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The map label for this gene is murB

Identifier: 83592284

GI number: 83592284

Start: 1131189

End: 1132148

Strand: Reverse

Name: murB

Synonym: Rru_A0948

Alternate gene names: 83592284

Gene position: 1132148-1131189 (Counterclockwise)

Preceding gene: 83592285

Following gene: 83592283

Centisome position: 26.01

GC content: 71.88

Gene sequence:

>960_bases
ATGATCGCCCTGCGCGCGCCAACCCCGCTGATCGACCGACTGCCCGCCGTGCGCGGACGGCTGAGCGCCGATGTCGCCCT
CGCCCCCGTCACCTGGTTTCGCGTCGGCGGTCCGGCCGAGGCGATGTTCAAGCCGGCCGACGCCCAGGATCTGGCCGATT
TCCTGGCCGGCCGCCCCCGCGATGTCGCGGTGCGAGTGATCGGCGTCGCCTCGAACCTGTTGGTGCGCGACGGCGGGGTG
CCGGGCGTGGTCATCCGCCTGGGCCGGGCCTTCACCGGGGTCGAGGTCGTCGGCGAAACCCTGGTCTGCGGCGCCTCGGC
CCTCGACGCCACGGTCGCCAAGGTCGCCGAGGCCGCCGGTCTGGCCGGGCTGGAATTCCTCTCGGGGATTCCGGGAACCC
TGGGCGGGGCCCTGCGCATGAACGCCGGCGCCCACTTGCGCGAGATGGCCGATATCGTCGTTTTGGCCACCGCCGTCGAT
GGCCTTGGCCAGAGCCACACCCTGACCCCGGCCCAGATGGGATTTTCCTATCGCGCCTGCGCCCTTCCCGAGGACTGGAT
CTTCACCGGCTGCGTCCTGGCCGGCCGGCCCGATGAGCGGGGCGCCATCGCCGCCCGCATGGAGGCCCTGCGCCAAGCCC
GCGAGGCCAGCCAGCCGCTGCGGGCGCGCACCGGCGGATCGACCTTCGCCAATCCCGACCCCGACTTGTCGGGGGGACGG
CGGGCCTGGGAGTTGATCGACGCCGCCGGTTGCCGGGGCCTGCGGCTGGGCGGCGCCCAGGTCAGCGAAAAGCACTGCAA
TTTCCTGATCAACACCGGCGAGGCGACGGCGGCGGATCTGGAAGCCCTGGGCGAGACCGTGCGGCGCCGGGTCATGGACA
CCTCGGGGGTCGCCCTGCGGTGGGAAATCAAGCGAATCGGGATCGGTCTTGACGGCCTTTCCGCGGGAGAAAACGGATGA

Upstream 100 bases:

>100_bases
TGGGGGCGGGCAGCATTTCCACCTGGGCCAACGCCCTGCCCAAGCAGCTTGAGGCGGTTCAGGGCAGGCGCCGTCAGACC
ACCCTGGCCGGGGGGGCGCC

Downstream 100 bases:

>100_bases
GTAAGCGCGTGACCGTTCTGATGGGCGGCTTTTCGACCGAGCGTGCGGTGTCGCTAAACAGCGGCGCGGCGGCCGGCGAG
GCCTTGCGTCAGGCCGGCTA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MIALRAPTPLIDRLPAVRGRLSADVALAPVTWFRVGGPAEAMFKPADAQDLADFLAGRPRDVAVRVIGVASNLLVRDGGV
PGVVIRLGRAFTGVEVVGETLVCGASALDATVAKVAEAAGLAGLEFLSGIPGTLGGALRMNAGAHLREMADIVVLATAVD
GLGQSHTLTPAQMGFSYRACALPEDWIFTGCVLAGRPDERGAIAARMEALRQAREASQPLRARTGGSTFANPDPDLSGGR
RAWELIDAAGCRGLRLGGAQVSEKHCNFLINTGEATAADLEALGETVRRRVMDTSGVALRWEIKRIGIGLDGLSAGENG

Sequences:

>Translated_319_residues
MIALRAPTPLIDRLPAVRGRLSADVALAPVTWFRVGGPAEAMFKPADAQDLADFLAGRPRDVAVRVIGVASNLLVRDGGV
PGVVIRLGRAFTGVEVVGETLVCGASALDATVAKVAEAAGLAGLEFLSGIPGTLGGALRMNAGAHLREMADIVVLATAVD
GLGQSHTLTPAQMGFSYRACALPEDWIFTGCVLAGRPDERGAIAARMEALRQAREASQPLRARTGGSTFANPDPDLSGGR
RAWELIDAAGCRGLRLGGAQVSEKHCNFLINTGEATAADLEALGETVRRRVMDTSGVALRWEIKRIGIGLDGLSAGENG
>Mature_319_residues
MIALRAPTPLIDRLPAVRGRLSADVALAPVTWFRVGGPAEAMFKPADAQDLADFLAGRPRDVAVRVIGVASNLLVRDGGV
PGVVIRLGRAFTGVEVVGETLVCGASALDATVAKVAEAAGLAGLEFLSGIPGTLGGALRMNAGAHLREMADIVVLATAVD
GLGQSHTLTPAQMGFSYRACALPEDWIFTGCVLAGRPDERGAIAARMEALRQAREASQPLRARTGGSTFANPDPDLSGGR
RAWELIDAAGCRGLRLGGAQVSEKHCNFLINTGEATAADLEALGETVRRRVMDTSGVALRWEIKRIGIGLDGLSAGENG

Specific function: Cell wall formation

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURB_RHORT (Q2RVU6)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_426036.1
- ProteinModelPortal:   Q2RVU6
- SMR:   Q2RVU6
- STRING:   Q2RVU6
- GeneID:   3834405
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A0948
- NMPDR:   fig|1085.1.peg.3424
- eggNOG:   COG0812
- HOGENOM:   HBG686573
- OMA:   SKKHAGF
- ProtClustDB:   PRK13905
- BioCyc:   RRUB269796:RRU_A0948-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00037
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094
- Gene3D:   G3DSA:3.30.465.10
- Gene3D:   G3DSA:3.30.43.10
- Gene3D:   G3DSA:3.90.78.10
- PANTHER:   PTHR21071
- TIGRFAMs:   TIGR00179

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C; SSF56176 FAD-binding_2; SSF56194 MurB_C

EC number: =1.1.1.158

Molecular weight: Translated: 33107; Mature: 33107

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS51387 FAD_PCMH

Important sites: ACT_SITE 178-178 ACT_SITE 227-227 ACT_SITE 302-302

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALRAPTPLIDRLPAVRGRLSADVALAPVTWFRVGGPAEAMFKPADAQDLADFLAGRPR
CEEECCCCCHHHHHHHHHCCCCCCEEEECEEEEECCCCHHHHCCCCCHHHHHHHHCCCCC
DVAVRVIGVASNLLVRDGGVPGVVIRLGRAFTGVEVVGETLVCGASALDATVAKVAEAAG
CEEEEEEEECCCEEEECCCCCEEEHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
LAGLEFLSGIPGTLGGALRMNAGAHLREMADIVVLATAVDGLGQSHTLTPAQMGFSYRAC
CHHHHHHCCCCCHHCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEC
ALPEDWIFTGCVLAGRPDERGAIAARMEALRQAREASQPLRARTGGSTFANPDPDLSGGR
CCCCCHHHHCEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCH
RAWELIDAAGCRGLRLGGAQVSEKHCNFLINTGEATAADLEALGETVRRRVMDTSGVALR
HHHHHHHHCCCCCEEECCCHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEE
WEIKRIGIGLDGLSAGENG
EEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MIALRAPTPLIDRLPAVRGRLSADVALAPVTWFRVGGPAEAMFKPADAQDLADFLAGRPR
CEEECCCCCHHHHHHHHHCCCCCCEEEECEEEEECCCCHHHHCCCCCHHHHHHHHCCCCC
DVAVRVIGVASNLLVRDGGVPGVVIRLGRAFTGVEVVGETLVCGASALDATVAKVAEAAG
CEEEEEEEECCCEEEECCCCCEEEHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
LAGLEFLSGIPGTLGGALRMNAGAHLREMADIVVLATAVDGLGQSHTLTPAQMGFSYRAC
CHHHHHHCCCCCHHCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEC
ALPEDWIFTGCVLAGRPDERGAIAARMEALRQAREASQPLRARTGGSTFANPDPDLSGGR
CCCCCHHHHCEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCH
RAWELIDAAGCRGLRLGGAQVSEKHCNFLINTGEATAADLEALGETVRRRVMDTSGVALR
HHHHHHHHCCCCCEEECCCHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEE
WEIKRIGIGLDGLSAGENG
EEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA