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The map label for this gene is atpD

Identifier: 83591194

GI number: 83591194

Start: 2503058

End: 2504446

Strand: Reverse

Name: atpD

Synonym: Moth_2378

Alternate gene names: 83591194

Gene position: 2504446-2503058 (Counterclockwise)

Preceding gene: 83591195

Following gene: 83591193

Centisome position: 95.27

GC content: 61.41

Gene sequence:

>1389_bases
TTGAACGAAGGACAGGTGGTCCAGGTTATTGGCCCGGTGGTTGACGTCGAATTCGCCAGCGACCGGCTGCCCGACCTGTA
TAACGCCATCACCATTAAAACCGATAAGATTAATATAACCATGGAGGCCATGCAGCACCTGGGCAACAACACCGTCCGCT
GTGTGGCCCTCTCCTCGACCGACGGCCTGCAGCGAGGGATGAAGGCCGTTGACACCGGCCAGCCAATCACCGTACCGGTA
GGCCGGGCTACCCTGGGACGGCTCTTTAACGTCCTGGGAGAACCCATTGACAACCAGGGACCGGTAGAAACCACCGAGAG
GCTGCCCATTCACCGGCCGGCGCCCTCCTTTGAAGAGCAACAGCCTTCTACCGAGGTCCTGGAGACTGGCATCAAGGTGG
TCGACCTCCTGGCGCCCTACGCCAAGGGCGGCAAGATCGGCCTCTTCGGCGGCGCCGGGGTCGGCAAGACGGTCCTCATC
ATGGAACTCATCCGCAACATCGCCTATGAACACGGCGGCTTTTCCGTCTTCAGCGGCGTGGGCGAGCGTACCCGCGAGGG
TAACGACCTCTACCTGGAGATGAAGGAATCCGGGGTTCTCGAAAAGACGGCCCTGGTCTTTGGCCAGATGAACGAACCCC
CGGGTGCCCGCCTGCGGGTGGGTCTTACAGGCCTGACTATGGCCGAGTACTTCCGGGACGCCGAGGGCCAGGACGTTCTC
CTCTTCATCGACAATATCTTTCGCTTCGTGCAGGCCGGTTCCGAGGTTTCCGCCCTCCTGGGCCGGATGCCCTCGGCGGT
GGGTTATCAGCCCACCCTGGCCACAGAGATGGGGGCCCTGCAGGAACGGATTACCTCCACGAAAAAGGGTTCCATCACCT
CCGTGCAAGCTATCTATGTGCCGGCCGACGACCTGACCGACCCGGCCCCGGCGACGACCTTCGCCCATCTGGACGCCACC
ACGGTTCTGTCCCGGCAGATCGCTGAGCTGGGCATCTACCCGGCCGTCGACCCCCTGGACTCCACCTCCCGTATCCTGGA
CCCGCGCGTCCTGGGAGAAGAGCACTACCAGGTGGCCCGGGGCGTCCAGCAGGTACTGCAGCGTTATAAAGAACTTCAGG
ACATTATCGCCATCCTGGGAATGGATGAGCTGTCCGAAGAAGATAAACTCATAGTTGCCCGGGCACGCAAGATCCAGCGT
TTCCTCTCCCAGCCCTTCCACGTAGCCGAGGCTTTTACCGGCCAGCCCGGGGTTTATGTGCCCCTGAAGGAAACCATTCG
CGGTTTCAAAGAGATCCTGGAGGGCCGCCACGACAACCTCCCCGAGCAGGCCTTCTATATGGTCGGGACCATCGACGAAG
CCGTCAAGAAGGGCCAGGAGTTGATGTAG

Upstream 100 bases:

>100_bases
TCACCCTATCCTTCAACCGCGCCCGCCAGGCGGCCATCACCAACGAGATCGTGGAGATCGTCGCCGGGGCAGATGCTTTG
AAGTAAAGGAGGGGACAAGT

Downstream 100 bases:

>100_bases
ATGGCCTCCCTCAACCTGGAGATCATAACTCCCGAGCGGGTGGTCCTGCAGGCGGAAGCCGCCAGCGTCATAGCTCCAGG
TATCCAGGGCTACCTGGGTG

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNEGQVVQVIGPVVDVEFASDRLPDLYNAITIKTDKINITMEAMQHLGNNTVRCVALSSTDGLQRGMKAVDTGQPITVPV
GRATLGRLFNVLGEPIDNQGPVETTERLPIHRPAPSFEEQQPSTEVLETGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLI
MELIRNIAYEHGGFSVFSGVGERTREGNDLYLEMKESGVLEKTALVFGQMNEPPGARLRVGLTGLTMAEYFRDAEGQDVL
LFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPATTFAHLDAT
TVLSRQIAELGIYPAVDPLDSTSRILDPRVLGEEHYQVARGVQQVLQRYKELQDIIAILGMDELSEEDKLIVARARKIQR
FLSQPFHVAEAFTGQPGVYVPLKETIRGFKEILEGRHDNLPEQAFYMVGTIDEAVKKGQELM

Sequences:

>Translated_462_residues
MNEGQVVQVIGPVVDVEFASDRLPDLYNAITIKTDKINITMEAMQHLGNNTVRCVALSSTDGLQRGMKAVDTGQPITVPV
GRATLGRLFNVLGEPIDNQGPVETTERLPIHRPAPSFEEQQPSTEVLETGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLI
MELIRNIAYEHGGFSVFSGVGERTREGNDLYLEMKESGVLEKTALVFGQMNEPPGARLRVGLTGLTMAEYFRDAEGQDVL
LFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPATTFAHLDAT
TVLSRQIAELGIYPAVDPLDSTSRILDPRVLGEEHYQVARGVQQVLQRYKELQDIIAILGMDELSEEDKLIVARARKIQR
FLSQPFHVAEAFTGQPGVYVPLKETIRGFKEILEGRHDNLPEQAFYMVGTIDEAVKKGQELM
>Mature_462_residues
MNEGQVVQVIGPVVDVEFASDRLPDLYNAITIKTDKINITMEAMQHLGNNTVRCVALSSTDGLQRGMKAVDTGQPITVPV
GRATLGRLFNVLGEPIDNQGPVETTERLPIHRPAPSFEEQQPSTEVLETGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLI
MELIRNIAYEHGGFSVFSGVGERTREGNDLYLEMKESGVLEKTALVFGQMNEPPGARLRVGLTGLTMAEYFRDAEGQDVL
LFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYVPADDLTDPAPATTFAHLDAT
TVLSRQIAELGIYPAVDPLDSTSRILDPRVLGEEHYQVARGVQQVLQRYKELQDIIAILGMDELSEEDKLIVARARKIQR
FLSQPFHVAEAFTGQPGVYVPLKETIRGFKEILEGRHDNLPEQAFYMVGTIDEAVKKGQELM

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=464, Percent_Identity=72.8448275862069, Blast_Score=682, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=321, Percent_Identity=28.9719626168224, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI19913428, Length=358, Percent_Identity=26.536312849162, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI19913426, Length=367, Percent_Identity=26.158038147139, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI50345984, Length=385, Percent_Identity=25.4545454545455, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI4757810, Length=385, Percent_Identity=25.4545454545455, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1790170, Length=461, Percent_Identity=71.5835140997831, Blast_Score=679, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=322, Percent_Identity=31.3664596273292, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1790172, Length=389, Percent_Identity=26.7352185089974, Blast_Score=128, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI25144756, Length=464, Percent_Identity=70.9051724137931, Blast_Score=663, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=322, Percent_Identity=29.8136645962733, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17510931, Length=417, Percent_Identity=25.8992805755396, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=350, Percent_Identity=26.5714285714286, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71988080, Length=358, Percent_Identity=25.9776536312849, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=358, Percent_Identity=25.9776536312849, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988074, Length=339, Percent_Identity=25.0737463126844, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=457, Percent_Identity=73.0853391684902, Blast_Score=678, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=353, Percent_Identity=28.8951841359773, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6319370, Length=347, Percent_Identity=25.9365994236311, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320016, Length=263, Percent_Identity=27.3764258555133, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24638766, Length=464, Percent_Identity=72.198275862069, Blast_Score=675, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=466, Percent_Identity=68.2403433476395, Blast_Score=637, Evalue=0.0,
Organism=Drosophila melanogaster, GI20129479, Length=350, Percent_Identity=29.1428571428571, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24583992, Length=321, Percent_Identity=28.9719626168224, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24583988, Length=321, Percent_Identity=28.6604361370716, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24583986, Length=321, Percent_Identity=28.6604361370716, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24583984, Length=321, Percent_Identity=28.6604361370716, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281361666, Length=354, Percent_Identity=26.8361581920904, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24646341, Length=354, Percent_Identity=26.8361581920904, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI17136796, Length=354, Percent_Identity=26.8361581920904, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24658560, Length=358, Percent_Identity=25.6983240223464, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=50, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_MOOTA (Q2RFX9)

Other databases:

- EMBL:   U64318
- EMBL:   CP000232
- RefSeq:   YP_431203.1
- HSSP:   P00829
- ProteinModelPortal:   Q2RFX9
- SMR:   Q2RFX9
- STRING:   Q2RFX9
- GeneID:   3832017
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_2378
- NMPDR:   fig|264732.9.peg.2410
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- PhylomeDB:   Q2RFX9
- ProtClustDB:   PRK09280
- BioCyc:   MTHE264732:MOTH_2378-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 50451; Mature: 50451

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEGQVVQVIGPVVDVEFASDRLPDLYNAITIKTDKINITMEAMQHLGNNTVRCVALSST
CCCCCEEEEECCCCEEECCCCCCCHHHCEEEEEECEEEEEHHHHHHHCCCCEEEEEECCC
DGLQRGMKAVDTGQPITVPVGRATLGRLFNVLGEPIDNQGPVETTERLPIHRPAPSFEEQ
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCC
QPSTEVLETGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELIRNIAYEHGGFSVFSGV
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHC
GERTREGNDLYLEMKESGVLEKTALVFGQMNEPPGARLRVGLTGLTMAEYFRDAEGQDVL
CHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHCCCCCCEEE
LFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYV
EEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
PADDLTDPAPATTFAHLDATTVLSRQIAELGIYPAVDPLDSTSRILDPRVLGEEHYQVAR
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHCHHHHHHHH
GVQQVLQRYKELQDIIAILGMDELSEEDKLIVARARKIQRFLSQPFHVAEAFTGQPGVYV
HHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEE
PLKETIRGFKEILEGRHDNLPEQAFYMVGTIDEAVKKGQELM
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNEGQVVQVIGPVVDVEFASDRLPDLYNAITIKTDKINITMEAMQHLGNNTVRCVALSST
CCCCCEEEEECCCCEEECCCCCCCHHHCEEEEEECEEEEEHHHHHHHCCCCEEEEEECCC
DGLQRGMKAVDTGQPITVPVGRATLGRLFNVLGEPIDNQGPVETTERLPIHRPAPSFEEQ
HHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCCC
QPSTEVLETGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELIRNIAYEHGGFSVFSGV
CCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHC
GERTREGNDLYLEMKESGVLEKTALVFGQMNEPPGARLRVGLTGLTMAEYFRDAEGQDVL
CHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCEEEEEECHHHHHHHHCCCCCCEEE
LFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTKKGSITSVQAIYV
EEHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEE
PADDLTDPAPATTFAHLDATTVLSRQIAELGIYPAVDPLDSTSRILDPRVLGEEHYQVAR
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHCHHHHHHHH
GVQQVLQRYKELQDIIAILGMDELSEEDKLIVARARKIQRFLSQPFHVAEAFTGQPGVYV
HHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEE
PLKETIRGFKEILEGRHDNLPEQAFYMVGTIDEAVKKGQELM
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA