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The map label for this gene is hupR1 [H]

Identifier: 83592031

GI number: 83592031

Start: 820548

End: 821720

Strand: Direct

Name: hupR1 [H]

Synonym: Rru_A0692

Alternate gene names: 83592031

Gene position: 820548-821720 (Clockwise)

Preceding gene: 83592030

Following gene: 83592034

Centisome position: 18.85

GC content: 65.39

Gene sequence:

>1173_bases
GTGAGCGATACCGTCTTGATCATCGACGACGACGCCAATCTGCTTTCGGCGATGAAACGCCAGCTGCGGGGTCGTTTCGC
CGTGACCACCGCCCAAAGCGGCGAAGAGGCCCTCGGCCTGCTTGGCGCCGGCGAGGCGCCGGCGGTGGTGTTGTGCGACA
TGCGCATGGGTGGCATGAACGGGGTGGAAACCCTGCGCAAGGTCCGCGACCTCGCGCCCGATACGGTGCGCATGATGTTG
ACGGGCAATGCCGACACCCAGACGGCGATCGACGCCATCAACGAAGGCAACATCTTCCGCTTCTTTTCCAAGCCTTGCAC
CCCGCAAGTGCTGGAAGCCGGGCTGGAAGCGGCGGTGGCCCAGTATCGTCTGGTGACCGCCGAACGCGACCTGCTGGAAA
AGACCCTGTCGGGCAGCATCCGGGTATTGATGGATATGCTGGCGCTGACCTATCCCCGGGGCTATGCCCGGGCCGCCCGC
CTGCGCGGCTGGGTGCGCAAGATGACGCGCGACAACAACATGCCCCACCGCTGGCAGCTTGATATCGCCTCGATGCTCGC
CCCGCTCGGCCTTGTCGCCCTACCCGAGGCGGTGCTGGCCAAGCTGCACCGCCGCGAGCCCTTGAGCGATGAGGAAAGGG
CGATGGTCGAACGCAGCCCCGAGGCGGCGCGCAATGTCATCAACCATATCCCCCGCCTCCAGGGGGTGGCCGAGATCGTT
TATTTGCAAAACCGCGGCTTTGACGGCAGCGGCTTTCCCCCCGAAGGGCCGAGCGGGGTGGATATCCCCTTTGATTCGCG
CCTGCTGCGCATCTTGAACGATCTGGGCGACGTGGTTGGCGACTCGGTGCCGCTGGCCGGTCATTTCGCCGAATTGGAGG
CCAATGCCCGGTGGTATGACGGGGCCTTGCTGCGCAAGGTACGGCTGTGTCTGGAAGCGCCGGCCGGCAAGGGGATCAAG
CCGGCCTTCCGCAAGCTTTCGACCGATACGTTGATCGCCGGCATGGTGGTGTCGGACGATGTGGTCGGAGAGGGCGGGCG
CTTGCTGCTGGCGGCCTTGACGCCGGTTTCCGAGGCCCATATCGAGCGCCTGCGCAACCTCGCCCGCCTGCGGGTGATCG
CCGATGCCATCCCGATCATCGTCGATGAACGCGGTCAGCCCAAAGTGGGATGA

Upstream 100 bases:

>100_bases
CGATAGGCGGGAGGCGAGCGGGGGGACTCTTGAGTTGAAATCAAAGGATTGACTCGCAGTCCGCCGCTTTGGGGGCGGCG
AGCCGTCAGGGAGACGCGGA

Downstream 100 bases:

>100_bases
GGGCGGCGTGTCGTGTTACGATGCCGCTTGGCCCGGTGTGGGGATAAGGATGGTCCACACCGTGCCCTGATCGGACACCA
CCGTGGCGCTGGCGCCGATC

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSDTVLIIDDDANLLSAMKRQLRGRFAVTTAQSGEEALGLLGAGEAPAVVLCDMRMGGMNGVETLRKVRDLAPDTVRMML
TGNADTQTAIDAINEGNIFRFFSKPCTPQVLEAGLEAAVAQYRLVTAERDLLEKTLSGSIRVLMDMLALTYPRGYARAAR
LRGWVRKMTRDNNMPHRWQLDIASMLAPLGLVALPEAVLAKLHRREPLSDEERAMVERSPEAARNVINHIPRLQGVAEIV
YLQNRGFDGSGFPPEGPSGVDIPFDSRLLRILNDLGDVVGDSVPLAGHFAELEANARWYDGALLRKVRLCLEAPAGKGIK
PAFRKLSTDTLIAGMVVSDDVVGEGGRLLLAALTPVSEAHIERLRNLARLRVIADAIPIIVDERGQPKVG

Sequences:

>Translated_390_residues
MSDTVLIIDDDANLLSAMKRQLRGRFAVTTAQSGEEALGLLGAGEAPAVVLCDMRMGGMNGVETLRKVRDLAPDTVRMML
TGNADTQTAIDAINEGNIFRFFSKPCTPQVLEAGLEAAVAQYRLVTAERDLLEKTLSGSIRVLMDMLALTYPRGYARAAR
LRGWVRKMTRDNNMPHRWQLDIASMLAPLGLVALPEAVLAKLHRREPLSDEERAMVERSPEAARNVINHIPRLQGVAEIV
YLQNRGFDGSGFPPEGPSGVDIPFDSRLLRILNDLGDVVGDSVPLAGHFAELEANARWYDGALLRKVRLCLEAPAGKGIK
PAFRKLSTDTLIAGMVVSDDVVGEGGRLLLAALTPVSEAHIERLRNLARLRVIADAIPIIVDERGQPKVG
>Mature_389_residues
SDTVLIIDDDANLLSAMKRQLRGRFAVTTAQSGEEALGLLGAGEAPAVVLCDMRMGGMNGVETLRKVRDLAPDTVRMMLT
GNADTQTAIDAINEGNIFRFFSKPCTPQVLEAGLEAAVAQYRLVTAERDLLEKTLSGSIRVLMDMLALTYPRGYARAARL
RGWVRKMTRDNNMPHRWQLDIASMLAPLGLVALPEAVLAKLHRREPLSDEERAMVERSPEAARNVINHIPRLQGVAEIVY
LQNRGFDGSGFPPEGPSGVDIPFDSRLLRILNDLGDVVGDSVPLAGHFAELEANARWYDGALLRKVRLCLEAPAGKGIKP
AFRKLSTDTLIAGMVVSDDVVGEGGRLLLAALTPVSEAHIERLRNLARLRVIADAIPIIVDERGQPKVG

Specific function: Probable member of the two-component regulatory system involved in the regulation of the [NiFe] hydrogenase activity. HupR1 is probably phosphorylated by the sensory component and then acts in conjunction with sigma-54 as a transcriptional activator [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=32, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 42479; Mature: 42348

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTVLIIDDDANLLSAMKRQLRGRFAVTTAQSGEEALGLLGAGEAPAVVLCDMRMGGMN
CCCCEEEEECCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCEEEEECCCCCCCC
GVETLRKVRDLAPDTVRMMLTGNADTQTAIDAINEGNIFRFFSKPCTPQVLEAGLEAAVA
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHH
QYRLVTAERDLLEKTLSGSIRVLMDMLALTYPRGYARAARLRGWVRKMTRDNNMPHRWQL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEH
DIASMLAPLGLVALPEAVLAKLHRREPLSDEERAMVERSPEAARNVINHIPRLQGVAEIV
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
YLQNRGFDGSGFPPEGPSGVDIPFDSRLLRILNDLGDVVGDSVPLAGHFAELEANARWYD
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHH
GALLRKVRLCLEAPAGKGIKPAFRKLSTDTLIAGMVVSDDVVGEGGRLLLAALTPVSEAH
HHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHEEEEECCCCCCCCCCEEEEECCCCHHHH
IERLRNLARLRVIADAIPIIVDERGQPKVG
HHHHHHHHHHHHHHHHHCEEECCCCCCCCC
>Mature Secondary Structure 
SDTVLIIDDDANLLSAMKRQLRGRFAVTTAQSGEEALGLLGAGEAPAVVLCDMRMGGMN
CCCEEEEECCHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCCEEEEECCCCCCCC
GVETLRKVRDLAPDTVRMMLTGNADTQTAIDAINEGNIFRFFSKPCTPQVLEAGLEAAVA
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHH
QYRLVTAERDLLEKTLSGSIRVLMDMLALTYPRGYARAARLRGWVRKMTRDNNMPHRWQL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEH
DIASMLAPLGLVALPEAVLAKLHRREPLSDEERAMVERSPEAARNVINHIPRLQGVAEIV
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
YLQNRGFDGSGFPPEGPSGVDIPFDSRLLRILNDLGDVVGDSVPLAGHFAELEANARWYD
EEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCHHH
GALLRKVRLCLEAPAGKGIKPAFRKLSTDTLIAGMVVSDDVVGEGGRLLLAALTPVSEAH
HHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHEEEEECCCCCCCCCCEEEEECCCCHHHH
IERLRNLARLRVIADAIPIIVDERGQPKVG
HHHHHHHHHHHHHHHHHCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1885559; 8497190; 2007559 [H]