGHFPNRPVMPGVLIVEAMAQTAAVLVVETLGVRAEGKIVYFMIVENARFRKPVIPGDQ
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCC
LRLHVAKERHRGNVWKFRGVAKVDEVVVAEATFAAMIMDEEPQP
EEEEEEHHCCCCCEEEECCCCHHHHHHHHHHHEEEEEECCCCCC
>Mature Secondary Structure 
TETVQADPQENQVRTTVDIARIIDMIPHRYPFLMVDKLIDMVRGESAIGIKNVTINEPF
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCE
FQGHFPNRPVMPGVLIVEAMAQTAAVLVVETLGVRAEGKIVYFMIVENARFRKPVIPGDQ
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCC
LRLHVAKERHRGNVWKFRGVAKVDEVVVAEATFAAMIMDEEPQP
EEEEEEHHCCCCCEEEECCCCHHHHHHHHHHHEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA