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The map label for this gene is selA

Identifier: 83591320

GI number: 83591320

Start: 2610075

End: 2611487

Strand: Reverse

Name: selA

Synonym: Moth_2504

Alternate gene names: 83591320

Gene position: 2611487-2610075 (Counterclockwise)

Preceding gene: 83591322

Following gene: 83591319

Centisome position: 99.34

GC content: 59.02

Gene sequence:

>1413_bases
ATGGAATCCAGGAACTTATTGCGGCAATTGCCGGCGGTAGATCAATTATTACAGCATCCCCGGCTAAAGGATCTTAGCCG
GGAAAACTATAAAATGGTACTGGCTCTTACCCGCCAGGTCCTGGATGATTGGCGCCTGAAGATAAAAAACGGGGCTACCA
CCATACCTGATCCAGGTCAATTAGCACGGGAAATAGAAAATAGATACCATGAGGCAGGCCGCAGTAGTTTACGGCCGGTA
ATCAACGCCACCGGTGTGGTTTTACATACCAACCTGGGCCGGGCTATTTTAAGCCCGGCCGCCCGGGCAGCAGCCCTGAC
GGCAGCCGGGCGCTATACCAACCTGGAATATGATCTGGAGAAGGGGCAGCGCGGCAATCGCTACAGCCATGTAACAGGGC
TGTTGAAGGAACTTACAGGGGCGGAAGAAGCCCTGGTGGTCAACAATAATGCCGCCGCCGTCCTCCTGGCCCTGTCGACC
CTGGCGGCAGGACGGGAGACCATTATTTCCCGGGGCCAGCTGGTGGAGATCGGGGGTTCCTTCCGAATACCGGAGGTCAT
GGGCCAGAGCGGTACCAGACTGGTGGAAGTGGGTACGACTAATAAAACCTACATCCATGATTATGAAAGAGCTGTGGGTC
CGGATACGGCTCTACTGCTCAAGGTCCATCCCAGTAACTATCGTATCCAGGGGTTTACCCGGGAAGTCACCACTGCTGAA
CTGGTGGAACTGGGGCGCCGTGTGGGGGTGCCGGTCATGGAAGACCTGGGCAGCGGCTTTCTTATCGACCTGGAGGCCTA
TGGTATAACCGGAGAACCGACAGTCCAGGCAGAAATAAACCAGGGAGTAGACGTAGTAACCTTCAGCGGCGATAAATTAC
TGGGAGGACCCCAGGCGGGCATTATTGTCGGCCGCCGGGACCTGGTAGCGGCCATGGCCGGCCATCCTCTCACCAGAGCC
CTGCGGATTGATAAAATGAACCTGGCCGCCCTGGAGGCGACCTTGCGGGCTTACCGCAATCCGGACCGGGCCGTTAAAGA
GATCCCCACCCTGGCGGCCCTGGTGGCTTTACCGGAGGACCTGCGCCTCCGGGCCGAGGAGCTACAAAAATTGCTGACCA
GCGTACTTGGTTCCCGGGCCAGGGTTGGGTTGATGCCTACTACCTCTCAGGCCGGCGGCGGTTCCCTGCCTGTAACTGAA
CTACCATCCTGGGCCATAACCATCCGTCCTGAACAAGGAGGAGCAGCCGGACTGGTAACTGCCCTCCGCCGGACGGACCC
ACCGGTCCTGGCGCGGGTCCAGGACGACCTCCTGCTCCTTGACGTCAGGACTCTGTTGCCGGGCGAGGGCGAGGAACTCG
CCCGGGCCCTGGTTCAGGCCCTGGAGGGAGCCGTCCATGGTGGTGAGTCGTAA

Upstream 100 bases:

>100_bases
GAAGGAAACGGGTAAAAAAAGTTGGAACTGGGTTGTCCAGTTCCAACTTTTTTAGCGGCGGGTTATAATAACAATTAAGT
ATATAAGCGGAGGCACATCA

Downstream 100 bases:

>100_bases
CTGGCTAGCGAGCAAAATATGGTGCTGTATGGGTAGCATGGATATTTTTGGTATCTTTTACAAAGGCGCCTTCTGGGGAC
CTGCATTAAACAAGAACACC

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MESRNLLRQLPAVDQLLQHPRLKDLSRENYKMVLALTRQVLDDWRLKIKNGATTIPDPGQLAREIENRYHEAGRSSLRPV
INATGVVLHTNLGRAILSPAARAAALTAAGRYTNLEYDLEKGQRGNRYSHVTGLLKELTGAEEALVVNNNAAAVLLALST
LAAGRETIISRGQLVEIGGSFRIPEVMGQSGTRLVEVGTTNKTYIHDYERAVGPDTALLLKVHPSNYRIQGFTREVTTAE
LVELGRRVGVPVMEDLGSGFLIDLEAYGITGEPTVQAEINQGVDVVTFSGDKLLGGPQAGIIVGRRDLVAAMAGHPLTRA
LRIDKMNLAALEATLRAYRNPDRAVKEIPTLAALVALPEDLRLRAEELQKLLTSVLGSRARVGLMPTTSQAGGGSLPVTE
LPSWAITIRPEQGGAAGLVTALRRTDPPVLARVQDDLLLLDVRTLLPGEGEELARALVQALEGAVHGGES

Sequences:

>Translated_470_residues
MESRNLLRQLPAVDQLLQHPRLKDLSRENYKMVLALTRQVLDDWRLKIKNGATTIPDPGQLAREIENRYHEAGRSSLRPV
INATGVVLHTNLGRAILSPAARAAALTAAGRYTNLEYDLEKGQRGNRYSHVTGLLKELTGAEEALVVNNNAAAVLLALST
LAAGRETIISRGQLVEIGGSFRIPEVMGQSGTRLVEVGTTNKTYIHDYERAVGPDTALLLKVHPSNYRIQGFTREVTTAE
LVELGRRVGVPVMEDLGSGFLIDLEAYGITGEPTVQAEINQGVDVVTFSGDKLLGGPQAGIIVGRRDLVAAMAGHPLTRA
LRIDKMNLAALEATLRAYRNPDRAVKEIPTLAALVALPEDLRLRAEELQKLLTSVLGSRARVGLMPTTSQAGGGSLPVTE
LPSWAITIRPEQGGAAGLVTALRRTDPPVLARVQDDLLLLDVRTLLPGEGEELARALVQALEGAVHGGES
>Mature_470_residues
MESRNLLRQLPAVDQLLQHPRLKDLSRENYKMVLALTRQVLDDWRLKIKNGATTIPDPGQLAREIENRYHEAGRSSLRPV
INATGVVLHTNLGRAILSPAARAAALTAAGRYTNLEYDLEKGQRGNRYSHVTGLLKELTGAEEALVVNNNAAAVLLALST
LAAGRETIISRGQLVEIGGSFRIPEVMGQSGTRLVEVGTTNKTYIHDYERAVGPDTALLLKVHPSNYRIQGFTREVTTAE
LVELGRRVGVPVMEDLGSGFLIDLEAYGITGEPTVQAEINQGVDVVTFSGDKLLGGPQAGIIVGRRDLVAAMAGHPLTRA
LRIDKMNLAALEATLRAYRNPDRAVKEIPTLAALVALPEDLRLRAEELQKLLTSVLGSRARVGLMPTTSQAGGGSLPVTE
LPSWAITIRPEQGGAAGLVTALRRTDPPVLARVQDDLLLLDVRTLLPGEGEELARALVQALEGAVHGGES

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family

Homologues:

Organism=Escherichia coli, GI2367248, Length=450, Percent_Identity=50.2222222222222, Blast_Score=382, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SELA_MOOTA (Q2RFK3)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_431329.1
- ProteinModelPortal:   Q2RFK3
- STRING:   Q2RFK3
- GeneID:   3832776
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_2504
- NMPDR:   fig|264732.9.peg.2535
- eggNOG:   COG1921
- HOGENOM:   HBG564950
- OMA:   KRGDRDD
- PhylomeDB:   Q2RFK3
- ProtClustDB:   PRK04311
- BioCyc:   MTHE264732:MOTH_2504-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00423
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534
- Gene3D:   G3DSA:3.40.640.10
- TIGRFAMs:   TIGR00474

Pfam domain/function: PF03841 SelA; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.9.1.1

Molecular weight: Translated: 50591; Mature: 50591

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESRNLLRQLPAVDQLLQHPRLKDLSRENYKMVLALTRQVLDDWRLKIKNGATTIPDPGQ
CCCHHHHHHCCHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCHHH
LAREIENRYHEAGRSSLRPVINATGVVLHTNLGRAILSPAARAAALTAAGRYTNLEYDLE
HHHHHHHHHHHHHHHHCCHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEECC
KGQRGNRYSHVTGLLKELTGAEEALVVNNNAAAVLLALSTLAAGRETIISRGQLVEIGGS
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHCCCCEEEECCC
FRIPEVMGQSGTRLVEVGTTNKTYIHDYERAVGPDTALLLKVHPSNYRIQGFTREVTTAE
CCCHHHHCCCCCEEEEECCCCCCEEEHHHHHCCCCEEEEEEECCCCEEEEEEEHHHHHHH
LVELGRRVGVPVMEDLGSGFLIDLEAYGITGEPTVQAEINQGVDVVTFSGDKLLGGPQAG
HHHHHHHCCCCHHHHCCCCEEEEEEEECCCCCCEEEEECCCCEEEEEECCCEECCCCCCC
IIVGRRDLVAAMAGHPLTRALRIDKMNLAALEATLRAYRNPDRAVKEIPTLAALVALPED
EEECHHHHHHHHHCCCHHHHHEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHH
LRLRAEELQKLLTSVLGSRARVGLMPTTSQAGGGSLPVTELPSWAITIRPEQGGAAGLVT
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
ALRRTDPPVLARVQDDLLLLDVRTLLPGEGEELARALVQALEGAVHGGES
HHHHCCCCCEEHHCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MESRNLLRQLPAVDQLLQHPRLKDLSRENYKMVLALTRQVLDDWRLKIKNGATTIPDPGQ
CCCHHHHHHCCHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCHHH
LAREIENRYHEAGRSSLRPVINATGVVLHTNLGRAILSPAARAAALTAAGRYTNLEYDLE
HHHHHHHHHHHHHHHHCCHHHCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEECC
KGQRGNRYSHVTGLLKELTGAEEALVVNNNAAAVLLALSTLAAGRETIISRGQLVEIGGS
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHCCCCEEEECCC
FRIPEVMGQSGTRLVEVGTTNKTYIHDYERAVGPDTALLLKVHPSNYRIQGFTREVTTAE
CCCHHHHCCCCCEEEEECCCCCCEEEHHHHHCCCCEEEEEEECCCCEEEEEEEHHHHHHH
LVELGRRVGVPVMEDLGSGFLIDLEAYGITGEPTVQAEINQGVDVVTFSGDKLLGGPQAG
HHHHHHHCCCCHHHHCCCCEEEEEEEECCCCCCEEEEECCCCEEEEEECCCEECCCCCCC
IIVGRRDLVAAMAGHPLTRALRIDKMNLAALEATLRAYRNPDRAVKEIPTLAALVALPED
EEECHHHHHHHHHCCCHHHHHEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHH
LRLRAEELQKLLTSVLGSRARVGLMPTTSQAGGGSLPVTELPSWAITIRPEQGGAAGLVT
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
ALRRTDPPVLARVQDDLLLLDVRTLLPGEGEELARALVQALEGAVHGGES
HHHHCCCCCEEHHCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA