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The map label for this gene is pyc [H]

Identifier: 83592457

GI number: 83592457

Start: 1320030

End: 1323491

Strand: Direct

Name: pyc [H]

Synonym: Rru_A1121

Alternate gene names: 83592457

Gene position: 1320030-1323491 (Clockwise)

Preceding gene: 83592456

Following gene: 83592458

Centisome position: 30.33

GC content: 64.88

Gene sequence:

>3462_bases
ATGACGAGTCAGTCTCCGAGAAAGATCACCAAGATCCTTGTCGCCAATCGGGGCGAGATCGCCATTCGCGTGTTCCGCGC
GGCCAATGAATCGGGGATCCGCACCGTCGCCATCTATGCCGAGGAGGACAAGCTGTCGCTCCATCGGTTCAAGGCCGACG
AAAGCTATCTGATCGGCACCGGCATGGGCCCGGTGCGGGCCTATCTGTCGATCGACGAGATCCTGCGCGTCGCCCGGCAA
AGCGGCGCCGACGCCATCCACCCCGGCTATGGCTTCTTGTCGGAGAACCCCGAGTTCGCCGAGGCCTGCGCCGAGGCCGG
GCTGATCTTCATCGGTCCGCCGCCCGAGGTCATGCGCTCGCTTGGCAACAAAGTCTCGGCGCGCGCCATGGCCGAGGCCG
CCGATGTGCCGGTGATGCCGGCCACCGGCCCCCTGCCCGAGGAGATCGACCTCATCCGCCCGATGGCCGAAAAGGTCGGC
TATCCCCTGATGCTCAAGGCGTCGTGGGGCGGCGGTGGGCGCGGCATGCGGGTGATCAACACCCCCGACGAGTTGGAGCG
TCAGGTCTCGGCCGGCCGGCGCGAGGCCGAAGCCGCCTTCGGCAATGGCGAGGTCTATCTGGAAAAGCTGGTGCTGCGCG
CCCGCCATGTCGAAGTGCAGTTGCTCGGCGATCATTACGGCACGGTTGTTCATTTGTTCGAGCGCGATTGTTCGGTCCAG
CGCCGCAACCAGAAGGTCGTCGAGCGGGCGCCGGCCCCCTATCTGACCCCCGAAAAGCGCGAGGAGGTCTGCGAGGCCGC
CCTGCGGCTGGCGCGGGCGGCGGGCTATGTTTGCGCCGGAACGGCCGAATTCCTGATGGATGCCGATACGGGTGACTTCC
ATTTCATCGAAGTCAATCCCCGCATCCAGGTTGAACATACGGTGACCGAGGAGGTCACCGGCATCGATCTGGTCAAGGCC
CAGATCCGCATTTGCGAAGGCGGCCATATCGGCGTCGTCGAGGAAACCGGCGTGCCGGCCCAGGCCGATCTGCGGCTGCA
GGGCCATGCCATTCAATGCCGGATCACCACCGAGGATCCGGAAGCCAATTTCATCCCCGATTACGGCCGCATCACCGCTT
ATCGCGGGGCGACGGGCTTTGGCATCCGCCTGGATGGCGGCACGGCCTATTCGGGGGCGGTGATCACCCGCTATTACGAC
AGCTTGCTGGAAAAGGTCACCGCCTGGGCGCCGACGCCCAAGGAGGCCATCGACCGCCTGGACCGCGCCCTGCGCGAATT
CCGCATTCGCGGCGTGGCGACCAATCTGGCCTTCGTCGAGAACCTGATCAACCATCCGAAGTTCCGCGAGGCGTCTTATA
CCACCCGCTTCATCGACGAGACGCCCGAGCTGTTCCACTTCGACCGCCGCCTTGACCGGGCGACCAAGCTTTTGCGCTTC
ATCGCCGATGTGACGGTCAACGGCAATCCCGAGGTCAAGGGCCGGGTTCTGCCCACCCCCGGACCGGCGCCGCGCCTGCC
GATCGTCCAGGCCCAGGAGCCGCCGCGCGGCACCCGCCAGATCCTGGCCGAACTGGGGCCGACCGGTTTTGCCGAATGGA
TGCTTGACCAGAAGCGCACCCTGGTCACCGACACCACCTTCCGCGATGCCCATCAGTCGCTGCTCGCCACCCGCATGCGC
AGCTTCGACATGATCCAGGTCGCCGATGCCTATGCCCGCAATCTGCCCGAGCTTTTCAGCCTGGAATGCTGGGGCGGCGC
CACCTTCGATGTCGCCATGCGCTTCTTGCGCGAATGCCCCTGGGAGCGGCTGGCCGAACTGCGCCAGCGCGTGCCCAATA
TCTTGTTCCAAATGCTGCTGCGCGGCGCCAATGGCGTTGGCTATACCGTTTATCCCGACAATGTGGTCAAGGGCTTCACC
CATAAGGCGGCCGAGGCCGGCGTCGATCTGTTCCGGGTGTTCGACAGCCTGAACTGGGTCGAGAATATGCGCGTCTCAAT
GGACGCTGTGCTTGAAACCGGCAAGCTGCTCGAAGGCGTGGTCTGCTACACCGGCGATATCAACGATCCCGAGCGCAGCA
AATACGACCTTAAATACTATGTTTCGATGGCCCGCGAACTGCGGAAGGCCGGCAGCCATATCATCGGCATCAAGGACATG
GCCGGTCTGGTCAAGCCGCGCGCCGCCTATGCCCTGGTCAAGGCGCTGAAAGAGGAAACCGGCCTGCCGGTGCATTTCCA
CACCCACGACACCAGCGGCATCAGCGCCGCCAGCGTGCTGGAGGCCGTGCGCGCCGGGGTCGATGCGATCGACGCGGCGA
TGGACAGCTTCTCGGGGCTGACCAGCCAGCCCTGCCTGGGCTCGATCGTCGAAGCCCTGCGCTTTTCCGAACGCGATACC
GGGCTTGATCCGCTCATCGTCCGTCAGGTCAGCGATTATTGGGAAGGGGTGCGCCGCCAGTACGCCGGCTTTGAAAGTGA
TCTGCGCTCCGGGGCCTCGGAGGTGTATCTCCACGAAATGCCCGGCGGCCAGTTCACCAATCTGAAGGAGCAGGCCCGCG
CCATGGGGCTGGCCGGCCATTGGCACGAGGTGGCGCGCACCTATGCCGAGGTCAATCAGATGTTTGGCGATATCGTCAAG
GTGACGCCGTCATCCAAGGTGGTCGGCGACATGGCGCTTTATATGGTTGGCGCCGGGCTGACCCGCGCCGATGTCGAGGA
CCCCGACAAGGACGTGAGCTTCCCCGAAAGCGTCGTTAGCCTGATGCGCGGTGAGCTGGGTCATCCGCCCGAGGGCTTCC
CCGAAGCCCTTCAGCGCAAGGTTCTGCGCGGTCAGGCGCCGTTGGCGGGCCGCCCGGGCGCGGCGGTGCCGCCGGCCGAT
CTGGCCGCCGAGCGCAAGACCGCCGAGGAAAAGGCCGGACGGGCGATCAGCGACGAGGAATTCCAGTCCTATCTGATGTA
CCCCAAGGTGTTCATCGACTACGCCAAGCAGCGCGCCGAATTTGGTCCGGTGCGCGTGCTGCCGACGCCGATCTTCTTCT
ATGGCATGAAGCCCGGCCAGGAGACCGCCGTCACCCTGGAAGCCGGCAAGACCCTGGTGATCCGCTGTCAGGCCCTGGGC
GAGACCGATGAAGAGGGGATGATCAAGGTTTTCTTCGAACTGAATGGCCAGCCGCGCGTTGTGCGCGTGGTTAACCGAGC
GGTCAAATCGACGGTCATCCAGCATGAAAAGGCCGATCCGGCCAATCCCACCCATGTCGCCTGCCCGATGCCCGGCTTGG
TCTCGTCGGTTGGCGTGAGCGTCGGGCAGACGGTACGGGCGGGCGATCCGCTGCTGACCATCGAGGCGATGAAGATGGAA
ACCTCGATCACCGCCGAACGCGCCGGGGTGATCGAACGCCTGCCGATCGCCGCCGGCACCGCGGTGGAAGCCAAGGACCT
GCTGGTCGTCTACAAGGGCTGA

Upstream 100 bases:

>100_bases
GCCTCTCCCTTGCAATCGCCTGATCAACTCAGCATTCTTGCCGCGCCGCAACACATGCGGGTTTTCCCGTCGATCCGTTC
TTAAGAAAGATCCTCCCGAC

Downstream 100 bases:

>100_bases
GCCTGGGGCAAGGGGGCTTCGGCCCCCTTTTTCCCCCAAGGATCTTCTGATGTCCGATCACTTCGACGGAACGCGTTTTT
TCAATCCGGGACGCCCGGAA

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1153; Mature: 1152

Protein sequence:

>1153_residues
MTSQSPRKITKILVANRGEIAIRVFRAANESGIRTVAIYAEEDKLSLHRFKADESYLIGTGMGPVRAYLSIDEILRVARQ
SGADAIHPGYGFLSENPEFAEACAEAGLIFIGPPPEVMRSLGNKVSARAMAEAADVPVMPATGPLPEEIDLIRPMAEKVG
YPLMLKASWGGGGRGMRVINTPDELERQVSAGRREAEAAFGNGEVYLEKLVLRARHVEVQLLGDHYGTVVHLFERDCSVQ
RRNQKVVERAPAPYLTPEKREEVCEAALRLARAAGYVCAGTAEFLMDADTGDFHFIEVNPRIQVEHTVTEEVTGIDLVKA
QIRICEGGHIGVVEETGVPAQADLRLQGHAIQCRITTEDPEANFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRYYD
SLLEKVTAWAPTPKEAIDRLDRALREFRIRGVATNLAFVENLINHPKFREASYTTRFIDETPELFHFDRRLDRATKLLRF
IADVTVNGNPEVKGRVLPTPGPAPRLPIVQAQEPPRGTRQILAELGPTGFAEWMLDQKRTLVTDTTFRDAHQSLLATRMR
SFDMIQVADAYARNLPELFSLECWGGATFDVAMRFLRECPWERLAELRQRVPNILFQMLLRGANGVGYTVYPDNVVKGFT
HKAAEAGVDLFRVFDSLNWVENMRVSMDAVLETGKLLEGVVCYTGDINDPERSKYDLKYYVSMARELRKAGSHIIGIKDM
AGLVKPRAAYALVKALKEETGLPVHFHTHDTSGISAASVLEAVRAGVDAIDAAMDSFSGLTSQPCLGSIVEALRFSERDT
GLDPLIVRQVSDYWEGVRRQYAGFESDLRSGASEVYLHEMPGGQFTNLKEQARAMGLAGHWHEVARTYAEVNQMFGDIVK
VTPSSKVVGDMALYMVGAGLTRADVEDPDKDVSFPESVVSLMRGELGHPPEGFPEALQRKVLRGQAPLAGRPGAAVPPAD
LAAERKTAEEKAGRAISDEEFQSYLMYPKVFIDYAKQRAEFGPVRVLPTPIFFYGMKPGQETAVTLEAGKTLVIRCQALG
ETDEEGMIKVFFELNGQPRVVRVVNRAVKSTVIQHEKADPANPTHVACPMPGLVSSVGVSVGQTVRAGDPLLTIEAMKME
TSITAERAGVIERLPIAAGTAVEAKDLLVVYKG

Sequences:

>Translated_1153_residues
MTSQSPRKITKILVANRGEIAIRVFRAANESGIRTVAIYAEEDKLSLHRFKADESYLIGTGMGPVRAYLSIDEILRVARQ
SGADAIHPGYGFLSENPEFAEACAEAGLIFIGPPPEVMRSLGNKVSARAMAEAADVPVMPATGPLPEEIDLIRPMAEKVG
YPLMLKASWGGGGRGMRVINTPDELERQVSAGRREAEAAFGNGEVYLEKLVLRARHVEVQLLGDHYGTVVHLFERDCSVQ
RRNQKVVERAPAPYLTPEKREEVCEAALRLARAAGYVCAGTAEFLMDADTGDFHFIEVNPRIQVEHTVTEEVTGIDLVKA
QIRICEGGHIGVVEETGVPAQADLRLQGHAIQCRITTEDPEANFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRYYD
SLLEKVTAWAPTPKEAIDRLDRALREFRIRGVATNLAFVENLINHPKFREASYTTRFIDETPELFHFDRRLDRATKLLRF
IADVTVNGNPEVKGRVLPTPGPAPRLPIVQAQEPPRGTRQILAELGPTGFAEWMLDQKRTLVTDTTFRDAHQSLLATRMR
SFDMIQVADAYARNLPELFSLECWGGATFDVAMRFLRECPWERLAELRQRVPNILFQMLLRGANGVGYTVYPDNVVKGFT
HKAAEAGVDLFRVFDSLNWVENMRVSMDAVLETGKLLEGVVCYTGDINDPERSKYDLKYYVSMARELRKAGSHIIGIKDM
AGLVKPRAAYALVKALKEETGLPVHFHTHDTSGISAASVLEAVRAGVDAIDAAMDSFSGLTSQPCLGSIVEALRFSERDT
GLDPLIVRQVSDYWEGVRRQYAGFESDLRSGASEVYLHEMPGGQFTNLKEQARAMGLAGHWHEVARTYAEVNQMFGDIVK
VTPSSKVVGDMALYMVGAGLTRADVEDPDKDVSFPESVVSLMRGELGHPPEGFPEALQRKVLRGQAPLAGRPGAAVPPAD
LAAERKTAEEKAGRAISDEEFQSYLMYPKVFIDYAKQRAEFGPVRVLPTPIFFYGMKPGQETAVTLEAGKTLVIRCQALG
ETDEEGMIKVFFELNGQPRVVRVVNRAVKSTVIQHEKADPANPTHVACPMPGLVSSVGVSVGQTVRAGDPLLTIEAMKME
TSITAERAGVIERLPIAAGTAVEAKDLLVVYKG
>Mature_1152_residues
TSQSPRKITKILVANRGEIAIRVFRAANESGIRTVAIYAEEDKLSLHRFKADESYLIGTGMGPVRAYLSIDEILRVARQS
GADAIHPGYGFLSENPEFAEACAEAGLIFIGPPPEVMRSLGNKVSARAMAEAADVPVMPATGPLPEEIDLIRPMAEKVGY
PLMLKASWGGGGRGMRVINTPDELERQVSAGRREAEAAFGNGEVYLEKLVLRARHVEVQLLGDHYGTVVHLFERDCSVQR
RNQKVVERAPAPYLTPEKREEVCEAALRLARAAGYVCAGTAEFLMDADTGDFHFIEVNPRIQVEHTVTEEVTGIDLVKAQ
IRICEGGHIGVVEETGVPAQADLRLQGHAIQCRITTEDPEANFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRYYDS
LLEKVTAWAPTPKEAIDRLDRALREFRIRGVATNLAFVENLINHPKFREASYTTRFIDETPELFHFDRRLDRATKLLRFI
ADVTVNGNPEVKGRVLPTPGPAPRLPIVQAQEPPRGTRQILAELGPTGFAEWMLDQKRTLVTDTTFRDAHQSLLATRMRS
FDMIQVADAYARNLPELFSLECWGGATFDVAMRFLRECPWERLAELRQRVPNILFQMLLRGANGVGYTVYPDNVVKGFTH
KAAEAGVDLFRVFDSLNWVENMRVSMDAVLETGKLLEGVVCYTGDINDPERSKYDLKYYVSMARELRKAGSHIIGIKDMA
GLVKPRAAYALVKALKEETGLPVHFHTHDTSGISAASVLEAVRAGVDAIDAAMDSFSGLTSQPCLGSIVEALRFSERDTG
LDPLIVRQVSDYWEGVRRQYAGFESDLRSGASEVYLHEMPGGQFTNLKEQARAMGLAGHWHEVARTYAEVNQMFGDIVKV
TPSSKVVGDMALYMVGAGLTRADVEDPDKDVSFPESVVSLMRGELGHPPEGFPEALQRKVLRGQAPLAGRPGAAVPPADL
AAERKTAEEKAGRAISDEEFQSYLMYPKVFIDYAKQRAEFGPVRVLPTPIFFYGMKPGQETAVTLEAGKTLVIRCQALGE
TDEEGMIKVFFELNGQPRVVRVVNRAVKSTVIQHEKADPANPTHVACPMPGLVSSVGVSVGQTVRAGDPLLTIEAMKMET
SITAERAGVIERLPIAAGTAVEAKDLLVVYKG

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1147, Percent_Identity=49.4333042720139, Blast_Score=1089, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1147, Percent_Identity=49.4333042720139, Blast_Score=1089, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1147, Percent_Identity=49.4333042720139, Blast_Score=1089, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=470, Percent_Identity=43.6170212765958, Blast_Score=401, Evalue=1e-111,
Organism=Homo sapiens, GI65506442, Length=462, Percent_Identity=39.8268398268398, Blast_Score=336, Evalue=1e-91,
Organism=Homo sapiens, GI189095269, Length=462, Percent_Identity=39.8268398268398, Blast_Score=335, Evalue=1e-91,
Organism=Homo sapiens, GI295821183, Length=462, Percent_Identity=39.8268398268398, Blast_Score=335, Evalue=1e-91,
Organism=Homo sapiens, GI38679960, Length=503, Percent_Identity=32.0079522862823, Blast_Score=251, Evalue=3e-66,
Organism=Homo sapiens, GI38679977, Length=503, Percent_Identity=32.0079522862823, Blast_Score=251, Evalue=3e-66,
Organism=Homo sapiens, GI38679967, Length=503, Percent_Identity=32.0079522862823, Blast_Score=251, Evalue=3e-66,
Organism=Homo sapiens, GI38679974, Length=503, Percent_Identity=32.0079522862823, Blast_Score=251, Evalue=4e-66,
Organism=Homo sapiens, GI38679971, Length=503, Percent_Identity=32.0079522862823, Blast_Score=250, Evalue=4e-66,
Organism=Homo sapiens, GI134142062, Length=507, Percent_Identity=32.1499013806706, Blast_Score=246, Evalue=1e-64,
Organism=Escherichia coli, GI1789654, Length=453, Percent_Identity=44.5916114790287, Blast_Score=358, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI17562816, Length=1149, Percent_Identity=50.1305483028721, Blast_Score=1121, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=462, Percent_Identity=45.2380952380952, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17567343, Length=463, Percent_Identity=39.7408207343413, Blast_Score=325, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI133931226, Length=498, Percent_Identity=29.3172690763052, Blast_Score=218, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI71997168, Length=512, Percent_Identity=28.90625, Blast_Score=208, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71997163, Length=512, Percent_Identity=28.90625, Blast_Score=208, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1158, Percent_Identity=47.2366148531952, Blast_Score=1024, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1158, Percent_Identity=47.4093264248705, Blast_Score=1013, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=448, Percent_Identity=37.7232142857143, Blast_Score=314, Evalue=5e-86,
Organism=Saccharomyces cerevisiae, GI6324343, Length=513, Percent_Identity=31.7738791423002, Blast_Score=245, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6323863, Length=480, Percent_Identity=32.0833333333333, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24652212, Length=1153, Percent_Identity=49.4362532523851, Blast_Score=1107, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1153, Percent_Identity=49.4362532523851, Blast_Score=1107, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1153, Percent_Identity=49.4362532523851, Blast_Score=1107, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1153, Percent_Identity=49.4362532523851, Blast_Score=1107, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1153, Percent_Identity=49.4362532523851, Blast_Score=1107, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1169, Percent_Identity=48.759623609923, Blast_Score=1103, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1169, Percent_Identity=48.759623609923, Blast_Score=1103, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1169, Percent_Identity=48.759623609923, Blast_Score=1103, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1169, Percent_Identity=48.759623609923, Blast_Score=1103, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1169, Percent_Identity=48.759623609923, Blast_Score=1103, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=462, Percent_Identity=43.2900432900433, Blast_Score=385, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24651759, Length=415, Percent_Identity=42.1686746987952, Blast_Score=340, Evalue=3e-93,
Organism=Drosophila melanogaster, GI161076409, Length=502, Percent_Identity=32.4701195219124, Blast_Score=248, Evalue=1e-65,
Organism=Drosophila melanogaster, GI24586458, Length=502, Percent_Identity=32.4701195219124, Blast_Score=248, Evalue=2e-65,
Organism=Drosophila melanogaster, GI161076407, Length=502, Percent_Identity=32.4701195219124, Blast_Score=248, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586460, Length=502, Percent_Identity=32.4701195219124, Blast_Score=248, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 126708; Mature: 126577

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQSPRKITKILVANRGEIAIRVFRAANESGIRTVAIYAEEDKLSLHRFKADESYLIGT
CCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCHHEECCCCCEEEEC
GMGPVRAYLSIDEILRVARQSGADAIHPGYGFLSENPEFAEACAEAGLIFIGPPPEVMRS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHH
LGNKVSARAMAEAADVPVMPATGPLPEEIDLIRPMAEKVGYPLMLKASWGGGGRGMRVIN
HCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEC
TPDELERQVSAGRREAEAAFGNGEVYLEKLVLRARHVEVQLLGDHYGTVVHLFERDCSVQ
CHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHCCHHH
RRNQKVVERAPAPYLTPEKREEVCEAALRLARAAGYVCAGTAEFLMDADTGDFHFIEVNP
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCHHHHEECCCCCEEEEEECC
RIQVEHTVTEEVTGIDLVKAQIRICEGGHIGVVEETGVPAQADLRLQGHAIQCRITTEDP
EEEEEEEHHHHHCCHHHEEEEEEEECCCCEEEEECCCCCCCCCEEEECEEEEEEEECCCC
EANFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRYYDSLLEKVTAWAPTPKEAIDRL
CCCCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
DRALREFRIRGVATNLAFVENLINHPKFREASYTTRFIDETPELFHFDRRLDRATKLLRF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
IADVTVNGNPEVKGRVLPTPGPAPRLPIVQAQEPPRGTRQILAELGPTGFAEWMLDQKRT
HHHCEECCCCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCE
LVTDTTFRDAHQSLLATRMRSFDMIQVADAYARNLPELFSLECWGGATFDVAMRFLRECP
EEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHEEECCCCCHHHHHHHHHHHCC
WERLAELRQRVPNILFQMLLRGANGVGYTVYPDNVVKGFTHKAAEAGVDLFRVFDSLNWV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENMRVSMDAVLETGKLLEGVVCYTGDINDPERSKYDLKYYVSMARELRKAGSHIIGIKDM
HHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHH
AGLVKPRAAYALVKALKEETGLPVHFHTHDTSGISAASVLEAVRAGVDAIDAAMDSFSGL
HHHHCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCC
TSQPCLGSIVEALRFSERDTGLDPLIVRQVSDYWEGVRRQYAGFESDLRSGASEVYLHEM
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEC
PGGQFTNLKEQARAMGLAGHWHEVARTYAEVNQMFGDIVKVTPSSKVVGDMALYMVGAGL
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCC
TRADVEDPDKDVSFPESVVSLMRGELGHPPEGFPEALQRKVLRGQAPLAGRPGAAVPPAD
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHH
LAAERKTAEEKAGRAISDEEFQSYLMYPKVFIDYAKQRAEFGPVRVLPTPIFFYGMKPGQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCC
ETAVTLEAGKTLVIRCQALGETDEEGMIKVFFELNGQPRVVRVVNRAVKSTVIQHEKADP
CCEEEEECCCEEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
ANPTHVACPMPGLVSSVGVSVGQTVRAGDPLLTIEAMKMETSITAERAGVIERLPIAAGT
CCCCEEECCCCHHHHHHHHHHCCEEECCCCEEEEEEEHHHHHHHHHHHCHHHHCCCCCCC
AVEAKDLLVVYKG
CCCCCCEEEEECC
>Mature Secondary Structure 
TSQSPRKITKILVANRGEIAIRVFRAANESGIRTVAIYAEEDKLSLHRFKADESYLIGT
CCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCHHEECCCCCEEEEC
GMGPVRAYLSIDEILRVARQSGADAIHPGYGFLSENPEFAEACAEAGLIFIGPPPEVMRS
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCHHHHHH
LGNKVSARAMAEAADVPVMPATGPLPEEIDLIRPMAEKVGYPLMLKASWGGGGRGMRVIN
HCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEC
TPDELERQVSAGRREAEAAFGNGEVYLEKLVLRARHVEVQLLGDHYGTVVHLFERDCSVQ
CHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHCCHHH
RRNQKVVERAPAPYLTPEKREEVCEAALRLARAAGYVCAGTAEFLMDADTGDFHFIEVNP
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCHHHHEECCCCCEEEEEECC
RIQVEHTVTEEVTGIDLVKAQIRICEGGHIGVVEETGVPAQADLRLQGHAIQCRITTEDP
EEEEEEEHHHHHCCHHHEEEEEEEECCCCEEEEECCCCCCCCCEEEECEEEEEEEECCCC
EANFIPDYGRITAYRGATGFGIRLDGGTAYSGAVITRYYDSLLEKVTAWAPTPKEAIDRL
CCCCCCCCCCEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
DRALREFRIRGVATNLAFVENLINHPKFREASYTTRFIDETPELFHFDRRLDRATKLLRF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
IADVTVNGNPEVKGRVLPTPGPAPRLPIVQAQEPPRGTRQILAELGPTGFAEWMLDQKRT
HHHCEECCCCCCCCEEECCCCCCCCCCEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCE
LVTDTTFRDAHQSLLATRMRSFDMIQVADAYARNLPELFSLECWGGATFDVAMRFLRECP
EEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHEEECCCCCHHHHHHHHHHHCC
WERLAELRQRVPNILFQMLLRGANGVGYTVYPDNVVKGFTHKAAEAGVDLFRVFDSLNWV
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENMRVSMDAVLETGKLLEGVVCYTGDINDPERSKYDLKYYVSMARELRKAGSHIIGIKDM
HHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHH
AGLVKPRAAYALVKALKEETGLPVHFHTHDTSGISAASVLEAVRAGVDAIDAAMDSFSGL
HHHHCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCC
TSQPCLGSIVEALRFSERDTGLDPLIVRQVSDYWEGVRRQYAGFESDLRSGASEVYLHEM
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEEC
PGGQFTNLKEQARAMGLAGHWHEVARTYAEVNQMFGDIVKVTPSSKVVGDMALYMVGAGL
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHCCCC
TRADVEDPDKDVSFPESVVSLMRGELGHPPEGFPEALQRKVLRGQAPLAGRPGAAVPPAD
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHH
LAAERKTAEEKAGRAISDEEFQSYLMYPKVFIDYAKQRAEFGPVRVLPTPIFFYGMKPGQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCC
ETAVTLEAGKTLVIRCQALGETDEEGMIKVFFELNGQPRVVRVVNRAVKSTVIQHEKADP
CCEEEEECCCEEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
ANPTHVACPMPGLVSSVGVSVGQTVRAGDPLLTIEAMKMETSITAERAGVIERLPIAAGT
CCCCEEECCCCHHHHHHHHHHCCEEECCCCEEEEEEEHHHHHHHHHHHCHHHHCCCCCCC
AVEAKDLLVVYKG
CCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]