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The map label for this gene is yhdN [H]

Identifier: 83592098

GI number: 83592098

Start: 891666

End: 892574

Strand: Direct

Name: yhdN [H]

Synonym: Rru_A0759

Alternate gene names: 83592098

Gene position: 891666-892574 (Clockwise)

Preceding gene: 83592097

Following gene: 83592099

Centisome position: 20.48

GC content: 67.66

Gene sequence:

>909_bases
ATGCGAACGAGGCGCCTGGGAAAGACCGCGCTGCGCGCGTCGCAGGTTGGTCTGGGCACATGGCCGCTGGCGGGCAATGC
CGGCTTGGCGGGCTATGGCGCCGTTGATCCCGAGCGGGCCGAAGCCACCGTTCGCGCCGCCCTGGCGGCGGGCATCACGC
TTTTCGATACAGCGGGCATCTATGGCGATGGGTTCGCCGAAAGTCTGTTGGGGCGGCTGCTTCCCGGCGGCGAGGGGGGG
GCGGTCGTGTGCACCAAGGGGGGCTTCTCGCATTTCGCCCAGGGCAGGGCGCCCGACCGCCGCGCTTTCAAGGCCGAGGT
GGCGGCGAGTCGTGATCGCCTGCGCCGCGAGGTGATCGACATCTATCTGTTGCATAACCCGCCGCCCGTCCTGATCGGCC
TGCCCGACGTTTACCGCCCGCTGCAAGACCTGCGCGATCATGGGTGGATCGGCCATATCGGCGTTTCCGTCGCCCGCGCC
ATCGATGGCTGGCTGGCCCTCGACCGCCCCGAGGTCGAAGTGGTGCAACTACCCTTTAACCTGCTTAATACCCAGGCCGA
TCAAGGGCTTCTAAGCCGGGCCGCCGATCTGGGCAAGGCGGTTCTGGCCCGTGAGGTTCTGGCGAACGGCTGGTTGTCGG
GACGCTATGGCCCCGCATCGACCTTCGCCGCCGGGGACTTCCGCCAGCATCTGCCGGCCGAGGTCAAGGCGGCCATCGCC
GGCGATCGCGCCGCCCTTGAGCCCTATCGCCGCCCGGGCGAAAGCTGGGTGGATTTTTCGCTGCGCTTCGTTCTCGACCG
TCCAGAAATTTCCAGCGCCATCGTCGGGGCGAGACATCCCCAGCAGATCGAGGCGCTTTCAAAAGCCGGTACCCTGTCCC
CCTCGCCTTCGTGGCACCCGGCGGACTGA

Upstream 100 bases:

>100_bases
GCAATTCCCTTTCAAGGGGAATTGCGCTAGCGTTCTCCTTGTAAGGGTGTTTTGGCGTGAATGACGGTCGGAGTGGGGTT
CTGAACAAGGGGGGACTCGG

Downstream 100 bases:

>100_bases
AGGGCAGGCTGTTTGCATCCCTGATCTTTGGCAATGGAGGACACCATGGCGGACCCAAGAAATCCTACTGGCCCCTTCGC
TTCAAGCCCACGCGGCCCCT

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRTRRLGKTALRASQVGLGTWPLAGNAGLAGYGAVDPERAEATVRAALAAGITLFDTAGIYGDGFAESLLGRLLPGGEGG
AVVCTKGGFSHFAQGRAPDRRAFKAEVAASRDRLRREVIDIYLLHNPPPVLIGLPDVYRPLQDLRDHGWIGHIGVSVARA
IDGWLALDRPEVEVVQLPFNLLNTQADQGLLSRAADLGKAVLAREVLANGWLSGRYGPASTFAAGDFRQHLPAEVKAAIA
GDRAALEPYRRPGESWVDFSLRFVLDRPEISSAIVGARHPQQIEALSKAGTLSPSPSWHPAD

Sequences:

>Translated_302_residues
MRTRRLGKTALRASQVGLGTWPLAGNAGLAGYGAVDPERAEATVRAALAAGITLFDTAGIYGDGFAESLLGRLLPGGEGG
AVVCTKGGFSHFAQGRAPDRRAFKAEVAASRDRLRREVIDIYLLHNPPPVLIGLPDVYRPLQDLRDHGWIGHIGVSVARA
IDGWLALDRPEVEVVQLPFNLLNTQADQGLLSRAADLGKAVLAREVLANGWLSGRYGPASTFAAGDFRQHLPAEVKAAIA
GDRAALEPYRRPGESWVDFSLRFVLDRPEISSAIVGARHPQQIEALSKAGTLSPSPSWHPAD
>Mature_302_residues
MRTRRLGKTALRASQVGLGTWPLAGNAGLAGYGAVDPERAEATVRAALAAGITLFDTAGIYGDGFAESLLGRLLPGGEGG
AVVCTKGGFSHFAQGRAPDRRAFKAEVAASRDRLRREVIDIYLLHNPPPVLIGLPDVYRPLQDLRDHGWIGHIGVSVARA
IDGWLALDRPEVEVVQLPFNLLNTQADQGLLSRAADLGKAVLAREVLANGWLSGRYGPASTFAAGDFRQHLPAEVKAAIA
GDRAALEPYRRPGESWVDFSLRFVLDRPEISSAIVGARHPQQIEALSKAGTLSPSPSWHPAD

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=310, Percent_Identity=26.4516129032258, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27436962, Length=311, Percent_Identity=26.3665594855305, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27436966, Length=310, Percent_Identity=26.4516129032258, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI27436969, Length=235, Percent_Identity=28.5106382978723, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4504825, Length=232, Percent_Identity=28.448275862069, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788070, Length=310, Percent_Identity=27.0967741935484, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640980, Length=159, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45549126, Length=159, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 32241; Mature: 32241

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRRLGKTALRASQVGLGTWPLAGNAGLAGYGAVDPERAEATVRAALAAGITLFDTAGI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCC
YGDGFAESLLGRLLPGGEGGAVVCTKGGFSHFAQGRAPDRRAFKAEVAASRDRLRREVID
CCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHE
IYLLHNPPPVLIGLPDVYRPLQDLRDHGWIGHIGVSVARAIDGWLALDRPEVEVVQLPFN
EEEECCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECHH
LLNTQADQGLLSRAADLGKAVLAREVLANGWLSGRYGPASTFAAGDFRQHLPAEVKAAIA
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHC
GDRAALEPYRRPGESWVDFSLRFVLDRPEISSAIVGARHPQQIEALSKAGTLSPSPSWHP
CCHHHHHHHHCCCCHHHCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
AD
CC
>Mature Secondary Structure
MRTRRLGKTALRASQVGLGTWPLAGNAGLAGYGAVDPERAEATVRAALAAGITLFDTAGI
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCC
YGDGFAESLLGRLLPGGEGGAVVCTKGGFSHFAQGRAPDRRAFKAEVAASRDRLRREVID
CCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHE
IYLLHNPPPVLIGLPDVYRPLQDLRDHGWIGHIGVSVARAIDGWLALDRPEVEVVQLPFN
EEEECCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECHH
LLNTQADQGLLSRAADLGKAVLAREVLANGWLSGRYGPASTFAAGDFRQHLPAEVKAAIA
HHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHC
GDRAALEPYRRPGESWVDFSLRFVLDRPEISSAIVGARHPQQIEALSKAGTLSPSPSWHP
CCHHHHHHHHCCCCHHHCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
AD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]