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The map label for this gene is fba [H]

Identifier: 83591935

GI number: 83591935

Start: 708365

End: 709429

Strand: Direct

Name: fba [H]

Synonym: Rru_A0596

Alternate gene names: 83591935

Gene position: 708365-709429 (Clockwise)

Preceding gene: 83591934

Following gene: 83591936

Centisome position: 16.27

GC content: 62.54

Gene sequence:

>1065_bases
ATGGCTACGATTTCCCTACGCCAGCTTCTCGACCACGCCGCCGAAAACGGCTATGGCATGCCGGCGTTCAATGTGAACAA
CATGGAACAGGTCTTGGCGATCATGGACGCCGCCAAGAAGACCGACAGCCCGGTGATCCTCCAGGCCAGCCGCGGCGCGC
GCGGCTATGCCGGCGATATCATGATCAAGCACATGATCATGGCGGTGGCCGAGATGTATCCCGATATCCCCGTGTGCATG
CACCAGGACCACGGTAATTCGCTGGGCACCTGTCTGTCGGCGATTTCCGCCAGCTTCACCTCGGTGATGATGGACGGCTC
GCTCGAAGCCGACGCCAAGACCCCGGCCACCTATGAGTACAACTACGAGGTCACCGGCAAGGTCGCCGAATGCGCCCATC
TGGTCGGCGTGTCGGTGGAAGGCGAACTGGGTTGCCTGGGCTCGCTGGAAACCGGCGCCGGCGAAAAAGAGGACGGCCAC
GGCTTCGAAGGCACGCTCGATCATTCCCAGCTGCTGACCGACCCCGATCAGGCCGCCGATTTCGTCAAGCGCACCAAGGT
CGACGCCCTGGCCGTCGCCATCGGCACCAGCCACGGCGCCTATAAGTTCACCCGCAAGCCGACGGGCGACATCCTGGCGA
TGGGCGTGGTCAAGAAGATCCACGAGCGCCTGCCCAATACCCATCTGGTGATGCACGGGTCGTCAAGCGTGCCCCAGGAC
CTTCAGGACATCATCAACCAGTATGGCGGCGAAATGCCCCAGACCTATGGTGTGCCGGTCGAGGAAATCGTCGAAGGCAT
CAAGCACGGCGTGCGCAAGGTCAATATCGACACCGATTGCCGCATGGCGATCACCGGCGCCATCCGCAAGGTTTTCGCCG
AGAACAAGGCCGAATTCGATCCGCGCAAGTACCTGAAGCCGTCGATGACGGCGATGGAGAAGGTTTGCGTCGAGCGCTTC
GAGCAGTTCGGCGCCGCCGGCAATGCCTCGAAGATCCGCCCGATCGCCCTGGCCGACATGGCCAAGCGCTACGCCAGCGG
CAGCCTGGACCCGACCATTCAGTAG

Upstream 100 bases:

>100_bases
GTCGCGCCGCGCGGACGCTGTATCGTTCGGCAGAGTGCCGGGAACCGGTTTCATAGGGCCTTGGTCAACAAGCCCGATTA
TAGGTAAGGAGACGCCTTCG

Downstream 100 bases:

>100_bases
TCTCCTGGCCAGTAACACCCGGCCAGTACCACCCTGGCGCGGTCCTGCCGCCGCCAACACAGCCCCGCCCGATCCGGCGG
GGCTTTTTCATGGGCATGGG

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MATISLRQLLDHAAENGYGMPAFNVNNMEQVLAIMDAAKKTDSPVILQASRGARGYAGDIMIKHMIMAVAEMYPDIPVCM
HQDHGNSLGTCLSAISASFTSVMMDGSLEADAKTPATYEYNYEVTGKVAECAHLVGVSVEGELGCLGSLETGAGEKEDGH
GFEGTLDHSQLLTDPDQAADFVKRTKVDALAVAIGTSHGAYKFTRKPTGDILAMGVVKKIHERLPNTHLVMHGSSSVPQD
LQDIINQYGGEMPQTYGVPVEEIVEGIKHGVRKVNIDTDCRMAITGAIRKVFAENKAEFDPRKYLKPSMTAMEKVCVERF
EQFGAAGNASKIRPIALADMAKRYASGSLDPTIQ

Sequences:

>Translated_354_residues
MATISLRQLLDHAAENGYGMPAFNVNNMEQVLAIMDAAKKTDSPVILQASRGARGYAGDIMIKHMIMAVAEMYPDIPVCM
HQDHGNSLGTCLSAISASFTSVMMDGSLEADAKTPATYEYNYEVTGKVAECAHLVGVSVEGELGCLGSLETGAGEKEDGH
GFEGTLDHSQLLTDPDQAADFVKRTKVDALAVAIGTSHGAYKFTRKPTGDILAMGVVKKIHERLPNTHLVMHGSSSVPQD
LQDIINQYGGEMPQTYGVPVEEIVEGIKHGVRKVNIDTDCRMAITGAIRKVFAENKAEFDPRKYLKPSMTAMEKVCVERF
EQFGAAGNASKIRPIALADMAKRYASGSLDPTIQ
>Mature_353_residues
ATISLRQLLDHAAENGYGMPAFNVNNMEQVLAIMDAAKKTDSPVILQASRGARGYAGDIMIKHMIMAVAEMYPDIPVCMH
QDHGNSLGTCLSAISASFTSVMMDGSLEADAKTPATYEYNYEVTGKVAECAHLVGVSVEGELGCLGSLETGAGEKEDGHG
FEGTLDHSQLLTDPDQAADFVKRTKVDALAVAIGTSHGAYKFTRKPTGDILAMGVVKKIHERLPNTHLVMHGSSSVPQDL
QDIINQYGGEMPQTYGVPVEEIVEGIKHGVRKVNIDTDCRMAITGAIRKVFAENKAEFDPRKYLKPSMTAMEKVCVERFE
QFGAAGNASKIRPIALADMAKRYASGSLDPTIQ

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=330, Percent_Identity=32.1212121212121, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=29.1793313069909, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788072, Length=325, Percent_Identity=30.4615384615385, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789293, Length=371, Percent_Identity=24.5283018867925, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322790, Length=382, Percent_Identity=25.3926701570681, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38155; Mature: 38024

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATISLRQLLDHAAENGYGMPAFNVNNMEQVLAIMDAAKKTDSPVILQASRGARGYAGDI
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
MIKHMIMAVAEMYPDIPVCMHQDHGNSLGTCLSAISASFTSVMMDGSLEADAKTPATYEY
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
NYEVTGKVAECAHLVGVSVEGELGCLGSLETGAGEKEDGHGFEGTLDHSQLLTDPDQAAD
CEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
FVKRTKVDALAVAIGTSHGAYKFTRKPTGDILAMGVVKKIHERLPNTHLVMHGSSSVPQD
HHHHHHHHHHEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
LQDIINQYGGEMPQTYGVPVEEIVEGIKHGVRKVNIDTDCRMAITGAIRKVFAENKAEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PRKYLKPSMTAMEKVCVERFEQFGAAGNASKIRPIALADMAKRYASGSLDPTIQ
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATISLRQLLDHAAENGYGMPAFNVNNMEQVLAIMDAAKKTDSPVILQASRGARGYAGDI
CCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHH
MIKHMIMAVAEMYPDIPVCMHQDHGNSLGTCLSAISASFTSVMMDGSLEADAKTPATYEY
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
NYEVTGKVAECAHLVGVSVEGELGCLGSLETGAGEKEDGHGFEGTLDHSQLLTDPDQAAD
CEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
FVKRTKVDALAVAIGTSHGAYKFTRKPTGDILAMGVVKKIHERLPNTHLVMHGSSSVPQD
HHHHHHHHHHEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHH
LQDIINQYGGEMPQTYGVPVEEIVEGIKHGVRKVNIDTDCRMAITGAIRKVFAENKAEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PRKYLKPSMTAMEKVCVERFEQFGAAGNASKIRPIALADMAKRYASGSLDPTIQ
HHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA