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The map label for this gene is obgE

Identifier: 83592576

GI number: 83592576

Start: 1463132

End: 1464307

Strand: Reverse

Name: obgE

Synonym: Rru_A1240

Alternate gene names: 83592576

Gene position: 1464307-1463132 (Counterclockwise)

Preceding gene: 83592577

Following gene: 83592575

Centisome position: 33.64

GC content: 67.01

Gene sequence:

>1176_bases
ATGAAGTTCCTCGACCAAGCCAAGATCTTCGTCAAAAGCGGTGATGGCGGGAACGGCTGCGTCGCCTTCCGTCGGGAAAA
GAACATCGAGTTCGGCGGGCCCGATGGCGGCCATGGCGGACGGGGCGCCGACGTGATCGTCGAAGCCGTGCCCAATCTCA
ACACCCTGATCGATTTTCGCTATCAGCAGCATTTCAAGGCGGCGCGCGGTCGCGACGGCTCGGGCGACAACCGCACCGGC
AAGTCGGGCGAGGCCACGATCATCAAGGTCCCCGTCGGCACCCAGATCTTCGAAGACGACCGCAAGACGCTGATCGCCGA
TCTGTCGCGCCCGGGTCAGCGGGTGCGTCTGGCCAAGGGCGGTGACGGCGGCTTTGGCAACGCCCATTACAAAAGCTCGA
CCAATCAGGCGCCGCGCCGCGCCGATCCCGGCTGGCCGGGCCAGGAGATCTGGGTGTGGCTGCGCCTGAAGCTGATCGCC
GACGCCGGGTTGATCGGCTTGCCCAACGCCGGCAAATCGACCCTGCTGGCCGCCGTCACCCGCGCCCGGCCCAAGATCGC
CGATTACCCCTTCACCACGCTGCACCCCAATCTTGGCGTCGTCCACCAGGACGCCCGCGAGTTCATCATCGCCGATATTC
CCGGGCTGATCGAAGGCGCCCATGAAGGCGCCGGTCTCGGCACCCGCTTTCTGGGCCATGTCGAGCGCTGCGCCGTGCTG
CTCCATATGATCGACGCCACCCAGGATGACGTGGCCGGGGCGTGGCGCACCGTGCGCGCCGAACTGAAGGGGCATGGCCA
GGGGCTGGACGAGAAGTCCGAGATCGTCGGCCTGTCGAAGATCGACGCCTTGCCGCCCGAGGACATCGCCGCCAAGATCG
CCGAACTCTCCGAGGCCTGCGGCGCCCCGGTGATGGCCTTCTCGGCGATTTCGGGCAAGGGACTGGCCGATGTGCTGCGC
GTGATGGCGACCCATGTCGACGAGGCCCGGGCGCTGCGCCATGCGCGCGGCGAGGCCGAGGGCGACGCCTCCGACGAGGC
GATGCGCGATGTCACCGGCATCGACCACGGCTATAACCGCCCCAGCGCGGTCGTCGATTGGGAAGACGCACCCTTCGATG
ACGATGACGACGACGATGGGGACGAGAGCGGAGACAAGGGACAGTGGACACGCTGA

Upstream 100 bases:

>100_bases
GTCCATTCCCCCTTTTTGCTGTCCCGGCTCCCCGTGATCGGATTTACGGGCGCCTGCGCTATACTCTCTTTCTTCCTTTT
CCCAAGACCGGGCGGCTGCC

Downstream 100 bases:

>100_bases
ACGCAACCGCCGCCGTCGATGCCGAGGCCATTCTCGGCAACGCCCGGCGGCTGGTGATCAAGATCGGCTCGGCCCTTCTC
GTCGATCAGGGCAGCGGGCT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKFLDQAKIFVKSGDGGNGCVAFRREKNIEFGGPDGGHGGRGADVIVEAVPNLNTLIDFRYQQHFKAARGRDGSGDNRTG
KSGEATIIKVPVGTQIFEDDRKTLIADLSRPGQRVRLAKGGDGGFGNAHYKSSTNQAPRRADPGWPGQEIWVWLRLKLIA
DAGLIGLPNAGKSTLLAAVTRARPKIADYPFTTLHPNLGVVHQDAREFIIADIPGLIEGAHEGAGLGTRFLGHVERCAVL
LHMIDATQDDVAGAWRTVRAELKGHGQGLDEKSEIVGLSKIDALPPEDIAAKIAELSEACGAPVMAFSAISGKGLADVLR
VMATHVDEARALRHARGEAEGDASDEAMRDVTGIDHGYNRPSAVVDWEDAPFDDDDDDDGDESGDKGQWTR

Sequences:

>Translated_391_residues
MKFLDQAKIFVKSGDGGNGCVAFRREKNIEFGGPDGGHGGRGADVIVEAVPNLNTLIDFRYQQHFKAARGRDGSGDNRTG
KSGEATIIKVPVGTQIFEDDRKTLIADLSRPGQRVRLAKGGDGGFGNAHYKSSTNQAPRRADPGWPGQEIWVWLRLKLIA
DAGLIGLPNAGKSTLLAAVTRARPKIADYPFTTLHPNLGVVHQDAREFIIADIPGLIEGAHEGAGLGTRFLGHVERCAVL
LHMIDATQDDVAGAWRTVRAELKGHGQGLDEKSEIVGLSKIDALPPEDIAAKIAELSEACGAPVMAFSAISGKGLADVLR
VMATHVDEARALRHARGEAEGDASDEAMRDVTGIDHGYNRPSAVVDWEDAPFDDDDDDDGDESGDKGQWTR
>Mature_391_residues
MKFLDQAKIFVKSGDGGNGCVAFRREKNIEFGGPDGGHGGRGADVIVEAVPNLNTLIDFRYQQHFKAARGRDGSGDNRTG
KSGEATIIKVPVGTQIFEDDRKTLIADLSRPGQRVRLAKGGDGGFGNAHYKSSTNQAPRRADPGWPGQEIWVWLRLKLIA
DAGLIGLPNAGKSTLLAAVTRARPKIADYPFTTLHPNLGVVHQDAREFIIADIPGLIEGAHEGAGLGTRFLGHVERCAVL
LHMIDATQDDVAGAWRTVRAELKGHGQGLDEKSEIVGLSKIDALPPEDIAAKIAELSEACGAPVMAFSAISGKGLADVLR
VMATHVDEARALRHARGEAEGDASDEAMRDVTGIDHGYNRPSAVVDWEDAPFDDDDDDDGDESGDKGQWTR

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=41.1214953271028, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI111955139, Length=357, Percent_Identity=31.9327731092437, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI111955063, Length=262, Percent_Identity=30.9160305343511, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI58761500, Length=105, Percent_Identity=36.1904761904762, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4758796, Length=123, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4557537, Length=112, Percent_Identity=34.8214285714286, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789574, Length=335, Percent_Identity=49.5522388059701, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI1787454, Length=108, Percent_Identity=37.037037037037, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=332, Percent_Identity=37.6506024096386, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17552324, Length=370, Percent_Identity=29.4594594594595, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=113, Percent_Identity=38.0530973451327, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=121, Percent_Identity=30.5785123966942, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71981008, Length=91, Percent_Identity=36.2637362637363, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=38.1443298969072, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6321612, Length=113, Percent_Identity=35.3982300884956, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319281, Length=134, Percent_Identity=29.1044776119403, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129375, Length=321, Percent_Identity=37.6947040498442, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24585318, Length=305, Percent_Identity=35.0819672131148, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI21356473, Length=92, Percent_Identity=38.0434782608696, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640873, Length=104, Percent_Identity=33.6538461538462, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640877, Length=104, Percent_Identity=33.6538461538462, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640875, Length=104, Percent_Identity=33.6538461538462, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17981711, Length=113, Percent_Identity=31.858407079646, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_RHORT (Q2RV04)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426328.1
- HSSP:   Q5SJ29
- ProteinModelPortal:   Q2RV04
- SMR:   Q2RV04
- STRING:   Q2RV04
- GeneID:   3833738
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A1240
- NMPDR:   fig|1085.1.peg.3126
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- PhylomeDB:   Q2RV04
- ProtClustDB:   PRK12298
- BioCyc:   RRUB269796:RRU_A1240-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 41848; Mature: 41848

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDQAKIFVKSGDGGNGCVAFRREKNIEFGGPDGGHGGRGADVIVEAVPNLNTLIDFR
CCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHEECCCCHHHHHHHH
YQQHFKAARGRDGSGDNRTGKSGEATIIKVPVGTQIFEDDRKTLIADLSRPGQRVRLAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
GDGGFGNAHYKSSTNQAPRRADPGWPGQEIWVWLRLKLIADAGLIGLPNAGKSTLLAAVT
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEHHHEEHHHHCCCEEECCCCCHHHHHHHHH
RARPKIADYPFTTLHPNLGVVHQDAREFIIADIPGLIEGAHEGAGLGTRFLGHVERCAVL
HCCCCCCCCCCEEECCCCCEEEHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LHMIDATQDDVAGAWRTVRAELKGHGQGLDEKSEIVGLSKIDALPPEDIAAKIAELSEAC
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHEECHHHHCCCCHHHHHHHHHHHHHHC
GAPVMAFSAISGKGLADVLRVMATHVDEARALRHARGEAEGDASDEAMRDVTGIDHGYNR
CCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC
PSAVVDWEDAPFDDDDDDDGDESGDKGQWTR
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKFLDQAKIFVKSGDGGNGCVAFRREKNIEFGGPDGGHGGRGADVIVEAVPNLNTLIDFR
CCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHEECCCCHHHHHHHH
YQQHFKAARGRDGSGDNRTGKSGEATIIKVPVGTQIFEDDRKTLIADLSRPGQRVRLAKG
HHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEC
GDGGFGNAHYKSSTNQAPRRADPGWPGQEIWVWLRLKLIADAGLIGLPNAGKSTLLAAVT
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEHHHEEHHHHCCCEEECCCCCHHHHHHHHH
RARPKIADYPFTTLHPNLGVVHQDAREFIIADIPGLIEGAHEGAGLGTRFLGHVERCAVL
HCCCCCCCCCCEEECCCCCEEEHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
LHMIDATQDDVAGAWRTVRAELKGHGQGLDEKSEIVGLSKIDALPPEDIAAKIAELSEAC
HHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHEECHHHHCCCCHHHHHHHHHHHHHHC
GAPVMAFSAISGKGLADVLRVMATHVDEARALRHARGEAEGDASDEAMRDVTGIDHGYNR
CCCEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCC
PSAVVDWEDAPFDDDDDDDGDESGDKGQWTR
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA