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The map label for this gene is clpB [H]

Identifier: 83592092

GI number: 83592092

Start: 882809

End: 885421

Strand: Direct

Name: clpB [H]

Synonym: Rru_A0753

Alternate gene names: 83592092

Gene position: 882809-885421 (Clockwise)

Preceding gene: 83592091

Following gene: 83592093

Centisome position: 20.28

GC content: 64.6

Gene sequence:

>2613_bases
ATGGATCCCGAAAAACTGACGGATCGGTCGAAGGGCTTTCTGCAGGCGGCTCAGACCATCGCCCTGCGCGAAACCCACCA
GCAGGTGACGCCCGAGCATCTGCTCAAGGCCCTGCTTGATGATAAAGAAGGATTGGCGGCCAATTTGATTCGCGCCGCTG
GCGGTGACCCGCTGCGCGCCCAGGAGGCGGTCAACCGCGAAGTCGACAAACTGCCCAAGGTGCAAGGCGCCCAGCAGATG
TATTGGGCCCAGTCGCTGGCCCGGGTGATCGATCAGGCGACGCGCATGGCCGAAAAGGCCGGCGATAGCTTCGTGACCGT
GGAGCGCTTGCTGATCGCCCTGGCGATGGCCGCCGAGACCCCGGCCAAGCGCATCCTCGCCGAGGCCGGCGCCACGCCCC
AGGGCCTCAACAAGGCGGTCGAAGACCTGCGCAAGGGCCGCAAGGCCGATAGCGCCGGGGCGGAATCCCAATATGACGCC
CTGAAGAAATACGCCCGCGACCTGACCGAGGCGGCGCGCGAGGGCAAGCTTGACCCGGTGATCGGCCGCGACGAGGAAAT
CCGCCGCACCATCCAGGTGCTCAGCCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGTGTCGGCAAGACGG
CGATCATCGAGGGTCTGGCCCTGCGCATCGTCAATGGCGACGTTCCCGAAAGCCTGCAGAACAAGAAGCTGATGGCCCTT
GACCTTGGCGCCATGGTCGCCGGCGCCAAGTTCCGTGGCGAGTTCGAGGAACGCCTGAAGGCGATGCTGACCGAGGTGTC
GGCGGCCGAGGGCGAGATCATCTTGTTCATCGACGAGATGCACACCCTGATCGGCGCCGGGGCCGGGGAGGGGGCGATGG
ACGCCTCGAACCTGCTCAAGCCGGCCTTGGCGCGCGGCGATCTGCATTGCGTTGGCGCGACCACGCTCAATGAATACCGC
AAGCATGTGGAAAAGGACGCGGCCCTGGCCCGGCGTTTCCAGCCGGTTTTCGTCTCCGAGCCGGGTGTGGCCGATACCAT
TTCGATCCTGCGCGGCATCAAGGAGAAGTACGAGCTGCACCACGGGGTGCGCATCGCCGATAACGCCCTGGTCGCCGCCG
CCACCTTGTCCAACCGCTATATCACCGACCGCTTCCTGCCCGATAAGGCCATCGACCTGATGGACGAGGCGGCAAGCCGC
CTGCGCATGGAGGTCGACAGCAAGCCCGAGGCCCTGGACGAGCTTGATCGCCGCATCATCCAGCTGAAAATCGAGCGCGA
GGCCCTGCGCAAGGAAAAGGACATCGCCTCGGAGGCCCGTCTTAGCGATCTGGAAAAGGAACTGGCCGATCTGGAAAGCC
AGTCGGCGACCCTGACCGAGGACTGGAAGCGCGAAAAGGAAGGTCTGGCCGGATCGACGCGCATCAAGGAGCAATTGGAG
CAGGCGCGCGGTGATCTTGATATCGCCAAACGCCAAGCCAATTGGGCGCGGGCGGGCGAGTTGGAATATGGCGTCATCCC
CGATCTCGAACGCCGTTTGGGCGAGGTCGAATCCGGTGATGGCCTCGCCCATCGCCAGGGTGGCAAGCTGGTCAACGAGG
TGGTGACCGCCGAGACCATCGCTTCGGTGGTGTCGCGCTGGACCGGCATTCCCGTTGACAAGATGCTGGCGGGCGAACGC
GAAAAGCTGCTGGGCATGGAAAAGGTTCTGGCTTCAAGGGTGGTCGGCCAGCGCGAGGCGGTGGTGGCCGTTTCCAACGC
CGTCCGCCGCTCGCGGGCCGGCTTGCAAGATCCCAACCGGCCGATGGGGTCGTTCCTGTTCCTCGGCCCCACCGGCGTGG
GCAAGACCGAACTGACCAAGGCCCTGGCCGCCTTCCTGTTCGACGACGAGCAGGCGATGGTGCGCATCGACATGTCCGAA
TACATGGAAAAGCACGCGGTTTCCCGGCTGATCGGCGCGCCTCCGGGCTATGTCGGCTATGACGAGGGCGGGGCTTTGAC
CGAGGCGGTGCGGCGCCGGCCCTATCAGGTGATCTTGTTTGACGAGGTCGAGAAGGCCCATCCCGATGTGTTCAACGTGC
TTCTGCAGGTGCTTGACGACGGCCGCTTGACCGATGGCCAGGGCCGCACCGTCGATTTCCGCAATACCCTGATCGTGCTG
ACCTCGAACCTGGGGGCCGATATCCTGGCCAACCAGCCCGAGGGCGATGATTCAGGCGCGGTGCGCGGCGCGGTGATGGA
GATGGTGCGCGCCGCCTTCCGCCCCGAGTTCCTGAACCGCCTTGACGAGATCTTGCTGTTCCATCGCCTGTTCCGCGAGA
ACATGGCCGGGATCGTGTCGATCCAGCTTGGCCGTTTGGCCGACCGGCTGCGCGATCGCAAGATGACCCTTGATCTGGAC
GACGCGGCGCGCGACTGGCTGGCCGAGCGCGGCTATGACCCGGTCTATGGCGCCCGGCCGCTTAAGCGGGTGATCCAGCG
CTCTTTGGAAAATCCGCTGGCCACCCTGGTGCTTGATGGCCGGATCAAGGATGGCGATGTCATCCGCATTACCGTTGAAG
GAGGCAAACTGGTGGTCAATGGCGAAGCGTTGTCTTTGGACACCGCCGCATGA

Upstream 100 bases:

>100_bases
CCCCATATCTACCGTGACCATATGCCTGGAAGGGCGAGGACGCCGCCGTATGTCGGGGCGCCATGCCCGGTCCCCTAGAG
AAGGTGAGGATGGATAGATT

Downstream 100 bases:

>100_bases
ACACGGCGGGTGAAGGCGCCCTGACCGGCGACGGATCAAGCACCGGGGAAACGACGGGGGGCGGGCTGCCGCTCGTCGCC
TTGTCGCAGACCTCGGTGGC

Product: chaperone clpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 870; Mature: 870

Protein sequence:

>870_residues
MDPEKLTDRSKGFLQAAQTIALRETHQQVTPEHLLKALLDDKEGLAANLIRAAGGDPLRAQEAVNREVDKLPKVQGAQQM
YWAQSLARVIDQATRMAEKAGDSFVTVERLLIALAMAAETPAKRILAEAGATPQGLNKAVEDLRKGRKADSAGAESQYDA
LKKYARDLTEAAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIIEGLALRIVNGDVPESLQNKKLMAL
DLGAMVAGAKFRGEFEERLKAMLTEVSAAEGEIILFIDEMHTLIGAGAGEGAMDASNLLKPALARGDLHCVGATTLNEYR
KHVEKDAALARRFQPVFVSEPGVADTISILRGIKEKYELHHGVRIADNALVAAATLSNRYITDRFLPDKAIDLMDEAASR
LRMEVDSKPEALDELDRRIIQLKIEREALRKEKDIASEARLSDLEKELADLESQSATLTEDWKREKEGLAGSTRIKEQLE
QARGDLDIAKRQANWARAGELEYGVIPDLERRLGEVESGDGLAHRQGGKLVNEVVTAETIASVVSRWTGIPVDKMLAGER
EKLLGMEKVLASRVVGQREAVVAVSNAVRRSRAGLQDPNRPMGSFLFLGPTGVGKTELTKALAAFLFDDEQAMVRIDMSE
YMEKHAVSRLIGAPPGYVGYDEGGALTEAVRRRPYQVILFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIVL
TSNLGADILANQPEGDDSGAVRGAVMEMVRAAFRPEFLNRLDEILLFHRLFRENMAGIVSIQLGRLADRLRDRKMTLDLD
DAARDWLAERGYDPVYGARPLKRVIQRSLENPLATLVLDGRIKDGDVIRITVEGGKLVVNGEALSLDTAA

Sequences:

>Translated_870_residues
MDPEKLTDRSKGFLQAAQTIALRETHQQVTPEHLLKALLDDKEGLAANLIRAAGGDPLRAQEAVNREVDKLPKVQGAQQM
YWAQSLARVIDQATRMAEKAGDSFVTVERLLIALAMAAETPAKRILAEAGATPQGLNKAVEDLRKGRKADSAGAESQYDA
LKKYARDLTEAAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIIEGLALRIVNGDVPESLQNKKLMAL
DLGAMVAGAKFRGEFEERLKAMLTEVSAAEGEIILFIDEMHTLIGAGAGEGAMDASNLLKPALARGDLHCVGATTLNEYR
KHVEKDAALARRFQPVFVSEPGVADTISILRGIKEKYELHHGVRIADNALVAAATLSNRYITDRFLPDKAIDLMDEAASR
LRMEVDSKPEALDELDRRIIQLKIEREALRKEKDIASEARLSDLEKELADLESQSATLTEDWKREKEGLAGSTRIKEQLE
QARGDLDIAKRQANWARAGELEYGVIPDLERRLGEVESGDGLAHRQGGKLVNEVVTAETIASVVSRWTGIPVDKMLAGER
EKLLGMEKVLASRVVGQREAVVAVSNAVRRSRAGLQDPNRPMGSFLFLGPTGVGKTELTKALAAFLFDDEQAMVRIDMSE
YMEKHAVSRLIGAPPGYVGYDEGGALTEAVRRRPYQVILFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIVL
TSNLGADILANQPEGDDSGAVRGAVMEMVRAAFRPEFLNRLDEILLFHRLFRENMAGIVSIQLGRLADRLRDRKMTLDLD
DAARDWLAERGYDPVYGARPLKRVIQRSLENPLATLVLDGRIKDGDVIRITVEGGKLVVNGEALSLDTAA
>Mature_870_residues
MDPEKLTDRSKGFLQAAQTIALRETHQQVTPEHLLKALLDDKEGLAANLIRAAGGDPLRAQEAVNREVDKLPKVQGAQQM
YWAQSLARVIDQATRMAEKAGDSFVTVERLLIALAMAAETPAKRILAEAGATPQGLNKAVEDLRKGRKADSAGAESQYDA
LKKYARDLTEAAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIIEGLALRIVNGDVPESLQNKKLMAL
DLGAMVAGAKFRGEFEERLKAMLTEVSAAEGEIILFIDEMHTLIGAGAGEGAMDASNLLKPALARGDLHCVGATTLNEYR
KHVEKDAALARRFQPVFVSEPGVADTISILRGIKEKYELHHGVRIADNALVAAATLSNRYITDRFLPDKAIDLMDEAASR
LRMEVDSKPEALDELDRRIIQLKIEREALRKEKDIASEARLSDLEKELADLESQSATLTEDWKREKEGLAGSTRIKEQLE
QARGDLDIAKRQANWARAGELEYGVIPDLERRLGEVESGDGLAHRQGGKLVNEVVTAETIASVVSRWTGIPVDKMLAGER
EKLLGMEKVLASRVVGQREAVVAVSNAVRRSRAGLQDPNRPMGSFLFLGPTGVGKTELTKALAAFLFDDEQAMVRIDMSE
YMEKHAVSRLIGAPPGYVGYDEGGALTEAVRRRPYQVILFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIVL
TSNLGADILANQPEGDDSGAVRGAVMEMVRAAFRPEFLNRLDEILLFHRLFRENMAGIVSIQLGRLADRLRDRKMTLDLD
DAARDWLAERGYDPVYGARPLKRVIQRSLENPLATLVLDGRIKDGDVIRITVEGGKLVVNGEALSLDTAA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=318, Percent_Identity=36.4779874213836, Blast_Score=209, Evalue=1e-53,
Organism=Escherichia coli, GI1788943, Length=859, Percent_Identity=58.7892898719441, Blast_Score=1002, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=441, Percent_Identity=38.7755102040816, Blast_Score=277, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=705, Percent_Identity=55.886524822695, Blast_Score=801, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=868, Percent_Identity=44.3548387096774, Blast_Score=711, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95559; Mature: 95559

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPEKLTDRSKGFLQAAQTIALRETHQQVTPEHLLKALLDDKEGLAANLIRAAGGDPLRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHH
QEAVNREVDKLPKVQGAQQMYWAQSLARVIDQATRMAEKAGDSFVTVERLLIALAMAAET
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
PAKRILAEAGATPQGLNKAVEDLRKGRKADSAGAESQYDALKKYARDLTEAAREGKLDPV
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIIEGLALRIVNGDVPESLQNKKLMAL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEECCCCCHHHHCCEEEEE
DLGAMVAGAKFRGEFEERLKAMLTEVSAAEGEIILFIDEMHTLIGAGAGEGAMDASNLLK
EHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHHH
PALARGDLHCVGATTLNEYRKHVEKDAALARRFQPVFVSEPGVADTISILRGIKEKYELH
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHH
HGVRIADNALVAAATLSNRYITDRFLPDKAIDLMDEAASRLRMEVDSKPEALDELDRRII
CCCEEECCCEEEHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QLKIEREALRKEKDIASEARLSDLEKELADLESQSATLTEDWKREKEGLAGSTRIKEQLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHH
QARGDLDIAKRQANWARAGELEYGVIPDLERRLGEVESGDGLAHRQGGKLVNEVVTAETI
HHCCCHHHHHHHCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHH
ASVVSRWTGIPVDKMLAGEREKLLGMEKVLASRVVGQREAVVAVSNAVRRSRAGLQDPNR
HHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCC
PMGSFLFLGPTGVGKTELTKALAAFLFDDEQAMVRIDMSEYMEKHAVSRLIGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCC
DEGGALTEAVRRRPYQVILFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIVL
CCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
TSNLGADILANQPEGDDSGAVRGAVMEMVRAAFRPEFLNRLDEILLFHRLFRENMAGIVS
ECCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEH
IQLGRLADRLRDRKMTLDLDDAARDWLAERGYDPVYGARPLKRVIQRSLENPLATLVLDG
HHHHHHHHHHHHCCCEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECC
RIKDGDVIRITVEGGKLVVNGEALSLDTAA
CCCCCCEEEEEEECCEEEECCCEECCCCCC
>Mature Secondary Structure
MDPEKLTDRSKGFLQAAQTIALRETHQQVTPEHLLKALLDDKEGLAANLIRAAGGDPLRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHH
QEAVNREVDKLPKVQGAQQMYWAQSLARVIDQATRMAEKAGDSFVTVERLLIALAMAAET
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
PAKRILAEAGATPQGLNKAVEDLRKGRKADSAGAESQYDALKKYARDLTEAAREGKLDPV
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIIEGLALRIVNGDVPESLQNKKLMAL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHEEECCCCCHHHHCCEEEEE
DLGAMVAGAKFRGEFEERLKAMLTEVSAAEGEIILFIDEMHTLIGAGAGEGAMDASNLLK
EHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHCCCCCCCCCCHHHHHH
PALARGDLHCVGATTLNEYRKHVEKDAALARRFQPVFVSEPGVADTISILRGIKEKYELH
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHH
HGVRIADNALVAAATLSNRYITDRFLPDKAIDLMDEAASRLRMEVDSKPEALDELDRRII
CCCEEECCCEEEHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
QLKIEREALRKEKDIASEARLSDLEKELADLESQSATLTEDWKREKEGLAGSTRIKEQLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHH
QARGDLDIAKRQANWARAGELEYGVIPDLERRLGEVESGDGLAHRQGGKLVNEVVTAETI
HHCCCHHHHHHHCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHH
ASVVSRWTGIPVDKMLAGEREKLLGMEKVLASRVVGQREAVVAVSNAVRRSRAGLQDPNR
HHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCC
PMGSFLFLGPTGVGKTELTKALAAFLFDDEQAMVRIDMSEYMEKHAVSRLIGAPPGYVGY
CCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCC
DEGGALTEAVRRRPYQVILFDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIVL
CCCCHHHHHHHHCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEE
TSNLGADILANQPEGDDSGAVRGAVMEMVRAAFRPEFLNRLDEILLFHRLFRENMAGIVS
ECCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEH
IQLGRLADRLRDRKMTLDLDDAARDWLAERGYDPVYGARPLKRVIQRSLENPLATLVLDG
HHHHHHHHHHHHCCCEECCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEECC
RIKDGDVIRITVEGGKLVVNGEALSLDTAA
CCCCCCEEEEEEECCEEEECCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA