Click here to switch to the map view.

The map label for this gene is ffh [H]

Identifier: 83592520

GI number: 83592520

Start: 1402159

End: 1403673

Strand: Direct

Name: ffh [H]

Synonym: Rru_A1184

Alternate gene names: 83592520

Gene position: 1402159-1403673 (Clockwise)

Preceding gene: 83592516

Following gene: 83592521

Centisome position: 32.21

GC content: 65.61

Gene sequence:

>1515_bases
ATGTTCGACGGACTGTCGGGTCGCTTGGGCGACGTTCTCGATAAACTGCGCAGACGGGGTTCCCTTTCGGAAGCCGACGT
CGATGCCGCCATGCGCGAAGTGCGCGTCGCCCTTCTCGAGGCCGACGTCGCCCTAGCCGTGGTCAAGCAGTTCGTTGCCC
AGGTCAAGGAACAGGCCATCGGCCAAGAGGTCATCCGCTCGGTCACCCCCGGGCAGATGGTGGTCAAGCTCGTTCACGAC
GCCCTGGTCGACATGCTGTCGGGCGAGGGTGGGGTCGAGGCCGAGCCCGATCCGATGTCGCTGGGCATCGATATCGCCCA
TACCCCGCCGGTGCCGATCCTGATGGTCGGCCTGCAGGGGTCGGGCAAGACCACCACCTCGGCCAAGATCGCCCTGCGCA
TCACCAAGCGCGAGCGCAAGAAGGTGCTGATGGCCTCGCTCGACGTTTACCGTCCGGCCGCCCAGCGCCAGCTCGCCATC
CTTGGCGAACAGACCGGGGTCGACACCCTGGAAGTGGTGATGGGCCAGAAGCCCGTCGAGATCGCCCGCCGCGCCATGCA
GGCGGCCCGCGTCGGCGGCTACGACGTGGTCATCCTCGATACCGCCGGCCGGCTGCATATCGACGAAGTGCTGATGACCG
AGGTCGCCGAGGTGCGCGCCCTGGTCAATCCCCACGAGGTGCTGCTGGTCACCGACGCCATGACCGGCCAGGACGCCGTC
AACGTCGCCCAGGAATTCAACGAAAAGGTCGGCGTGACCGGCATCGTGCTGACCCGGGTCGATGGCGACAGCCGCGGCGG
CGCGGCCTTGTCGATGCGGGCGGTGACCGGCGTGCCGATCAAATTGATGGGCATGGGCGAGAAGATGGACGCCCTTGAGG
CGTTCCACGCCCAGCGCATCGCCGGACGCATTCTGGGCATGGGCGACGTCGTCGCCCTGGTCGAGAAGGCGGCCGAGACC
ATCGAGATGGATCAGGCCGAACGCGTCGCCAAGCGGATGATGGAAGGCAAGTTCGACCTTGAGGACATGCTGGCCCAGAT
CCGTCAGATCAAGAAGATGGGCGACATGAAGGGCCTGCTCGGCATGATGCCCGGCATCAGCAAGATGCAGCGCCAGATGG
CCGAATCGAAGATCGACGACAACATGATGAAGCGCCAGGAGGCGATCATCTTGTCGATGACGATCAAGGAGCGTCGCAAC
CCCGATCTGGTCAAGGCCTCGCGCAAGAAGCGCATCGCCGATGGCTCGGGCTCGAACGTTCCCGAGGTCAATAAGCTTCT
GAAGCAGCACCAGCAGATGGCGGTGGTGATGAAGAAGATGAAAAAGATGGGTGGCAAGAAGGGTCTGATGGGCCTGCTTG
GCGGCATGGGCGGCGGTGGCGAGGGCGACGCGCCCGATCTGTCGGCGCTTGGCGGCGCCGGCGGCGGCCTGCCCCCCGGC
TTTCCCGGTCTCGGCGGTCCGCGCGGCGGGCTGCCCCCAGGTTTTCCCGGTCGGTTCTCCGGGAAGAAGAAGTAG

Upstream 100 bases:

>100_bases
GGAGGTCCGCCAGTCCGCGAGCATCGCGCACTGGCGATACTGTCGTTTGGCCGAATGCCGGAGCGGAAGGGCGACACCTT
TGGGAAACGGGGCGGGGACC

Downstream 100 bases:

>100_bases
TCGGATAGCGCCCAGGCGGCGCTCCGGCGTGACTATCGTTTTTTCGAGTTGATCAGGAACTTAGGAGTAAGCAAGACCAT
GTCCCTGCGAATTCGGCTTG

Product: signal recognition particle subunit FFH/SRP54 (srp54)

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MFDGLSGRLGDVLDKLRRRGSLSEADVDAAMREVRVALLEADVALAVVKQFVAQVKEQAIGQEVIRSVTPGQMVVKLVHD
ALVDMLSGEGGVEAEPDPMSLGIDIAHTPPVPILMVGLQGSGKTTTSAKIALRITKRERKKVLMASLDVYRPAAQRQLAI
LGEQTGVDTLEVVMGQKPVEIARRAMQAARVGGYDVVILDTAGRLHIDEVLMTEVAEVRALVNPHEVLLVTDAMTGQDAV
NVAQEFNEKVGVTGIVLTRVDGDSRGGAALSMRAVTGVPIKLMGMGEKMDALEAFHAQRIAGRILGMGDVVALVEKAAET
IEMDQAERVAKRMMEGKFDLEDMLAQIRQIKKMGDMKGLLGMMPGISKMQRQMAESKIDDNMMKRQEAIILSMTIKERRN
PDLVKASRKKRIADGSGSNVPEVNKLLKQHQQMAVVMKKMKKMGGKKGLMGLLGGMGGGGEGDAPDLSALGGAGGGLPPG
FPGLGGPRGGLPPGFPGRFSGKKK

Sequences:

>Translated_504_residues
MFDGLSGRLGDVLDKLRRRGSLSEADVDAAMREVRVALLEADVALAVVKQFVAQVKEQAIGQEVIRSVTPGQMVVKLVHD
ALVDMLSGEGGVEAEPDPMSLGIDIAHTPPVPILMVGLQGSGKTTTSAKIALRITKRERKKVLMASLDVYRPAAQRQLAI
LGEQTGVDTLEVVMGQKPVEIARRAMQAARVGGYDVVILDTAGRLHIDEVLMTEVAEVRALVNPHEVLLVTDAMTGQDAV
NVAQEFNEKVGVTGIVLTRVDGDSRGGAALSMRAVTGVPIKLMGMGEKMDALEAFHAQRIAGRILGMGDVVALVEKAAET
IEMDQAERVAKRMMEGKFDLEDMLAQIRQIKKMGDMKGLLGMMPGISKMQRQMAESKIDDNMMKRQEAIILSMTIKERRN
PDLVKASRKKRIADGSGSNVPEVNKLLKQHQQMAVVMKKMKKMGGKKGLMGLLGGMGGGGEGDAPDLSALGGAGGGLPPG
FPGLGGPRGGLPPGFPGRFSGKKK
>Mature_504_residues
MFDGLSGRLGDVLDKLRRRGSLSEADVDAAMREVRVALLEADVALAVVKQFVAQVKEQAIGQEVIRSVTPGQMVVKLVHD
ALVDMLSGEGGVEAEPDPMSLGIDIAHTPPVPILMVGLQGSGKTTTSAKIALRITKRERKKVLMASLDVYRPAAQRQLAI
LGEQTGVDTLEVVMGQKPVEIARRAMQAARVGGYDVVILDTAGRLHIDEVLMTEVAEVRALVNPHEVLLVTDAMTGQDAV
NVAQEFNEKVGVTGIVLTRVDGDSRGGAALSMRAVTGVPIKLMGMGEKMDALEAFHAQRIAGRILGMGDVVALVEKAAET
IEMDQAERVAKRMMEGKFDLEDMLAQIRQIKKMGDMKGLLGMMPGISKMQRQMAESKIDDNMMKRQEAIILSMTIKERRN
PDLVKASRKKRIADGSGSNVPEVNKLLKQHQQMAVVMKKMKKMGGKKGLMGLLGGMGGGGEGDAPDLSALGGAGGGLPPG
FPGLGGPRGGLPPGFPGRFSGKKK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=460, Percent_Identity=31.9565217391304, Blast_Score=202, Evalue=5e-52,
Organism=Homo sapiens, GI226371618, Length=348, Percent_Identity=33.6206896551724, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI295424842, Length=309, Percent_Identity=28.8025889967638, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI23308697, Length=309, Percent_Identity=28.8025889967638, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1788963, Length=434, Percent_Identity=50.4608294930876, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1789874, Length=194, Percent_Identity=40.2061855670103, Blast_Score=135, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17539958, Length=462, Percent_Identity=31.1688311688312, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI193206261, Length=303, Percent_Identity=29.3729372937294, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6325345, Length=418, Percent_Identity=31.8181818181818, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6320498, Length=308, Percent_Identity=24.025974025974, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17647949, Length=469, Percent_Identity=30.9168443496802, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24641198, Length=309, Percent_Identity=26.8608414239482, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 53744; Mature: 53744

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDGLSGRLGDVLDKLRRRGSLSEADVDAAMREVRVALLEADVALAVVKQFVAQVKEQAI
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVIRSVTPGQMVVKLVHDALVDMLSGEGGVEAEPDPMSLGIDIAHTPPVPILMVGLQG
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECEEECCCCCCCEEEEEECC
SGKTTTSAKIALRITKRERKKVLMASLDVYRPAAQRQLAILGEQTGVDTLEVVMGQKPVE
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHCCCCHH
IARRAMQAARVGGYDVVILDTAGRLHIDEVLMTEVAEVRALVNPHEVLLVTDAMTGQDAV
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
NVAQEFNEKVGVTGIVLTRVDGDSRGGAALSMRAVTGVPIKLMGMGEKMDALEAFHAQRI
HHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHH
AGRILGMGDVVALVEKAAETIEMDQAERVAKRMMEGKFDLEDMLAQIRQIKKMGDMKGLL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GMMPGISKMQRQMAESKIDDNMMKRQEAIILSMTIKERRNPDLVKASRKKRIADGSGSNV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCCHHHHHHHHHCCCCCCCCC
PEVNKLLKQHQQMAVVMKKMKKMGGKKGLMGLLGGMGGGGEGDAPDLSALGGAGGGLPPG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCC
FPGLGGPRGGLPPGFPGRFSGKKK
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDGLSGRLGDVLDKLRRRGSLSEADVDAAMREVRVALLEADVALAVVKQFVAQVKEQAI
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GQEVIRSVTPGQMVVKLVHDALVDMLSGEGGVEAEPDPMSLGIDIAHTPPVPILMVGLQG
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECEEECCCCCCCEEEEEECC
SGKTTTSAKIALRITKRERKKVLMASLDVYRPAAQRQLAILGEQTGVDTLEVVMGQKPVE
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHCCCCHH
IARRAMQAARVGGYDVVILDTAGRLHIDEVLMTEVAEVRALVNPHEVLLVTDAMTGQDAV
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHH
NVAQEFNEKVGVTGIVLTRVDGDSRGGAALSMRAVTGVPIKLMGMGEKMDALEAFHAQRI
HHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHH
AGRILGMGDVVALVEKAAETIEMDQAERVAKRMMEGKFDLEDMLAQIRQIKKMGDMKGLL
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GMMPGISKMQRQMAESKIDDNMMKRQEAIILSMTIKERRNPDLVKASRKKRIADGSGSNV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCCHHHHHHHHHCCCCCCCCC
PEVNKLLKQHQQMAVVMKKMKKMGGKKGLMGLLGGMGGGGEGDAPDLSALGGAGGGLPPG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCC
FPGLGGPRGGLPPGFPGRFSGKKK
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]