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The map label for this gene is fecD [H]

Identifier: 83591830

GI number: 83591830

Start: 576212

End: 577213

Strand: Direct

Name: fecD [H]

Synonym: Rru_A0490

Alternate gene names: 83591830

Gene position: 576212-577213 (Clockwise)

Preceding gene: 83591829

Following gene: 83591831

Centisome position: 13.24

GC content: 72.16

Gene sequence:

>1002_bases
ATGGGCGGTGATCGCGCCTTCGCAGCCCTTCTCGCCGGACTCGGCCTGCTGGTCGTGGCCTTGTTCGCCGTCGCCCTGCT
GGTCGGGCCGGCGGGATTGGCGCCGCGCGCCGCCCTGGTCGCCCTGATCAGCGGCGACGCCAGCCCCGCCGCCCTGGTGA
TGCGCGAGATCCGTTTGCCGCGCGCCCTGCTCGCCCTGCTGGTGGGCGGGTCGCTTGGGCTGTCGGGGGCGGCGTTGCAG
GGCTATTTGCGCAATCCTTTGGCCGAGCCCGGATTGCTTGGCGTCGGCGCCAGCGCCAGCCTGGGGGCGGTGGTGGCGAT
CTATAGCGGTCTGGCCGCCGGCTTCGCCCTGGCCCTGCCGCTTTGCGCCCTGGCCGGAGCCCTGATCGCCGTGGTTCTGG
TCGGCGTCCTGGCCGGACGGGCCGCCCATCCCCTGACCCTGATCCTGGCCGGCATCGCCGTCTCCAGTTTGGCCACCGCC
CTGACCTCGCTGGCGCTCAATCTGTCGACCAATCCCTTCGCGGCGATGGAGATCGTGTTCTGGATGTTGGGCTCGCTTGA
AAACCGCTCGATGAGCCATGTGCTGCTGGCCGGGCCGTTCATCGCCTTGGGCTGGGTATTGCTCGCCCGCCTGGGGCCGG
CGCTTGACGCCCTGACCCTGGGCGAGGAGGCGGCCGCCACCTTGGGAATCTCCCTGGGGCGGACGCGGGCCCTGGTCGTG
CTCGGCACCGCTTCGGCGGTGGGGGCGGCGACGGCGGTGGCCGGCGCCGTCGGCTTCATCGGGCTGGTGGTTCCCCATCT
GCTGCGGCCGCTGGTCGGCGGCCGGCCCTCGCGCCTGCTGGCGGCCAGCACCCTGGGCGGGGCGGCGATGCTGCTGGTGA
CGGATTTGGCGGTGCGGCTGATCGCCCCCGAGCGCGATCTCAAGCTTGGCGTCGTCACCGCCCTGGTCGGCGCGCCGTTT
TTCCTGTGGCTGCTGGCGCGGATGCGCAAGGACGCGTTATGA

Upstream 100 bases:

>100_bases
GCGCTCTGCGGCACACCGATGGTGGTCGAGGCCGTCGCCCGGCTGGCCGCCGCCCGTCCGCCATCCCGCCTTGCCCTGGG
TGCGGTGGCCGGAGCCGACG

Downstream 100 bases:

>100_bases
GCCTGCTGCGCTGCGCCAGGGTCAGCGTGGTTCTGGGCGGGCGCCCGGTGGTGAGCGACGCGTCGTTCACCGTCGAACCG
GGGGAATGCGTTGGTCTGAT

Product: transport system permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Iron(III) dicitrate transport system permease protein fecD [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MGGDRAFAALLAGLGLLVVALFAVALLVGPAGLAPRAALVALISGDASPAALVMREIRLPRALLALLVGGSLGLSGAALQ
GYLRNPLAEPGLLGVGASASLGAVVAIYSGLAAGFALALPLCALAGALIAVVLVGVLAGRAAHPLTLILAGIAVSSLATA
LTSLALNLSTNPFAAMEIVFWMLGSLENRSMSHVLLAGPFIALGWVLLARLGPALDALTLGEEAAATLGISLGRTRALVV
LGTASAVGAATAVAGAVGFIGLVVPHLLRPLVGGRPSRLLAASTLGGAAMLLVTDLAVRLIAPERDLKLGVVTALVGAPF
FLWLLARMRKDAL

Sequences:

>Translated_333_residues
MGGDRAFAALLAGLGLLVVALFAVALLVGPAGLAPRAALVALISGDASPAALVMREIRLPRALLALLVGGSLGLSGAALQ
GYLRNPLAEPGLLGVGASASLGAVVAIYSGLAAGFALALPLCALAGALIAVVLVGVLAGRAAHPLTLILAGIAVSSLATA
LTSLALNLSTNPFAAMEIVFWMLGSLENRSMSHVLLAGPFIALGWVLLARLGPALDALTLGEEAAATLGISLGRTRALVV
LGTASAVGAATAVAGAVGFIGLVVPHLLRPLVGGRPSRLLAASTLGGAAMLLVTDLAVRLIAPERDLKLGVVTALVGAPF
FLWLLARMRKDAL
>Mature_332_residues
GGDRAFAALLAGLGLLVVALFAVALLVGPAGLAPRAALVALISGDASPAALVMREIRLPRALLALLVGGSLGLSGAALQG
YLRNPLAEPGLLGVGASASLGAVVAIYSGLAAGFALALPLCALAGALIAVVLVGVLAGRAAHPLTLILAGIAVSSLATAL
TSLALNLSTNPFAAMEIVFWMLGSLENRSMSHVLLAGPFIALGWVLLARLGPALDALTLGEEAAATLGISLGRTRALVVL
GTASAVGAATAVAGAVGFIGLVVPHLLRPLVGGRPSRLLAASTLGGAAMLLVTDLAVRLIAPERDLKLGVVTALVGAPFF
LWLLARMRKDAL

Specific function: Part of the binding-protein-dependent transport system for citrate-dependent Fe(3+). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=277, Percent_Identity=42.5992779783394, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1788004, Length=278, Percent_Identity=40.6474820143885, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1790741, Length=286, Percent_Identity=37.4125874125874, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786805, Length=316, Percent_Identity=38.2911392405063, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786804, Length=231, Percent_Identity=35.4978354978355, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=29.4964028776978, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33049; Mature: 32918

Theoretical pI: Translated: 11.45; Mature: 11.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGDRAFAALLAGLGLLVVALFAVALLVGPAGLAPRAALVALISGDASPAALVMREIRLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RALLALLVGGSLGLSGAALQGYLRNPLAEPGLLGVGASASLGAVVAIYSGLAAGFALALP
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHH
LCALAGALIAVVLVGVLAGRAAHPLTLILAGIAVSSLATALTSLALNLSTNPFAAMEIVF
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
WMLGSLENRSMSHVLLAGPFIALGWVLLARLGPALDALTLGEEAAATLGISLGRTRALVV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCEEEEE
LGTASAVGAATAVAGAVGFIGLVVPHLLRPLVGGRPSRLLAASTLGGAAMLLVTDLAVRL
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHH
IAPERDLKLGVVTALVGAPFFLWLLARMRKDAL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GGDRAFAALLAGLGLLVVALFAVALLVGPAGLAPRAALVALISGDASPAALVMREIRLP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RALLALLVGGSLGLSGAALQGYLRNPLAEPGLLGVGASASLGAVVAIYSGLAAGFALALP
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHH
LCALAGALIAVVLVGVLAGRAAHPLTLILAGIAVSSLATALTSLALNLSTNPFAAMEIVF
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
WMLGSLENRSMSHVLLAGPFIALGWVLLARLGPALDALTLGEEAAATLGISLGRTRALVV
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCEEEEE
LGTASAVGAATAVAGAVGFIGLVVPHLLRPLVGGRPSRLLAASTLGGAAMLLVTDLAVRL
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHH
IAPERDLKLGVVTALVGAPFFLWLLARMRKDAL
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2651410; 7610040; 9278503 [H]