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The map label for this gene is alr1 [H]

Identifier: 83591223

GI number: 83591223

Start: 2526354

End: 2527583

Strand: Reverse

Name: alr1 [H]

Synonym: Moth_2407

Alternate gene names: 83591223

Gene position: 2527583-2526354 (Counterclockwise)

Preceding gene: 83591224

Following gene: 83591222

Centisome position: 96.15

GC content: 64.96

Gene sequence:

>1230_bases
ATGGACCTGGCAAAGCTGACGGAACTGGCCGGACCCCGCTGGATCACCATTGAAGCGACAGCCCTGGCCCACAACCTCAA
AGCCGTTAAAGCTTTACTCGCTCCCTCGACCCGCCTCCTGGCCGTTATCAAGGCCGACGCCTACGGCGCCGGCGCCGTAG
AGGTGGCGCGCATCTTCCTGGACGCAGGGGCGGATTACCTGGGGGTAACCACCCTGGCCGAGGGGCTGGAGTTGCGCCGG
GCCGGCATTGCAGCCCCCGTTCTCCTCATGAGTCCCCTCCTGCCGGAAGAGCTACCGGCAGCCATAGCTGCCGGGCTCAC
CCTAACTGTGAGCAGCCGTTCCGGCGCCGAGGCGATTGCTGCCGCGGCGGCAGCGACCGGGCACCGGGCCCGGGTACACC
TGAAAGTAGAGACCGGGTTGCAGCGGACAGGCCTGGAAGCGGCAGCAGTAGCGCCCCTGGCGCGGGAGATCCTCACCTGG
CCCGGCGTAGAACTGGAGGGCGTCTACAGCCATCTGGCCGAGGCCGCCCGGCCGGCGGCAGCCCGGCGGCAGATGGCCTG
TTTTCAGCAGGTCCTCGCCGAACTGGAGGAGGAGCATATAGCTATCCCCTTGAGGCATATCTGCAACAGCACCGGTCTCC
TTACCCACCCGGAGATGCATCTGGACATGGTCAGAACAGGCACCCTCCTCTACGGCCAGTTCCCCTACCAGGCCCCCCGC
CGGGGACTGGCATTAAAAGACCCCTGGCAGTTTAAAGCCCGTATCCTCTTTATTCACGACGTAGCCGCCGGTACCCCGGT
GGGTTACGGCGGTGACTACGTTGTGAAAAAAGCCACCCGCCTGGCCGTCATCCCGGTGGGTTATGCCGACGGTTTTGCCC
TGACGGCCGTTGCCCGGCCGAAAAACCTGAACGACCTGGCCCGCTACCTGGTCAAGACATTCCTCGCCTACCTGGGTCGG
GGCGGGGGCGAAGGGACCACCGTGATCATAGGCGGCCGGACGGCACCTGTGGTAGGCCGGGTGGGGATGCAACTCTCCAT
GGTCGATGTCGGCCACCTGCCTGAGGTAGAGGTGGGCCAAATAGTAACTCTGGATATACGCCGCCCGACAGCCAGCAGCC
GTCTACCCCGGGTCTACTGCCGGGAGGGACACCCCTACCTGGTGCGGACTACCACCGGAGAACTCCTGCCGGTGGACGCA
CCGCACCTTTCCCCGGGAGTTAATAGTTAA

Upstream 100 bases:

>100_bases
CTTTCGTCGCCTCCTCTTCTGGAGGAAAAAAGCCAGGGCAGCAGAGGAGTGATCCCGAATATTTTTTTAACAGGCAAGGC
AAGGTGGTATCTTTTTTAGT

Downstream 100 bases:

>100_bases
ATACAAAAATTTAATTGATTAAGCAGGAATCTGGCAACAATCACCGAATACTTTTATTAGCGAAGTGGTAGCGAAAAAGC
GGAGCGGGTAAAGGGGGTAT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MDLAKLTELAGPRWITIEATALAHNLKAVKALLAPSTRLLAVIKADAYGAGAVEVARIFLDAGADYLGVTTLAEGLELRR
AGIAAPVLLMSPLLPEELPAAIAAGLTLTVSSRSGAEAIAAAAAATGHRARVHLKVETGLQRTGLEAAAVAPLAREILTW
PGVELEGVYSHLAEAARPAAARRQMACFQQVLAELEEEHIAIPLRHICNSTGLLTHPEMHLDMVRTGTLLYGQFPYQAPR
RGLALKDPWQFKARILFIHDVAAGTPVGYGGDYVVKKATRLAVIPVGYADGFALTAVARPKNLNDLARYLVKTFLAYLGR
GGGEGTTVIIGGRTAPVVGRVGMQLSMVDVGHLPEVEVGQIVTLDIRRPTASSRLPRVYCREGHPYLVRTTTGELLPVDA
PHLSPGVNS

Sequences:

>Translated_409_residues
MDLAKLTELAGPRWITIEATALAHNLKAVKALLAPSTRLLAVIKADAYGAGAVEVARIFLDAGADYLGVTTLAEGLELRR
AGIAAPVLLMSPLLPEELPAAIAAGLTLTVSSRSGAEAIAAAAAATGHRARVHLKVETGLQRTGLEAAAVAPLAREILTW
PGVELEGVYSHLAEAARPAAARRQMACFQQVLAELEEEHIAIPLRHICNSTGLLTHPEMHLDMVRTGTLLYGQFPYQAPR
RGLALKDPWQFKARILFIHDVAAGTPVGYGGDYVVKKATRLAVIPVGYADGFALTAVARPKNLNDLARYLVKTFLAYLGR
GGGEGTTVIIGGRTAPVVGRVGMQLSMVDVGHLPEVEVGQIVTLDIRRPTASSRLPRVYCREGHPYLVRTTTGELLPVDA
PHLSPGVNS
>Mature_409_residues
MDLAKLTELAGPRWITIEATALAHNLKAVKALLAPSTRLLAVIKADAYGAGAVEVARIFLDAGADYLGVTTLAEGLELRR
AGIAAPVLLMSPLLPEELPAAIAAGLTLTVSSRSGAEAIAAAAAATGHRARVHLKVETGLQRTGLEAAAVAPLAREILTW
PGVELEGVYSHLAEAARPAAARRQMACFQQVLAELEEEHIAIPLRHICNSTGLLTHPEMHLDMVRTGTLLYGQFPYQAPR
RGLALKDPWQFKARILFIHDVAAGTPVGYGGDYVVKKATRLAVIPVGYADGFALTAVARPKNLNDLARYLVKTFLAYLGR
GGGEGTTVIIGGRTAPVVGRVGMQLSMVDVGHLPEVEVGQIVTLDIRRPTASSRLPRVYCREGHPYLVRTTTGELLPVDA
PHLSPGVNS

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=357, Percent_Identity=31.0924369747899, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=28.328611898017, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43420; Mature: 43420

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAKLTELAGPRWITIEATALAHNLKAVKALLAPSTRLLAVIKADAYGAGAVEVARIFL
CCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHH
DAGADYLGVTTLAEGLELRRAGIAAPVLLMSPLLPEELPAAIAAGLTLTVSSRSGAEAIA
HCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCHHHHH
AAAAATGHRARVHLKVETGLQRTGLEAAAVAPLAREILTWPGVELEGVYSHLAEAARPAA
HHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHH
ARRQMACFQQVLAELEEEHIAIPLRHICNSTGLLTHPEMHLDMVRTGTLLYGQFPYQAPR
HHHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCC
RGLALKDPWQFKARILFIHDVAAGTPVGYGGDYVVKKATRLAVIPVGYADGFALTAVARP
CCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHEECCCEEEEEEECCCCCEEEEEEECC
KNLNDLARYLVKTFLAYLGRGGGEGTTVIIGGRTAPVVGRVGMQLSMVDVGHLPEVEVGQ
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHCCCEEEEEECCCCCCCCCCC
IVTLDIRRPTASSRLPRVYCREGHPYLVRTTTGELLPVDAPHLSPGVNS
EEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCEEECCCCCCCCCCCC
>Mature Secondary Structure
MDLAKLTELAGPRWITIEATALAHNLKAVKALLAPSTRLLAVIKADAYGAGAVEVARIFL
CCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHH
DAGADYLGVTTLAEGLELRRAGIAAPVLLMSPLLPEELPAAIAAGLTLTVSSRSGAEAIA
HCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHCCEEEEEECCCCHHHHH
AAAAATGHRARVHLKVETGLQRTGLEAAAVAPLAREILTWPGVELEGVYSHLAEAARPAA
HHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHH
ARRQMACFQQVLAELEEEHIAIPLRHICNSTGLLTHPEMHLDMVRTGTLLYGQFPYQAPR
HHHHHHHHHHHHHHHHHHHEEEEHHHHCCCCCCCCCCHHHHHHHCCCEEEEECCCCCCCC
RGLALKDPWQFKARILFIHDVAAGTPVGYGGDYVVKKATRLAVIPVGYADGFALTAVARP
CCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCHHEECCCEEEEEEECCCCCEEEEEEECC
KNLNDLARYLVKTFLAYLGRGGGEGTTVIIGGRTAPVVGRVGMQLSMVDVGHLPEVEVGQ
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHCCCEEEEEECCCCCCCCCCC
IVTLDIRRPTASSRLPRVYCREGHPYLVRTTTGELLPVDAPHLSPGVNS
EEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]