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The map label for this gene is cheA [H]

Identifier: 83592735

GI number: 83592735

Start: 1650869

End: 1652950

Strand: Direct

Name: cheA [H]

Synonym: Rru_A1399

Alternate gene names: 83592735

Gene position: 1650869-1652950 (Clockwise)

Preceding gene: 83592734

Following gene: 83592736

Centisome position: 37.93

GC content: 63.69

Gene sequence:

>2082_bases
ATGACCCCCATGGACCCATCGGAGACCTTCCGCCAGGAAGCTCAGGAGTTGCTCGAACAGCTCGAGCAGGCTTTGCTTGA
CCTTGAACACGCCCCCGACGACGGCGATTTGATCGACAGCGCCTTTCGCGCCCTGCATACGATCAAGGGCTCGGGGTCGA
TGTTCGGCTTCGATGCGGTCGCCGCCTTTACCCATCACGTCGAAACCGCTTTCGATCTGGTGCGCAAAGGCAAGGTCACA
CCCAGCCGCGAGTTGATCGCCGTTGCCTTGGCGGCCAAGGATCGGATGCGGCTGTTGATCGAGCAACCCGAGACGCCCGA
GAGCGCCGAGGGCGACGCCATCTTGCGCGATCTCAAGGCCATCGTTGACGCCTCGGACCTTCCCTCGGCCGGCGAAGGAG
GGGACGCGCCGGTGGCGGCCAGGGAACAACCGGCCGAGATCACCTGGCGCATCCGCTTCCGTCTGGCGCGCGACGCGATG
GCGATGGGCACCAATCCTTTGCTGTTGCTTGATGAATTGCGCACCCTCGGCTCGGCGACCATCGTGGCGCTGACCGGGGA
GGTGCCTTCGCTCGAGGTTCTGGTTCCCAGCGACTGCCATCTCGCCTGGGATGTCATGCTGACGACCAGCCAGCCGCGCA
CGGCGATCGAAGACGTTTTCATGTTCGTCATCGATGACATGGAGTTGTCGATCGATCTTCTCGAGAGCGGCGAGGAGGAT
CGTCGCATCGGCGAGATCCTGGTCGAACGCGGCGATGTTGCCCAGGAGGCGGTCGATACGGCGGTGTCGCGGCAGTTGCC
GCTTGGTACCTTGCTTGTCGAGTCGGGTAATCTCAGCCCCGATAAGCTGACCTCGGCCCTGGCCGAGCAGCAGCATCTGC
GCACGGAAACCAAGGTTGTCGCCAAGGGCGCCGACAGCATCCGGGTTCCCGCCGAGCGTCTGGATGAACTGATGGATCGG
GTGGGGGAACTGGTGATCGCGCAGTCGCGGTTGACCCAGGTCGCCGCCTCGATCAACGACATGCAGGTCAAGGCGATCGC
CGAGGAAATCGAGCGGCTGGCCCATGAATTGCGCGATACCACCATGGGCGTGCGCATGGTGCCGATCAGTTCGCTGTTCG
GCCGCTTCCGCCGCCTTGTCCATGATCTCGCCCATGACCTGGGCAAGCAGATCGAATTGACCACCTTCGGCGAAGAGACC
GAACTCGATAAAACGGTGATCGAGCGTCTCAATGATCCGTTGATCCATCTTATCCGCAATTCCATCGATCACGGGCTGGA
AACCCCCGAGGGACGCAAGGAGGCGGGCAAGCCGCCGGCCGGGCGCATCACCTTGTCGGCGCGCCATTCCGGGGCCGAGG
TGCTGGTGTCGATCATCGATGATGGGCGCGGTCTCGACCGCGCCCGCATCCAGGCCCGCGCCGAAGAGCAGGGGCTGCTG
GCGCCGGGGGTGAAGCTTTCGGATAACGACCTGTTCCAGGTGATCTTCCAGGCCGGCTTCTCGACGGCCAAGGTGGTGAC
CAGCCTGTCGGGGCGTGGCGTCGGCATGGATGTGGTCAAACGCACCATCGAAGGCCTGCGCGGCAAGATCGACATCGCCA
GCACCCCGGGCAAGGGGACCGAACTGACCCTGCGGCTGCCGCTGACCCTGGCGATCATCGATGGCCTTCTGGTGCGCGTC
GGCAAGGCCCGCTATGTGCTGCCGCTGTCGGCCGTTGAAGAATGCGTCGAGCTGTCGGCCGAGGAGGACGGCCGCTCGCG
GGGGCGCAGCTTCCTGAATATCCGCGGCGATCTGGTGCCCTTCCTGCGCTTGCGCGAATTGTTCCAGGTGAGCGCCCCGG
CCGATCCCTATCAAAAGGTGGTCATCGTCTCTTCGGGCGAATTCCGGGTCGGGCTGGTGGTCGATCAGGTGATCGGCAAT
CACCAGACGGTGATCAAATCGCTTTCGAAGCTTCACGCCGACGTCGAGACCTTTTCCGGCGCCACCATCCTGGGCGATGG
CGCCGTCGCCCTGATTTTGGATATCGGCCATCTGGTCAAGCTCGGGCTGACTTACGAAAGCCAGTTCATGGCCGCCGGCT
GA

Upstream 100 bases:

>100_bases
CGATGAAGCAGGAGGCCAAGGTCGCCGGCGCGACCGGTTGGATCACCAAGCCGTTCCAGCAAGAGCAGCTGGTCACCGTG
GTGCGTAAGGTGCTCGGCGC

Downstream 100 bases:

>100_bases
CGGCAAACCCCAGTCATCGGCGCGCCCTTTTTCCGAAAGACGCGCGCAAGGGAGAAGTGTCGACATGTCTCTTTGGAATG
GTGGTCGGTCGCTCGAGGTC

Product: CheA Signal transduction histidine Kinases (STHK)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 692

Protein sequence:

>693_residues
MTPMDPSETFRQEAQELLEQLEQALLDLEHAPDDGDLIDSAFRALHTIKGSGSMFGFDAVAAFTHHVETAFDLVRKGKVT
PSRELIAVALAAKDRMRLLIEQPETPESAEGDAILRDLKAIVDASDLPSAGEGGDAPVAAREQPAEITWRIRFRLARDAM
AMGTNPLLLLDELRTLGSATIVALTGEVPSLEVLVPSDCHLAWDVMLTTSQPRTAIEDVFMFVIDDMELSIDLLESGEED
RRIGEILVERGDVAQEAVDTAVSRQLPLGTLLVESGNLSPDKLTSALAEQQHLRTETKVVAKGADSIRVPAERLDELMDR
VGELVIAQSRLTQVAASINDMQVKAIAEEIERLAHELRDTTMGVRMVPISSLFGRFRRLVHDLAHDLGKQIELTTFGEET
ELDKTVIERLNDPLIHLIRNSIDHGLETPEGRKEAGKPPAGRITLSARHSGAEVLVSIIDDGRGLDRARIQARAEEQGLL
APGVKLSDNDLFQVIFQAGFSTAKVVTSLSGRGVGMDVVKRTIEGLRGKIDIASTPGKGTELTLRLPLTLAIIDGLLVRV
GKARYVLPLSAVEECVELSAEEDGRSRGRSFLNIRGDLVPFLRLRELFQVSAPADPYQKVVIVSSGEFRVGLVVDQVIGN
HQTVIKSLSKLHADVETFSGATILGDGAVALILDIGHLVKLGLTYESQFMAAG

Sequences:

>Translated_693_residues
MTPMDPSETFRQEAQELLEQLEQALLDLEHAPDDGDLIDSAFRALHTIKGSGSMFGFDAVAAFTHHVETAFDLVRKGKVT
PSRELIAVALAAKDRMRLLIEQPETPESAEGDAILRDLKAIVDASDLPSAGEGGDAPVAAREQPAEITWRIRFRLARDAM
AMGTNPLLLLDELRTLGSATIVALTGEVPSLEVLVPSDCHLAWDVMLTTSQPRTAIEDVFMFVIDDMELSIDLLESGEED
RRIGEILVERGDVAQEAVDTAVSRQLPLGTLLVESGNLSPDKLTSALAEQQHLRTETKVVAKGADSIRVPAERLDELMDR
VGELVIAQSRLTQVAASINDMQVKAIAEEIERLAHELRDTTMGVRMVPISSLFGRFRRLVHDLAHDLGKQIELTTFGEET
ELDKTVIERLNDPLIHLIRNSIDHGLETPEGRKEAGKPPAGRITLSARHSGAEVLVSIIDDGRGLDRARIQARAEEQGLL
APGVKLSDNDLFQVIFQAGFSTAKVVTSLSGRGVGMDVVKRTIEGLRGKIDIASTPGKGTELTLRLPLTLAIIDGLLVRV
GKARYVLPLSAVEECVELSAEEDGRSRGRSFLNIRGDLVPFLRLRELFQVSAPADPYQKVVIVSSGEFRVGLVVDQVIGN
HQTVIKSLSKLHADVETFSGATILGDGAVALILDIGHLVKLGLTYESQFMAAG
>Mature_692_residues
TPMDPSETFRQEAQELLEQLEQALLDLEHAPDDGDLIDSAFRALHTIKGSGSMFGFDAVAAFTHHVETAFDLVRKGKVTP
SRELIAVALAAKDRMRLLIEQPETPESAEGDAILRDLKAIVDASDLPSAGEGGDAPVAAREQPAEITWRIRFRLARDAMA
MGTNPLLLLDELRTLGSATIVALTGEVPSLEVLVPSDCHLAWDVMLTTSQPRTAIEDVFMFVIDDMELSIDLLESGEEDR
RIGEILVERGDVAQEAVDTAVSRQLPLGTLLVESGNLSPDKLTSALAEQQHLRTETKVVAKGADSIRVPAERLDELMDRV
GELVIAQSRLTQVAASINDMQVKAIAEEIERLAHELRDTTMGVRMVPISSLFGRFRRLVHDLAHDLGKQIELTTFGEETE
LDKTVIERLNDPLIHLIRNSIDHGLETPEGRKEAGKPPAGRITLSARHSGAEVLVSIIDDGRGLDRARIQARAEEQGLLA
PGVKLSDNDLFQVIFQAGFSTAKVVTSLSGRGVGMDVVKRTIEGLRGKIDIASTPGKGTELTLRLPLTLAIIDGLLVRVG
KARYVLPLSAVEECVELSAEEDGRSRGRSFLNIRGDLVPFLRLRELFQVSAPADPYQKVVIVSSGEFRVGLVVDQVIGNH
QTVIKSLSKLHADVETFSGATILGDGAVALILDIGHLVKLGLTYESQFMAAG

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=689, Percent_Identity=36.8650217706821, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75288; Mature: 75157

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS51061 R3H ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPMDPSETFRQEAQELLEQLEQALLDLEHAPDDGDLIDSAFRALHTIKGSGSMFGFDAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
AAFTHHVETAFDLVRKGKVTPSRELIAVALAAKDRMRLLIEQPETPESAEGDAILRDLKA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
IVDASDLPSAGEGGDAPVAAREQPAEITWRIRFRLARDAMAMGTNPLLLLDELRTLGSAT
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHCCCCEEHHHHHHHCCCEE
IVALTGEVPSLEVLVPSDCHLAWDVMLTTSQPRTAIEDVFMFVIDDMELSIDLLESGEED
EEEEECCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHH
RRIGEILVERGDVAQEAVDTAVSRQLPLGTLLVESGNLSPDKLTSALAEQQHLRTETKVV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AKGADSIRVPAERLDELMDRVGELVIAQSRLTQVAASINDMQVKAIAEEIERLAHELRDT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMGVRMVPISSLFGRFRRLVHDLAHDLGKQIELTTFGEETELDKTVIERLNDPLIHLIRN
HCCEEEECHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHH
SIDHGLETPEGRKEAGKPPAGRITLSARHSGAEVLVSIIDDGRGLDRARIQARAEEQGLL
HHHCCCCCCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
APGVKLSDNDLFQVIFQAGFSTAKVVTSLSGRGVGMDVVKRTIEGLRGKIDIASTPGKGT
CCCCEECCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCC
ELTLRLPLTLAIIDGLLVRVGKARYVLPLSAVEECVELSAEEDGRSRGRSFLNIRGDLVP
EEEEECCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCHHHCCCEEEEECCHHHH
FLRLRELFQVSAPADPYQKVVIVSSGEFRVGLVVDQVIGNHQTVIKSLSKLHADVETFSG
HHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHCCC
ATILGDGAVALILDIGHLVKLGLTYESQFMAAG
CEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TPMDPSETFRQEAQELLEQLEQALLDLEHAPDDGDLIDSAFRALHTIKGSGSMFGFDAV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHH
AAFTHHVETAFDLVRKGKVTPSRELIAVALAAKDRMRLLIEQPETPESAEGDAILRDLKA
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
IVDASDLPSAGEGGDAPVAAREQPAEITWRIRFRLARDAMAMGTNPLLLLDELRTLGSAT
HHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHCCCCEEHHHHHHHCCCEE
IVALTGEVPSLEVLVPSDCHLAWDVMLTTSQPRTAIEDVFMFVIDDMELSIDLLESGEED
EEEEECCCCCEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHCCCHH
RRIGEILVERGDVAQEAVDTAVSRQLPLGTLLVESGNLSPDKLTSALAEQQHLRTETKVV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
AKGADSIRVPAERLDELMDRVGELVIAQSRLTQVAASINDMQVKAIAEEIERLAHELRDT
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMGVRMVPISSLFGRFRRLVHDLAHDLGKQIELTTFGEETELDKTVIERLNDPLIHLIRN
HCCEEEECHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHH
SIDHGLETPEGRKEAGKPPAGRITLSARHSGAEVLVSIIDDGRGLDRARIQARAEEQGLL
HHHCCCCCCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCC
APGVKLSDNDLFQVIFQAGFSTAKVVTSLSGRGVGMDVVKRTIEGLRGKIDIASTPGKGT
CCCCEECCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCC
ELTLRLPLTLAIIDGLLVRVGKARYVLPLSAVEECVELSAEEDGRSRGRSFLNIRGDLVP
EEEEECCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCCCHHHCCCEEEEECCHHHH
FLRLRELFQVSAPADPYQKVVIVSSGEFRVGLVVDQVIGNHQTVIKSLSKLHADVETFSG
HHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEHHHHHCCHHHHHHHHHHHHHHHHHCCC
ATILGDGAVALILDIGHLVKLGLTYESQFMAAG
CEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]