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The map label for this gene is sugE [H]

Identifier: 83591612

GI number: 83591612

Start: 337010

End: 337321

Strand: Direct

Name: sugE [H]

Synonym: Rru_A0272

Alternate gene names: 83591612

Gene position: 337010-337321 (Clockwise)

Preceding gene: 83591611

Following gene: 83591616

Centisome position: 7.74

GC content: 64.42

Gene sequence:

>312_bases
ATGGCTTGGGTTTTTCTGGTTCTCGCCGGTTTATGCGAAGTGGGGTGGGCGGTCGGTTTGAAGATGACCGAGGGGTTCAC
CCGGTTGGTTCCCTCGCTGCTCACGGCTTTGGCGATGATCGCCAGCCTGGGGCTGCTGGGATTGGCCCTGCGCAGCCTGC
CTTTGGGTGTCGGCTACGGCATCTGGGTGGGGATCGGCACCGTCGGGGCGGCGGTCGCCGGCATGGCGCTGTTTGGCGAG
GCGGTCAGCGTGGTCAAACTGGCCTCGCTCGGTCTGATCATCGTCGGGCTCATCGGCTTGAAGATCGGCTGA

Upstream 100 bases:

>100_bases
GCCTCTGAGGCGAGACTTGTGTTCGTCAGGCGGGGACGACCCCGCTGGAGGTGTTTTTCAGGCGGGGACGACCCCGCCAT
GGATCCAGAGGGAGGCATCC

Downstream 100 bases:

>100_bases
GGCGATAAAAAAAGGGGGCCTTCGCGGGCCCCCTTTGCCGGTGGGATCGGAGCTTTCGCCCCGGGATCCTTAATACATGT
GCTGGCCGCCGTTGATCGAC

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 103; Mature: 102

Protein sequence:

>103_residues
MAWVFLVLAGLCEVGWAVGLKMTEGFTRLVPSLLTALAMIASLGLLGLALRSLPLGVGYGIWVGIGTVGAAVAGMALFGE
AVSVVKLASLGLIIVGLIGLKIG

Sequences:

>Translated_103_residues
MAWVFLVLAGLCEVGWAVGLKMTEGFTRLVPSLLTALAMIASLGLLGLALRSLPLGVGYGIWVGIGTVGAAVAGMALFGE
AVSVVKLASLGLIIVGLIGLKIG
>Mature_102_residues
AWVFLVLAGLCEVGWAVGLKMTEGFTRLVPSLLTALAMIASLGLLGLALRSLPLGVGYGIWVGIGTVGAAVAGMALFGEA
VSVVKLASLGLIIVGLIGLKIG

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=103, Percent_Identity=56.3106796116505, Blast_Score=118, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10336; Mature: 10205

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWVFLVLAGLCEVGWAVGLKMTEGFTRLVPSLLTALAMIASLGLLGLALRSLPLGVGYG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWVGIGTVGAAVAGMALFGEAVSVVKLASLGLIIVGLIGLKIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AWVFLVLAGLCEVGWAVGLKMTEGFTRLVPSLLTALAMIASLGLLGLALRSLPLGVGYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
IWVGIGTVGAAVAGMALFGEAVSVVKLASLGLIIVGLIGLKIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]