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The map label for this gene is glcR [H]

Identifier: 83592515

GI number: 83592515

Start: 1395992

End: 1396756

Strand: Direct

Name: glcR [H]

Synonym: Rru_A1179

Alternate gene names: 83592515

Gene position: 1395992-1396756 (Clockwise)

Preceding gene: 83592514

Following gene: 83592516

Centisome position: 32.07

GC content: 70.98

Gene sequence:

>765_bases
ATGGGCCCGCTTTCCAATGATGAACGCCGCGCCGCGGTTCTCGAGCGCCTGCGCGCCGAGGGTCGGGTTGGCGTGGCGGA
TTTGGCGCAGGTGTTTTCCACCTCGGAAGACAGCATCCGCCGCGACCTGCGCGATATGGCCGCGGCCGGACTGCTGCGCC
GGGTCCATGGCGGCGCCATCCCGGTTTCCCCCGCCCAGGGCGATTTCGGCGAGCGCGCCCGACGTGACGGCCCGGCCAAG
GACGCCCTGGGCCGGGCGGCGGCGGCGCTGATCGGCGGCGGACAAACCGTGCTGATCGATGGCGGAACGACGCTGCTGGC
CGTCGCCCGGGCCATCCCCGGCGGGCTGGGGGTGACGATCATCACCAGCGCTCCGGCGATCGGCCTTGAACTTGTCGATC
GTCCGGGGCTCGAGGTGATCGTGCTGGGCGGGCGGCTTGACCGGGCGACGCGCACGGTCAGCGGCGCGGCGGTGGTCGAG
GCGGTGGGGCGGATCAACGCCGATCTCTGCCTGCTTGGCATCTGTGGCCTTGAGGCCGGGGCGGGGGTCAGCGCCAGCGA
TTACGAGGAGGCCCAGGTTAAGCGGGCGATGGTCGCGGCCTCGCGCCAAGTGGTCGCCGTTACCACCGCCGACAAGCTGG
GAACGGCCGCCCCCCATTGGGTTTGCCCGGCCGGGCGCCTGGACAAGATCGTGATGGACGGGGTCGGCGACGAGGCGGCG
ATCGAGGCGCTCGCCTTGCAAGGTGTTGATATGGTGAGGATATGA

Upstream 100 bases:

>100_bases
CGCCCGCCGGCTTCATCCGCCGGCGGGCGATCGACGGCTCTTGACGATTTTCGCCTGGCAGTGCATGTTTTTGCCGATTT
AGGCAAAAACAGGAGACACC

Downstream 100 bases:

>100_bases
TGGATCAAAGGACCGCCCTGGGGGAAGCCCAGGGGCGTCGGGCGCGCGGAGCGGTTGGCGTGTTGTTTCTGACCAACGGC
ATGGCCTTGGGCCTGTGGTC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MGPLSNDERRAAVLERLRAEGRVGVADLAQVFSTSEDSIRRDLRDMAAAGLLRRVHGGAIPVSPAQGDFGERARRDGPAK
DALGRAAAALIGGGQTVLIDGGTTLLAVARAIPGGLGVTIITSAPAIGLELVDRPGLEVIVLGGRLDRATRTVSGAAVVE
AVGRINADLCLLGICGLEAGAGVSASDYEEAQVKRAMVAASRQVVAVTTADKLGTAAPHWVCPAGRLDKIVMDGVGDEAA
IEALALQGVDMVRI

Sequences:

>Translated_254_residues
MGPLSNDERRAAVLERLRAEGRVGVADLAQVFSTSEDSIRRDLRDMAAAGLLRRVHGGAIPVSPAQGDFGERARRDGPAK
DALGRAAAALIGGGQTVLIDGGTTLLAVARAIPGGLGVTIITSAPAIGLELVDRPGLEVIVLGGRLDRATRTVSGAAVVE
AVGRINADLCLLGICGLEAGAGVSASDYEEAQVKRAMVAASRQVVAVTTADKLGTAAPHWVCPAGRLDKIVMDGVGDEAA
IEALALQGVDMVRI
>Mature_253_residues
GPLSNDERRAAVLERLRAEGRVGVADLAQVFSTSEDSIRRDLRDMAAAGLLRRVHGGAIPVSPAQGDFGERARRDGPAKD
ALGRAAAALIGGGQTVLIDGGTTLLAVARAIPGGLGVTIITSAPAIGLELVDRPGLEVIVLGGRLDRATRTVSGAAVVEA
VGRINADLCLLGICGLEAGAGVSASDYEEAQVKRAMVAASRQVVAVTTADKLGTAAPHWVCPAGRLDKIVMDGVGDEAAI
EALALQGVDMVRI

Specific function: Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=27.3809523809524, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789829, Length=215, Percent_Identity=30.2325581395349, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=27.4193548387097, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787540, Length=229, Percent_Identity=27.9475982532751, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=29.3172690763052, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788069, Length=229, Percent_Identity=23.5807860262009, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082344, Length=218, Percent_Identity=28.4403669724771, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787063, Length=249, Percent_Identity=22.4899598393574, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789170, Length=197, Percent_Identity=24.3654822335025, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790635, Length=259, Percent_Identity=22.7799227799228, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 25909; Mature: 25778

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPLSNDERRAAVLERLRAEGRVGVADLAQVFSTSEDSIRRDLRDMAAAGLLRRVHGGAI
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PVSPAQGDFGERARRDGPAKDALGRAAAALIGGGQTVLIDGGTTLLAVARAIPGGLGVTI
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCEEE
ITSAPAIGLELVDRPGLEVIVLGGRLDRATRTVSGAAVVEAVGRINADLCLLGICGLEAG
EECCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
AGVSASDYEEAQVKRAMVAASRQVVAVTTADKLGTAAPHWVCPAGRLDKIVMDGVGDEAA
CCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHH
IEALALQGVDMVRI
HHHHHHCCCHHCCC
>Mature Secondary Structure 
GPLSNDERRAAVLERLRAEGRVGVADLAQVFSTSEDSIRRDLRDMAAAGLLRRVHGGAI
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
PVSPAQGDFGERARRDGPAKDALGRAAAALIGGGQTVLIDGGTTLLAVARAIPGGLGVTI
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCEEE
ITSAPAIGLELVDRPGLEVIVLGGRLDRATRTVSGAAVVEAVGRINADLCLLGICGLEAG
EECCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
AGVSASDYEEAQVKRAMVAASRQVVAVTTADKLGTAAPHWVCPAGRLDKIVMDGVGDEAA
CCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHH
IEALALQGVDMVRI
HHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]