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The map label for this gene is yccK [H]

Identifier: 83592395

GI number: 83592395

Start: 1252513

End: 1253496

Strand: Reverse

Name: yccK [H]

Synonym: Rru_A1059

Alternate gene names: 83592395

Gene position: 1253496-1252513 (Counterclockwise)

Preceding gene: 83592406

Following gene: 83592392

Centisome position: 28.8

GC content: 67.68

Gene sequence:

>984_bases
ATGGATTCCCTTCCCCTCGGATCTTCCGGCCTGCGCTGCTCGGCCCTTGGCCTCGGCTGCATGGGCATGTCGGAATTCTA
TGGCCCAAGCGACGACGCCCGCTCGCTGGCCACCCTGGAGGCCGCCGTGGAGCAGGGGATCACCCTGTTCGATACGGCCG
ATATGTATGGCGCCGGCCACAATGAGACGCTGCTGGGCGGCTTTCTCAAGGGGCGGCGTGACAAGGTGGTTCTGGCGACG
AAATTCGCCATTGTCCGGCCAACGGCGGCCTATGCGCGGACCATCGACAACAGCCCGGCCTATGTGCGCTCGGCCTGCGA
GGCCTCGTTGCGCCGCTTGGGCATCGACACCATCGATCTTTATTACGTCCACCGCCGCAACCCGCAAACGCCGCTGGAAG
ACACCCTGGGGGCTTTGGCCGAATTGAAGGCCGAGGGCAAGATCCGCGCCGTCGGCCTGTCGGAGGTGTCGGCCCAAACC
CTGCGCGCCGCCCATGCGATTTTGCCGATCGCCGCCGTGCAAAGCGAATATTCGCTGTGGACCCGCGATGCCGAGGCCGA
GGTGCTGGCAGCCTGCGCCGAATTGGGTATCACCTTTGTCGCCTATAGCCCGCTGGGCCGGGCGGCCCTGACCGGGGCGA
TCACTCCGACCACCCTGGTCGAGGGCGATTTTCGCCGGGCGATGCCGCGCTTTGGCGCCGAGGCCTGGGCGGTCAACCGG
CCGCTGGTCGAAGCCCTGGGCGATTTCGCCAGCGCCCGCGGCGCGACGCCGGCCCAGGTCGCCCTGGCTTGGCTTTTGGG
GCGCCCCCAGCCCCTGGTGCCGATTTTCGGCACCCGTAGCCCCGAACGCCTGCGCGAGAATATCGGCGCGGCCGCCCTGC
GCCTTTCGGCCGACGACCGCGCCATCCTCGACGCCCTGTTCCCCCCCGGCATCGCCCAGGGCATGCGCTATACCGAAGAG
GGCATGAAAAACCTCGACGTCTAA

Upstream 100 bases:

>100_bases
AATTCCCTTCATCGGTTCACGTCAAACAGGGTGGATTATCGAACAATAGGCCGACTGCTATCTCTCGTCCCCGCCTTTCG
CGATGTCAGGAGAATACGCT

Downstream 100 bases:

>100_bases
AAACTACCGTCTTCGCGTCTCTGCGAACACCGCCCGCACCGCTTCTGGAATCGGCACGGGGCGGGCGGTGTCGCGGTCGA
CGAAAACATGGGTCCAGTGT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDSLPLGSSGLRCSALGLGCMGMSEFYGPSDDARSLATLEAAVEQGITLFDTADMYGAGHNETLLGGFLKGRRDKVVLAT
KFAIVRPTAAYARTIDNSPAYVRSACEASLRRLGIDTIDLYYVHRRNPQTPLEDTLGALAELKAEGKIRAVGLSEVSAQT
LRAAHAILPIAAVQSEYSLWTRDAEAEVLAACAELGITFVAYSPLGRAALTGAITPTTLVEGDFRRAMPRFGAEAWAVNR
PLVEALGDFASARGATPAQVALAWLLGRPQPLVPIFGTRSPERLRENIGAAALRLSADDRAILDALFPPGIAQGMRYTEE
GMKNLDV

Sequences:

>Translated_327_residues
MDSLPLGSSGLRCSALGLGCMGMSEFYGPSDDARSLATLEAAVEQGITLFDTADMYGAGHNETLLGGFLKGRRDKVVLAT
KFAIVRPTAAYARTIDNSPAYVRSACEASLRRLGIDTIDLYYVHRRNPQTPLEDTLGALAELKAEGKIRAVGLSEVSAQT
LRAAHAILPIAAVQSEYSLWTRDAEAEVLAACAELGITFVAYSPLGRAALTGAITPTTLVEGDFRRAMPRFGAEAWAVNR
PLVEALGDFASARGATPAQVALAWLLGRPQPLVPIFGTRSPERLRENIGAAALRLSADDRAILDALFPPGIAQGMRYTEE
GMKNLDV
>Mature_327_residues
MDSLPLGSSGLRCSALGLGCMGMSEFYGPSDDARSLATLEAAVEQGITLFDTADMYGAGHNETLLGGFLKGRRDKVVLAT
KFAIVRPTAAYARTIDNSPAYVRSACEASLRRLGIDTIDLYYVHRRNPQTPLEDTLGALAELKAEGKIRAVGLSEVSAQT
LRAAHAILPIAAVQSEYSLWTRDAEAEVLAACAELGITFVAYSPLGRAALTGAITPTTLVEGDFRRAMPRFGAEAWAVNR
PLVEALGDFASARGATPAQVALAWLLGRPQPLVPIFGTRSPERLRENIGAAALRLSADDRAILDALFPPGIAQGMRYTEE
GMKNLDV

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=27.355623100304, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI4504825, Length=329, Percent_Identity=27.355623100304, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI27436966, Length=300, Percent_Identity=28, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI27436964, Length=305, Percent_Identity=27.8688524590164, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI27436962, Length=300, Percent_Identity=28, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI223718702, Length=296, Percent_Identity=33.1081081081081, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI27436971, Length=306, Percent_Identity=28.4313725490196, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI41327764, Length=283, Percent_Identity=31.4487632508834, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI41152114, Length=294, Percent_Identity=29.2517006802721, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI223718708, Length=133, Percent_Identity=39.8496240601504, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=337, Percent_Identity=33.2344213649852, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=33.6477987421384, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789199, Length=342, Percent_Identity=32.7485380116959, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1787674, Length=301, Percent_Identity=30.8970099667774, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788081, Length=298, Percent_Identity=30.8724832214765, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=29.6296296296296, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17564128, Length=334, Percent_Identity=26.6467065868263, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI212645785, Length=161, Percent_Identity=31.055900621118, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=325, Percent_Identity=24.6153846153846, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=24.1176470588235, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=301, Percent_Identity=23.9202657807309, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6325384, Length=200, Percent_Identity=30.5, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=329, Percent_Identity=24.0121580547112, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=252, Percent_Identity=24.2063492063492, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24646155, Length=316, Percent_Identity=25.6329113924051, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640980, Length=326, Percent_Identity=26.0736196319018, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45549126, Length=326, Percent_Identity=26.0736196319018, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646159, Length=168, Percent_Identity=31.547619047619, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34850; Mature: 34850

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLPLGSSGLRCSALGLGCMGMSEFYGPSDDARSLATLEAAVEQGITLFDTADMYGAGH
CCCCCCCCCCCEEHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCCCC
NETLLGGFLKGRRDKVVLATKFAIVRPTAAYARTIDNSPAYVRSACEASLRRLGIDTIDL
CCHHHHHHHCCCCCEEEEEEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEE
YYVHRRNPQTPLEDTLGALAELKAEGKIRAVGLSEVSAQTLRAAHAILPIAAVQSEYSLW
EEEECCCCCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRDAEAEVLAACAELGITFVAYSPLGRAALTGAITPTTLVEGDFRRAMPRFGAEAWAVNR
CCCCHHHHHHHHHHHCEEEEEECCCCHHHHHCCCCCHHHCCCHHHHHHHHCCCHHHHCCC
PLVEALGDFASARGATPAQVALAWLLGRPQPLVPIFGTRSPERLRENIGAAALRLSADDR
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHCCCCEEEEECCCCH
AILDALFPPGIAQGMRYTEEGMKNLDV
HHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSLPLGSSGLRCSALGLGCMGMSEFYGPSDDARSLATLEAAVEQGITLFDTADMYGAGH
CCCCCCCCCCCEEHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCEEEECHHHCCCCC
NETLLGGFLKGRRDKVVLATKFAIVRPTAAYARTIDNSPAYVRSACEASLRRLGIDTIDL
CCHHHHHHHCCCCCEEEEEEEEEEECCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEE
YYVHRRNPQTPLEDTLGALAELKAEGKIRAVGLSEVSAQTLRAAHAILPIAAVQSEYSLW
EEEECCCCCCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRDAEAEVLAACAELGITFVAYSPLGRAALTGAITPTTLVEGDFRRAMPRFGAEAWAVNR
CCCCHHHHHHHHHHHCEEEEEECCCCHHHHHCCCCCHHHCCCHHHHHHHHCCCHHHHCCC
PLVEALGDFASARGATPAQVALAWLLGRPQPLVPIFGTRSPERLRENIGAAALRLSADDR
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCHHHHHHCCCCEEEEECCCCH
AILDALFPPGIAQGMRYTEEGMKNLDV
HHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]