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The map label for this gene is yieH [C]

Identifier: 83592604

GI number: 83592604

Start: 1489540

End: 1490187

Strand: Direct

Name: yieH [C]

Synonym: Rru_A1268

Alternate gene names: 83592604

Gene position: 1489540-1490187 (Clockwise)

Preceding gene: 83592603

Following gene: 83592605

Centisome position: 34.22

GC content: 68.36

Gene sequence:

>648_bases
ATGACGCCTCCCAAGGCCATCGCCTGGGATATCGACGGAACCCTGATCGATAGCGAACCCACCCACCTGCGTGCCCTGAT
AACCGTTTCCGCCGCCCATGGGGTCGATCTGACCTCGGGCCCCGAGGATCGCTTCCTGGGCGTGCATATGGCCGATGTCT
GGACGCTTTTGCGCCCCCGCTATACCGGGGGGCTGACTTACGAGCGGTGGCTGGCCGAGATCATCGCCTGTTATGGTGAC
GACCGCGCCACCTTGGCGCCGATGCCGGGCGCGCTCGATACCGTGGCCGCCTTCGCCGCCGCCGGCATTCCCCAGGCCTG
CGTGTCGAATTCCCTGCGCGAGATCGTCGACGCCAATCTGGCCGTTCTCGGCATCGCCCCGCAGCTCGCCTTTTCGCTGT
CGTTTGAGGACGTGCCGGCGGGCAAGCCCGATCCCGCCCCCTATCGGCTGGCCGCCCGGCGTTTCGGCGTCGATCCCGCT
AGCGTCTGGGCGATCGAAGACAGCCTGACCGGCGCCCGCTCGGCCCTGGATGCCGGGCTGACCCTGTTCCTGCTCGGCGA
CCACCCCGGCCGCCCCATCCCCCCGGGCGCCATCCGCATCTCCTCGGTCAGCGAGGTGCTGACGGCCTTTCAGAAGCTGG
CGGCTTAA

Upstream 100 bases:

>100_bases
TAACACCCGATCCGGCCAAGGCCGAGGTTTATGATCGCCTGTACCGGGACTTCTCGGCCCTTTATGCCACTCTTCATCCC
TTCTTTCATCGGAGTAGACC

Downstream 100 bases:

>100_bases
AGGAAAGGCTCGGTGAGCAAGCCGTTGTCCCTAAGGGAGCGCAAGGGTAGAATTCCATAGCTCTTGGTAGAATGGTGGCG
ATGATGAGCCTTACCATCAA

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MTPPKAIAWDIDGTLIDSEPTHLRALITVSAAHGVDLTSGPEDRFLGVHMADVWTLLRPRYTGGLTYERWLAEIIACYGD
DRATLAPMPGALDTVAAFAAAGIPQACVSNSLREIVDANLAVLGIAPQLAFSLSFEDVPAGKPDPAPYRLAARRFGVDPA
SVWAIEDSLTGARSALDAGLTLFLLGDHPGRPIPPGAIRISSVSEVLTAFQKLAA

Sequences:

>Translated_215_residues
MTPPKAIAWDIDGTLIDSEPTHLRALITVSAAHGVDLTSGPEDRFLGVHMADVWTLLRPRYTGGLTYERWLAEIIACYGD
DRATLAPMPGALDTVAAFAAAGIPQACVSNSLREIVDANLAVLGIAPQLAFSLSFEDVPAGKPDPAPYRLAARRFGVDPA
SVWAIEDSLTGARSALDAGLTLFLLGDHPGRPIPPGAIRISSVSEVLTAFQKLAA
>Mature_214_residues
TPPKAIAWDIDGTLIDSEPTHLRALITVSAAHGVDLTSGPEDRFLGVHMADVWTLLRPRYTGGLTYERWLAEIIACYGDD
RATLAPMPGALDTVAAFAAAGIPQACVSNSLREIVDANLAVLGIAPQLAFSLSFEDVPAGKPDPAPYRLAARRFGVDPAS
VWAIEDSLTGARSALDAGLTLFLLGDHPGRPIPPGAIRISSVSEVLTAFQKLAA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=203, Percent_Identity=29.064039408867, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1788021, Length=181, Percent_Identity=31.4917127071823, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR000150
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 22666; Mature: 22535

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPKAIAWDIDGTLIDSEPTHLRALITVSAAHGVDLTSGPEDRFLGVHMADVWTLLRPR
CCCCCCEEEECCCEEECCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHCCC
YTGGLTYERWLAEIIACYGDDRATLAPMPGALDTVAAFAAAGIPQACVSNSLREIVDANL
CCCCCCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCE
AVLGIAPQLAFSLSFEDVPAGKPDPAPYRLAARRFGVDPASVWAIEDSLTGARSALDAGL
EEEEECHHHEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHCCE
TLFLLGDHPGRPIPPGAIRISSVSEVLTAFQKLAA
EEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPPKAIAWDIDGTLIDSEPTHLRALITVSAAHGVDLTSGPEDRFLGVHMADVWTLLRPR
CCCCCEEEECCCEEECCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEHHHHHHHHHCCC
YTGGLTYERWLAEIIACYGDDRATLAPMPGALDTVAAFAAAGIPQACVSNSLREIVDANL
CCCCCCHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCE
AVLGIAPQLAFSLSFEDVPAGKPDPAPYRLAARRFGVDPASVWAIEDSLTGARSALDAGL
EEEEECHHHEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHEEEEHHHHHHHHHHHHCCE
TLFLLGDHPGRPIPPGAIRISSVSEVLTAFQKLAA
EEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA