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The map label for this gene is map [H]

Identifier: 83592072

GI number: 83592072

Start: 860118

End: 860933

Strand: Reverse

Name: map [H]

Synonym: Rru_A0733

Alternate gene names: 83592072

Gene position: 860933-860118 (Counterclockwise)

Preceding gene: 83592073

Following gene: 83592071

Centisome position: 19.78

GC content: 61.4

Gene sequence:

>816_bases
ATGAACCAGACTGCCCAACGAGCCCAGCAGGTGACGATTCACGGGCTGGAGGGATTCGAGGGTATGCGCCGTGCCGGACG
TCTCGCCGCCGAAACCCTCGACTTCATCACCCCCTATATCGTGCCCGGCGCGACGACCGAGGATCTCGACCGCCTTTGCG
CCGAGTTCATGGCCGATAATGGCGCGATCAGCGCCACGCTGAACTACCGCGGCTACCCCAAGTCGATCTGCACCTCGATC
AACCATGTGGTCTGTCACGGCATTCCCAGCGAAGACAAGATCCTGCACGACGGCGATATCATGAATATCGACGTCACGCC
GATCCTGGACGGCTGGTATGGCGATTCCAGCCGGATGTATTACGTCGGCGAGCCCAAGGTGAAGGCCAAGCGCTTGGTCG
AAGCTACCTATGAATGCCTGATGCGCGGCATCGCCGTGGTCAAGCCCGGCGCTACCCTGGGCGATATCGGCTATGCGATC
CAAAGCTATGCCGAGGGGCTGAAGTTCTCGGTGGTCCGCGATTTCTGTGGCCATGGCCTGGGTCAGGTCTTCCACCAGCC
GCCCAATGTCATGCATTTCGGCCGCAAGGGTCAGGGGATGACCCTGCGCGAAGGCATGATCTTCACCATCGAACCGATGA
TCAACACCGGCCGCGCCGATACCAAGATCCTGTCGGATGGCTGGACGGCGGTCACCCGCGACAAGTCGCTTTCGGCCCAG
TTCGAGCATTCGATCGGCGTGACCGCCGATGGCTGCGAGATTTTCACCCTGTCGCCCAAAGGCTGGCACTGCCCGCCCTA
TACCGAGGCGCCATGA

Upstream 100 bases:

>100_bases
AGCGAAGCCCCGCCGCGCCTAAAACAAAAGGGGCGGGTTCGGTTTCGGCACCCCATATATCTCCTTACCCCTTTTTCAGA
AACGATTGGACCGTTTTCCC

Downstream 100 bases:

>100_bases
CCCCGGCCTCGGGGGAGACGCCGCCCAACAAGGCGGTTGTGGCGCCCGAAAAGGCGCCCCTCCCCCATTATTCCGGGCAC
CGCGCCCGCCTGCGCGACCG

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MNQTAQRAQQVTIHGLEGFEGMRRAGRLAAETLDFITPYIVPGATTEDLDRLCAEFMADNGAISATLNYRGYPKSICTSI
NHVVCHGIPSEDKILHDGDIMNIDVTPILDGWYGDSSRMYYVGEPKVKAKRLVEATYECLMRGIAVVKPGATLGDIGYAI
QSYAEGLKFSVVRDFCGHGLGQVFHQPPNVMHFGRKGQGMTLREGMIFTIEPMINTGRADTKILSDGWTAVTRDKSLSAQ
FEHSIGVTADGCEIFTLSPKGWHCPPYTEAP

Sequences:

>Translated_271_residues
MNQTAQRAQQVTIHGLEGFEGMRRAGRLAAETLDFITPYIVPGATTEDLDRLCAEFMADNGAISATLNYRGYPKSICTSI
NHVVCHGIPSEDKILHDGDIMNIDVTPILDGWYGDSSRMYYVGEPKVKAKRLVEATYECLMRGIAVVKPGATLGDIGYAI
QSYAEGLKFSVVRDFCGHGLGQVFHQPPNVMHFGRKGQGMTLREGMIFTIEPMINTGRADTKILSDGWTAVTRDKSLSAQ
FEHSIGVTADGCEIFTLSPKGWHCPPYTEAP
>Mature_271_residues
MNQTAQRAQQVTIHGLEGFEGMRRAGRLAAETLDFITPYIVPGATTEDLDRLCAEFMADNGAISATLNYRGYPKSICTSI
NHVVCHGIPSEDKILHDGDIMNIDVTPILDGWYGDSSRMYYVGEPKVKAKRLVEATYECLMRGIAVVKPGATLGDIGYAI
QSYAEGLKFSVVRDFCGHGLGQVFHQPPNVMHFGRKGQGMTLREGMIFTIEPMINTGRADTKILSDGWTAVTRDKSLSAQ
FEHSIGVTADGCEIFTLSPKGWHCPPYTEAP

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=254, Percent_Identity=44.4881889763779, Blast_Score=226, Evalue=1e-59,
Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=37.7510040160643, Blast_Score=178, Evalue=5e-45,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=52.0161290322581, Blast_Score=281, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI71996291, Length=242, Percent_Identity=43.801652892562, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6323273, Length=259, Percent_Identity=40.5405405405405, Blast_Score=209, Evalue=3e-55,
Organism=Drosophila melanogaster, GI21355531, Length=256, Percent_Identity=43.75, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24583427, Length=237, Percent_Identity=43.0379746835443, Blast_Score=197, Evalue=4e-51,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29709; Mature: 29709

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTAQRAQQVTIHGLEGFEGMRRAGRLAAETLDFITPYIVPGATTEDLDRLCAEFMADN
CCHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
GAISATLNYRGYPKSICTSINHVVCHGIPSEDKILHDGDIMNIDVTPILDGWYGDSSRMY
CCEEEEEECCCCCHHHHHHHHHEEECCCCCCCCEEECCCEEEEEECEEECCEECCCCEEE
YVGEPKVKAKRLVEATYECLMRGIAVVKPGATLGDIGYAIQSYAEGLKFSVVRDFCGHGL
EECCCCHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCH
GQVFHQPPNVMHFGRKGQGMTLREGMIFTIEPMINTGRADTKILSDGWTAVTRDKSLSAQ
HHHHCCCCCCEECCCCCCCCEEECCEEEEEECCCCCCCCCCEEECCCCEEEECCCCCCHH
FEHSIGVTADGCEIFTLSPKGWHCPPYTEAP
HHHCCCCEECCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNQTAQRAQQVTIHGLEGFEGMRRAGRLAAETLDFITPYIVPGATTEDLDRLCAEFMADN
CCHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
GAISATLNYRGYPKSICTSINHVVCHGIPSEDKILHDGDIMNIDVTPILDGWYGDSSRMY
CCEEEEEECCCCCHHHHHHHHHEEECCCCCCCCEEECCCEEEEEECEEECCEECCCCEEE
YVGEPKVKAKRLVEATYECLMRGIAVVKPGATLGDIGYAIQSYAEGLKFSVVRDFCGHGL
EECCCCHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCH
GQVFHQPPNVMHFGRKGQGMTLREGMIFTIEPMINTGRADTKILSDGWTAVTRDKSLSAQ
HHHHCCCCCCEECCCCCCCCEEECCEEEEEECCCCCCCCCCEEECCCCEEEECCCCCCHH
FEHSIGVTADGCEIFTLSPKGWHCPPYTEAP
HHHCCCCEECCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]