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The map label for this gene is ampG [H]

Identifier: 83592184

GI number: 83592184

Start: 1010237

End: 1011478

Strand: Direct

Name: ampG [H]

Synonym: Rru_A0848

Alternate gene names: 83592184

Gene position: 1010237-1011478 (Clockwise)

Preceding gene: 83592183

Following gene: 83592185

Centisome position: 23.21

GC content: 67.55

Gene sequence:

>1242_bases
ATGCTTGAACTGCTTCGCCATCGCCGCTTGGTCGTCACCCTGGCCTTGCTGTACGTGTCCCAGGGCCTTCCCATCGGGAT
CGCCATGGACGCCCTGCCGACCCTGTTGCGGCATGATGGCGCGTCCTTGCGGGCGCTGGCCTTCCTGCCTTTGGTGGGTC
TGCCCTGGGTGGTCAAGTTCCTCTGGGCGTCCTGGGTGGATAACCATTGGACCGCGCGCCTGGGGCGACGGCGGAGCTGG
ATCCTGCCGATGCAGGGCGTGGTTCTGGCCTGCCTGCTTGGCCTCGCGCTGGTTGGCGTCGGCGTGGCCTCGGCCGGCTG
GGTGGTCGGCCTGATGGCGGTAGCCTCCCTGGCCAGCGCCACCCAGGATATCGCCACCGACGGCATGGCCGCCGAGCATT
TCGCGGGGGATCTGCTGACCAAGGTCAACGCGATTCAAGTCGCGGGGGTGATGATCGGCTTCTTCGCCGGCGGCGCCGGA
AACCTGATCCTGGTGGGGCATTTCGGGCAGACCATCGCTTTTCTGACCCTGTTTTGCGTTCCTTTGGCGAGCTTGGTGTT
CGTCGGTCTCCTGCCCCCGGACGCCCCGAGGGGGCGCGCGGACGCGGCGCCCGCGGGAGCCAGCTTGTGGGGATTCATTC
GCCGGCCGATGGCCCCCTCGCTTCTGCTGTTGGCCTTGCTGTCGGCGATGACCGCGGTGTCGGGCTTCGGTTTGTCCAAG
CTGTTTCTCACCGACGCCGGCTGGGCGCTTGAGGACATCGGCCGGCTCGGCATGAGCGGAGGGATGATCACCATCCTCCT
CGGCTGTGGAGGTGGCGTCTGGCTGGTGAAACGGATCGGGTTGTGGCGGGGATTCGGTGTCGGCGTCTTCTTCGCCGGGG
TGTCGGGATGTCTCTGGTCTCTTCAGGCGGTCCAATGGCTGAGCGTGACCGAGGGCGTGGTTTGGGTGTGTATCGTGCTC
GGCTCCCTGTCCACCGGCATCACTTCGGTGGCGATCCTGACGGAGGCGATGCGCCTCGCCGGTCAGGGCGACCAGGCGGG
GACCGACATCACCGCCGTTCAGAGCACCCGCGATCTGGGGGAACTGCTGGCCTCCTCCTCCCTGGTCGCCGTGACCGCGC
GGCTCGGCTACGGCGGCGCTTTTCTTGGGGGCTGCCTGCTGGCGATTCTGGCCTTGACCGTCGCCCTGCGTCTGAGGCGA
CGGGAACGGCGGGCCACCATGGCGACCGCCGAGGAGTTCTAG

Upstream 100 bases:

>100_bases
ACGCTCTTGCTCTGCGGCGCGCTGTTTTGCCGCCTGTCCTGGGGTTTGGCCCGGTCCTCCGCCCCCCATCCTCCGCTTCC
CGGTCGCATTGGAGACCAGA

Downstream 100 bases:

>100_bases
CAGGCTGCCGGCTGAGTGGTTCTGCGGCTCGTCGCCCCCTTTACGCGGGCGACATGCTAGAAAGCCGGGGTGTCGGCTTG
GGGACGTGCGTTGGCTCGAT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MLELLRHRRLVVTLALLYVSQGLPIGIAMDALPTLLRHDGASLRALAFLPLVGLPWVVKFLWASWVDNHWTARLGRRRSW
ILPMQGVVLACLLGLALVGVGVASAGWVVGLMAVASLASATQDIATDGMAAEHFAGDLLTKVNAIQVAGVMIGFFAGGAG
NLILVGHFGQTIAFLTLFCVPLASLVFVGLLPPDAPRGRADAAPAGASLWGFIRRPMAPSLLLLALLSAMTAVSGFGLSK
LFLTDAGWALEDIGRLGMSGGMITILLGCGGGVWLVKRIGLWRGFGVGVFFAGVSGCLWSLQAVQWLSVTEGVVWVCIVL
GSLSTGITSVAILTEAMRLAGQGDQAGTDITAVQSTRDLGELLASSSLVAVTARLGYGGAFLGGCLLAILALTVALRLRR
RERRATMATAEEF

Sequences:

>Translated_413_residues
MLELLRHRRLVVTLALLYVSQGLPIGIAMDALPTLLRHDGASLRALAFLPLVGLPWVVKFLWASWVDNHWTARLGRRRSW
ILPMQGVVLACLLGLALVGVGVASAGWVVGLMAVASLASATQDIATDGMAAEHFAGDLLTKVNAIQVAGVMIGFFAGGAG
NLILVGHFGQTIAFLTLFCVPLASLVFVGLLPPDAPRGRADAAPAGASLWGFIRRPMAPSLLLLALLSAMTAVSGFGLSK
LFLTDAGWALEDIGRLGMSGGMITILLGCGGGVWLVKRIGLWRGFGVGVFFAGVSGCLWSLQAVQWLSVTEGVVWVCIVL
GSLSTGITSVAILTEAMRLAGQGDQAGTDITAVQSTRDLGELLASSSLVAVTARLGYGGAFLGGCLLAILALTVALRLRR
RERRATMATAEEF
>Mature_413_residues
MLELLRHRRLVVTLALLYVSQGLPIGIAMDALPTLLRHDGASLRALAFLPLVGLPWVVKFLWASWVDNHWTARLGRRRSW
ILPMQGVVLACLLGLALVGVGVASAGWVVGLMAVASLASATQDIATDGMAAEHFAGDLLTKVNAIQVAGVMIGFFAGGAG
NLILVGHFGQTIAFLTLFCVPLASLVFVGLLPPDAPRGRADAAPAGASLWGFIRRPMAPSLLLLALLSAMTAVSGFGLSK
LFLTDAGWALEDIGRLGMSGGMITILLGCGGGVWLVKRIGLWRGFGVGVFFAGVSGCLWSLQAVQWLSVTEGVVWVCIVL
GSLSTGITSVAILTEAMRLAGQGDQAGTDITAVQSTRDLGELLASSSLVAVTARLGYGGAFLGGCLLAILALTVALRLRR
RERRATMATAEEF

Specific function: Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786636, Length=287, Percent_Identity=25.4355400696864, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319697, Length=164, Percent_Identity=32.3170731707317, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24665528, Length=130, Percent_Identity=39.2307692307692, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665524, Length=130, Percent_Identity=39.2307692307692, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004752
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43196; Mature: 43196

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLELLRHRRLVVTLALLYVSQGLPIGIAMDALPTLLRHDGASLRALAFLPLVGLPWVVKF
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LWASWVDNHWTARLGRRRSWILPMQGVVLACLLGLALVGVGVASAGWVVGLMAVASLASA
HHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQDIATDGMAAEHFAGDLLTKVNAIQVAGVMIGFFAGGAGNLILVGHFGQTIAFLTLFCV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHH
PLASLVFVGLLPPDAPRGRADAAPAGASLWGFIRRPMAPSLLLLALLSAMTAVSGFGLSK
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHH
LFLTDAGWALEDIGRLGMSGGMITILLGCGGGVWLVKRIGLWRGFGVGVFFAGVSGCLWS
HHHHCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LQAVQWLSVTEGVVWVCIVLGSLSTGITSVAILTEAMRLAGQGDQAGTDITAVQSTRDLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ELLASSSLVAVTARLGYGGAFLGGCLLAILALTVALRLRRRERRATMATAEEF
HHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLELLRHRRLVVTLALLYVSQGLPIGIAMDALPTLLRHDGASLRALAFLPLVGLPWVVKF
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LWASWVDNHWTARLGRRRSWILPMQGVVLACLLGLALVGVGVASAGWVVGLMAVASLASA
HHHHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQDIATDGMAAEHFAGDLLTKVNAIQVAGVMIGFFAGGAGNLILVGHFGQTIAFLTLFCV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHH
PLASLVFVGLLPPDAPRGRADAAPAGASLWGFIRRPMAPSLLLLALLSAMTAVSGFGLSK
HHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHH
LFLTDAGWALEDIGRLGMSGGMITILLGCGGGVWLVKRIGLWRGFGVGVFFAGVSGCLWS
HHHHCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LQAVQWLSVTEGVVWVCIVLGSLSTGITSVAILTEAMRLAGQGDQAGTDITAVQSTRDLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ELLASSSLVAVTARLGYGGAFLGGCLLAILALTVALRLRRRERRATMATAEEF
HHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]