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The map label for this gene is fba [H]

Identifier: 83591220

GI number: 83591220

Start: 2524133

End: 2524993

Strand: Reverse

Name: fba [H]

Synonym: Moth_2404

Alternate gene names: 83591220

Gene position: 2524993-2524133 (Counterclockwise)

Preceding gene: 83591221

Following gene: 83591219

Centisome position: 96.05

GC content: 62.25

Gene sequence:

>861_bases
ATGCCGTTAGTTACCTTGGCCGAAGTTCTGCGGGAAGCCGATACCGGCGGCTACGCCGTAGGTGCCTTCAACTGCAACAA
CATGGAAATCGTCCAGGCCATTATCAACGCTGCTGTTACCGCGCAAGCCCCGGTCATCATCCAGGCCAGCCAGGGGGCCA
TCAAGTACGCGGGGCTGGAGTACATAACCTCCCTGGTACGGACGGCGGCCAGTCAAGCGCCAGTACCGGTGGTCCTCCAC
CTGGACCACGGCACGGACTTTGAGCAGGTCTTGCGTTGTCTGCGGGCCGGCTTTACCTCGGTGATGATCGACGGCTCCAA
ATACCCCCTGGAAGAAAACATCGCCCTCACCAGGAAGGTAGTAGAGATTGCCCACGCCATGGGTGCCTCGGTGGAGGGGG
AGCTGGGACGCATCGGCGGTACCGAGGAACAAATCAAGGTCTCGGAGAGGGAAGCCACCATGACCGACCCGGAGGAGGCC
CAGCGGTTCGCTCGGGAGACCGGGGTTGATGCCCTGGCTGTTGCCATCGGCACGGCCCACGGCCGCTACCACGGCACTCC
CAGACTGGATTTTGAGCGCCTGGCGACCATCGACCGCCTGGTACCGACGCCTATAGTCCTCCACGGTTCTTCCGGGGTGC
CTGATGACGATATCCGCCGCGCCGTCGAACTGGGCGTCCGTAAAATCAACATCGACACCGATATCCGCATCGCCTTTATC
GAGGCCACCCGCACCGCCCTGGACGCCAATCCCGACGAGATCGACCCGCGGAAGGTCCTGGGACCGGCGAGGGATGCCGC
CAGCAAGGTCATCAGCCATAAGATGCAGGTCTTCGGCTGCGCCGGCAGGGTAAAAAAATAG

Upstream 100 bases:

>100_bases
CGACGAGGCAGGTCCCGGCAAGGGCCGGCGCCGCCGCCAGAAATCCCCGGTATGATTCATCATAAACCCAGGGAAAATAC
AGGATAAAGGAGATGAAGCC

Downstream 100 bases:

>100_bases
GCAGTTGCATATTTCTTCACCGGCGTGAAAACCTAATGGTGAACGCCAAAAGGAGGTGGGGGAATATGGCAGGAATCAAA
TGCGGCGTGGAGGAATGCCA

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPLVTLAEVLREADTGGYAVGAFNCNNMEIVQAIINAAVTAQAPVIIQASQGAIKYAGLEYITSLVRTAASQAPVPVVLH
LDHGTDFEQVLRCLRAGFTSVMIDGSKYPLEENIALTRKVVEIAHAMGASVEGELGRIGGTEEQIKVSEREATMTDPEEA
QRFARETGVDALAVAIGTAHGRYHGTPRLDFERLATIDRLVPTPIVLHGSSGVPDDDIRRAVELGVRKINIDTDIRIAFI
EATRTALDANPDEIDPRKVLGPARDAASKVISHKMQVFGCAGRVKK

Sequences:

>Translated_286_residues
MPLVTLAEVLREADTGGYAVGAFNCNNMEIVQAIINAAVTAQAPVIIQASQGAIKYAGLEYITSLVRTAASQAPVPVVLH
LDHGTDFEQVLRCLRAGFTSVMIDGSKYPLEENIALTRKVVEIAHAMGASVEGELGRIGGTEEQIKVSEREATMTDPEEA
QRFARETGVDALAVAIGTAHGRYHGTPRLDFERLATIDRLVPTPIVLHGSSGVPDDDIRRAVELGVRKINIDTDIRIAFI
EATRTALDANPDEIDPRKVLGPARDAASKVISHKMQVFGCAGRVKK
>Mature_285_residues
PLVTLAEVLREADTGGYAVGAFNCNNMEIVQAIINAAVTAQAPVIIQASQGAIKYAGLEYITSLVRTAASQAPVPVVLHL
DHGTDFEQVLRCLRAGFTSVMIDGSKYPLEENIALTRKVVEIAHAMGASVEGELGRIGGTEEQIKVSEREATMTDPEEAQ
RFARETGVDALAVAIGTAHGRYHGTPRLDFERLATIDRLVPTPIVLHGSSGVPDDDIRRAVELGVRKINIDTDIRIAFIE
ATRTALDANPDEIDPRKVLGPARDAASKVISHKMQVFGCAGRVKK

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=284, Percent_Identity=43.6619718309859, Blast_Score=258, Evalue=5e-70,
Organism=Escherichia coli, GI87082041, Length=283, Percent_Identity=42.756183745583, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1788072, Length=276, Percent_Identity=36.231884057971, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789293, Length=288, Percent_Identity=28.125, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322790, Length=281, Percent_Identity=26.6903914590747, Blast_Score=83, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 30729; Mature: 30597

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVTLAEVLREADTGGYAVGAFNCNNMEIVQAIINAAVTAQAPVIIQASQGAIKYAGLE
CCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHH
YITSLVRTAASQAPVPVVLHLDHGTDFEQVLRCLRAGFTSVMIDGSKYPLEENIALTRKV
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
VEIAHAMGASVEGELGRIGGTEEQIKVSEREATMTDPEEAQRFARETGVDALAVAIGTAH
HHHHHHHCCCCCCCCCCCCCCHHHEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
GRYHGTPRLDFERLATIDRLVPTPIVLHGSSGVPDDDIRRAVELGVRKINIDTDIRIAFI
CCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCEEEECCCCEEEEEE
EATRTALDANPDEIDPRKVLGPARDAASKVISHKMQVFGCAGRVKK
EEHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PLVTLAEVLREADTGGYAVGAFNCNNMEIVQAIINAAVTAQAPVIIQASQGAIKYAGLE
CHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHH
YITSLVRTAASQAPVPVVLHLDHGTDFEQVLRCLRAGFTSVMIDGSKYPLEENIALTRKV
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHH
VEIAHAMGASVEGELGRIGGTEEQIKVSEREATMTDPEEAQRFARETGVDALAVAIGTAH
HHHHHHHCCCCCCCCCCCCCCHHHEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCC
GRYHGTPRLDFERLATIDRLVPTPIVLHGSSGVPDDDIRRAVELGVRKINIDTDIRIAFI
CCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCEEEECCCCEEEEEE
EATRTALDANPDEIDPRKVLGPARDAASKVISHKMQVFGCAGRVKK
EEHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA