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The map label for this gene is nuoL [H]

Identifier: 83592901

GI number: 83592901

Start: 1845549

End: 1847480

Strand: Direct

Name: nuoL [H]

Synonym: Rru_A1566

Alternate gene names: 83592901

Gene position: 1845549-1847480 (Clockwise)

Preceding gene: 83592900

Following gene: 83592902

Centisome position: 42.4

GC content: 63.46

Gene sequence:

>1932_bases
ATGCTGTATTTTCTCGCCGTCTTCCTGCCGCTTCTGACCGCCATCGCCACCGGCTTCTTCGGCCGGGCGCTTGGCGACAA
GGGGGCTCAGCGCCTGACCTGCCTGGGAATGGCGATTTCCGCCCTGTTCAGCTGGTTCATCTTTTTCGATACCGCCCTTG
GCGGCAACAATACCACCGTCACCTTGTTCACCTGGGTGATCTCCGGTGACCTGCACTTCGACTGGGCCTTGAAAATCGAT
ACCCTGTCGGCGGTGATGCTGATGGTGGTGACGACGATCTCGTTCATGGTCCACATCTATTCCGTGGGCTACATGCACCA
TGACGCCAGCGTGCCGCGCTTCATGGCCTATCTGTCGCTGTTCACCTTCTTCATGCTGATGCTGGTGACCGCCGATAATC
TGGTGCAGATGTTCTTCGGTTGGGAGGGCGTCGGGCTCGCCTCTTATCTGCTGATCGGTTTCTGGTACGAGAAACCCAGC
GCCAACGCGGCGGCGATCAAGGCTTTCGTCGTCAACCGTGTCGGCGATTTCGGCTTCACCCTGGGCATCTTCGGCGTCTT
CTTCGTTTTCGGCACCGTCGGCCTCGACGCCATTTTCGCCGGCGCCGCCCAGCATGCCAATGATGTCGTGACCTTCTTCG
GCATCGAATGGCACGCCATGACCATCTTGTGCCTGCTGCTGTTCATCGGTGCCATGGGCAAATCGGCCCAGCTTGGCCTG
CATACTTGGCTGCCCGACGCCATGGAGGGTCCGACCCCGGTTTCGGCGCTGATCCACGCCGCGACCATGGTCACCGCCGG
CGTCTTCATGGTAGCGCGGATGTCGCCGCTGTTCGTGCTGTCGGATACGGCGATGACCGTGGTCACCATCGTCGGCGCCT
CGACGGCGATCTTCGCCGCCACCGTCGGCTGCGTTCAGAACGACATCAAGCGGGTGATCGCCTATTCGACCTGCTCGCAG
CTTGGCTATATGTTCTTCGCGCTTGGTGTTGGCGCCTTCGGCGCGGGCATCTTCCATCTGATGACCCACGCCTTCTTCAA
GGCGCTGCTGTTCCTTGGCGCCGGCTCGGTCATCCACGCCATGTCCGACGAACAGGACATGCGCCGCATGGGCGGCATCT
GGCGGATGGTGCCGCTGACCTACGCCTTGATGTGGATCGGCTCGCTGGCCCTGATGGGCGTGCCGCCCTTCGCCGGCTTC
TTCTCCAAGGACATGATCCTTGAGGTCGCCTATGCCGCCCATGGCGGGGCGGGGGCCTATGCCTTCTGGCTGGGCATTCT
GGCGGCGACCCTGACGGCGTTTTATTCGACCCGCCTGATCATCATGACCTTCCATGGGGCGCCGCGGGCCGATGAGCATG
TGATGGCCCATGTCCACGAAAGCCCGCGGGTGATGACCCTGCCGCTGATCGTTCTGGCGATCGGCGCGGTGGTCGCCGGA
GGGCTGGGCGCCGACGCCTTCATCGGCGACGGACGCTTCGCCTTCTGGGGGACGGCGATCGCCCAGAGCGCCGAGGATGT
CACCCACCACGCCCACGACGTTCCGGGCTGGGTGAAGCTGTTGCCCCTGGTGGTGACGGCGCTGGGCGTCGGCCTGGGCG
TGTTCCTCTACGGTGTGCGGCCGAAACTGCCGGCCAAACTGGCCGCCTCGGCCCCCGGGCTTTACCGCTTCCTGCTCAAC
AAGTGGTATTTCGACGAACTTTACGACCGCATCTTCATCAAGCCCGCCTTCCTGCTTGGGCGCGGCTTCTGGAAGGACGG
TGACGGCGCCATCATCGACGGTGTCGGCCCCGACGGCGTGGCCTCGGCCACCCGGTCGCTGGCCCGGTGGTTCGGCAGGA
TGCAGACCGGCTATCTTTACCACTATGCCTTCGCGATGATCACCGGCATTGCCGGGGTCGTCACCTGGGTCATGGTCACC
TCCGCCCACTGA

Upstream 100 bases:

>100_bases
GCCGAGGCGGGCATCGGTTTGGCGATCGTCGTGGTCTTCTTCCGGAACCGCGGCTCGATCGAGGTCGAAGACATCAATCA
GATGAAGGGGTGACGGGGCA

Downstream 100 bases:

>100_bases
AAGAGGCCGTGATGAACGCCCTTCCGTTGCTTTCGATCATCACCTTCCTGCCGCTTGTCGGCGCGGTCTTCATCTTGACG
GTGAAGGGCGAGGAGGCGGT

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MLYFLAVFLPLLTAIATGFFGRALGDKGAQRLTCLGMAISALFSWFIFFDTALGGNNTTVTLFTWVISGDLHFDWALKID
TLSAVMLMVVTTISFMVHIYSVGYMHHDASVPRFMAYLSLFTFFMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPS
ANAAAIKAFVVNRVGDFGFTLGIFGVFFVFGTVGLDAIFAGAAQHANDVVTFFGIEWHAMTILCLLLFIGAMGKSAQLGL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFVLSDTAMTVVTIVGASTAIFAATVGCVQNDIKRVIAYSTCSQ
LGYMFFALGVGAFGAGIFHLMTHAFFKALLFLGAGSVIHAMSDEQDMRRMGGIWRMVPLTYALMWIGSLALMGVPPFAGF
FSKDMILEVAYAAHGGAGAYAFWLGILAATLTAFYSTRLIIMTFHGAPRADEHVMAHVHESPRVMTLPLIVLAIGAVVAG
GLGADAFIGDGRFAFWGTAIAQSAEDVTHHAHDVPGWVKLLPLVVTALGVGLGVFLYGVRPKLPAKLAASAPGLYRFLLN
KWYFDELYDRIFIKPAFLLGRGFWKDGDGAIIDGVGPDGVASATRSLARWFGRMQTGYLYHYAFAMITGIAGVVTWVMVT
SAH

Sequences:

>Translated_643_residues
MLYFLAVFLPLLTAIATGFFGRALGDKGAQRLTCLGMAISALFSWFIFFDTALGGNNTTVTLFTWVISGDLHFDWALKID
TLSAVMLMVVTTISFMVHIYSVGYMHHDASVPRFMAYLSLFTFFMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPS
ANAAAIKAFVVNRVGDFGFTLGIFGVFFVFGTVGLDAIFAGAAQHANDVVTFFGIEWHAMTILCLLLFIGAMGKSAQLGL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFVLSDTAMTVVTIVGASTAIFAATVGCVQNDIKRVIAYSTCSQ
LGYMFFALGVGAFGAGIFHLMTHAFFKALLFLGAGSVIHAMSDEQDMRRMGGIWRMVPLTYALMWIGSLALMGVPPFAGF
FSKDMILEVAYAAHGGAGAYAFWLGILAATLTAFYSTRLIIMTFHGAPRADEHVMAHVHESPRVMTLPLIVLAIGAVVAG
GLGADAFIGDGRFAFWGTAIAQSAEDVTHHAHDVPGWVKLLPLVVTALGVGLGVFLYGVRPKLPAKLAASAPGLYRFLLN
KWYFDELYDRIFIKPAFLLGRGFWKDGDGAIIDGVGPDGVASATRSLARWFGRMQTGYLYHYAFAMITGIAGVVTWVMVT
SAH
>Mature_643_residues
MLYFLAVFLPLLTAIATGFFGRALGDKGAQRLTCLGMAISALFSWFIFFDTALGGNNTTVTLFTWVISGDLHFDWALKID
TLSAVMLMVVTTISFMVHIYSVGYMHHDASVPRFMAYLSLFTFFMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPS
ANAAAIKAFVVNRVGDFGFTLGIFGVFFVFGTVGLDAIFAGAAQHANDVVTFFGIEWHAMTILCLLLFIGAMGKSAQLGL
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFVLSDTAMTVVTIVGASTAIFAATVGCVQNDIKRVIAYSTCSQ
LGYMFFALGVGAFGAGIFHLMTHAFFKALLFLGAGSVIHAMSDEQDMRRMGGIWRMVPLTYALMWIGSLALMGVPPFAGF
FSKDMILEVAYAAHGGAGAYAFWLGILAATLTAFYSTRLIIMTFHGAPRADEHVMAHVHESPRVMTLPLIVLAIGAVVAG
GLGADAFIGDGRFAFWGTAIAQSAEDVTHHAHDVPGWVKLLPLVVTALGVGLGVFLYGVRPKLPAKLAASAPGLYRFLLN
KWYFDELYDRIFIKPAFLLGRGFWKDGDGAIIDGVGPDGVASATRSLARWFGRMQTGYLYHYAFAMITGIAGVVTWVMVT
SAH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=482, Percent_Identity=38.7966804979253, Blast_Score=317, Evalue=2e-86,
Organism=Escherichia coli, GI1788614, Length=586, Percent_Identity=42.4914675767918, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1788829, Length=364, Percent_Identity=34.0659340659341, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1788831, Length=354, Percent_Identity=30.5084745762712, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1788827, Length=433, Percent_Identity=27.2517321016166, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI2367154, Length=212, Percent_Identity=29.2452830188679, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788613, Length=287, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI145693160, Length=309, Percent_Identity=26.2135922330097, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 69479; Mature: 69479

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYFLAVFLPLLTAIATGFFGRALGDKGAQRLTCLGMAISALFSWFIFFDTALGGNNTTV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TLFTWVISGDLHFDWALKIDTLSAVMLMVVTTISFMVHIYSVGYMHHDASVPRFMAYLSL
EEEEEEEECCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FTFFMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPSANAAAIKAFVVNRVGDFGFT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHHH
LGIFGVFFVFGTVGLDAIFAGAAQHANDVVTFFGIEWHAMTILCLLLFIGAMGKSAQLGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCH
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFVLSDTAMTVVTIVGASTAIFAA
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHHHH
TVGCVQNDIKRVIAYSTCSQLGYMFFALGVGAFGAGIFHLMTHAFFKALLFLGAGSVIHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
MSDEQDMRRMGGIWRMVPLTYALMWIGSLALMGVPPFAGFFSKDMILEVAYAAHGGAGAY
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHH
AFWLGILAATLTAFYSTRLIIMTFHGAPRADEHVMAHVHESPRVMTLPLIVLAIGAVVAG
HHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHC
GLGADAFIGDGRFAFWGTAIAQSAEDVTHHAHDVPGWVKLLPLVVTALGVGLGVFLYGVR
CCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PKLPAKLAASAPGLYRFLLNKWYFDELYDRIFIKPAFLLGRGFWKDGDGAIIDGVGPDGV
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHH
ASATRSLARWFGRMQTGYLYHYAFAMITGIAGVVTWVMVTSAH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLYFLAVFLPLLTAIATGFFGRALGDKGAQRLTCLGMAISALFSWFIFFDTALGGNNTTV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
TLFTWVISGDLHFDWALKIDTLSAVMLMVVTTISFMVHIYSVGYMHHDASVPRFMAYLSL
EEEEEEEECCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FTFFMLMLVTADNLVQMFFGWEGVGLASYLLIGFWYEKPSANAAAIKAFVVNRVGDFGFT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHCCHHHH
LGIFGVFFVFGTVGLDAIFAGAAQHANDVVTFFGIEWHAMTILCLLLFIGAMGKSAQLGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCH
HTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPLFVLSDTAMTVVTIVGASTAIFAA
HHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCHHHHHHH
TVGCVQNDIKRVIAYSTCSQLGYMFFALGVGAFGAGIFHLMTHAFFKALLFLGAGSVIHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
MSDEQDMRRMGGIWRMVPLTYALMWIGSLALMGVPPFAGFFSKDMILEVAYAAHGGAGAY
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHH
AFWLGILAATLTAFYSTRLIIMTFHGAPRADEHVMAHVHESPRVMTLPLIVLAIGAVVAG
HHHHHHHHHHHHHHHHCEEEEEEECCCCCCCHHHHHHHCCCCCEEHHHHHHHHHHHHHHC
GLGADAFIGDGRFAFWGTAIAQSAEDVTHHAHDVPGWVKLLPLVVTALGVGLGVFLYGVR
CCCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
PKLPAKLAASAPGLYRFLLNKWYFDELYDRIFIKPAFLLGRGFWKDGDGAIIDGVGPDGV
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHH
ASATRSLARWFGRMQTGYLYHYAFAMITGIAGVVTWVMVTSAH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]