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The map label for this gene is fadN [H]

Identifier: 83592645

GI number: 83592645

Start: 1544051

End: 1546375

Strand: Reverse

Name: fadN [H]

Synonym: Rru_A1309

Alternate gene names: 83592645

Gene position: 1546375-1544051 (Counterclockwise)

Preceding gene: 83592646

Following gene: 83592644

Centisome position: 35.53

GC content: 67.23

Gene sequence:

>2325_bases
ATGAGCGAAATCGCCAAAGTCGCCGTGATCGGCGCCGGGGTCATGGGGGCAGGAATCGCCGCCCATGTGGCCAATGCCGG
GCTACCCGTGCTGTTGCTCGACATCGTCGCCAAGGACAGCGAAGACCGCAGCGCCATCGCCGCCAAGGCGATCGAGCGCC
TGCAAAAAAGCGAGCCCTCCGCCTTCATGGGCAAGGCGGCGGCCAAGCGGGTGACGCCGGGCAATATCGAAGACGATCTT
GATAAGCTGGCCGATTGCGATTGGATCGTCGAGGCCATCTTGGAGCGCGCCGATCTCAAGCAGGATCTTTACCGGCGGGT
CGAGGCCGTGCGCAAGGACGGCTCGGTGGTGTCATCCAACACCTCGACCATTCCACTCTCGACCCTGACCGAGGGCCTGG
GCGACCGCTTCGCCGAGGATTTCCTGGTCACCCACTTCTTCAACCCGCCGCGCTACATGCGCCTGCTTGAAGTGGTGGCC
GGCGCCCAGACCAAGCCCGAGGTGGTGGAGACCATCAGCCGCTTCGCCGACCATCGCCTGGGCAAGGGCGTGGTCGCCTG
TAAGGACCGCCCGGGCTTCATCGCCAACCGCTTGGGCGTTTACTGGCTGCAGGCCGCCGTCGCCGAGGCCTTTGATCATA
ATCTCTCGATCGAAGAGGCCGACGCCGTGATCGGCCGGCCGATGGGCATTCCCAAGACCGGGGTCTTCGGGCTGCTCGAT
CTGGTCGGCCTCGACCTGATGCCCCATGTCAACGCCAGCCTCGCCGCCGCCCTGCCCAAGGACGATCCCTTCCAGGCCTA
TAACCGGCCGCTGGCGGTCGTCGATAAGATGATCGCCGAAGGCTATACCGGGCGCAAAGGCAAGGGCGGCTTCTATCGCA
TCACCCGCGCCAAGGGCGGCAAGGTCAAGGAAGCCATCGACCTGCACAGCGGCGAATGGCGGCCCGAACGCCCGGCCGAT
CCCGAGGCCATCCGCGTCGCCGGCCGCGACCTGCGCGCCCTGCTCGATCACGACAGCCCCGTCGGCCGCTATGCCCGCGC
CGTGCTGACCCGTACGCTGAGCTATGCCGCCCTGCTGGTTGGCGACGCCGCCGATGATCCGGCGGCGATCGATGACGCCA
TGCGCCTGGGCTACAATTGGAAGCAGGGGCCGTTCGAGTTGATCGACCGCCTGGGCGCGGATTGGCTGGCGGCGGCGCTG
ACCGCCCAAGGCGACCCGGTTCCCCCCTATCTGGCCCAGGCCGCCGGCCGCAAGGTGTACAAGGTGACCGAGGGGCACCG
CGAGATCTTGCAGCCCGATGGCGCCTACCGCAGCCATCTGCGCCCCGACGGCGTGCTGCTGCTCGAAGACATCAAGCTGG
TGTCCAAGCCGCTGCTGAAGAACGGCTCGGCGGCGCTGTGGGACATCGGCGACGGCGTGGCCTGCTTCGAGTTCACCTCG
AAGATGAACGCGCTTGATCCCGATATCCTTGGCTTGCTCGCCAAATCGCTGAAGCTGGTGGCCCGCCAGTTCAAGGCCCT
GGTCATCTATAACGAGGGCGGCGCCTTTTCCGCCGGCGCCAACCTTGGGCTCGCCCTGTTCGCCGCCAATATCGCCGCCT
GGAGCGAGATCGAAACCCTGGTCGCCGAGGGTCAGAAGACCTATCGGGCGCTGCGCGAAGCCCCCTTCCCCGTCGTCGGC
GCCCCCTCGGGTCTGGCTTTGGGCGGCGGCTGCGAGATCCTGCTCCATTGCGACGCCGTCCAGGCCCATGCGGAAAGCTA
TATCGGTCTGGTCGAGGTCGGCGTCGGGCTGGTTCCGGCCTGGGGCGGCTGCACGGAAATGCTCCACCGCTGGTCGACCC
TCGGCCAATTGCCCAAGGGGCCGATGCCGGCGCTTTCCAAAGTGTTCGAGACCGTGAGCACGGCGACCGTCGCCAAATCG
GCGGCCGAGGCCAAGGAGCTTTTGTTCCTGCGCGAGGGCGACGGCATCACCATGAACCGCGACCGCCTGCTGGCCGACGC
CAAGGCCAAGGCCCTGGCCCTGGTCGAGGGCTACGCCCCGCCGCCCAGGCGGGAATTCACCCTGCCCGGCGCCGCCGCCA
AGACCGGCCTCGACATGGCGGTCGCCAGCGTCCAGCGCCAGGGCAAGGCCACCCCCTATGACGGCGTGGTCTGCGGCGCC
TTGGCCGATATTCTTTCGGGCGGCGATACCGACATCACCGTGACGCTGACGGAAGACGCTCTGCTCGAGCTTGAGCGCAC
GCACTTCATGGCCTTGGCCCGGCGGCCGGAAACCCTGGCCCGCATCGAGACCATGCTGCTCACCGGCAAGCCCTTGCGCA
ACTAG

Upstream 100 bases:

>100_bases
CTCAAGCGTCAGGGTGGGCGCTACGCGCTAGCCACCCAGTGCATCGGCGGTGGCCAGGGTATCGCCACCATCCTCGAAGC
GGTCTGACAGGGAGCGTGAG

Downstream 100 bases:

>100_bases
CATCCCGTCCCGATCCAAGAAGGAGAAATCCCATGGCCGGATACAAGGCTCCCCTGCGCGACATGCGCTATGTGCTTTAC
GACTTGTTCGATGGCGCGTC

Product: 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MSEIAKVAVIGAGVMGAGIAAHVANAGLPVLLLDIVAKDSEDRSAIAAKAIERLQKSEPSAFMGKAAAKRVTPGNIEDDL
DKLADCDWIVEAILERADLKQDLYRRVEAVRKDGSVVSSNTSTIPLSTLTEGLGDRFAEDFLVTHFFNPPRYMRLLEVVA
GAQTKPEVVETISRFADHRLGKGVVACKDRPGFIANRLGVYWLQAAVAEAFDHNLSIEEADAVIGRPMGIPKTGVFGLLD
LVGLDLMPHVNASLAAALPKDDPFQAYNRPLAVVDKMIAEGYTGRKGKGGFYRITRAKGGKVKEAIDLHSGEWRPERPAD
PEAIRVAGRDLRALLDHDSPVGRYARAVLTRTLSYAALLVGDAADDPAAIDDAMRLGYNWKQGPFELIDRLGADWLAAAL
TAQGDPVPPYLAQAAGRKVYKVTEGHREILQPDGAYRSHLRPDGVLLLEDIKLVSKPLLKNGSAALWDIGDGVACFEFTS
KMNALDPDILGLLAKSLKLVARQFKALVIYNEGGAFSAGANLGLALFAANIAAWSEIETLVAEGQKTYRALREAPFPVVG
APSGLALGGGCEILLHCDAVQAHAESYIGLVEVGVGLVPAWGGCTEMLHRWSTLGQLPKGPMPALSKVFETVSTATVAKS
AAEAKELLFLREGDGITMNRDRLLADAKAKALALVEGYAPPPRREFTLPGAAAKTGLDMAVASVQRQGKATPYDGVVCGA
LADILSGGDTDITVTLTEDALLELERTHFMALARRPETLARIETMLLTGKPLRN

Sequences:

>Translated_774_residues
MSEIAKVAVIGAGVMGAGIAAHVANAGLPVLLLDIVAKDSEDRSAIAAKAIERLQKSEPSAFMGKAAAKRVTPGNIEDDL
DKLADCDWIVEAILERADLKQDLYRRVEAVRKDGSVVSSNTSTIPLSTLTEGLGDRFAEDFLVTHFFNPPRYMRLLEVVA
GAQTKPEVVETISRFADHRLGKGVVACKDRPGFIANRLGVYWLQAAVAEAFDHNLSIEEADAVIGRPMGIPKTGVFGLLD
LVGLDLMPHVNASLAAALPKDDPFQAYNRPLAVVDKMIAEGYTGRKGKGGFYRITRAKGGKVKEAIDLHSGEWRPERPAD
PEAIRVAGRDLRALLDHDSPVGRYARAVLTRTLSYAALLVGDAADDPAAIDDAMRLGYNWKQGPFELIDRLGADWLAAAL
TAQGDPVPPYLAQAAGRKVYKVTEGHREILQPDGAYRSHLRPDGVLLLEDIKLVSKPLLKNGSAALWDIGDGVACFEFTS
KMNALDPDILGLLAKSLKLVARQFKALVIYNEGGAFSAGANLGLALFAANIAAWSEIETLVAEGQKTYRALREAPFPVVG
APSGLALGGGCEILLHCDAVQAHAESYIGLVEVGVGLVPAWGGCTEMLHRWSTLGQLPKGPMPALSKVFETVSTATVAKS
AAEAKELLFLREGDGITMNRDRLLADAKAKALALVEGYAPPPRREFTLPGAAAKTGLDMAVASVQRQGKATPYDGVVCGA
LADILSGGDTDITVTLTEDALLELERTHFMALARRPETLARIETMLLTGKPLRN
>Mature_773_residues
SEIAKVAVIGAGVMGAGIAAHVANAGLPVLLLDIVAKDSEDRSAIAAKAIERLQKSEPSAFMGKAAAKRVTPGNIEDDLD
KLADCDWIVEAILERADLKQDLYRRVEAVRKDGSVVSSNTSTIPLSTLTEGLGDRFAEDFLVTHFFNPPRYMRLLEVVAG
AQTKPEVVETISRFADHRLGKGVVACKDRPGFIANRLGVYWLQAAVAEAFDHNLSIEEADAVIGRPMGIPKTGVFGLLDL
VGLDLMPHVNASLAAALPKDDPFQAYNRPLAVVDKMIAEGYTGRKGKGGFYRITRAKGGKVKEAIDLHSGEWRPERPADP
EAIRVAGRDLRALLDHDSPVGRYARAVLTRTLSYAALLVGDAADDPAAIDDAMRLGYNWKQGPFELIDRLGADWLAAALT
AQGDPVPPYLAQAAGRKVYKVTEGHREILQPDGAYRSHLRPDGVLLLEDIKLVSKPLLKNGSAALWDIGDGVACFEFTSK
MNALDPDILGLLAKSLKLVARQFKALVIYNEGGAFSAGANLGLALFAANIAAWSEIETLVAEGQKTYRALREAPFPVVGA
PSGLALGGGCEILLHCDAVQAHAESYIGLVEVGVGLVPAWGGCTEMLHRWSTLGQLPKGPMPALSKVFETVSTATVAKSA
AEAKELLFLREGDGITMNRDRLLADAKAKALALVEGYAPPPRREFTLPGAAAKTGLDMAVASVQRQGKATPYDGVVCGAL
ADILSGGDTDITVTLTEDALLELERTHFMALARRPETLARIETMLLTGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=303, Percent_Identity=32.6732673267327, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI296179427, Length=320, Percent_Identity=30.9375, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI20127408, Length=292, Percent_Identity=27.3972602739726, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI261878539, Length=403, Percent_Identity=25.5583126550869, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI68989263, Length=396, Percent_Identity=25.7575757575758, Blast_Score=87, Evalue=6e-17,
Organism=Escherichia coli, GI1787661, Length=342, Percent_Identity=30.7017543859649, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790281, Length=281, Percent_Identity=28.4697508896797, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788682, Length=229, Percent_Identity=28.82096069869, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17553560, Length=307, Percent_Identity=37.785016286645, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17549919, Length=302, Percent_Identity=33.112582781457, Blast_Score=138, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17563036, Length=295, Percent_Identity=31.864406779661, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17558304, Length=405, Percent_Identity=26.4197530864197, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17508951, Length=404, Percent_Identity=25.990099009901, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=404, Percent_Identity=25.990099009901, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71985923, Length=301, Percent_Identity=29.2358803986711, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25144276, Length=330, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71985930, Length=298, Percent_Identity=26.510067114094, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24583077, Length=441, Percent_Identity=26.3038548752834, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24583079, Length=441, Percent_Identity=26.3038548752834, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19921000, Length=442, Percent_Identity=26.4705882352941, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI45549573, Length=243, Percent_Identity=29.2181069958848, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI20129993, Length=298, Percent_Identity=27.8523489932886, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 82728; Mature: 82597

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIAKVAVIGAGVMGAGIAAHVANAGLPVLLLDIVAKDSEDRSAIAAKAIERLQKSEPS
CCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
AFMGKAAAKRVTPGNIEDDLDKLADCDWIVEAILERADLKQDLYRRVEAVRKDGSVVSSN
HHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
TSTIPLSTLTEGLGDRFAEDFLVTHFFNPPRYMRLLEVVAGAQTKPEVVETISRFADHRL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
GKGVVACKDRPGFIANRLGVYWLQAAVAEAFDHNLSIEEADAVIGRPMGIPKTGVFGLLD
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHH
LVGLDLMPHVNASLAAALPKDDPFQAYNRPLAVVDKMIAEGYTGRKGKGGFYRITRAKGG
HHHHHHCCCCCCHHHHCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
KVKEAIDLHSGEWRPERPADPEAIRVAGRDLRALLDHDSPVGRYARAVLTRTLSYAALLV
CHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
GDAADDPAAIDDAMRLGYNWKQGPFELIDRLGADWLAAALTAQGDPVPPYLAQAAGRKVY
CCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHCCCEEE
KVTEGHREILQPDGAYRSHLRPDGVLLLEDIKLVSKPLLKNGSAALWDIGDGVACFEFTS
EEHHHHHHHHCCCCCHHHCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHH
KMNALDPDILGLLAKSLKLVARQFKALVIYNEGGAFSAGANLGLALFAANIAAWSEIETL
HCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VAEGQKTYRALREAPFPVVGAPSGLALGGGCEILLHCDAVQAHAESYIGLVEVGVGLVPA
HHCCHHHHHHHHHCCCCEEECCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCC
WGGCTEMLHRWSTLGQLPKGPMPALSKVFETVSTATVAKSAAEAKELLFLREGDGITMNR
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEECH
DRLLADAKAKALALVEGYAPPPRREFTLPGAAAKTGLDMAVASVQRQGKATPYDGVVCGA
HHHHHHHHHHHHHHEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LADILSGGDTDITVTLTEDALLELERTHFMALARRPETLARIETMLLTGKPLRN
HHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEIAKVAVIGAGVMGAGIAAHVANAGLPVLLLDIVAKDSEDRSAIAAKAIERLQKSEPS
CCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
AFMGKAAAKRVTPGNIEDDLDKLADCDWIVEAILERADLKQDLYRRVEAVRKDGSVVSSN
HHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECC
TSTIPLSTLTEGLGDRFAEDFLVTHFFNPPRYMRLLEVVAGAQTKPEVVETISRFADHRL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHC
GKGVVACKDRPGFIANRLGVYWLQAAVAEAFDHNLSIEEADAVIGRPMGIPKTGVFGLLD
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHH
LVGLDLMPHVNASLAAALPKDDPFQAYNRPLAVVDKMIAEGYTGRKGKGGFYRITRAKGG
HHHHHHCCCCCCHHHHCCCCCCCHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
KVKEAIDLHSGEWRPERPADPEAIRVAGRDLRALLDHDSPVGRYARAVLTRTLSYAALLV
CHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHC
GDAADDPAAIDDAMRLGYNWKQGPFELIDRLGADWLAAALTAQGDPVPPYLAQAAGRKVY
CCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHCCCEEE
KVTEGHREILQPDGAYRSHLRPDGVLLLEDIKLVSKPLLKNGSAALWDIGDGVACFEFTS
EEHHHHHHHHCCCCCHHHCCCCCCEEEHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHH
KMNALDPDILGLLAKSLKLVARQFKALVIYNEGGAFSAGANLGLALFAANIAAWSEIETL
HCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VAEGQKTYRALREAPFPVVGAPSGLALGGGCEILLHCDAVQAHAESYIGLVEVGVGLVPA
HHCCHHHHHHHHHCCCCEEECCCCCEECCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCC
WGGCTEMLHRWSTLGQLPKGPMPALSKVFETVSTATVAKSAAEAKELLFLREGDGITMNR
CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEECH
DRLLADAKAKALALVEGYAPPPRREFTLPGAAAKTGLDMAVASVQRQGKATPYDGVVCGA
HHHHHHHHHHHHHHEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LADILSGGDTDITVTLTEDALLELERTHFMALARRPETLARIETMLLTGKPLRN
HHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]