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The map label for this gene is aer [C]

Identifier: 83591915

GI number: 83591915

Start: 683909

End: 685975

Strand: Direct

Name: aer [C]

Synonym: Rru_A0576

Alternate gene names: 83591915

Gene position: 683909-685975 (Clockwise)

Preceding gene: 83591914

Following gene: 83591917

Centisome position: 15.71

GC content: 69.76

Gene sequence:

>2067_bases
ATGTCATTGCGATCAAAGACTCTGACGACCGTTCTGGTCGGATTCTTTATCGGTTACGGGATTCTGGTCGGCATCGCCTG
GATCACCCAACGCGACGAGGCCGAACGGACCGGGCGCGCCGAACTGGATCTGGAGGCCCGCGCCCAGTCGCGGATCGCCG
GCGAATTCGTCGGCGAGGTGTTGACGGCGACGCGGACCATGGCCGGGGCGATCAGCGGTCTGGTCGGCGATGACCTGCGC
GACCGCGAGGTCGTGGGGCGGCTGGTGCGCGAGACGGTGCGCATCAACCCCGCCGTGGTCGGCGGCGGCACCGGCTGGGC
GGCCGATGGCTTCGACGGGGCCGACGCGTCGTTCCCGGGCAAGGCCTTCTCCGACGCCAAGGGCCGCTTCGTTCCCTATT
TCTATCGCCAAGCCGATGGTCAGATTGGCTTCGAGCCGCTGGTCATGGACGATGTGCAATCCACCGAGTCCTGGTACGGC
TTTCCCTTGCGCGAGGGCCGGCCGACGGTCACGCCGCCCTATCTTTACCCGGTCAACGGGGTGGAGGTGCTGATGACCAC
CGCCTCGGCGCCGATCATCGGCAAGGAGGGCAAGGCGGTCGCCGTGGCCACCTTGGATATGGCGCTCGAAACCATCCAAC
GCCAAATCGCCGATATCCATCCCTTCGGCGCCGGCTTCGCCGCCGTCTTGTCGGCCGATGGCCAATGGGTCGCCCATCCC
GACACGGCCCGCCTCGGCCGGCCGGCCGATCACGCCGAAGTGGGCGAGATCCTCGCCGCCACCGCCGCCGGTCGTGCCCT
GCAAGACACGGTGTCCGATCCGCAGACCGGCGAGCCTTTGCTGCGGGTGGCGGTGCCGATCGCCTTTTCGGGGGCGCCGG
AAACCTGGGCCTTTATCCTCAGCGTTCCCGAATCCGCCGTGATGGCCGGGGCGATCGAAACCCGCAACCGGCTGATCTTC
GCCGGCCTGGGCGTGCTCGCCCTGTCGCTGATCGGCTTGTGGCTGCTTTCGGGGCGGCTGGTCGGGCCGATCACCCGCAT
GACGGCGCTGATGCACCGGCTAGCGGCGGGCGATACCGGCGTGGTGGTGACGGGAACCGAACGCGGCGACGAATTCGGCG
AGATGGCCAAGGCGCTTCAGACCTTCAAGGACAACGCCCTGGCCAAGATCGCGCTGGAGGAGGAGGGCGAGAGGGCCAAA
CGTCAGGCCGAGGAGCGCCGCCGCGCCGATCTGGCCACCCTGGCCGACCGCTTCGAGCGTGAGATCGAAGGGCTGGTCAC
CCTGGTGGGGACCGCCGTCGACCAGATGACCAAGGGGGCCGGCCGGTCGGTCGAGCGCACCGAGGCCAATGCCCTTTATT
CCGATCAGGCGGCGCGGACCGCCGAGGAAATGGCCGCCGATATCGGCCGGGTCGCCGAAGCCGTGGAGGAGATGGCGCGC
GCCGTGACCGGCATCGGCGAGCGGGTGACGCGGGCCAATGCCATCGCCGTCGAGGGCGGCAGTTCCGCCCGCGCCGCCGT
CGGCCGGGTCTCGGCCCTGGTCGGCGCGGCCGATCGCATCGGCGATGTCGTCACCCTGATCACCACCATCGCCAGCCAGA
CCAACCTGCTGGCCTTGAACGCGACGATCGAGGCGGCACGGGCCGGTGATGCCGGCAAGGGCTTCGCCGTGGTCGCCGGC
GAGGTCAAGACCCTGGCCAATCAAACGGCGCGGGCTACCGAACAGATCGCCGAACAGGTGGCGGCCATCCAGCGCGAAAC
CGCCGATGCCGCCCGCGAGATCGAAAGCGTCGCCGGGGTGATCGGCGCCATCGGCGATCTCAACGCCCAGGTCGCCCAGG
CCATCGGTGATCAGGGGCAAGCCGTGGCCGGGATCGGCCAGATCGTCGTCGCCACGGTCAGCGGCGCCGGCAGCTTAAGT
GAAACCGCCCGGGGGGTCGCCGCCCGCTCGGCCGAGGGCGGCGAGGCGGCCCGCGCCATGGGCCGCGATGTCGCCGATCT
GCACCAGCGGGTCGGCGAGCTTGGCAAGACCGTCGACGCCTTCGTCGGCTCGCTGCGCGCCGGCTGA

Upstream 100 bases:

>100_bases
CCCGGCCGCTGCCGGGGGTGTCATAAAACCGCCAGCGACGGAGGGCGGAAGACCCGTTACAAGACTCCCCAGGGACCACA
AGGCCTGGGGGGCTTGGCTG

Downstream 100 bases:

>100_bases
GGTCTTGGGCGTCGCGTTCCCGTCTAGGCGGCGGGGGCGGGGACGATCAGGGATACCGGCTCGGCGGCCATGACGATATC
GACGGGCATATGGGCGACCG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MSLRSKTLTTVLVGFFIGYGILVGIAWITQRDEAERTGRAELDLEARAQSRIAGEFVGEVLTATRTMAGAISGLVGDDLR
DREVVGRLVRETVRINPAVVGGGTGWAADGFDGADASFPGKAFSDAKGRFVPYFYRQADGQIGFEPLVMDDVQSTESWYG
FPLREGRPTVTPPYLYPVNGVEVLMTTASAPIIGKEGKAVAVATLDMALETIQRQIADIHPFGAGFAAVLSADGQWVAHP
DTARLGRPADHAEVGEILAATAAGRALQDTVSDPQTGEPLLRVAVPIAFSGAPETWAFILSVPESAVMAGAIETRNRLIF
AGLGVLALSLIGLWLLSGRLVGPITRMTALMHRLAAGDTGVVVTGTERGDEFGEMAKALQTFKDNALAKIALEEEGERAK
RQAEERRRADLATLADRFEREIEGLVTLVGTAVDQMTKGAGRSVERTEANALYSDQAARTAEEMAADIGRVAEAVEEMAR
AVTGIGERVTRANAIAVEGGSSARAAVGRVSALVGAADRIGDVVTLITTIASQTNLLALNATIEAARAGDAGKGFAVVAG
EVKTLANQTARATEQIAEQVAAIQRETADAAREIESVAGVIGAIGDLNAQVAQAIGDQGQAVAGIGQIVVATVSGAGSLS
ETARGVAARSAEGGEAARAMGRDVADLHQRVGELGKTVDAFVGSLRAG

Sequences:

>Translated_688_residues
MSLRSKTLTTVLVGFFIGYGILVGIAWITQRDEAERTGRAELDLEARAQSRIAGEFVGEVLTATRTMAGAISGLVGDDLR
DREVVGRLVRETVRINPAVVGGGTGWAADGFDGADASFPGKAFSDAKGRFVPYFYRQADGQIGFEPLVMDDVQSTESWYG
FPLREGRPTVTPPYLYPVNGVEVLMTTASAPIIGKEGKAVAVATLDMALETIQRQIADIHPFGAGFAAVLSADGQWVAHP
DTARLGRPADHAEVGEILAATAAGRALQDTVSDPQTGEPLLRVAVPIAFSGAPETWAFILSVPESAVMAGAIETRNRLIF
AGLGVLALSLIGLWLLSGRLVGPITRMTALMHRLAAGDTGVVVTGTERGDEFGEMAKALQTFKDNALAKIALEEEGERAK
RQAEERRRADLATLADRFEREIEGLVTLVGTAVDQMTKGAGRSVERTEANALYSDQAARTAEEMAADIGRVAEAVEEMAR
AVTGIGERVTRANAIAVEGGSSARAAVGRVSALVGAADRIGDVVTLITTIASQTNLLALNATIEAARAGDAGKGFAVVAG
EVKTLANQTARATEQIAEQVAAIQRETADAAREIESVAGVIGAIGDLNAQVAQAIGDQGQAVAGIGQIVVATVSGAGSLS
ETARGVAARSAEGGEAARAMGRDVADLHQRVGELGKTVDAFVGSLRAG
>Mature_687_residues
SLRSKTLTTVLVGFFIGYGILVGIAWITQRDEAERTGRAELDLEARAQSRIAGEFVGEVLTATRTMAGAISGLVGDDLRD
REVVGRLVRETVRINPAVVGGGTGWAADGFDGADASFPGKAFSDAKGRFVPYFYRQADGQIGFEPLVMDDVQSTESWYGF
PLREGRPTVTPPYLYPVNGVEVLMTTASAPIIGKEGKAVAVATLDMALETIQRQIADIHPFGAGFAAVLSADGQWVAHPD
TARLGRPADHAEVGEILAATAAGRALQDTVSDPQTGEPLLRVAVPIAFSGAPETWAFILSVPESAVMAGAIETRNRLIFA
GLGVLALSLIGLWLLSGRLVGPITRMTALMHRLAAGDTGVVVTGTERGDEFGEMAKALQTFKDNALAKIALEEEGERAKR
QAEERRRADLATLADRFEREIEGLVTLVGTAVDQMTKGAGRSVERTEANALYSDQAARTAEEMAADIGRVAEAVEEMARA
VTGIGERVTRANAIAVEGGSSARAAVGRVSALVGAADRIGDVVTLITTIASQTNLLALNATIEAARAGDAGKGFAVVAGE
VKTLANQTARATEQIAEQVAAIQRETADAAREIESVAGVIGAIGDLNAQVAQAIGDQGQAVAGIGQIVVATVSGAGSLSE
TARGVAARSAEGGEAARAMGRDVADLHQRVGELGKTVDAFVGSLRAG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=220, Percent_Identity=30.4545454545455, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787690, Length=229, Percent_Identity=30.5676855895196, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788194, Length=190, Percent_Identity=32.1052631578947, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788195, Length=229, Percent_Identity=28.82096069869, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI2367378, Length=262, Percent_Identity=27.0992366412214, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71576; Mature: 71445

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRSKTLTTVLVGFFIGYGILVGIAWITQRDEAERTGRAELDLEARAQSRIAGEFVGEV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LTATRTMAGAISGLVGDDLRDREVVGRLVRETVRINPAVVGGGTGWAADGFDGADASFPG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCC
KAFSDAKGRFVPYFYRQADGQIGFEPLVMDDVQSTESWYGFPLREGRPTVTPPYLYPVNG
CCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHCCHHHCCCCCCCCCCCCCCCEEECCCC
VEVLMTTASAPIIGKEGKAVAVATLDMALETIQRQIADIHPFGAGFAAVLSADGQWVAHP
CEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECC
DTARLGRPADHAEVGEILAATAAGRALQDTVSDPQTGEPLLRVAVPIAFSGAPETWAFIL
CHHHCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHEEEEEECCCCCCEEEEE
SVPESAVMAGAIETRNRLIFAGLGVLALSLIGLWLLSGRLVGPITRMTALMHRLAAGDTG
ECCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
VVVTGTERGDEFGEMAKALQTFKDNALAKIALEEEGERAKRQAEERRRADLATLADRFER
EEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIEGLVTLVGTAVDQMTKGAGRSVERTEANALYSDQAARTAEEMAADIGRVAEAVEEMAR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTGIGERVTRANAIAVEGGSSARAAVGRVSALVGAADRIGDVVTLITTIASQTNLLALN
HHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
ATIEAARAGDAGKGFAVVAGEVKTLANQTARATEQIAEQVAAIQRETADAAREIESVAGV
CCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAIGDLNAQVAQAIGDQGQAVAGIGQIVVATVSGAGSLSETARGVAARSAEGGEAARAM
HHHHHCCHHHHHHHHCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHH
GRDVADLHQRVGELGKTVDAFVGSLRAG
CCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLRSKTLTTVLVGFFIGYGILVGIAWITQRDEAERTGRAELDLEARAQSRIAGEFVGEV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LTATRTMAGAISGLVGDDLRDREVVGRLVRETVRINPAVVGGGTGWAADGFDGADASFPG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCC
KAFSDAKGRFVPYFYRQADGQIGFEPLVMDDVQSTESWYGFPLREGRPTVTPPYLYPVNG
CCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHCCHHHCCCCCCCCCCCCCCCEEECCCC
VEVLMTTASAPIIGKEGKAVAVATLDMALETIQRQIADIHPFGAGFAAVLSADGQWVAHP
CEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECC
DTARLGRPADHAEVGEILAATAAGRALQDTVSDPQTGEPLLRVAVPIAFSGAPETWAFIL
CHHHCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCHHHHEEEEEECCCCCCEEEEE
SVPESAVMAGAIETRNRLIFAGLGVLALSLIGLWLLSGRLVGPITRMTALMHRLAAGDTG
ECCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
VVVTGTERGDEFGEMAKALQTFKDNALAKIALEEEGERAKRQAEERRRADLATLADRFER
EEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIEGLVTLVGTAVDQMTKGAGRSVERTEANALYSDQAARTAEEMAADIGRVAEAVEEMAR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVTGIGERVTRANAIAVEGGSSARAAVGRVSALVGAADRIGDVVTLITTIASQTNLLALN
HHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
ATIEAARAGDAGKGFAVVAGEVKTLANQTARATEQIAEQVAAIQRETADAAREIESVAGV
CCHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAIGDLNAQVAQAIGDQGQAVAGIGQIVVATVSGAGSLSETARGVAARSAEGGEAARAM
HHHHHCCHHHHHHHHCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHH
GRDVADLHQRVGELGKTVDAFVGSLRAG
CCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]