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The map label for this gene is ywlC [H]

Identifier: 83591211

GI number: 83591211

Start: 2515689

End: 2516747

Strand: Reverse

Name: ywlC [H]

Synonym: Moth_2395

Alternate gene names: 83591211

Gene position: 2516747-2515689 (Counterclockwise)

Preceding gene: 83591212

Following gene: 83591210

Centisome position: 95.74

GC content: 65.16

Gene sequence:

>1059_bases
ATGCGGACCAAATACTTAAAAATCAATCCCCTGGTACCGGAACTGCACAAGATCCGCCTGGCAGCCAAAATCCTGGCCCG
GGGCGGGGTGGTGGCCTTCCCCACGGAGACCGTCTACGGCCTGGGAGCCAACGCCCTGGACGGGCGGGCGGTGCGCCGCA
TCTTCCGGGCCAAGGGGCGCCCGGCTGACAACCCCCTGATCGTTCATATAGCCAGTTTCCAGGATGTCCAGGACCTGGTG
GCCTACCTGCCGCCCCGGGCTACCCTCCTCATGCAGCGCTTCTGGCCCGGTCCCCTCACCCTGATCATGCCGCGCAGCGA
CCTGATCCCTGACGAGGTTACCGCCGGCCTGGATACTGTAGGCCTCCGCATGCCTTCCCACCCGGTGGCCCAGGCCCTCA
TCCGGGCGACCCGCCTCCCCATCGCCGCTCCCAGCGCCAATACCTCGGGACGCCCCAGCCCCACCACCGGCCAGCACGTC
CTGCGCGATTTGCGGGGTAAAATAGACGCTGTAATAGACGGCGGTCCGTCCACCGTGGGGGTAGAATCCACCGTCCTCGA
TCTGACCTCCCCGGTGCCAACTATCCTGCGGCCGGGTGGCATCACCTATGAAGAACTGCAGGCGGTGCTGGGGAAAGTAG
CCATTGACCCGGCCGTCAAAGGCCAGCAGGTGGAACACCCTAAAGCACCGGGGATGAAATACAAGCACTACGCCCCGGCG
GGGGAGGTCTTCCTGGTTACCGGCGATCTGGAGCGGGTGGTGGCCAGGGTACGGGCTCTGGTGGCGGCCTGGCAGCGCCG
CGGCCGGCGGGTGGCCGTCCTGGCGACCAGCGAGACAGCGCCATTCTACCAGGACGAACCCCGGCCCGATTACCTGGAGG
TCCTGGGCAGTCGCCGCCAGCCGGAAACCATCGCCGCCAACCTTTTTGGCGCTTTAAGAAACTGTGACCGTCACCATGCC
GACATCATCCTGGCGGAAACCGTTAAGGAGGAAGGCATCGGCCTGGCCATCATGAACCGGTTGCGTAAATCGGCGGCCAA
CCGCATTATCCGGGCGTAA

Upstream 100 bases:

>100_bases
TTACCAGATTATGCCGGCCGCGATCGTTGTTTCCTGGCTTATCGCCGGGAAGAATAAAGTCAGAGCGGGAAACATAGAGG
TGAAATGGGTGTCTGTAGGT

Downstream 100 bases:

>100_bases
GGAGGAAAATACTTATATGGAGCCGTTGGGTCTTATCCTGGTAGCCGTCGCCCTGGGGACGGATGCCTTTTCCCTGGCTA
CCGGCCTGGCCCTGGGGGGG

Product: translation factor SUA5

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MRTKYLKINPLVPELHKIRLAAKILARGGVVAFPTETVYGLGANALDGRAVRRIFRAKGRPADNPLIVHIASFQDVQDLV
AYLPPRATLLMQRFWPGPLTLIMPRSDLIPDEVTAGLDTVGLRMPSHPVAQALIRATRLPIAAPSANTSGRPSPTTGQHV
LRDLRGKIDAVIDGGPSTVGVESTVLDLTSPVPTILRPGGITYEELQAVLGKVAIDPAVKGQQVEHPKAPGMKYKHYAPA
GEVFLVTGDLERVVARVRALVAAWQRRGRRVAVLATSETAPFYQDEPRPDYLEVLGSRRQPETIAANLFGALRNCDRHHA
DIILAETVKEEGIGLAIMNRLRKSAANRIIRA

Sequences:

>Translated_352_residues
MRTKYLKINPLVPELHKIRLAAKILARGGVVAFPTETVYGLGANALDGRAVRRIFRAKGRPADNPLIVHIASFQDVQDLV
AYLPPRATLLMQRFWPGPLTLIMPRSDLIPDEVTAGLDTVGLRMPSHPVAQALIRATRLPIAAPSANTSGRPSPTTGQHV
LRDLRGKIDAVIDGGPSTVGVESTVLDLTSPVPTILRPGGITYEELQAVLGKVAIDPAVKGQQVEHPKAPGMKYKHYAPA
GEVFLVTGDLERVVARVRALVAAWQRRGRRVAVLATSETAPFYQDEPRPDYLEVLGSRRQPETIAANLFGALRNCDRHHA
DIILAETVKEEGIGLAIMNRLRKSAANRIIRA
>Mature_352_residues
MRTKYLKINPLVPELHKIRLAAKILARGGVVAFPTETVYGLGANALDGRAVRRIFRAKGRPADNPLIVHIASFQDVQDLV
AYLPPRATLLMQRFWPGPLTLIMPRSDLIPDEVTAGLDTVGLRMPSHPVAQALIRATRLPIAAPSANTSGRPSPTTGQHV
LRDLRGKIDAVIDGGPSTVGVESTVLDLTSPVPTILRPGGITYEELQAVLGKVAIDPAVKGQQVEHPKAPGMKYKHYAPA
GEVFLVTGDLERVVARVRALVAAWQRRGRRVAVLATSETAPFYQDEPRPDYLEVLGSRRQPETIAANLFGALRNCDRHHA
DIILAETVKEEGIGLAIMNRLRKSAANRIIRA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=202, Percent_Identity=34.6534653465347, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87081864, Length=200, Percent_Identity=28.5, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI2367210, Length=147, Percent_Identity=32.6530612244898, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537239, Length=208, Percent_Identity=32.2115384615385, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321269, Length=410, Percent_Identity=38.2926829268293, Blast_Score=231, Evalue=9e-62,
Organism=Drosophila melanogaster, GI78707274, Length=182, Percent_Identity=29.6703296703297, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 38295; Mature: 38295

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTKYLKINPLVPELHKIRLAAKILARGGVVAFPTETVYGLGANALDGRAVRRIFRAKGR
CCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHCCC
PADNPLIVHIASFQDVQDLVAYLPPRATLLMQRFWPGPLTLIMPRSDLIPDEVTAGLDTV
CCCCCEEEEEECHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCCHHH
GLRMPSHPVAQALIRATRLPIAAPSANTSGRPSPTTGQHVLRDLRGKIDAVIDGGPSTVG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCC
VESTVLDLTSPVPTILRPGGITYEELQAVLGKVAIDPAVKGQQVEHPKAPGMKYKHYAPA
CCHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCC
GEVFLVTGDLERVVARVRALVAAWQRRGRRVAVLATSETAPFYQDEPRPDYLEVLGSRRQ
CCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHCCCCC
PETIAANLFGALRNCDRHHADIILAETVKEEGIGLAIMNRLRKSAANRIIRA
CHHHHHHHHHHHHCCCHHHHCEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRTKYLKINPLVPELHKIRLAAKILARGGVVAFPTETVYGLGANALDGRAVRRIFRAKGR
CCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEECCHHHHCCCCCCCCHHHHHHHHHHCCC
PADNPLIVHIASFQDVQDLVAYLPPRATLLMQRFWPGPLTLIMPRSDLIPDEVTAGLDTV
CCCCCEEEEEECHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCCHHH
GLRMPSHPVAQALIRATRLPIAAPSANTSGRPSPTTGQHVLRDLRGKIDAVIDGGPSTVG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCC
VESTVLDLTSPVPTILRPGGITYEELQAVLGKVAIDPAVKGQQVEHPKAPGMKYKHYAPA
CCHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCC
GEVFLVTGDLERVVARVRALVAAWQRRGRRVAVLATSETAPFYQDEPRPDYLEVLGSRRQ
CCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHCCCCC
PETIAANLFGALRNCDRHHADIILAETVKEEGIGLAIMNRLRKSAANRIIRA
CHHHHHHHHHHHHCCCHHHHCEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]