Click here to switch to the map view.

The map label for this gene is ispH [H]

Identifier: 83591399

GI number: 83591399

Start: 66362

End: 67372

Strand: Direct

Name: ispH [H]

Synonym: Rru_A0059

Alternate gene names: 83591399

Gene position: 66362-67372 (Clockwise)

Preceding gene: 83591396

Following gene: 83591400

Centisome position: 1.52

GC content: 65.97

Gene sequence:

>1011_bases
GTGCAACCCGAGCGTCCAGACGAAGGAACCAGCGACGTGAGCGACGAGAAGCCCATCCGCGTCATCCTGGCCAATCCACG
CGGTTTTTGTGCCGGTGTCACCCGGGCCATCGAGATCGTCGATAAGTGCCTGGAGCTTTACGGGCCGCCGGTCTATGTCC
GCCACGAGATCGTCCACAACAAGCATGTGGTCGACAGCCTGCGGGCGCGCGGCGCGGTTTTCGTCGACGAGCTCGATGAA
GTGCCCCATGGCGCGGTCACCGTGTTCAGCGCCCACGGCGTGTCCAAGGCGGTGATCAACGACGCCAAGCAGCGCCAGTT
GCCGGTGGTCGACGCCACCTGTCCGCTGGTGTCGAAGGTCCATAAGGAAGGCCAGAACCACGCCGCGCGCGGCCGCGAGG
TCGTTCTGATCGGCCATGCCGGCCATCCCGAGGTCGAGGGCACCCAGGGCCAGATCCCCGGCGGCGTCTATCTGGTGAGC
GCCGCTTCCGATGTGGATGGCTTGGTGGTGCGCGATCCCGAGAATCTGGCCTATGTCACCCAGACCACGCTGTCGGTCGA
CGATACCCGCGAAGTGATCGAAGCCCTGAAGCTGCGCTTTCCCGCCATCGTCGGTCCCGATGTCAAAGACATCTGCTATG
CCACCCAGAACCGCCAGTCGGCGGTGCGCGAGATCGCCCGCGAGGCCGATCTGCTGCTGGTCGTCGGCTCGCGCAATTCC
TCCAATTCCAACCGGCTGCGCGAGATCGGCGCCGAAATGGGCAAGCCGTCGTTCCTGATCGCCGATGCCGAAGCCCTGCG
CCCGGAATGGATGGAGGGCGTGGCCACCGTCGCCGTCACCGCCGGCGCCTCGGCCCCCGAGGCCCTGGTTCAGGGGTTGA
TCGACCGCTTGGGGGACTTCGGCCGGGTCGAGGTGATCGAACAGGCCGGGGTGGAGGAACACACCCAGTTCAAGCTGCCC
CGCATCCTGCAGGACGGCGAACGCATAAAGGCCGACGAAAGCGTCGCCTAG

Upstream 100 bases:

>100_bases
GCTTCGATCGCGATCTCCCAACCTTGATTGGGCCCCCTGGGGGGTGCCCCCTGTCGGGGATCGGCGCCCTGGGACCCCCC
TGCGGTCCGGGGAAAGCCTT

Downstream 100 bases:

>100_bases
GGCAAATCCCCGAGCATTCTTTAACCAGAGTGCGCCGGCGATTTGCTTGACCATCAAGATTTTAGAGCAGGAAGCGCGGA
CCAGATTTCGCGCTCCCTGC

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MQPERPDEGTSDVSDEKPIRVILANPRGFCAGVTRAIEIVDKCLELYGPPVYVRHEIVHNKHVVDSLRARGAVFVDELDE
VPHGAVTVFSAHGVSKAVINDAKQRQLPVVDATCPLVSKVHKEGQNHAARGREVVLIGHAGHPEVEGTQGQIPGGVYLVS
AASDVDGLVVRDPENLAYVTQTTLSVDDTREVIEALKLRFPAIVGPDVKDICYATQNRQSAVREIAREADLLLVVGSRNS
SNSNRLREIGAEMGKPSFLIADAEALRPEWMEGVATVAVTAGASAPEALVQGLIDRLGDFGRVEVIEQAGVEEHTQFKLP
RILQDGERIKADESVA

Sequences:

>Translated_336_residues
MQPERPDEGTSDVSDEKPIRVILANPRGFCAGVTRAIEIVDKCLELYGPPVYVRHEIVHNKHVVDSLRARGAVFVDELDE
VPHGAVTVFSAHGVSKAVINDAKQRQLPVVDATCPLVSKVHKEGQNHAARGREVVLIGHAGHPEVEGTQGQIPGGVYLVS
AASDVDGLVVRDPENLAYVTQTTLSVDDTREVIEALKLRFPAIVGPDVKDICYATQNRQSAVREIAREADLLLVVGSRNS
SNSNRLREIGAEMGKPSFLIADAEALRPEWMEGVATVAVTAGASAPEALVQGLIDRLGDFGRVEVIEQAGVEEHTQFKLP
RILQDGERIKADESVA
>Mature_336_residues
MQPERPDEGTSDVSDEKPIRVILANPRGFCAGVTRAIEIVDKCLELYGPPVYVRHEIVHNKHVVDSLRARGAVFVDELDE
VPHGAVTVFSAHGVSKAVINDAKQRQLPVVDATCPLVSKVHKEGQNHAARGREVVLIGHAGHPEVEGTQGQIPGGVYLVS
AASDVDGLVVRDPENLAYVTQTTLSVDDTREVIEALKLRFPAIVGPDVKDICYATQNRQSAVREIAREADLLLVVGSRNS
SNSNRLREIGAEMGKPSFLIADAEALRPEWMEGVATVAVTAGASAPEALVQGLIDRLGDFGRVEVIEQAGVEEHTQFKLP
RILQDGERIKADESVA

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

Organism=Escherichia coli, GI1786212, Length=309, Percent_Identity=58.5760517799353, Blast_Score=368, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 36282; Mature: 36282

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPERPDEGTSDVSDEKPIRVILANPRGFCAGVTRAIEIVDKCLELYGPPVYVRHEIVHN
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
KHVVDSLRARGAVFVDELDEVPHGAVTVFSAHGVSKAVINDAKQRQLPVVDATCPLVSKV
HHHHHHHHHCCCEEEHHHHCCCCCEEEEEECCCCHHHHHCCHHHHCCCEECCCCHHHHHH
HKEGQNHAARGREVVLIGHAGHPEVEGTQGQIPGGVYLVSAASDVDGLVVRDPENLAYVT
HHCCCCHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCEEEEE
QTTLSVDDTREVIEALKLRFPAIVGPDVKDICYATQNRQSAVREIAREADLLLVVGSRNS
EEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCC
SNSNRLREIGAEMGKPSFLIADAEALRPEWMEGVATVAVTAGASAPEALVQGLIDRLGDF
CCHHHHHHHHHHHCCCCEEEECHHHHCHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCC
GRVEVIEQAGVEEHTQFKLPRILQDGERIKADESVA
CHHHHHHHCCCCHHHHHCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQPERPDEGTSDVSDEKPIRVILANPRGFCAGVTRAIEIVDKCLELYGPPVYVRHEIVHN
CCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
KHVVDSLRARGAVFVDELDEVPHGAVTVFSAHGVSKAVINDAKQRQLPVVDATCPLVSKV
HHHHHHHHHCCCEEEHHHHCCCCCEEEEEECCCCHHHHHCCHHHHCCCEECCCCHHHHHH
HKEGQNHAARGREVVLIGHAGHPEVEGTQGQIPGGVYLVSAASDVDGLVVRDPENLAYVT
HHCCCCHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCEEEEE
QTTLSVDDTREVIEALKLRFPAIVGPDVKDICYATQNRQSAVREIAREADLLLVVGSRNS
EEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCC
SNSNRLREIGAEMGKPSFLIADAEALRPEWMEGVATVAVTAGASAPEALVQGLIDRLGDF
CCHHHHHHHHHHHCCCCEEEECHHHHCHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCC
GRVEVIEQAGVEEHTQFKLPRILQDGERIKADESVA
CHHHHHHHCCCCHHHHHCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA