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The map label for this gene is barA [H]

Identifier: 83592370

GI number: 83592370

Start: 1223706

End: 1225967

Strand: Direct

Name: barA [H]

Synonym: Rru_A1034

Alternate gene names: 83592370

Gene position: 1223706-1225967 (Clockwise)

Preceding gene: 83592364

Following gene: 83592377

Centisome position: 28.11

GC content: 71.49

Gene sequence:

>2262_bases
ATGATTCCCATTTTCAAGGCATGGGCCGCACGCAAGCGCAGTAGCGAGCCGACGGCCGGACAATCGGAGTTCGATCTCGC
CGATCCCTTTGTCGCCTTCTCCGACTCCGACTCCGCTCCACCCTCGGCCGAGCCCCCTTCGTTCGGTCCACCGGCCGCCG
CGCTGCCCCCGGTTTTGACAAAGGGCGATGGCGAGGGGACCGAGGATCCGCTTGTTGCTTGGCGCGCCGAGGAGAGCCCG
CGCCGGCGGACCGATCCTCCGCCCGCCGAGCGGCGCCACGATCCGTTCCTCGGCGGGTCTTTCGGCGGCGCGGGCGATGC
CGTGGCCGAAGAGGTCTCGCGGGCGCTGTCCTGGGACGAGGCGGAGAAGACCGGCGGCCGCGTGGGGGAGGGCGAGGCCG
ATACGCTCGATCCTGTGGACGAGGACGACCTGTATGAGCCGCTGAGCGCGACCCCGCGCGATCCCGACGCGCCGCGCATA
GCCCGCGATCCGCCGTCGCCCCTCGGGGTCGACCCTTTGGAGGCGCCGCGCCGCGAAGCCGAGGATCACCGGGAGTTTTC
GATCCCCCGCTCCGAACCCCTGGCGCCTTTCTTGTTGCCCCCTCTGCCCGAAGACCCCCTGGCGACCAGCCCGTCCCGGG
AGGGCCGGCCGCCGCGACAGGGGGTGGACAAGTCCGACGATCCGGCGGCCATGGCGCCGCTTGCCGCCGCCGCGCCGGTT
GAACGTCCTTCCGGGCAGACGGGCCGCCGTGAGCCTCCCCTTGCGGACATCGCCGACGCGAGCGATTCCGAGCCGCCCGA
GGAGGAGGACCGCGCCGACGAGCAACAGGCGTCGCTCGGGCCGGGCCTTGGCGAGGGGGCGGCCCATGGTATGCCGGCTT
TTCTGGCCGAGCCGGCCAGCGCCCGGTCCGAAGCCCGGACGCGCCTTGATCCGGTGGCCTGCGGACTGCTCGGGCTGATG
GTCTCATTGGGCCCCCTTGGTGTTGCGGCGGGAACGGTCCTGGCGACGGGGAGGATGCCGACGGACCGCTGGACGCTGGC
CGCCGCCGGGGGGCTTGCCGGACTGTTTTTGGTTTGCGCTGGCCTGGCGGCCTGGGGGATCTGGCGCCATCTCGGCGGGC
GGATCACTCGGTTAAGCGCCCAGATCGAGGCGACGGACCAGCGCGGGCGTTTCCTCGGCCGTCAGGCGCGGGCGGCCAAG
GCCTATCTCTCGGGCGTGCTCGACGGGGCGCCGCTGGCCATCGTCACCCTTGACGGCCGGGGCACCATCATTGGCCTCAA
CCCGGCCGCCGAGGCGCTGTTTGGCTATCCGTTGCCCCGCGCCGTCGGCCGGCCGCTGTCCCTGCTGACCGCGGCGGGCG
AAGACGGCGGCCCGCCCTGGCCGGCCCCGACCGGCGAGGAAGAGGGGCCGCGTCGCGTCGAGGGGCGGCGTGCCGATGGC
AGCGTCTTTCCCGCCGAGCTCAGTTTGCGGGCGCTGCGCCGTGAAAACGGCGGCGGGCTGGTGGTGTTGTTCCTGCACGA
TCTTTCGGCCGAAGGGGGGGCAAAGAGCTTGGCGGAAAGCGGCCGCGCCGAGAGCGCCTTCCTTGATGTGCTCGCCAGCG
AACTGGTCGTTCCGGTGGAAGCGATGGCCCTGGCCCTGAGATCGAGCCACCCCGACCTTGAACGGGTCGAGCAGGCGCTA
TCGCTTCTCGGGCAGATCGCCACCGACGTGCGCGGCTTCGCCAATCTGGAAGCCGGCCGCGTCGCCTTGGAATTCGCCCC
CGTCGAGGTGCGCGCCGTCTGCACCCGGGCGCGTGCGGCCGTTCTGGCGCCGGCGGCGGAATTCGGCCTGAAGGTCGGTG
TTTCCGTCGCCCCCGATACGCCCGAAACCATCCTCGGCGACGAAGCCCTGCTTGAAACCGTGCTGACCAATCTTCTTGAT
TGCGCCTTGCAGTTCAACGCGCTCGATCCGGCCGCGCATGCCGCCTTGCCCGGCAGTATCACCTTGTCGGTGCGGCCGCT
GGACAATCCCCCCGGTCGCCTGCGCATCGAAGTGGGATGCCCCGCCAGCGAGGGGGGGCGCGACGGCCTGGATCCGGCCA
GCCGGCGGCGCGGGCCGATCCTGCCCGGCGCCCGGTTGCGGCTGGAACCCGTCGGCAGTCGCGGGCGGACCGGCACCATT
CTGGTGATCACCCGGCGCTTGGCCGAATTGATGGGTGGCCGGGTCGGCATGGAAAGCTTCCCCGGACGCGGCACCGTGTT
GTGGTTCGAACTCGACGATTAG

Upstream 100 bases:

>100_bases
TTGAAAGCGCCCGTCCGGCCAGTCATACCCGGGGGTGACGCGGCGTGCGGATCGCCGGAAGGCGACCCCGGAACGAACGA
CGAGGAAAGAAGGGACGGCG

Downstream 100 bases:

>100_bases
AACAAATCCCCGAGCGCTCGGAACCAGAGCGCGACGACGATTTGCTTCACTGTCAGTATTCTGGAGCGGGTGCGGGGACC
AAGTTTCACGCGTCCCGCCC

Product: multi-sensor Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 753; Mature: 753

Protein sequence:

>753_residues
MIPIFKAWAARKRSSEPTAGQSEFDLADPFVAFSDSDSAPPSAEPPSFGPPAAALPPVLTKGDGEGTEDPLVAWRAEESP
RRRTDPPPAERRHDPFLGGSFGGAGDAVAEEVSRALSWDEAEKTGGRVGEGEADTLDPVDEDDLYEPLSATPRDPDAPRI
ARDPPSPLGVDPLEAPRREAEDHREFSIPRSEPLAPFLLPPLPEDPLATSPSREGRPPRQGVDKSDDPAAMAPLAAAAPV
ERPSGQTGRREPPLADIADASDSEPPEEEDRADEQQASLGPGLGEGAAHGMPAFLAEPASARSEARTRLDPVACGLLGLM
VSLGPLGVAAGTVLATGRMPTDRWTLAAAGGLAGLFLVCAGLAAWGIWRHLGGRITRLSAQIEATDQRGRFLGRQARAAK
AYLSGVLDGAPLAIVTLDGRGTIIGLNPAAEALFGYPLPRAVGRPLSLLTAAGEDGGPPWPAPTGEEEGPRRVEGRRADG
SVFPAELSLRALRRENGGGLVVLFLHDLSAEGGAKSLAESGRAESAFLDVLASELVVPVEAMALALRSSHPDLERVEQAL
SLLGQIATDVRGFANLEAGRVALEFAPVEVRAVCTRARAAVLAPAAEFGLKVGVSVAPDTPETILGDEALLETVLTNLLD
CALQFNALDPAAHAALPGSITLSVRPLDNPPGRLRIEVGCPASEGGRDGLDPASRRRGPILPGARLRLEPVGSRGRTGTI
LVITRRLAELMGGRVGMESFPGRGTVLWFELDD

Sequences:

>Translated_753_residues
MIPIFKAWAARKRSSEPTAGQSEFDLADPFVAFSDSDSAPPSAEPPSFGPPAAALPPVLTKGDGEGTEDPLVAWRAEESP
RRRTDPPPAERRHDPFLGGSFGGAGDAVAEEVSRALSWDEAEKTGGRVGEGEADTLDPVDEDDLYEPLSATPRDPDAPRI
ARDPPSPLGVDPLEAPRREAEDHREFSIPRSEPLAPFLLPPLPEDPLATSPSREGRPPRQGVDKSDDPAAMAPLAAAAPV
ERPSGQTGRREPPLADIADASDSEPPEEEDRADEQQASLGPGLGEGAAHGMPAFLAEPASARSEARTRLDPVACGLLGLM
VSLGPLGVAAGTVLATGRMPTDRWTLAAAGGLAGLFLVCAGLAAWGIWRHLGGRITRLSAQIEATDQRGRFLGRQARAAK
AYLSGVLDGAPLAIVTLDGRGTIIGLNPAAEALFGYPLPRAVGRPLSLLTAAGEDGGPPWPAPTGEEEGPRRVEGRRADG
SVFPAELSLRALRRENGGGLVVLFLHDLSAEGGAKSLAESGRAESAFLDVLASELVVPVEAMALALRSSHPDLERVEQAL
SLLGQIATDVRGFANLEAGRVALEFAPVEVRAVCTRARAAVLAPAAEFGLKVGVSVAPDTPETILGDEALLETVLTNLLD
CALQFNALDPAAHAALPGSITLSVRPLDNPPGRLRIEVGCPASEGGRDGLDPASRRRGPILPGARLRLEPVGSRGRTGTI
LVITRRLAELMGGRVGMESFPGRGTVLWFELDD
>Mature_753_residues
MIPIFKAWAARKRSSEPTAGQSEFDLADPFVAFSDSDSAPPSAEPPSFGPPAAALPPVLTKGDGEGTEDPLVAWRAEESP
RRRTDPPPAERRHDPFLGGSFGGAGDAVAEEVSRALSWDEAEKTGGRVGEGEADTLDPVDEDDLYEPLSATPRDPDAPRI
ARDPPSPLGVDPLEAPRREAEDHREFSIPRSEPLAPFLLPPLPEDPLATSPSREGRPPRQGVDKSDDPAAMAPLAAAAPV
ERPSGQTGRREPPLADIADASDSEPPEEEDRADEQQASLGPGLGEGAAHGMPAFLAEPASARSEARTRLDPVACGLLGLM
VSLGPLGVAAGTVLATGRMPTDRWTLAAAGGLAGLFLVCAGLAAWGIWRHLGGRITRLSAQIEATDQRGRFLGRQARAAK
AYLSGVLDGAPLAIVTLDGRGTIIGLNPAAEALFGYPLPRAVGRPLSLLTAAGEDGGPPWPAPTGEEEGPRRVEGRRADG
SVFPAELSLRALRRENGGGLVVLFLHDLSAEGGAKSLAESGRAESAFLDVLASELVVPVEAMALALRSSHPDLERVEQAL
SLLGQIATDVRGFANLEAGRVALEFAPVEVRAVCTRARAAVLAPAAEFGLKVGVSVAPDTPETILGDEALLETVLTNLLD
CALQFNALDPAAHAALPGSITLSVRPLDNPPGRLRIEVGCPASEGGRDGLDPASRRRGPILPGARLRLEPVGSRGRTGTI
LVITRRLAELMGGRVGMESFPGRGTVLWFELDD

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=261, Percent_Identity=25.6704980842912, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78740; Mature: 78740

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPIFKAWAARKRSSEPTAGQSEFDLADPFVAFSDSDSAPPSAEPPSFGPPAAALPPVLT
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEE
KGDGEGTEDPLVAWRAEESPRRRTDPPPAERRHDPFLGGSFGGAGDAVAEEVSRALSWDE
CCCCCCCCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCH
AEKTGGRVGEGEADTLDPVDEDDLYEPLSATPRDPDAPRIARDPPSPLGVDPLEAPRREA
HHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
EDHREFSIPRSEPLAPFLLPPLPEDPLATSPSREGRPPRQGVDKSDDPAAMAPLAAAAPV
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
ERPSGQTGRREPPLADIADASDSEPPEEEDRADEQQASLGPGLGEGAAHGMPAFLAEPAS
CCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHH
ARSEARTRLDPVACGLLGLMVSLGPLGVAAGTVLATGRMPTDRWTLAAAGGLAGLFLVCA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHHHHH
GLAAWGIWRHLGGRITRLSAQIEATDQRGRFLGRQARAAKAYLSGVLDGAPLAIVTLDGR
HHHHHHHHHHHCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GTIIGLNPAAEALFGYPLPRAVGRPLSLLTAAGEDGGPPWPAPTGEEEGPRRVEGRRADG
EEEEECCHHHHHHHCCCCHHHHCCCCEEHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SVFPAELSLRALRRENGGGLVVLFLHDLSAEGGAKSLAESGRAESAFLDVLASELVVPVE
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
AMALALRSSHPDLERVEQALSLLGQIATDVRGFANLEAGRVALEFAPVEVRAVCTRARAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHH
VLAPAAEFGLKVGVSVAPDTPETILGDEALLETVLTNLLDCALQFNALDPAAHAALPGSI
HHCCHHHHCEEECCEECCCCCHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEE
TLSVRPLDNPPGRLRIEVGCPASEGGRDGLDPASRRRGPILPGARLRLEPVGSRGRTGTI
EEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCEE
LVITRRLAELMGGRVGMESFPGRGTVLWFELDD
EEHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MIPIFKAWAARKRSSEPTAGQSEFDLADPFVAFSDSDSAPPSAEPPSFGPPAAALPPVLT
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEE
KGDGEGTEDPLVAWRAEESPRRRTDPPPAERRHDPFLGGSFGGAGDAVAEEVSRALSWDE
CCCCCCCCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCH
AEKTGGRVGEGEADTLDPVDEDDLYEPLSATPRDPDAPRIARDPPSPLGVDPLEAPRREA
HHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
EDHREFSIPRSEPLAPFLLPPLPEDPLATSPSREGRPPRQGVDKSDDPAAMAPLAAAAPV
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
ERPSGQTGRREPPLADIADASDSEPPEEEDRADEQQASLGPGLGEGAAHGMPAFLAEPAS
CCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCHH
ARSEARTRLDPVACGLLGLMVSLGPLGVAAGTVLATGRMPTDRWTLAAAGGLAGLFLVCA
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHHHHH
GLAAWGIWRHLGGRITRLSAQIEATDQRGRFLGRQARAAKAYLSGVLDGAPLAIVTLDGR
HHHHHHHHHHHCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
GTIIGLNPAAEALFGYPLPRAVGRPLSLLTAAGEDGGPPWPAPTGEEEGPRRVEGRRADG
EEEEECCHHHHHHHCCCCHHHHCCCCEEHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SVFPAELSLRALRRENGGGLVVLFLHDLSAEGGAKSLAESGRAESAFLDVLASELVVPVE
CCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHH
AMALALRSSHPDLERVEQALSLLGQIATDVRGFANLEAGRVALEFAPVEVRAVCTRARAA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHH
VLAPAAEFGLKVGVSVAPDTPETILGDEALLETVLTNLLDCALQFNALDPAAHAALPGSI
HHCCHHHHCEEECCEECCCCCHHHHCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEE
TLSVRPLDNPPGRLRIEVGCPASEGGRDGLDPASRRRGPILPGARLRLEPVGSRGRTGTI
EEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEECCCCCCCCEE
LVITRRLAELMGGRVGMESFPGRGTVLWFELDD
EEHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]