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The map label for this gene is braD [H]

Identifier: 83591923

GI number: 83591923

Start: 693637

End: 695478

Strand: Direct

Name: braD [H]

Synonym: Rru_A0584

Alternate gene names: 83591923

Gene position: 693637-695478 (Clockwise)

Preceding gene: 83591922

Following gene: 83591924

Centisome position: 15.94

GC content: 70.36

Gene sequence:

>1842_bases
TTGTCGGTCGATTTCCTTATCGTTCAGTTTCTGGGCGGGCTGGCCAGCGCCTCGTCGCTGTTCCTGGTCGCCGCCGGGCT
GTCGATCATTTTTGGCGTGACCCGGGTGGTGAATTTCGCCCATGGCACGCTGTTCATGATCGGCGCCTATCTGGCCTATA
CCCTGGCCGAGACCCTGGGCCTTGGCTTCTGGCCGGCCCTGCTGCTGGCGCCGCTGGCCGTCGGCGGCCTGGGCGCCCTG
ATCGAGATCGGCCTGCTGCGGCGGATCTATCGCGCCCCCGAGCTTTTCCAACTGGTCGCCACCTTCGCCCTGGTGCTGAT
CGCTAGCGACGTGGTGCCGATGATCTGGGGGCCGGAGGACCTGTTGGGGCCGCGCGCCCCGGGCCTGGGCGGCGCCGTAA
GCGTGATGGGCCGGGCGGTTCCCGAGTATGATCTGTTCCTAATCGCCCTGGGACCCCTGGTTCTGGGCGCCCTGTGGCTG
GTGTTCACCCGCACCCGCTGGGGCCTGCTGGTGCGCGCGGCGACCGAGGACCGCGAGATGGTGGCGGCGCTCGGCACCGA
TCAGCGCTGGCTGTTCACCGGGGTCTTCGCTCTTGGCGCGCTGCTGGCCGGCCTGGGCGGTGCCCTGGCCCTGCCGCGCG
AGGCCATCGGCCATGGCATGGACGCCGGGGTGATCGTTCAGGCTTTCGTCGTTGTCGTCGTCGGCGGCATGGGCAGCGTG
CCCGGCGCCTATCTGGCCGCCGTGCTGCTGGGGCTGGTCAACGCCTTCGGTGTCGCCTTCTTTCCCCAGGGCACGCTGGT
GACCATGGGGCTGGTGATGGGGGCGGTGCTGATCGTGCGTCCGCGCGGCCTTCTTGGCCGGATCGAAAGCGAGGGCGGCG
TTTCCGCCGTGGGACCGGGGCCCCGGCTGCGTCCGGCGAGCGGCAAAGGCCGGCTGCTGTGGGGCCTGGGCGTGGTCCTG
GTGCTCGCCGCGCCACGGTTTCTCGATGCCTATGGCCTGTCGCTGCTGTGCGAGGCGCTGATCCTGGCGCTGTCGGCCAG
CGCCTTGCAGCTGCTGATGGGGACCGGCGGCATGGTCAGCTTCGGCCATGGGGCGTTCTTTGGCCTGGGGGCTTACGGAA
CGGCGGTGGCGGTGGTTCAGGGCGGGCTGTCTCTGCCCATCGCCCTGGCCTGCGCGCCCTTGGCCGGGGGGCTGGGCGGG
CTGCTGGTCGGTTGGCTGATCAGCAGGCTGTCGGGGGTTTATCTGGCGATGCTGACCCTGGCCTTCGCCGAAATCATCCA
TGCCCTGGCCATTCAGGCGGTTGGGGTGACCGGCGGCGACAATGGCCTGATCGGCGTCTGGCCGCCGCCCTGGGCCGGTG
ATCCCGCCGTGTTTGCCTGGTTGGTGATGGCGATCTGCCTGCCCGCGCTGTTTGGTCTGCGCGCCCTGGCCCTTGGCGAA
TTCGGCCGCCGCCTGCGGGCCCTGCGCGATGCCCGCAGCCGGGCCGAGGCCAGCGGCATTGCCGCCGCCCGCCTGCACGC
GCTCACCTTCGCCATCGTCGGCGCCGGCGCCGGGTTGGCCGGCGGGCTGTTCGCCTTCCTCAAGGGCAGCGTCTTTCCGG
CGATCACCGCCATTCCAACCAGTGTCGACGCCCTGGTGATGGTGCTGCTGGGTGGCCTGCATGCCCTGGCCGGACCGCTG
GTCGGCGCCTTCTTGTATTTGGGCCTGGAATCGGTGGTCGCGGCGCGTACCGATCTTTGGCAATTGGTGGTCGGGCTGGT
GGTGCTCGGGCTGGTGCTGGTCTTCCCGCAAGGGGTGGCCGGCGCCGCCGGGCGATTGGCGCGCCGGGGACGGCCCCAAT
GA

Upstream 100 bases:

>100_bases
GTCTGGGAAGCCGTGGCCGGGGGGCGGCGCGACGTTCGCGTGGACCGCGAGCGGGTGAGCGCGTAAAAAGGGCGCTCAAC
CACCCTGGGGCTTGCGCGGT

Downstream 100 bases:

>100_bases
TCCCGCCCGCGCCAACGGGGGCGCCGCCGCTGCTGGTGGTCGACGGGCTGGTCAAGGCCTTTGGCGGGGTGCGCGCCGTC
GATGGCGTGTCGTTCGTTTT

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 612

Protein sequence:

>613_residues
MSVDFLIVQFLGGLASASSLFLVAAGLSIIFGVTRVVNFAHGTLFMIGAYLAYTLAETLGLGFWPALLLAPLAVGGLGAL
IEIGLLRRIYRAPELFQLVATFALVLIASDVVPMIWGPEDLLGPRAPGLGGAVSVMGRAVPEYDLFLIALGPLVLGALWL
VFTRTRWGLLVRAATEDREMVAALGTDQRWLFTGVFALGALLAGLGGALALPREAIGHGMDAGVIVQAFVVVVVGGMGSV
PGAYLAAVLLGLVNAFGVAFFPQGTLVTMGLVMGAVLIVRPRGLLGRIESEGGVSAVGPGPRLRPASGKGRLLWGLGVVL
VLAAPRFLDAYGLSLLCEALILALSASALQLLMGTGGMVSFGHGAFFGLGAYGTAVAVVQGGLSLPIALACAPLAGGLGG
LLVGWLISRLSGVYLAMLTLAFAEIIHALAIQAVGVTGGDNGLIGVWPPPWAGDPAVFAWLVMAICLPALFGLRALALGE
FGRRLRALRDARSRAEASGIAAARLHALTFAIVGAGAGLAGGLFAFLKGSVFPAITAIPTSVDALVMVLLGGLHALAGPL
VGAFLYLGLESVVAARTDLWQLVVGLVVLGLVLVFPQGVAGAAGRLARRGRPQ

Sequences:

>Translated_613_residues
MSVDFLIVQFLGGLASASSLFLVAAGLSIIFGVTRVVNFAHGTLFMIGAYLAYTLAETLGLGFWPALLLAPLAVGGLGAL
IEIGLLRRIYRAPELFQLVATFALVLIASDVVPMIWGPEDLLGPRAPGLGGAVSVMGRAVPEYDLFLIALGPLVLGALWL
VFTRTRWGLLVRAATEDREMVAALGTDQRWLFTGVFALGALLAGLGGALALPREAIGHGMDAGVIVQAFVVVVVGGMGSV
PGAYLAAVLLGLVNAFGVAFFPQGTLVTMGLVMGAVLIVRPRGLLGRIESEGGVSAVGPGPRLRPASGKGRLLWGLGVVL
VLAAPRFLDAYGLSLLCEALILALSASALQLLMGTGGMVSFGHGAFFGLGAYGTAVAVVQGGLSLPIALACAPLAGGLGG
LLVGWLISRLSGVYLAMLTLAFAEIIHALAIQAVGVTGGDNGLIGVWPPPWAGDPAVFAWLVMAICLPALFGLRALALGE
FGRRLRALRDARSRAEASGIAAARLHALTFAIVGAGAGLAGGLFAFLKGSVFPAITAIPTSVDALVMVLLGGLHALAGPL
VGAFLYLGLESVVAARTDLWQLVVGLVVLGLVLVFPQGVAGAAGRLARRGRPQ
>Mature_612_residues
SVDFLIVQFLGGLASASSLFLVAAGLSIIFGVTRVVNFAHGTLFMIGAYLAYTLAETLGLGFWPALLLAPLAVGGLGALI
EIGLLRRIYRAPELFQLVATFALVLIASDVVPMIWGPEDLLGPRAPGLGGAVSVMGRAVPEYDLFLIALGPLVLGALWLV
FTRTRWGLLVRAATEDREMVAALGTDQRWLFTGVFALGALLAGLGGALALPREAIGHGMDAGVIVQAFVVVVVGGMGSVP
GAYLAAVLLGLVNAFGVAFFPQGTLVTMGLVMGAVLIVRPRGLLGRIESEGGVSAVGPGPRLRPASGKGRLLWGLGVVLV
LAAPRFLDAYGLSLLCEALILALSASALQLLMGTGGMVSFGHGAFFGLGAYGTAVAVVQGGLSLPIALACAPLAGGLGGL
LVGWLISRLSGVYLAMLTLAFAEIIHALAIQAVGVTGGDNGLIGVWPPPWAGDPAVFAWLVMAICLPALFGLRALALGEF
GRRLRALRDARSRAEASGIAAARLHALTFAIVGAGAGLAGGLFAFLKGSVFPAITAIPTSVDALVMVLLGGLHALAGPLV
GAFLYLGLESVVAARTDLWQLVVGLVVLGLVLVFPQGVAGAAGRLARRGRPQ

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=323, Percent_Identity=27.2445820433437, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1789865, Length=278, Percent_Identity=27.3381294964029, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 62551; Mature: 62419

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00147 ARGINASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDFLIVQFLGGLASASSLFLVAAGLSIIFGVTRVVNFAHGTLFMIGAYLAYTLAETLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGFWPALLLAPLAVGGLGALIEIGLLRRIYRAPELFQLVATFALVLIASDVVPMIWGPED
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHCCCCHH
LLGPRAPGLGGAVSVMGRAVPEYDLFLIALGPLVLGALWLVFTRTRWGLLVRAATEDREM
HCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHH
VAALGTDQRWLFTGVFALGALLAGLGGALALPREAIGHGMDAGVIVQAFVVVVVGGMGSV
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCC
PGAYLAAVLLGLVNAFGVAFFPQGTLVTMGLVMGAVLIVRPRGLLGRIESEGGVSAVGPG
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCC
PRLRPASGKGRLLWGLGVVLVLAAPRFLDAYGLSLLCEALILALSASALQLLMGTGGMVS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FGHGAFFGLGAYGTAVAVVQGGLSLPIALACAPLAGGLGGLLVGWLISRLSGVYLAMLTL
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AFAEIIHALAIQAVGVTGGDNGLIGVWPPPWAGDPAVFAWLVMAICLPALFGLRALALGE
HHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FGRRLRALRDARSRAEASGIAAARLHALTFAIVGAGAGLAGGLFAFLKGSVFPAITAIPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHCCC
SVDALVMVLLGGLHALAGPLVGAFLYLGLESVVAARTDLWQLVVGLVVLGLVLVFPQGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAAGRLARRGRPQ
HHHHHHHHCCCCC
>Mature Secondary Structure 
SVDFLIVQFLGGLASASSLFLVAAGLSIIFGVTRVVNFAHGTLFMIGAYLAYTLAETLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGFWPALLLAPLAVGGLGALIEIGLLRRIYRAPELFQLVATFALVLIASDVVPMIWGPED
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHCCCCHH
LLGPRAPGLGGAVSVMGRAVPEYDLFLIALGPLVLGALWLVFTRTRWGLLVRAATEDREM
HCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHH
VAALGTDQRWLFTGVFALGALLAGLGGALALPREAIGHGMDAGVIVQAFVVVVVGGMGSV
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCC
PGAYLAAVLLGLVNAFGVAFFPQGTLVTMGLVMGAVLIVRPRGLLGRIESEGGVSAVGPG
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCC
PRLRPASGKGRLLWGLGVVLVLAAPRFLDAYGLSLLCEALILALSASALQLLMGTGGMVS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FGHGAFFGLGAYGTAVAVVQGGLSLPIALACAPLAGGLGGLLVGWLISRLSGVYLAMLTL
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AFAEIIHALAIQAVGVTGGDNGLIGVWPPPWAGDPAVFAWLVMAICLPALFGLRALALGE
HHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FGRRLRALRDARSRAEASGIAAARLHALTFAIVGAGAGLAGGLFAFLKGSVFPAITAIPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHCCC
SVDALVMVLLGGLHALAGPLVGAFLYLGLESVVAARTDLWQLVVGLVVLGLVLVFPQGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GAAGRLARRGRPQ
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]