Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 83591254

GI number: 83591254

Start: 2555188

End: 2555934

Strand: Reverse

Name: map [H]

Synonym: Moth_2438

Alternate gene names: 83591254

Gene position: 2555934-2555188 (Counterclockwise)

Preceding gene: 83591255

Following gene: 83591253

Centisome position: 97.23

GC content: 55.42

Gene sequence:

>747_bases
ATGATTATTTTAAAATCGCGCCGGGAAATAGCCCTGATGCGGGAGGCAGGCCGGATAGTCGCCGGTGCCCTGGCCAAACT
ACAGGAGCATATAGCTCCCGGCATCACTACCGGCGAGCTGGACCGGATTGCCGAGGAGTATATCCGCCGGCATGACGCCG
TGCCGGCCTTCAAAGGTTATCACGGCTTTCCCGCCAGCATCTGTGCGTCAGTGAACGAGGAAGTTGTCCACGGGATCCCG
GGTTTAAAGAAGCTGGTAGCAGGAGATATTATTAGTATTGACATTGGCGTGGTAAAAAATGGTTATGTCGGTGATTCGGC
TGCAACCTTTCCAGTTGGAGACATTGATTCCGGCAAAAAGCAGTTGCTTGCTGCTACCCAGGCTGCTCTTCAGGAAGGCA
TAAAGAAGGCGGTAGTCGGGAATCGCCTGACGGATATCTCCCATGCCATCCAGGCCTTCGTCGAAGCCAGGGGATTTTCA
GTAGTGCGAGATTACGTGGGTCACGGTGTGGGCCGTGCCATGCATGAAGACCCCCAGGTTCCCAACTTCGGACCCCCAGG
TTACGGTCCCCGACTGCGGGTGGGAATGGTCCTGGCCATCGAGCCTATGGTCAATGCAGGCACCCATGAAGTATATACCC
TGCCCAACCGCTGGACGGTGGTAACCAGGGACGGGCAACCTTCGGCTCACTTTGAGCATACAGTAGCGATAACGGAAAAC
GGGCCGGAAATACTGACGCTACTCTAA

Upstream 100 bases:

>100_bases
ACTACTACCGGCAGCGCGGTCTTTTAAAGGAAATTGACGGCAGCCAGGCCATCCCGGCGGTAATCCTGGCTATAGGCAGG
GCCCTGGGAAGAGACTGGCA

Downstream 100 bases:

>100_bases
CTTGCTGGATGGAGGCGGAGGTTATGCCAGCAGGACAACTGCAAGTTGGGCAACTGGTTTTTTCGCGGGCCGGCAGGGAT
CGCGGTCATCCCTTCCTGGT

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MIILKSRREIALMREAGRIVAGALAKLQEHIAPGITTGELDRIAEEYIRRHDAVPAFKGYHGFPASICASVNEEVVHGIP
GLKKLVAGDIISIDIGVVKNGYVGDSAATFPVGDIDSGKKQLLAATQAALQEGIKKAVVGNRLTDISHAIQAFVEARGFS
VVRDYVGHGVGRAMHEDPQVPNFGPPGYGPRLRVGMVLAIEPMVNAGTHEVYTLPNRWTVVTRDGQPSAHFEHTVAITEN
GPEILTLL

Sequences:

>Translated_248_residues
MIILKSRREIALMREAGRIVAGALAKLQEHIAPGITTGELDRIAEEYIRRHDAVPAFKGYHGFPASICASVNEEVVHGIP
GLKKLVAGDIISIDIGVVKNGYVGDSAATFPVGDIDSGKKQLLAATQAALQEGIKKAVVGNRLTDISHAIQAFVEARGFS
VVRDYVGHGVGRAMHEDPQVPNFGPPGYGPRLRVGMVLAIEPMVNAGTHEVYTLPNRWTVVTRDGQPSAHFEHTVAITEN
GPEILTLL
>Mature_248_residues
MIILKSRREIALMREAGRIVAGALAKLQEHIAPGITTGELDRIAEEYIRRHDAVPAFKGYHGFPASICASVNEEVVHGIP
GLKKLVAGDIISIDIGVVKNGYVGDSAATFPVGDIDSGKKQLLAATQAALQEGIKKAVVGNRLTDISHAIQAFVEARGFS
VVRDYVGHGVGRAMHEDPQVPNFGPPGYGPRLRVGMVLAIEPMVNAGTHEVYTLPNRWTVVTRDGQPSAHFEHTVAITEN
GPEILTLL

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=245, Percent_Identity=39.5918367346939, Blast_Score=184, Evalue=7e-47,
Organism=Homo sapiens, GI40385867, Length=247, Percent_Identity=36.8421052631579, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=46.7741935483871, Blast_Score=225, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI71996291, Length=235, Percent_Identity=39.5744680851064, Blast_Score=184, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6323273, Length=247, Percent_Identity=38.4615384615385, Blast_Score=166, Evalue=4e-42,
Organism=Drosophila melanogaster, GI21355531, Length=238, Percent_Identity=40.3361344537815, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24583427, Length=245, Percent_Identity=37.1428571428571, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 26591; Mature: 26591

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILKSRREIALMREAGRIVAGALAKLQEHIAPGITTGELDRIAEEYIRRHDAVPAFKGY
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
HGFPASICASVNEEVVHGIPGLKKLVAGDIISIDIGVVKNGYVGDSAATFPVGDIDSGKK
CCCHHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCCCHHH
QLLAATQAALQEGIKKAVVGNRLTDISHAIQAFVEARGFSVVRDYVGHGVGRAMHEDPQV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
PNFGPPGYGPRLRVGMVLAIEPMVNAGTHEVYTLPNRWTVVTRDGQPSAHFEHTVAITEN
CCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEEECC
GPEILTLL
CCEEEEEC
>Mature Secondary Structure
MIILKSRREIALMREAGRIVAGALAKLQEHIAPGITTGELDRIAEEYIRRHDAVPAFKGY
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
HGFPASICASVNEEVVHGIPGLKKLVAGDIISIDIGVVKNGYVGDSAATFPVGDIDSGKK
CCCHHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCCCHHH
QLLAATQAALQEGIKKAVVGNRLTDISHAIQAFVEARGFSVVRDYVGHGVGRAMHEDPQV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
PNFGPPGYGPRLRVGMVLAIEPMVNAGTHEVYTLPNRWTVVTRDGQPSAHFEHTVAITEN
CCCCCCCCCCCEEEEEEEEEECCCCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEEECC
GPEILTLL
CCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192928; 11058132 [H]