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The map label for this gene is dmsA [H]

Identifier: 83592623

GI number: 83592623

Start: 1518208

End: 1520679

Strand: Direct

Name: dmsA [H]

Synonym: Rru_A1287

Alternate gene names: 83592623

Gene position: 1518208-1520679 (Clockwise)

Preceding gene: 83592622

Following gene: 83592624

Centisome position: 34.88

GC content: 64.32

Gene sequence:

>2472_bases
ATGTCCAAGATGTCTCCCCCGACCGCCTTCGCCGCACAAACCCGGCGCACCTTCCTGAAAGCGAGCGCCGCCGCCGGTGC
CCTTGGATTGGTCGCCCCCTCGCTGTTGTCTGCGGGCGTGGCGCGGGCGGCCGAGGATGGCGAGGTCCTGACCGGGTCGC
ATTGGGGCGCCTTCCGCGCCACCGTGAAGGGCGGCAAGATGACCGCCATCAAGCCCTGGGAAAAGGATCCCCATCCCAGC
CATCAGCTGACCGGCGTGATGGATTCGATCTATTCGCCCACCCGCATCAAATACCCGATGGTCCGCCGCGCCTTCCTTGA
AAAGGGTCCGGGCGCCTCGCCGGAAACCCGCGGCGCCGGCGATTTCGTGCGCGTGACCTGGGATCAGGCGCTTGATCTGG
TGGCCAAGGAACTGACCCGGGTGCGCAAGGACCATGGGCCGACCTCGATCTTCGCCGGATCCTATGGCTGGATGAGCCCG
GGCAAGCTGCATAACTGCCGCAGTCTGGTGCGCCGCCTTCTCAATCAGACCGGCGGCTTCGTCAGCAGCTCGGGCGATTA
TTCGACTGGCGCGTCCCAGGTGATCATGCCCCATGTCATGGGCACGCTTGAGGTCTATGAGCAGCCGACCGTTTGGCCGG
TGGTGGTCGAGCATTCCGATCTGGTCGTCTTCTGGGGCGCCGATCCGATGACCACCAACCAGATCGGTTGGCTGATCCCC
GATCACGGCGCCTATGTCGGCCTCAAGGCCCTCAAGGAGTCCGGCAAGAAGGTGATCTGCATCGATCCGGTGCGCACCGA
AACCTGCGACTATCTGGGCGCCGAATGGATCGCCCCCAAGCCGCAGACCGATATGGCGATGATGCTGGGCGTCGCCCACA
CGCTTTATACCGAGAAGCTCCACGATCAGAGCTTCCTTGATGATTACACCTTCGGCTTCGATCGCTTCTTGCCCTATCTG
ACTGGCGAAAGCGACAAGACGCCCAAGAGCGCCGAATGGGCTTCGGCGATCTGCGGCATTCCGGCCGAGGTGATCAAGGA
TCTCGCCCGCCGTATCGTCAAGGGCCGCACCATGCTGGCCTCGGGCTGGTCGATGCAGCGCCAGCACCATGGCGAGCAGA
TTCACTGGATGTTGGTGACTCTCGCCTCGATGGTCGGTCAGATCGGCCTGCCGGGCGGCGGCTTTGGCCTTAGCTACCAT
TACGCCAACGGCGGCTCGCCCAGCGCCACCGGTCCCGTGCTGCCCGCCATCAGCGACGGCAGCGCCGCGGTGAAGGGGGC
GGCTTGGCTGGCCGCCGGCGGTGCGGCCAGCATTCCCGTCGCCCGCGTCGTCGACATGCTGATGAATCCGGGCAAGGAGT
TCGATTTCAACGGCACCAAGGCGATTTATCCCGATACCAAGCTGATCTACTGGACCGGCGGCAATCCCTTCGCCCACCAC
CAGAACCGTAACCGCATGGTCGAGGCCTTCCGCAAGGTCGAGACCTTCATCGTCCATGACTTCCAGTGGACGGCGACGGC
CCGCCACGCCGATATCGTGCTGCCCGCCACCACCAGCTACGAGCGCAATGATATCGAGCAGATCGGCGATTATGCGCTCA
GCTCGGTTCTGGCGATGAAGAAGGTGGTCGAGCCGGTGTTCGAGGCCCGCTCCGATTTCGATATCCTGGCCGCGGTGGCC
GAGCGCCTGGGCACGCGCGACGCCTTCACCGAAGGCAAGGACGAAATGGGCTGGATCAAGGAGTTCTATGACAACGCCCT
GGGTCAGGCCAAGGCCAAGGGTGTGACGATGCCCGACTTCGAGACCTTCTGGAAGGGCGAGGGCGTGGTCAGCTTCCCGA
TCTCCGATGAAGCCAAGGCCTTCGTCCGTTACAGCGCCTTCCGCGAGGACCCGCTGCTCGAGCCGCTGGGCACTCCGACC
GGCAAGATCGAGATCTATTCCAAGAACATCGAAAAGATGGGCTATGACGATTGCCCGGCCCATCCGACCTGGATGGAACC
GGTCGAGCGCCTGGACGGCCCGGGGGCGAAGTTCCCGCTGCATATCACGACCAGCCACCCGAAAAGCCGTCTGCATTCCC
AGCTCTGCGGTACCAAGCTGCGCGACAGCTACACGGTGGCCGGGCGCGAACCCTGCCTGATCAACGAGGCCGATGCCAAG
GCGCGCGGCATCAGCAATGGCGATGTGGTGCGGGTGTTCAATGATCGCGGCCAGATCCTGGCCGGGGCCGTCGTCACCAA
TGCCATCCGCCCGGGCGTGATCCGGGTCAACGAGGGCGGTTGGTACGACCCGACCGAGCCGACCAAGCCGGGCAGCCTGT
GCAAATACGGCGACGTCAACGTGCTGACCGTTGATATCGGCACCTCCAAACTGGCCCAGGGCAACTGCGGCCATACCGCG
ATCGGCGATGTCGAGAAATACGCCGAGGCCGCGCCCGCCGTCACCGTCTTCGCCGCGCCGAAGAACGCCTGA

Upstream 100 bases:

>100_bases
CGCTTTGTCTGGGCGGTCGCGGGGTCCGGTTCCCGCTTCTGGGGGCCGTCGCACGCGGCTTTCAGGGACTTCCCGAGATG
AACAACAAGGATCGCAACCC

Downstream 100 bases:

>100_bases
CGCCTGAGCGCTCCATGCTTCGGGACCGCCGCTTGCCTCCCGGCGGTCCCGGAGCCCTTCTCTCCGGCCTTCCCCCCTTT
TCCGGAGTCTGCGATGCGCG

Product: trimethylamine-N-oxide reductase (cytochrome c)

Products: NAD+; trimethylamine; H2O

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 823; Mature: 822

Protein sequence:

>823_residues
MSKMSPPTAFAAQTRRTFLKASAAAGALGLVAPSLLSAGVARAAEDGEVLTGSHWGAFRATVKGGKMTAIKPWEKDPHPS
HQLTGVMDSIYSPTRIKYPMVRRAFLEKGPGASPETRGAGDFVRVTWDQALDLVAKELTRVRKDHGPTSIFAGSYGWMSP
GKLHNCRSLVRRLLNQTGGFVSSSGDYSTGASQVIMPHVMGTLEVYEQPTVWPVVVEHSDLVVFWGADPMTTNQIGWLIP
DHGAYVGLKALKESGKKVICIDPVRTETCDYLGAEWIAPKPQTDMAMMLGVAHTLYTEKLHDQSFLDDYTFGFDRFLPYL
TGESDKTPKSAEWASAICGIPAEVIKDLARRIVKGRTMLASGWSMQRQHHGEQIHWMLVTLASMVGQIGLPGGGFGLSYH
YANGGSPSATGPVLPAISDGSAAVKGAAWLAAGGAASIPVARVVDMLMNPGKEFDFNGTKAIYPDTKLIYWTGGNPFAHH
QNRNRMVEAFRKVETFIVHDFQWTATARHADIVLPATTSYERNDIEQIGDYALSSVLAMKKVVEPVFEARSDFDILAAVA
ERLGTRDAFTEGKDEMGWIKEFYDNALGQAKAKGVTMPDFETFWKGEGVVSFPISDEAKAFVRYSAFREDPLLEPLGTPT
GKIEIYSKNIEKMGYDDCPAHPTWMEPVERLDGPGAKFPLHITTSHPKSRLHSQLCGTKLRDSYTVAGREPCLINEADAK
ARGISNGDVVRVFNDRGQILAGAVVTNAIRPGVIRVNEGGWYDPTEPTKPGSLCKYGDVNVLTVDIGTSKLAQGNCGHTA
IGDVEKYAEAAPAVTVFAAPKNA

Sequences:

>Translated_823_residues
MSKMSPPTAFAAQTRRTFLKASAAAGALGLVAPSLLSAGVARAAEDGEVLTGSHWGAFRATVKGGKMTAIKPWEKDPHPS
HQLTGVMDSIYSPTRIKYPMVRRAFLEKGPGASPETRGAGDFVRVTWDQALDLVAKELTRVRKDHGPTSIFAGSYGWMSP
GKLHNCRSLVRRLLNQTGGFVSSSGDYSTGASQVIMPHVMGTLEVYEQPTVWPVVVEHSDLVVFWGADPMTTNQIGWLIP
DHGAYVGLKALKESGKKVICIDPVRTETCDYLGAEWIAPKPQTDMAMMLGVAHTLYTEKLHDQSFLDDYTFGFDRFLPYL
TGESDKTPKSAEWASAICGIPAEVIKDLARRIVKGRTMLASGWSMQRQHHGEQIHWMLVTLASMVGQIGLPGGGFGLSYH
YANGGSPSATGPVLPAISDGSAAVKGAAWLAAGGAASIPVARVVDMLMNPGKEFDFNGTKAIYPDTKLIYWTGGNPFAHH
QNRNRMVEAFRKVETFIVHDFQWTATARHADIVLPATTSYERNDIEQIGDYALSSVLAMKKVVEPVFEARSDFDILAAVA
ERLGTRDAFTEGKDEMGWIKEFYDNALGQAKAKGVTMPDFETFWKGEGVVSFPISDEAKAFVRYSAFREDPLLEPLGTPT
GKIEIYSKNIEKMGYDDCPAHPTWMEPVERLDGPGAKFPLHITTSHPKSRLHSQLCGTKLRDSYTVAGREPCLINEADAK
ARGISNGDVVRVFNDRGQILAGAVVTNAIRPGVIRVNEGGWYDPTEPTKPGSLCKYGDVNVLTVDIGTSKLAQGNCGHTA
IGDVEKYAEAAPAVTVFAAPKNA
>Mature_822_residues
SKMSPPTAFAAQTRRTFLKASAAAGALGLVAPSLLSAGVARAAEDGEVLTGSHWGAFRATVKGGKMTAIKPWEKDPHPSH
QLTGVMDSIYSPTRIKYPMVRRAFLEKGPGASPETRGAGDFVRVTWDQALDLVAKELTRVRKDHGPTSIFAGSYGWMSPG
KLHNCRSLVRRLLNQTGGFVSSSGDYSTGASQVIMPHVMGTLEVYEQPTVWPVVVEHSDLVVFWGADPMTTNQIGWLIPD
HGAYVGLKALKESGKKVICIDPVRTETCDYLGAEWIAPKPQTDMAMMLGVAHTLYTEKLHDQSFLDDYTFGFDRFLPYLT
GESDKTPKSAEWASAICGIPAEVIKDLARRIVKGRTMLASGWSMQRQHHGEQIHWMLVTLASMVGQIGLPGGGFGLSYHY
ANGGSPSATGPVLPAISDGSAAVKGAAWLAAGGAASIPVARVVDMLMNPGKEFDFNGTKAIYPDTKLIYWTGGNPFAHHQ
NRNRMVEAFRKVETFIVHDFQWTATARHADIVLPATTSYERNDIEQIGDYALSSVLAMKKVVEPVFEARSDFDILAAVAE
RLGTRDAFTEGKDEMGWIKEFYDNALGQAKAKGVTMPDFETFWKGEGVVSFPISDEAKAFVRYSAFREDPLLEPLGTPTG
KIEIYSKNIEKMGYDDCPAHPTWMEPVERLDGPGAKFPLHITTSHPKSRLHSQLCGTKLRDSYTVAGREPCLINEADAKA
RGISNGDVVRVFNDRGQILAGAVVTNAIRPGVIRVNEGGWYDPTEPTKPGSLCKYGDVNVLTVDIGTSKLAQGNCGHTAI
GDVEKYAEAAPAVTVFAAPKNA

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=814, Percent_Identity=49.2628992628993, Blast_Score=795, Evalue=0.0,
Organism=Escherichia coli, GI1787231, Length=828, Percent_Identity=49.1545893719807, Blast_Score=795, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=792, Percent_Identity=45.959595959596, Blast_Score=724, Evalue=0.0,
Organism=Escherichia coli, GI87081797, Length=878, Percent_Identity=30.8656036446469, Blast_Score=321, Evalue=1e-88,
Organism=Escherichia coli, GI1787870, Length=861, Percent_Identity=30.8943089430894, Blast_Score=299, Evalue=4e-82,
Organism=Escherichia coli, GI171474008, Length=857, Percent_Identity=29.8716452742124, Blast_Score=276, Evalue=4e-75,
Organism=Escherichia coli, GI3868721, Length=690, Percent_Identity=22.8985507246377, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.6.6.9

Molecular weight: Translated: 89342; Mature: 89210

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKMSPPTAFAAQTRRTFLKASAAAGALGLVAPSLLSAGVARAAEDGEVLTGSHWGAFRA
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEE
TVKGGKMTAIKPWEKDPHPSHQLTGVMDSIYSPTRIKYPMVRRAFLEKGPGASPETRGAG
EECCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DFVRVTWDQALDLVAKELTRVRKDHGPTSIFAGSYGWMSPGKLHNCRSLVRRLLNQTGGF
CEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
VSSSGDYSTGASQVIMPHVMGTLEVYEQPTVWPVVVEHSDLVVFWGADPMTTNQIGWLIP
EECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCCCCCCEEEC
DHGAYVGLKALKESGKKVICIDPVRTETCDYLGAEWIAPKPQTDMAMMLGVAHTLYTEKL
CCCCHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HDQSFLDDYTFGFDRFLPYLTGESDKTPKSAEWASAICGIPAEVIKDLARRIVKGRTMLA
HHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEE
SGWSMQRQHHGEQIHWMLVTLASMVGQIGLPGGGFGLSYHYANGGSPSATGPVLPAISDG
CCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCEECCC
SAAVKGAAWLAAGGAASIPVARVVDMLMNPGKEFDFNGTKAIYPDTKLIYWTGGNPFAHH
CCHHCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEECCCCCCCC
QNRNRMVEAFRKVETFIVHDFQWTATARHADIVLPATTSYERNDIEQIGDYALSSVLAMK
CCHHHHHHHHHHHHHHHEECEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
KVVEPVFEARSDFDILAAVAERLGTRDAFTEGKDEMGWIKEFYDNALGQAKAKGVTMPDF
HHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
ETFWKGEGVVSFPISDEAKAFVRYSAFREDPLLEPLGTPTGKIEIYSKNIEKMGYDDCPA
HHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHCCCCCCCC
HPTWMEPVERLDGPGAKFPLHITTSHPKSRLHSQLCGTKLRDSYTVAGREPCLINEADAK
CCCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCHHCCCEEECCCCCCEEECCCHH
ARGISNGDVVRVFNDRGQILAGAVVTNAIRPGVIRVNEGGWYDPTEPTKPGSLCKYGDVN
HCCCCCCCEEEEECCCCCEEEHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCE
VLTVDIGTSKLAQGNCGHTAIGDVEKYAEAAPAVTVFAAPKNA
EEEEECCCCHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure 
SKMSPPTAFAAQTRRTFLKASAAAGALGLVAPSLLSAGVARAAEDGEVLTGSHWGAFRA
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEE
TVKGGKMTAIKPWEKDPHPSHQLTGVMDSIYSPTRIKYPMVRRAFLEKGPGASPETRGAG
EECCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
DFVRVTWDQALDLVAKELTRVRKDHGPTSIFAGSYGWMSPGKLHNCRSLVRRLLNQTGGF
CEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
VSSSGDYSTGASQVIMPHVMGTLEVYEQPTVWPVVVEHSDLVVFWGADPMTTNQIGWLIP
EECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCCCCCCEEEC
DHGAYVGLKALKESGKKVICIDPVRTETCDYLGAEWIAPKPQTDMAMMLGVAHTLYTEKL
CCCCHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HDQSFLDDYTFGFDRFLPYLTGESDKTPKSAEWASAICGIPAEVIKDLARRIVKGRTMLA
HHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEEE
SGWSMQRQHHGEQIHWMLVTLASMVGQIGLPGGGFGLSYHYANGGSPSATGPVLPAISDG
CCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCEECCC
SAAVKGAAWLAAGGAASIPVARVVDMLMNPGKEFDFNGTKAIYPDTKLIYWTGGNPFAHH
CCHHCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEECCCCCCCC
QNRNRMVEAFRKVETFIVHDFQWTATARHADIVLPATTSYERNDIEQIGDYALSSVLAMK
CCHHHHHHHHHHHHHHHEECEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
KVVEPVFEARSDFDILAAVAERLGTRDAFTEGKDEMGWIKEFYDNALGQAKAKGVTMPDF
HHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
ETFWKGEGVVSFPISDEAKAFVRYSAFREDPLLEPLGTPTGKIEIYSKNIEKMGYDDCPA
HHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHHHCCCCCCCC
HPTWMEPVERLDGPGAKFPLHITTSHPKSRLHSQLCGTKLRDSYTVAGREPCLINEADAK
CCCHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCHHCCCEEECCCCCCEEECCCHH
ARGISNGDVVRVFNDRGQILAGAVVTNAIRPGVIRVNEGGWYDPTEPTKPGSLCKYGDVN
HCCCCCCCEEEEECCCCCEEEHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCE
VLTVDIGTSKLAQGNCGHTAIGDVEKYAEAAPAVTVFAAPKNA
EEEEECCCCHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; trimethylamine N-oxide

Specific reaction: NADH + H+ + trimethylamine N-oxide = NAD+ + trimethylamine + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]