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The map label for this gene is ywlE [H]

Identifier: 83591209

GI number: 83591209

Start: 2514397

End: 2515083

Strand: Reverse

Name: ywlE [H]

Synonym: Moth_2393

Alternate gene names: 83591209

Gene position: 2515083-2514397 (Counterclockwise)

Preceding gene: 83591210

Following gene: 83591208

Centisome position: 95.67

GC content: 60.7

Gene sequence:

>687_bases
ATGCCTGGGATTCTTTTTGTCTGCACTGGAAATACCTGCCGGAGCAGTATGGCGGCAGCCATAGCCGCAAAACTGGCTAA
GGAGCGCGGCCTGGACGTAACCATCAGTTCAGCCGGCCTGGCAGCCAGGGAAGGAGACCCGGCCACACCGGAAGCCGTCC
AGGCCCTGGCTGAGATGGGCCTGGACCTTAGCAGCCATCGCGCCCGGCAGTTGACGGCGGCCACAGTCAGGGACGCCGAT
CTTATCCTGACCATGACAGCGGAGCACAGGGAAAGGATACTCCGGGACTACCCTGAGGCCAGGGGTAAAACTTATACCCT
CAAGGAATACGTGCAGGGTCCTGAAGACCCGGCCATGGCGCGGCGGCGCCTGAAACTGGCGGGGGAGATAGCTGCCAGGG
AACAGGAGTTTGCCGCTGCTCACCGCCAGGAACTGGAGGAGCTATACCGGGAAGCCGGCGACGGAGCTTTGAGCCAGGAG
AAGAAAACCAGGTGGCAGCAGCTGGAGGCAGAGCTGACGGCCAGCCTAAAACCCCTGCTGGAGGAATTGGCTCGCATCCA
GGCAGGAGCCAGCCGGGATATAGCCGATCCCTTCGGCCAGCCCCTGGAGGTTTACCGGGCAACAGCCAGGGAACTGGAGC
GGCTTATTAGACAGGCGCTGAGGAAATTTTCACAAGAGAAAAAATAA

Upstream 100 bases:

>100_bases
GGCCGGCGCCTGGGTTCCTTCTTCGGAAACCGGGCCGAGCTTGCCGGTGGCCTGATCCTGGTGGCCATTGGCCTGAAGAT
GCTAGTGGGGGTCTAACCTG

Downstream 100 bases:

>100_bases
GTTTGACAGCAGAGCAGGATTCCGGTTAATTGTGGCGAACATTTAAGTATGGTTTAATATTATGGGGGAGAGATGAAGTG
AAATTGCGCGTAGCTCTGGG

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MPGILFVCTGNTCRSSMAAAIAAKLAKERGLDVTISSAGLAAREGDPATPEAVQALAEMGLDLSSHRARQLTAATVRDAD
LILTMTAEHRERILRDYPEARGKTYTLKEYVQGPEDPAMARRRLKLAGEIAAREQEFAAAHRQELEELYREAGDGALSQE
KKTRWQQLEAELTASLKPLLEELARIQAGASRDIADPFGQPLEVYRATARELERLIRQALRKFSQEKK

Sequences:

>Translated_228_residues
MPGILFVCTGNTCRSSMAAAIAAKLAKERGLDVTISSAGLAAREGDPATPEAVQALAEMGLDLSSHRARQLTAATVRDAD
LILTMTAEHRERILRDYPEARGKTYTLKEYVQGPEDPAMARRRLKLAGEIAAREQEFAAAHRQELEELYREAGDGALSQE
KKTRWQQLEAELTASLKPLLEELARIQAGASRDIADPFGQPLEVYRATARELERLIRQALRKFSQEKK
>Mature_227_residues
PGILFVCTGNTCRSSMAAAIAAKLAKERGLDVTISSAGLAAREGDPATPEAVQALAEMGLDLSSHRARQLTAATVRDADL
ILTMTAEHRERILRDYPEARGKTYTLKEYVQGPEDPAMARRRLKLAGEIAAREQEFAAAHRQELEELYREAGDGALSQEK
KTRWQQLEAELTASLKPLLEELARIQAGASRDIADPFGQPLEVYRATARELERLIRQALRKFSQEKK

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788375, Length=115, Percent_Identity=39.1304347826087, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87081812, Length=119, Percent_Identity=37.8151260504202, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 25242; Mature: 25111

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGILFVCTGNTCRSSMAAAIAAKLAKERGLDVTISSAGLAAREGDPATPEAVQALAEMG
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHC
LDLSSHRARQLTAATVRDADLILTMTAEHRERILRDYPEARGKTYTLKEYVQGPEDPAMA
CCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCHHHCCCEEEHHHHHCCCCCHHHH
RRRLKLAGEIAAREQEFAAAHRQELEELYREAGDGALSQEKKTRWQQLEAELTASLKPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EELARIQAGASRDIADPFGQPLEVYRATARELERLIRQALRKFSQEKK
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PGILFVCTGNTCRSSMAAAIAAKLAKERGLDVTISSAGLAAREGDPATPEAVQALAEMG
CCEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHC
LDLSSHRARQLTAATVRDADLILTMTAEHRERILRDYPEARGKTYTLKEYVQGPEDPAMA
CCHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCHHHCCCEEEHHHHHCCCCCHHHH
RRRLKLAGEIAAREQEFAAAHRQELEELYREAGDGALSQEKKTRWQQLEAELTASLKPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EELARIQAGASRDIADPFGQPLEVYRATARELERLIRQALRKFSQEKK
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7798145; 9384377 [H]